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Search results 1401 to 1460 out of 1460 for Tnfrsf1a

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Type Details Score
Protein
Q545P4
Organism: Mus musculus/domesticus
Length: 474  
Fragment?: false
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Allele
Tnfrsf1a<tm1Blt> | MGI:1861040
Name: tumor necrosis factor receptor superfamily, member 1a; targeted mutation 1, Horst Bluethmann
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
11096118 | J:67984
First Author: Vig E
Year: 2001
Journal: J Biol Chem
Title: SIMPL is a tumor necrosis factor-specific regulator of nuclear factor-kappaB activity.
Volume: 276
Issue: 11
Pages: 7859-66
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Protein
Q9ESJ7
Organism: Mus musculus/domesticus
Length: 259  
Fragment?: false
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Protein
G5E885
Organism: Mus musculus/domesticus
Length: 237  
Fragment?: false
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Publication
17681535 | -
First Author: Graham SC
Year: 2007
Journal: J Mol Biol
Title: Structure of CrmE, a virus-encoded tumour necrosis factor receptor.
Volume: 372
Issue: 3
Pages: 660-71
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Publication
16940541 | -
First Author: Sedger LM
Year: 2006
Journal: J Virol
Title: Poxvirus tumor necrosis factor receptor (TNFR)-like T2 proteins contain a conserved preligand assembly domain that inhibits cellular TNFR1-induced cell death.
Volume: 80
Issue: 18
Pages: 9300-9
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Publication
8091665 | -
First Author: Hu FQ
Year: 1994
Journal: Virology
Title: Cowpox virus contains two copies of an early gene encoding a soluble secreted form of the type II TNF receptor.
Volume: 204
Issue: 1
Pages: 343-56
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Publication
11022793 | -
First Author: Xu X
Year: 2000
Journal: Virus Genes
Title: Myxoma virus expresses a TNF receptor homolog with two distinct functions.
Volume: 21
Issue: 1-2
Pages: 97-109
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Protein Domain
IPR034059 | TNFRSF_N_viral
Type: Domain
Description: Viral TNFR homologues include vaccinia virus (VACV) cytokine response modifier E (CrmE) [], an encoded TNFR that shares significant sequence similarity with mammalian type 2 TNF receptors (TNFSFR1B, p75, TNFR type 2) [], a cowpox virus encoded cytokine-response modifier B (CrmB) [], which is a secreted form of TNF receptor that can contribute to the modification of TNF-mediated antiviral processes, and a myxoma virus (MYXV) T2 (M-T2) protein that binds and inhibits rabbit TNF-alpha []. The CrmE structure confirms that the canonical TNFR fold is adopted, but only one of the two "ligand-binding"loops of TNFRSF1A is conserved, suggesting a mechanism for the higher affinity of poxvirusTNFRs for TNFalpha over lymphotoxin-alpha []. CrmB protein specifically binds TNF-alpha and TNF-beta indicating that cowpox virus seeks to invade antiviral processes mediated by TNF. Intracellular M-T2 blocks virus-induced lymphocyte apoptosis via a highly conserved viral preligand assembly domain (vPLAD), which controls receptor signaling competency prior to ligand binding [].This entry represents the N-terminal domain of viral TNFRs. TNF-receptors are modular proteins. The N-terminal extracellular part contains a cysteine-rich region responsible for ligand-binding. This region is composed of small modules of about 40 residues containing 6 conserved cysteines; the number and type of modules can vary in different members of the family [, , ].
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Protein
A6PWP7
Organism: Mus musculus/domesticus
Length: 263  
Fragment?: true
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Protein
Q99LH6
Organism: Mus musculus/domesticus
Length: 232  
Fragment?: false
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Strain
MGI:6335586 | STOCK Tnfrsf1a<tm1Blt> Tg(Tnf)6074Gkl/Flmg
Attribute String: mutant stock, targeted mutation, transgenic
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Strain
MGI:4834349 | B6.129-Tnfrsf1b<tm1Mwm> Tnfrsf1a<tm1Blt>/Cnrm
Attribute String: targeted mutation, mutant strain, congenic
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Strain
MGI:5707320 | STOCK Tnfrsf1a<tm1Blt> Tg(Gfap-TNF*)K21Gkl/Flmg
Attribute String: mutant stock, transgenic, targeted mutation
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Strain
MGI:4834481 | B6.129P2-Tnfrsf1a<tm1Blt>/Cnrm
Attribute String: mutant strain, congenic, targeted mutation
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Strain
MGI:3622105 | C.129P2-Tnfrsf1a<tm1Blt>
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:6335587 | CBA.Cg-Tnfrsf1a<tm1Blt> Tg(CD2-TNF/HBB)211Gkl/Flmg
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Strain
MGI:5707327 | STOCK Tnfrsf1a<tm1Blt> Tg(CD2/HBB-TNF*)5453Gkl/Flmg
Attribute String: transgenic, targeted mutation, mutant stock
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Strain
MGI:3622106 | B6.129P2-Tnfrsf1a<tm1Blt>
Attribute String: targeted mutation, mutant strain, congenic
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Genotype
Genotype
Symbol: Tnf/Tnf Tnfrsf1a/Tnfrsf1a
Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tnfrsf1a/Tnfrsf1a
Background: C.129P2-Tnfrsf1a
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tnfrsf1a/Tnfrsf1a
Background: B6.129P2-Tnfrsf1a
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tnfrsf1a/Tnfrsf1a
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tnfrsf1a/Tnfrsf1a Tg(Cr2-cre)3Cgn/?
Background: involves: 129P2/OlaHsd * 129S/SvEv
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tnfrsf1a/Tnfrsf1a
Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Gfap-TNF*)K21Gkl/? Tnfrsf1a/Tnfrsf1a<+>
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tnfrsf1a/Tnfrsf1a Tnfrsf1b/Tnfrsf1b
Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ifng/Ifng Tnfrsf1a/Tnfrsf1a Tnfrsf1b/Tnfrsf1b
Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tnfrsf1a/Tnfrsf1a<+>
Background: involves: 129P2/OlaHsd
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tnfrsf1a/Tnfrsf1a
Background: involves: 129P2/OlaHsd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tnfrsf1a/Tnfrsf1a Tnfrsf1b/Tnfrsf1b
Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6NTac
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tnfrsf1a/Tnfrsf1a Tnfrsf1b/Tnfrsf1b Zfp36/Zfp36
Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6NTac
Zygosity: cx
Has Mutant Allele: true
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Strain
MGI:4940825 | NOD.Cg-Tnfrsf1a<tm1Blt> Fas<lpr>
Attribute String: congenic, mutant strain, spontaneous mutation, targeted mutation
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Protein
P25118
Organism: Mus musculus/domesticus
Length: 454  
Fragment?: false
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Protein
Q6QHF0
Organism: Mus musculus/domesticus
Length: 440  
Fragment?: true
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Protein
Q3U479
Organism: Mus musculus/domesticus
Length: 454  
Fragment?: false
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Protein
Q3TVS9
Organism: Mus musculus/domesticus
Length: 454  
Fragment?: false
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Protein
Q6QHF1
Organism: Mus musculus/domesticus
Length: 440  
Fragment?: true
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Publication
20937701 | -
First Author: Yoshimura S
Year: 2010
Journal: J Cell Biol
Title: Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.
Volume: 191
Issue: 2
Pages: 367-81
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Protein
Q80U28
Organism: Mus musculus/domesticus
Length: 1577  
Fragment?: false
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Protein
E9QN47
Organism: Mus musculus/domesticus
Length: 1627  
Fragment?: false
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Protein
A2AGQ6
Organism: Mus musculus/domesticus
Length: 1602  
Fragment?: false
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Protein
A2AGQ9
Organism: Mus musculus/domesticus
Length: 1574  
Fragment?: false
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Protein
A2AGR0
Organism: Mus musculus/domesticus
Length: 1577  
Fragment?: false
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Protein
A2AGQ8
Organism: Mus musculus/domesticus
Length: 1562  
Fragment?: false
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Protein
A2AGQ4
Organism: Mus musculus/domesticus
Length: 1632  
Fragment?: false
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Protein
A2AGQ7
Organism: Mus musculus/domesticus
Length: 1573  
Fragment?: false
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Protein
A2AGQ3
Organism: Mus musculus/domesticus
Length: 1541  
Fragment?: false
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Protein
A0A0R4J1F4
Organism: Mus musculus/domesticus
Length: 1558  
Fragment?: false
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Protein
A6PWP8
Organism: Mus musculus/domesticus
Length: 1115  
Fragment?: false
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Protein
A2AGQ2
Organism: Mus musculus/domesticus
Length: 1554  
Fragment?: false
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Protein
A2AGQ5
Organism: Mus musculus/domesticus
Length: 1593  
Fragment?: false
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Protein
A2AGR1
Organism: Mus musculus/domesticus
Length: 1475  
Fragment?: false
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Publication
9538693 | -
First Author: Naismith JH
Year: 1998
Journal: Trends Biochem Sci
Title: Modularity in the TNF-receptor family.
Volume: 23
Issue: 2
Pages: 74-9
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Publication
11796220 | -
First Author: Bodmer JL
Year: 2002
Journal: Trends Biochem Sci
Title: The molecular architecture of the TNF superfamily.
Volume: 27
Issue: 1
Pages: 19-26
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Publication
8387891 | -
First Author: Banner DW
Year: 1993
Journal: Cell
Title: Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation.
Volume: 73
Issue: 3
Pages: 431-45
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Publication
7482697 | -
First Author: Feinstein E
Year: 1995
Journal: Trends Biochem Sci
Title: The death domain: a module shared by proteins with diverse cellular functions.
Volume: 20
Issue: 9
Pages: 342-4
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Publication
17201679 | -
 
First Author: Park HH
Year: 2007
Journal: Annu Rev Immunol
Title: The death domain superfamily in intracellular signaling of apoptosis and inflammation.
Volume: 25
Pages: 561-86
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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