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Search results 1 to 66 out of 66 for Aph1a

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Category: Publication
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Type Details Score
Publication
15665098 | J:96106
First Author: Serneels L
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Differential contribution of the three Aph1 genes to gamma-secretase activity in vivo.
Volume: 102
Issue: 5
Pages: 1719-24
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Publication
20130175 | J:157933
First Author: Zhao G
Year: 2010
Journal: J Neurosci
Title: Gamma-secretase composed of PS1/Pen2/Aph1a can cleave notch and amyloid precursor protein in the absence of nicastrin.
Volume: 30
Issue: 5
Pages: 1648-56
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Publication
15716592 | J:98573
First Author: Urano Y
Year: 2005
Journal: J Lipid Res
Title: Association of active gamma-secretase complex with lipid rafts.
Volume: 46
Issue: 5
Pages: 904-12
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Publication
27240539 | J:236114
First Author: Wang P
Year: 2016
Journal: Aging Cell
Title: Prostaglandin I2 upregulates the expression of anterior pharynx-defective-1α and anterior pharynx-defective-1β in amyloid precursor protein/presenilin 1 transgenic mice.
Volume: 15
Issue: 5
Pages: 861-71
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Publication
20145246 | J:161717
First Author: Chen AC
Year: 2010
Journal: J Biol Chem
Title: Aph-1 associates directly with full-length and C-terminal fragments of gamma-secretase substrates.
Volume: 285
Issue: 15
Pages: 11378-91
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Publication
12297508 | J:80170
First Author: Lee SF
Year: 2002
Journal: J Biol Chem
Title: Mammalian APH-1 interacts with presenilin and nicastrin and is required for intramembrane proteolysis of amyloid-beta precursor protein and Notch.
Volume: 277
Issue: 47
Pages: 45013-9
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Publication
19716417 | J:155504
First Author: Tan J
Year: 2009
Journal: Neurobiol Dis
Title: Residues at P2-P1 positions of epsilon- and zeta-cleavage sites are important in formation of beta-amyloid peptide.
Volume: 36
Issue: 3
Pages: 453-60
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Publication
12522139 | J:297314
First Author: Luo WJ
Year: 2003
Journal: J Biol Chem
Title: PEN-2 and APH-1 coordinately regulate proteolytic processing of presenilin 1.
Volume: 278
Issue: 10
Pages: 7850-4
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Publication
34879266 | J:321535
First Author: Han J
Year: 2021
Journal: Cell Rep
Title: Aberrant role of pyruvate kinase M2 in the regulation of gamma-secretase and memory deficits in Alzheimer's disease.
Volume: 37
Issue: 10
Pages: 110102
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Publication
19299585 | J:147990
First Author: Serneels L
Year: 2009
Journal: Science
Title: gamma-Secretase heterogeneity in the Aph1 subunit: relevance for Alzheimer's disease.
Volume: 324
Issue: 5927
Pages: 639-42
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Publication
17913918 | J:125592
First Author: Li T
Year: 2007
Journal: J Neurosci
Title: Moderate reduction of gamma-secretase attenuates amyloid burden and limits mechanism-based liabilities.
Volume: 27
Issue: 40
Pages: 10849-59
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Publication
12952904 | J:85474
First Author: Cheng HT
Year: 2003
Journal: Development
Title: Gamma-secretase activity is dispensable for mesenchyme-to-epithelium transition but required for podocyte and proximal tubule formation in developing mouse kidney.
Volume: 130
Issue: 20
Pages: 5031-42
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Publication
20674680 | J:164909
First Author: Sanjo N
Year: 2010
Journal: Neurosci Lett
Title: Localization and trafficking of endogenous anterior pharynx-defective 1, a component of Alzheimer's disease related gamma-secretase.
Volume: 483
Issue: 1
Pages: 53-6
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Publication
34292306 | J:321625
 
First Author: Wouters R
Year: 2021
Journal: J Cell Biol
Title: Assembly of γ-secretase occurs through stable dimers after exit from the endoplasmic reticulum.
Volume: 220
Issue: 9
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Publication
28588032 | J:262463
First Author: Acx H
Year: 2017
Journal: EMBO Mol Med
Title: Inactivation of γ-secretases leads to accumulation of substrates and non-Alzheimer neurodegeneration.
Volume: 9
Issue: 8
Pages: 1088-1099
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Publication
24891237 | J:330097
   
First Author: Fazzari P
Year: 2014
Journal: Elife
Title: Cell autonomous regulation of hippocampal circuitry via Aph1b-γ-secretase/neuregulin 1 signalling.
Volume: 3
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Publication
26299962 | J:265989
First Author: Barão S
Year: 2015
Journal: Cell Rep
Title: Antagonistic Effects of BACE1 and APH1B-γ-Secretase Control Axonal Guidance by Regulating Growth Cone Collapse.
Volume: 12
Issue: 9
Pages: 1367-76
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Publication
26293690 | J:230598
First Author: Yu X
Year: 2015
Journal: FASEB J
Title: By suppressing the expression of anterior pharynx-defective-1α and -1β and inhibiting the aggregation of β-amyloid protein, magnesium ions inhibit the cognitive decline of amyloid precursor protein/presenilin 1 transgenic mice.
Volume: 29
Issue: 12
Pages: 5044-58
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Publication
15634781 | J:95769
First Author: Ma G
Year: 2005
Journal: J Neurosci
Title: APH-1a is the principal mammalian APH-1 isoform present in gamma-secretase complexes during embryonic development.
Volume: 25
Issue: 1
Pages: 192-8
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Publication
35197629 | J:342797
First Author: Ma T
Year: 2022
Journal: Nature
Title: Low-dose metformin targets the lysosomal AMPK pathway through PEN2.
Volume: 603
Issue: 7899
Pages: 159-165
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Publication
15474363 | J:93093
First Author: Hébert SS
Year: 2004
Journal: Neurobiol Dis
Title: Coordinated and widespread expression of gamma-secretase in vivo: evidence for size and molecular heterogeneity.
Volume: 17
Issue: 2
Pages: 260-72
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Publication
27349870 | J:238594
First Author: Biswas S
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Posttranslational proteolytic processing of Leda-1/Pianp involves cleavage by MMPs, ADAM10/17 and gamma-secretase.
Volume: 477
Issue: 4
Pages: 661-666
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Publication
21597003 | J:177000
First Author: Barthet G
Year: 2011
Journal: FASEB J
Title: Inhibitors of γ-secretase stabilize the complex and differentially affect processing of amyloid precursor protein and other substrates.
Volume: 25
Issue: 9
Pages: 2937-46
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Publication
15274632 | J:320147
First Author: Fraering PC
Year: 2004
Journal: Biochemistry
Title: Purification and characterization of the human gamma-secretase complex.
Volume: 43
Issue: 30
Pages: 9774-89
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Publication
10206645 | J:54336
First Author: De Strooper B
Year: 1999
Journal: Nature
Title: A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain.
Volume: 398
Issue: 6727
Pages: 518-22
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Publication
30157441 | J:266640
First Author: Albrecht NE
Year: 2018
Journal: Cell Rep
Title: Rapid and Integrative Discovery of Retina Regulatory Molecules.
Volume: 24
Issue: 9
Pages: 2506-2519
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Publication
30692224 | J:273599
First Author: Cheng S
Year: 2019
Journal: J Neurosci
Title: Conditional Inactivation of Pen-2 in the Developing Neocortex Leads to Rapid Switch of Apical Progenitors to Basal Progenitors.
Volume: 39
Issue: 12
Pages: 2195-2207
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Publication
31609468 | J:286828
First Author: Jiang D
Year: 2020
Journal: J Comp Neurol
Title: Spatiotemporal gene expression patterns reveal molecular relatedness between retinal laminae.
Volume: 528
Issue: 5
Pages: 729-755
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
- | J:157064
     
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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