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Search results 401 to 490 out of 490 for Ehmt2

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Type Details Score
Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 70
Description: N6,N6-dimethyllysine; by EHMT2
Type: modified residue
End: 70
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UniProt Feature
UniProt Feature
Begin: 432
Description: N6-methylated lysine; by EHMT2
Type: modified residue
End: 432
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UniProt Feature
UniProt Feature
Begin: 1
Description: Histone-lysine N-methyltransferase EHMT2
Type: chain
End: 1263
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UniProt Feature
UniProt Feature
Begin: 104
Description: N6-methyllysine; by EHMT2
Type: modified residue
End: 104
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UniProt Feature
UniProt Feature
Begin: 313
Description: N6-methylated lysine; by EHMT2
Type: modified residue
End: 313
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UniProt Feature
UniProt Feature
Begin: 298
Description: N6-methylated lysine; by EHMT2
Type: modified residue
End: 298
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UniProt Feature
UniProt Feature
Begin: 170
Description: N6-methylated lysine; by EHMT2
Type: modified residue
End: 170
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UniProt Feature
UniProt Feature
Begin: 1047
Description: N6-methylated lysine; by EHMT2
Type: modified residue
End: 1047
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UniProt Feature
UniProt Feature
Begin: 444
Description: N6-methylated lysine; by EHMT2
Type: modified residue
End: 444
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HT Sample
GSM2850306
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 2.5
Stage: 3
Structure . Name: 8-cell stage embryo
Notes: maternally depleted Ehmt2
Curation Status: Curated
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HT Sample
GSM2850307
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 2.5
Stage: 3
Structure . Name: 8-cell stage embryo
Notes: maternally depleted Ehmt2
Curation Status: Curated
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HT Sample
GSM2850308
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 2.5
Stage: 3
Structure . Name: 8-cell stage embryo
Notes: maternally depleted Ehmt2
Curation Status: Curated
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HT Sample
GSM2850309
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 2.5
Stage: 3
Structure . Name: 8-cell stage embryo
Notes: maternally depleted Ehmt2
Curation Status: Curated
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HT Sample
GSM2850310
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 2.5
Stage: 3
Structure . Name: 8-cell stage embryo
Notes: maternally depleted Ehmt2
Curation Status: Curated
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HT Sample
GSM2850311
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 2.5
Stage: 3
Structure . Name: 8-cell stage embryo
Notes: maternally depleted Ehmt2
Curation Status: Curated
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HT Sample
GSM2850312
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 2.5
Stage: 3
Structure . Name: 8-cell stage embryo
Notes: maternally depleted Ehmt2
Curation Status: Curated
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HT Sample
GSM2850313
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 2.5
Stage: 3
Structure . Name: 8-cell stage embryo
Notes: maternally depleted Ehmt2
Curation Status: Curated
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HT Sample
GSM2850295
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 2.5
Stage: 3
Structure . Name: 8-cell stage embryo
Notes: maternally inherited Ehmt2
Curation Status: Curated
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HT Sample
GSM2850297
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 2.5
Stage: 3
Structure . Name: 8-cell stage embryo
Notes: maternally inherited Ehmt2
Curation Status: Curated
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HT Sample
GSM2850294
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 2.5
Stage: 3
Structure . Name: 8-cell stage embryo
Notes: maternally inherited Ehmt2
Curation Status: Curated
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HT Sample
GSM2850296
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 2.5
Stage: 3
Structure . Name: 8-cell stage embryo
Notes: maternally inherited Ehmt2
Curation Status: Curated
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HT Sample
GSM2850303
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 2.5
Stage: 3
Structure . Name: 8-cell stage embryo
Notes: maternally inherited Ehmt2
Curation Status: Curated
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HT Sample
GSM2850304
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 2.5
Stage: 3
Structure . Name: 8-cell stage embryo
Notes: maternally depleted Ehmt2
Curation Status: Curated
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HT Sample
GSM2850305
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 2.5
Stage: 3
Structure . Name: 8-cell stage embryo
Notes: maternally depleted Ehmt2
Curation Status: Curated
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HT Sample
GSM2850298
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 2.5
Stage: 3
Structure . Name: 8-cell stage embryo
Notes: maternally inherited Ehmt2
Curation Status: Curated
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HT Sample
GSM2850299
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 2.5
Stage: 3
Structure . Name: 8-cell stage embryo
Notes: maternally inherited Ehmt2
Curation Status: Curated
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HT Sample
GSM2850300
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 2.5
Stage: 3
Structure . Name: 8-cell stage embryo
Notes: maternally inherited Ehmt2
Curation Status: Curated
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HT Sample
GSM2850301
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 2.5
Stage: 3
Structure . Name: 8-cell stage embryo
Notes: maternally inherited Ehmt2
Curation Status: Curated
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HT Sample
GSM2850302
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 2.5
Stage: 3
Structure . Name: 8-cell stage embryo
Notes: maternally inherited Ehmt2
Curation Status: Curated
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Protein
Q9Z148-2
Organism: Mus musculus/domesticus
Length: 1172  
Fragment?: false
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Protein
Q9Z148-3
Organism: Mus musculus/domesticus
Length: 1206  
Fragment?: false
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HT Experiment
GSE153611 | Maternal EHMT2 is essential for homologous chromosome segregation by regulating Cyclin B3 in mouse oocytes
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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UniProt Feature
UniProt Feature
Begin: 186
Description: N6-methyllysine; by EHMT1 and EHMT2
Type: modified residue
End: 186
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HT Experiment
GSE156538 | Whole genome RNA sequencing analysis to measure the effect of Ehmt2 (G9a, Bat8) deficiencies in somite-staged mouse embryos
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE160455 | Total RNA sequencing analysis to measure the effect of Ehmt2 (G9a, Bat8) deficiencies in the placentas of somite-satge matched embryos
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
11707778 | -
First Author: Brown SE
Year: 2001
Journal: Mamm Genome
Title: Novel NG36/G9a gene products encoded within the human and mouse MHC class III regions.
Volume: 12
Issue: 12
Pages: 916-24
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Allele
Ehmt2<tm1Smoc> | MGI:7289461
Name: euchromatic histone lysine N-methyltransferase 2; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Publication
19056828 | J:173043
First Author: Kim JK
Year: 2009
Journal: Nucleic Acids Res
Title: UHRF1 binds G9a and participates in p21 transcriptional regulation in mammalian cells.
Volume: 37
Issue: 2
Pages: 493-505
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HT Experiment
GSE106790 | G9a regulates temporal preimplantation developmental program and lineage segregation in blastocyst
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Strain
MGI:6354759 | C57BL/6J-Ehmt2<tm1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, targeted mutation
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HT Experiment
GSE89801 | BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis and male fertility
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Protein Domain
IPR043550 | EHMT1/EHMT2
Type: Family
Description: Histone-lysine N-methyltransferase EHMT1, () mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin []. H3K9me is a specific tag for repression of epigenetic transcription, recruiting HP1 proteins to methylated histones. EHMT1 also methylates 'Lys-27' of histone H3 (H3K27me), but weakly []. EHMT1 also dimethylates other proteins, including 'Lys-373' of p53 []. EHMT1 forms a heterodimer with EHMT2 [], and is a component of the E2F6.com-1 complex in G0 phase []. EHMT1 contains eight ankyrin repeats which bind the monomethylated RELA subunit of NF-kappa-B, a SET domain which interacts with WIZ [], and a pre-SET domain that binds three zinc ions via cysteine residues [].
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Protein Domain
IPR038035 | EHMT1
Type: Family
Description: Histone-lysine N-methyltransferase EHMT1, () mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin []. H3K9me is a specific tag for repression of epigenetic transcription, recruiting HP1 proteins to methylated histones. EHMT1 also methylates 'Lys-27' of histone H3 (H3K27me), but weakly []. EHMT1 also dimethylates other proteins, including 'Lys-373' of p53 []. EHMT1 forms a heterodimer with EHMT2 [], and is a component of the E2F6.com-1 complex in G0 phase []. EHMT1 contains eight ankyrin repeats which bind the monomethylated RELA subunit of NF-kappa-B, a SET domain which interacts with WIZ [], and a pre-SET domain that binds three zinc ions via cysteine residues [].
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Protein
A0A1B0GXE2
Organism: Mus musculus/domesticus
Length: 286  
Fragment?: true
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Protein
F6WWY8
Organism: Mus musculus/domesticus
Length: 224  
Fragment?: true
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Protein
A0A140LII4
Organism: Mus musculus/domesticus
Length: 232  
Fragment?: true
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Protein
A0A0G2JFI9
Organism: Mus musculus/domesticus
Length: 254  
Fragment?: true
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Protein
Q8C358
Organism: Mus musculus/domesticus
Length: 263  
Fragment?: true
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Protein
A2AIS5
Organism: Mus musculus/domesticus
Length: 362  
Fragment?: true
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Protein
Q8BRN2
Organism: Mus musculus/domesticus
Length: 287  
Fragment?: true
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Protein
Q8C3T0
Organism: Mus musculus/domesticus
Length: 278  
Fragment?: true
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Publication
27373831 | J:239711
First Author: Benevento M
Year: 2016
Journal: Neuron
Title: Histone Methylation by the Kleefstra Syndrome Protein EHMT1 Mediates Homeostatic Synaptic Scaling.
Volume: 91
Issue: 2
Pages: 341-55
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HT Experiment
GSE89010 | Increased H3K9 methylation and impaired expression of Protocadherins are associated with the cognitive dysfunctions of the Kleefstra syndrome
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
28959017 | J:252998
First Author: Vilhais-Neto GC
Year: 2017
Journal: Nat Commun
Title: The WHHERE coactivator complex is required for retinoic acid-dependent regulation of embryonic symmetry.
Volume: 8
Issue: 1
Pages: 728
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Publication
37511136 | J:338828
 
First Author: Gao L
Year: 2023
Journal: Int J Mol Sci
Title: The Novel Role of Zfp296 in Mammalian Embryonic Genome Activation as an H3K9me3 Modulator.
Volume: 24
Issue: 14
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Publication
14656967 | J:86796
First Author: Xie T
Year: 2003
Journal: Genome Res
Title: Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse.
Volume: 13
Issue: 12
Pages: 2621-36
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Protein
A0A0A6YWA0
Organism: Mus musculus/domesticus
Length: 203  
Fragment?: true
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Protein
A0A0A6YXD1
Organism: Mus musculus/domesticus
Length: 107  
Fragment?: true
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Protein
Q6ZPG6
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: true
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Protein
Q3UF17
Organism: Mus musculus/domesticus
Length: 282  
Fragment?: true
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Protein
Q5DW34
Organism: Mus musculus/domesticus
Length: 1296  
Fragment?: false
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Protein
A0A0H2UH19
Organism: Mus musculus/domesticus
Length: 1289  
Fragment?: false
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Protein
Z4YJZ7
Organism: Mus musculus/domesticus
Length: 1288  
Fragment?: false
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Protein
E9Q5A3
Organism: Mus musculus/domesticus
Length: 1248  
Fragment?: false
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Protein
H7CHP8
Organism: Mus musculus/domesticus
Length: 1241  
Fragment?: false
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Protein
Q8BHB2
Organism: Mus musculus/domesticus
Length: 917  
Fragment?: false
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Publication
24129315 | J:306378
First Author: Guo A
Year: 2014
Journal: Mol Cell Proteomics
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
Volume: 13
Issue: 1
Pages: 372-87
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom