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Search results 101 to 197 out of 197 for Ptpn2

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0.027s
Type Details Score
GXD Expression    
Probe: MGI:4355199
Assay Type: Northern blot
Annotation Date: 2009-08-27
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:4355197
Age: postnatal adult
Image: 5
Specimen Label: TE
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:4355072
Assay Type: Northern blot
Annotation Date: 2009-08-27
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:4355200
Age: postnatal adult
Image: 5
Specimen Label: TE
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:4355072
Assay Type: Northern blot
Annotation Date: 2009-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:4355074
Age: postnatal adult
Image: 4
Specimen Label: TH
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4355072
Assay Type: Northern blot
Annotation Date: 2009-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4355074
Age: postnatal adult
Image: 4
Specimen Label: BR
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:4355199
Assay Type: Northern blot
Annotation Date: 2009-08-27
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:4355197
Age: postnatal adult
Image: 5
Specimen Label: OV
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:4355072
Assay Type: Northern blot
Annotation Date: 2009-08-27
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:4355200
Age: postnatal adult
Image: 5
Specimen Label: OV
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:490820
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1733123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827517
Age: embryonic day 14.5
Image: euxassay_001391_01
Specimen Label: euxassay_001391_01
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:490820
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1672823
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4827517
Age: embryonic day 14.5
Image: euxassay_001391_01
Specimen Label: euxassay_001391_01
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:490820
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3090123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827517
Age: embryonic day 14.5
Image: euxassay_001391_01
Note: Originally this result was annotated to a male-specific term, but as the specimen was not sexed, it is likely the data annotator intended to use a non-gender specific term.
Specimen Label: euxassay_001391_01
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:490820
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1790623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827517
Age: embryonic day 14.5
Image: euxassay_001391_01
Specimen Label: euxassay_001391_01
Detected: true
Specimen Num: 1
Publication
First Author: Heinonen KM
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Protein tyrosine phosphatases PTP-1B and TC-PTP play nonredundant roles in macrophage development and IFN-gamma signaling.
Volume: 106
Issue: 23
Pages: 9368-72
Publication
First Author: Bourdeau A
Year: 2013
Journal: Stem Cells
Title: Inhibition of T cell protein tyrosine phosphatase enhances interleukin-18-dependent hematopoietic stem cell expansion.
Volume: 31
Issue: 2
Pages: 293-304
Publication
First Author: Zee T
Year: 2012
Journal: Mol Cell Biol
Title: T-cell protein tyrosine phosphatase regulates bone resorption and whole-body insulin sensitivity through its expression in osteoblasts.
Volume: 32
Issue: 6
Pages: 1080-8
Publication
First Author: Dodd GT
Year: 2019
Journal: Cell Rep
Title: Intranasal Targeting of Hypothalamic PTP1B and TCPTP Reinstates Leptin and Insulin Sensitivity and Promotes Weight Loss in Obesity.
Volume: 28
Issue: 11
Pages: 2905-2922.e5
Publication
First Author: Bettaieb A
Year: 2011
Journal: J Biol Chem
Title: Differential regulation of endoplasmic reticulum stress by protein tyrosine phosphatase 1B and T cell protein tyrosine phosphatase.
Volume: 286
Issue: 11
Pages: 9225-35
Publication
First Author: Galic S
Year: 2005
Journal: Mol Cell Biol
Title: Coordinated regulation of insulin signaling by the protein tyrosine phosphatases PTP1B and TCPTP.
Volume: 25
Issue: 2
Pages: 819-29
Publication
First Author: Dubé N
Year: 2005
Journal: Biochim Biophys Acta
Title: Involvement of the small protein tyrosine phosphatases TC-PTP and PTP1B in signal transduction and diseases: from diabetes, obesity to cell cycle, and cancer.
Volume: 1754
Issue: 1-2
Pages: 108-17
Publication
First Author: Blanquart C
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Protein tyrosine phosphatase-1B and T-cell protein tyrosine phosphatase regulate IGF-2-induced MCF-7 cell migration.
Volume: 392
Issue: 1
Pages: 83-8
Publication
First Author: Simoncic PD
Year: 2006
Journal: Mol Cell Biol
Title: T-cell protein tyrosine phosphatase (Tcptp) is a negative regulator of colony-stimulating factor 1 signaling and macrophage differentiation.
Volume: 26
Issue: 11
Pages: 4149-60
Publication
First Author: ten Hoeve J
Year: 2002
Journal: Mol Cell Biol
Title: Identification of a nuclear Stat1 protein tyrosine phosphatase.
Volume: 22
Issue: 16
Pages: 5662-8
Publication
First Author: Lu X
Year: 2007
Journal: Mol Cell Biol
Title: T-cell protein tyrosine phosphatase, distinctively expressed in activated-B-cell-like diffuse large B-cell lymphomas, is the nuclear phosphatase of STAT6.
Volume: 27
Issue: 6
Pages: 2166-79
Publication
First Author: Galic S
Year: 2003
Journal: Mol Cell Biol
Title: Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP.
Volume: 23
Issue: 6
Pages: 2096-108
Publication
First Author: Nesterovitch AB
Year: 2011
Journal: Am J Pathol
Title: Spontaneous insertion of a b2 element in the ptpn6 gene drives a systemic autoinflammatory disease in mice resembling neutrophilic dermatosis in humans.
Volume: 178
Issue: 4
Pages: 1701-14
Publication
First Author: Young RM
Year: 2009
Journal: Blood
Title: TC-PTP is required for the maintenance of MYC-driven B-cell lymphomas.
Volume: 114
Issue: 24
Pages: 5016-23
Publication    
First Author: Dodd GT
Year: 2018
Journal: Elife
Title: Insulin regulates POMC neuronal plasticity to control glucose metabolism.
Volume: 7
Publication
First Author: Shields BJ
Year: 2013
Journal: Mol Cell Biol
Title: TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers.
Volume: 33
Issue: 3
Pages: 557-70
Publication
First Author: Xu C
Year: 2019
Journal: FASEB J
Title: Protein tyrosine phosphatase 11 acts through RhoA/ROCK to regulate eosinophil accumulation in the allergic airway.
Volume: 33
Issue: 11
Pages: 11706-11720
Publication
First Author: Mattila E
Year: 2005
Journal: Nat Cell Biol
Title: Negative regulation of EGFR signalling through integrin-alpha1beta1-mediated activation of protein tyrosine phosphatase TCPTP.
Volume: 7
Issue: 1
Pages: 78-85
Publication
First Author: Loh K
Year: 2011
Journal: Cell Metab
Title: Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance.
Volume: 14
Issue: 5
Pages: 684-99
Publication
First Author: Dodd GT
Year: 2017
Journal: Cell Metab
Title: A Hypothalamic Phosphatase Switch Coordinates Energy Expenditure with Feeding.
Volume: 26
Issue: 2
Pages: 375-393.e7
Publication
First Author: Dodd GT
Year: 2015
Journal: Cell
Title: Leptin and insulin act on POMC neurons to promote the browning of white fat.
Volume: 160
Issue: 1-2
Pages: 88-104
Publication
First Author: Dodd GT
Year: 2018
Journal: Diabetes
Title: TCPTP Regulates Insulin Signaling in AgRP Neurons to Coordinate Glucose Metabolism With Feeding.
Volume: 67
Issue: 7
Pages: 1246-1257
Publication
First Author: Pouliot P
Year: 2009
Journal: Immunology
Title: The role of protein tyrosine phosphatases in the regulation of allergic asthma: implication of TC-PTP and PTP-1B in the modulation of disease development.
Volume: 128
Issue: 4
Pages: 534-42
Publication
First Author: Karlsson S
Year: 2006
Journal: Mol Biol Cell
Title: Loss of T-cell protein tyrosine phosphatase induces recycling of the platelet-derived growth factor (PDGF) beta-receptor but not the PDGF alpha-receptor.
Volume: 17
Issue: 11
Pages: 4846-55
Publication
First Author: Mo W
Year: 2008
Journal: Mol Cell
Title: Nuclear beta-arrestin1 functions as a scaffold for the dephosphorylation of STAT1 and moderates the antiviral activity of IFN-gamma.
Volume: 31
Issue: 5
Pages: 695-707
Publication
First Author: Persson C
Year: 2004
Journal: Mol Cell Biol
Title: Site-selective regulation of platelet-derived growth factor beta receptor tyrosine phosphorylation by T-cell protein tyrosine phosphatase.
Volume: 24
Issue: 5
Pages: 2190-201
Publication
First Author: Grohmann M
Year: 2018
Journal: Cell
Title: Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC.
Volume: 175
Issue: 5
Pages: 1289-1306.e20
Publication
First Author: Ren F
Year: 2015
Journal: FEBS Lett
Title: Nuclear termination of STAT3 signaling through SIPAR (STAT3-Interacting Protein As a Repressor)-dependent recruitment of T cell tyrosine phosphatase TC-PTP.
Volume: 589
Issue: 15
Pages: 1890-6
Publication
First Author: Kaneko Y
Year: 1993
Journal: Biochem Biophys Res Commun
Title: Identification of protein tyrosine phosphatases expressed in murine male germ cells.
Volume: 197
Issue: 2
Pages: 625-31
Publication  
First Author: Cho JH
Year: 2016
Journal: Nat Commun
Title: CD45-mediated control of TCR tuning in naïve and memory CD8+ T cells.
Volume: 7
Pages: 13373
Publication  
First Author: Dodd GT
Year: 2021
Journal: Sci Adv
Title: Insulin signaling in AgRP neurons regulates meal size to limit glucose excursions and insulin resistance.
Volume: 7
Issue: 9
Publication
First Author: Kim DJ
Year: 2010
Journal: PLoS One
Title: Protein tyrosine phosphatases, TC-PTP, SHP1, and SHP2, cooperate in rapid dephosphorylation of Stat3 in keratinocytes following UVB irradiation.
Volume: 5
Issue: 4
Pages: e10290
Publication
First Author: Papadakis AI
Year: 2010
Journal: Cancer Res
Title: eIF2{alpha} Kinase PKR modulates the hypoxic response by Stat3-dependent transcriptional suppression of HIF-1{alpha}.
Volume: 70
Issue: 20
Pages: 7820-9
Publication
First Author: Wang X
Year: 2023
Journal: Neuron
Title: Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis.
Volume: 111
Issue: 2
Pages: 236-255.e7
Publication
First Author: Huang K
Year: 1996
Journal: Oncogene
Title: Cloning and characterization of PTP-K1, a novel nonreceptor protein tyrosine phosphatase highly expressed in bone marrow.
Volume: 13
Issue: 7
Pages: 1567-73
Publication
First Author: Kaneko K
Year: 2016
Journal: Cell Rep
Title: Neuronal Rap1 Regulates Energy Balance, Glucose Homeostasis, and Leptin Actions.
Volume: 16
Issue: 11
Pages: 3003-3015
Publication
First Author: Reinhard J
Year: 2009
Journal: Exp Brain Res
Title: Protein tyrosine phosphatases expression during development of mouse superior colliculus.
Volume: 199
Issue: 3-4
Pages: 279-97
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
Publication
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
Allele
Name: protein tyrosine phosphatase, non-receptor type 2; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Interaction Experiment
Description: In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target.
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Allele
Name: protein tyrosine phosphatase, non-receptor type 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Publication
First Author: Manguso RT
Year: 2017
Journal: Nature
Title: In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target.
Volume: 547
Issue: 7664
Pages: 413-418
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Publication
First Author: Kramer F
Year: 2020
Journal: Haematologica
Title: Platelet-derived growth factor receptor β activation and regulation in murine myelofibrosis.
Volume: 105
Issue: 8
Pages: 2083-2094
Publication
First Author: Wei J
Year: 2019
Journal: Nature
Title: Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy.
Volume: 576
Issue: 7787
Pages: 471-476