The function of SZRD1 is not clear. It may act as a tumour suppressor in cervical cancer []. Homologues are found in metazoa and fungi. Homologues contain a SUZ domain, which is a conserved RNA-binding domain enriched in positively charged amino acids and first characterised in the Caenorhabditis elegans protein SZY-20 where it has been shown to bind RNA and allow their localization to the centrosome [].
