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Search results 201 to 300 out of 379 for Shc1

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Type Details Score
Publication
10748054 | J:113920
First Author: Poe JC
Year: 2000
Journal: J Biol Chem
Title: CD22 forms a quaternary complex with SHIP, Grb2, and Shc. A pathway for regulation of B lymphocyte antigen receptor-induced calcium flux.
Volume: 275
Issue: 23
Pages: 17420-7
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Publication
12925710 | J:177164
First Author: Vindis C
Year: 2003
Journal: J Cell Biol
Title: EphB1 recruits c-Src and p52Shc to activate MAPK/ERK and promote chemotaxis.
Volume: 162
Issue: 4
Pages: 661-71
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Publication
7689150 | J:14183
First Author: Suen KL
Year: 1993
Journal: Mol Cell Biol
Title: Molecular cloning of the mouse grb2 gene: differential interaction of the Grb2 adaptor protein with epidermal growth factor and nerve growth factor receptors.
Volume: 13
Issue: 9
Pages: 5500-12
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Publication
15467833 | J:93419
First Author: Abou-Rjaily GA
Year: 2004
Journal: J Clin Invest
Title: CEACAM1 modulates epidermal growth factor receptor--mediated cell proliferation.
Volume: 114
Issue: 7
Pages: 944-52
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Publication
12367511 | J:130626
First Author: Minichiello L
Year: 2002
Journal: Neuron
Title: Mechanism of TrkB-mediated hippocampal long-term potentiation.
Volume: 36
Issue: 1
Pages: 121-37
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Publication
17626887 | J:122927
First Author: Hardy WR
Year: 2007
Journal: Science
Title: Combinatorial ShcA docking interactions support diversity in tissue morphogenesis.
Volume: 317
Issue: 5835
Pages: 251-6
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Publication
15899871 | J:99096
First Author: Tachibana K
Year: 2005
Journal: Mol Cell Biol
Title: Selective role of a distinct tyrosine residue on Tie2 in heart development and early hematopoiesis.
Volume: 25
Issue: 11
Pages: 4693-702
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Publication
22081964 | J:217274
First Author: Giorgio M
Year: 2012
Journal: Aging Cell
Title: The p66Shc knocked out mice are short lived under natural condition.
Volume: 11
Issue: 1
Pages: 162-8
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Publication
25075770 | J:278464
First Author: Shahzad K
Year: 2015
Journal: Kidney Int
Title: Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy.
Volume: 87
Issue: 1
Pages: 74-84
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Publication
28137876 | J:240935
First Author: Kumar S
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Sirtuin1-regulated lysine acetylation of p66Shc governs diabetes-induced vascular oxidative stress and endothelial dysfunction.
Volume: 114
Issue: 7
Pages: 1714-1719
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Publication
24270983 | J:229061
First Author: Albiero M
Year: 2014
Journal: Diabetes
Title: Diabetes causes bone marrow autonomic neuropathy and impairs stem cell mobilization via dysregulated p66Shc and Sirt1.
Volume: 63
Issue: 4
Pages: 1353-65
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Publication
27789474 | J:249234
First Author: Li Q
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: P66Shc-Induced MicroRNA-34a Causes Diabetic Endothelial Dysfunction by Downregulating Sirtuin1.
Volume: 36
Issue: 12
Pages: 2394-2403
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Publication
11877420 | J:76516
First Author: Tarr PE
Year: 2002
Journal: J Biol Chem
Title: Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc.
Volume: 277
Issue: 19
Pages: 16798-804
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Publication
26680585 | J:230032
First Author: Muthusamy BP
Year: 2015
Journal: PLoS Biol
Title: ShcA Protects against Epithelial-Mesenchymal Transition through Compartmentalized Inhibition of TGF-β-Induced Smad Activation.
Volume: 13
Issue: 12
Pages: e1002325
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Publication
9199344 | J:326666
First Author: Harmer SL
Year: 1997
Journal: Mol Cell Biol
Title: Shc contains two Grb2 binding sites needed for efficient formation of complexes with SOS in B lymphocytes.
Volume: 17
Issue: 7
Pages: 4087-95
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Publication
7799946 | J:327223
First Author: Sakaue M
Year: 1995
Journal: Mol Cell Biol
Title: A dominant-negative mutant of mSOS1 inhibits insulin-induced Ras activation and reveals Ras-dependent and -independent insulin signaling pathways.
Volume: 15
Issue: 1
Pages: 379-88
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Publication
8776723 | J:327403
First Author: Dey BR
Year: 1996
Journal: Mol Endocrinol
Title: Evidence for the direct interaction of the insulin-like growth factor I receptor with IRS-1, Shc, and Grb10.
Volume: 10
Issue: 6
Pages: 631-41
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Publication
7535773 | J:200359
First Author: VanderKuur J
Year: 1995
Journal: J Biol Chem
Title: Growth hormone-promoted tyrosyl phosphorylation of SHC proteins and SHC association with Grb2.
Volume: 270
Issue: 13
Pages: 7587-93
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Publication
9013573 | J:38680
First Author: Kannan S
Year: 1997
Journal: J Biol Chem
Title: Cripto enhances the tyrosine phosphorylation of Shc and activates mitogen-activated protein kinase (MAPK) in mammary epithelial cells.
Volume: 272
Issue: 6
Pages: 3330-5
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Publication
7657591 | J:156085
First Author: Galisteo ML
Year: 1995
Journal: J Biol Chem
Title: Tyrosine phosphorylation of the c-cbl proto-oncogene protein product and association with epidermal growth factor (EGF) receptor upon EGF stimulation.
Volume: 270
Issue: 35
Pages: 20242-5
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Publication
14576154 | J:87560
First Author: Faisal A
Year: 2004
Journal: J Biol Chem
Title: Non-redundant role of Shc in Erk activation by cytoskeletal reorganization.
Volume: 279
Issue: 5
Pages: 3202-11
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Publication
12486127 | J:81992
First Author: Tong J
Year: 2003
Journal: J Biol Chem
Title: Manipulation of EphB2 regulatory motifs and SH2 binding sites switches MAPK signaling and biological activity.
Volume: 278
Issue: 8
Pages: 6111-9
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Publication
12842895 | J:85667
First Author: Buerger C
Year: 2003
Journal: J Biol Chem
Title: Sequence-specific peptide aptamers, interacting with the intracellular domain of the epidermal growth factor receptor, interfere with Stat3 activation and inhibit the growth of tumor cells.
Volume: 278
Issue: 39
Pages: 37610-21
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Publication
15837797 | J:98081
First Author: Smith WW
Year: 2005
Journal: J Cell Biol
Title: Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity.
Volume: 169
Issue: 2
Pages: 331-9
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Publication
19798056 | J:154710
First Author: Liu NS
Year: 2009
Journal: EMBO J
Title: Participation of Tom1L1 in EGF-stimulated endocytosis of EGF receptor.
Volume: 28
Issue: 22
Pages: 3485-99
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Publication
20685851 | J:182837
First Author: Almeida M
Year: 2010
Journal: Mol Endocrinol
Title: Oxidative stress stimulates apoptosis and activates NF-kappaB in osteoblastic cells via a PKCbeta/p66shc signaling cascade: counter regulation by estrogens or androgens.
Volume: 24
Issue: 10
Pages: 2030-7
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Publication
8610109 | J:32205
First Author: O'Bryan JP
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: A mammalian adaptor protein with conserved Src homology 2 and phosphotyrosine-binding domains is related to Shc and is specifically expressed in the brain.
Volume: 93
Issue: 7
Pages: 2729-34
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Publication
14698816 | J:87700
First Author: Liang H
Year: 2003
Journal: Exp Gerontol
Title: Genetic mouse models of extended lifespan.
Volume: 38
Issue: 11-12
Pages: 1353-64
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Publication
14698815 | J:87701
First Author: Barger JL
Year: 2003
Journal: Exp Gerontol
Title: The retardation of aging by caloric restriction: its significance in the transgenic era.
Volume: 38
Issue: 11-12
Pages: 1343-51
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Publication
29077881 | J:295872
First Author: Costantino S
Year: 2019
Journal: Eur Heart J
Title: Interplay among H3K9-editing enzymes SUV39H1, JMJD2C and SRC-1 drives p66Shc transcription and vascular oxidative stress in obesity.
Volume: 40
Issue: 4
Pages: 383-391
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Publication
30271984 | J:278050
 
First Author: Shahzad K
Year: 2018
Journal: Commun Biol
Title: Activated protein C reverses epigenetically sustained p66Shc expression in plaque-associated macrophages in diabetes.
Volume: 1
Pages: 104
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Publication
12483226 | J:81182
First Author: Holzenberger M
Year: 2003
Journal: Nature
Title: IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice.
Volume: 421
Issue: 6919
Pages: 182-7
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Publication
20697350 | J:164892
First Author: Titz B
Year: 2010
Journal: Oncogene
Title: The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization.
Volume: 29
Issue: 44
Pages: 5895-910
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Publication
17673906 | J:200409
First Author: Lee MK
Year: 2007
Journal: EMBO J
Title: TGF-beta activates Erk MAP kinase signalling through direct phosphorylation of ShcA.
Volume: 26
Issue: 17
Pages: 3957-67
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Publication
17264162 | J:326634
First Author: Uhles S
Year: 2007
Journal: FASEB J
Title: Selective gene activation by spatial segregation of insulin receptor B signaling.
Volume: 21
Issue: 7
Pages: 1609-21
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Publication
8479540 | J:200364
First Author: Rozakis-Adcock M
Year: 1993
Journal: Nature
Title: The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1.
Volume: 363
Issue: 6424
Pages: 83-5
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Publication
8940013 | J:201945
First Author: Chook YM
Year: 1996
Journal: J Biol Chem
Title: The Grb2-mSos1 complex binds phosphopeptides with higher affinity than Grb2.
Volume: 271
Issue: 48
Pages: 30472-8
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Publication
17417601 | J:121631
 
First Author: Xie L
Year: 2007
Journal: Mol Vis
Title: Elevated insulin signaling disrupts the growth and differentiation pattern of the mouse lens.
Volume: 13
Pages: 397-407
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Publication
22039050 | J:315784
First Author: Lin S
Year: 2011
Journal: J Biol Chem
Title: Mutant p53 disrupts role of ShcA protein in balancing Smad protein-dependent and -independent signaling activity of transforming growth factor-β (TGF-β).
Volume: 286
Issue: 51
Pages: 44023-44034
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Publication
22357545 | J:185833
First Author: Fernandes R
Year: 2012
Journal: Biol Reprod
Title: NLRP5 mediates mitochondrial function in mouse oocytes and embryos.
Volume: 86
Issue: 5
Pages: 138, 1-10
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Publication
10809671 | J:62182
First Author: Lai KM
Year: 2000
Journal: Genes Dev
Title: The ShcA phosphotyrosine docking protein sensitizes cardiovascular signaling in the mouse embryo.
Volume: 14
Issue: 9
Pages: 1132-45
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Publication
11163269 | J:66508
First Author: Sakai R
Year: 2000
Journal: Neuron
Title: The mammalian ShcB and ShcC phosphotyrosine docking proteins function in the maturation of sensory and sympathetic neurons.
Volume: 28
Issue: 3
Pages: 819-33
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Publication
23452850 | J:206901
First Author: Findlay GM
Year: 2013
Journal: Cell
Title: Interaction domains of Sos1/Grb2 are finely tuned for cooperative control of embryonic stem cell fate.
Volume: 152
Issue: 5
Pages: 1008-20
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Publication
15121188 | J:91006
First Author: Koponen E
Year: 2004
Journal: Mol Cell Neurosci
Title: Transgenic mice overexpressing the full-length neurotrophin receptor trkB exhibit increased activation of the trkB-PLCgamma pathway, reduced anxiety, and facilitated learning.
Volume: 26
Issue: 1
Pages: 166-81
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Publication
19007875 | J:146582
First Author: Swindell WR
Year: 2009
Journal: Exp Gerontol
Title: Accelerated failure time models provide a useful statistical framework for aging research.
Volume: 44
Issue: 3
Pages: 190-200
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Publication
12808090 | J:83953
First Author: Holgado-Madruga M
Year: 2003
Journal: Mol Cell Biol
Title: Gab1 is an integrator of cell death versus cell survival signals in oxidative stress.
Volume: 23
Issue: 13
Pages: 4471-84
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Publication
11409899 | J:70024
First Author: Kojima T
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Genomic organization of the Shc-related phosphotyrosine adapters and characterization of the full-length Sck/ShcB: specific association of p68-Sck/ShcB with pp135.
Volume: 284
Issue: 4
Pages: 1039-47
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Publication
16400024 | J:104361
First Author: Jiang ST
Year: 2006
Journal: Am J Pathol
Title: Defining a link with autosomal-dominant polycystic kidney disease in mice with congenitally low expression of Pkd1.
Volume: 168
Issue: 1
Pages: 205-20
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Publication
22508726 | J:183920
First Author: Chen J
Year: 2012
Journal: Genes Dev
Title: The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling.
Volume: 26
Issue: 8
Pages: 803-15
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Publication
- | J:103485
     
First Author: Lexicon Genetics Inc
Year: 2005
Journal: MGI Direct Data Submission
Title: NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories
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Publication
15102471 | J:114108
First Author: Papin J
Year: 2004
Journal: Curr Opin Biotechnol
Title: Bioinformatics and cellular signaling.
Volume: 15
Issue: 1
Pages: 78-81
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
22560297 | J:184521
First Author: Koss M
Year: 2012
Journal: Dev Cell
Title: Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.
Volume: 22
Issue: 5
Pages: 913-26
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Gene
106992718 | PYGO2-AS1
Type: gene
Organism: macaque, rhesus
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UniProt Feature
UniProt Feature
Begin: 499
Description: Interaction with SHC1
Type: site
End: 499
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UniProt Feature
UniProt Feature
Begin: 516
Description: Interaction with SHC1
Type: site
End: 516
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UniProt Feature
UniProt Feature
Begin: 515
Description: Interaction with SHC1
Type: site
End: 515
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UniProt Feature
UniProt Feature
Begin: 516
Description: Interaction with SHC1
Type: site
End: 516
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UniProt Feature
UniProt Feature
Begin: 516
Description: Interaction with SHC1
Type: site
End: 516
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Pathway
R-MMU-1250347 | SHC1 events in ERBB4 signaling
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Pathway
R-MMU-180336 | SHC1 events in EGFR signaling
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Pathway
R-MMU-1250196 | SHC1 events in ERBB2 signaling
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Allele
Shc1<em1Smoc> | MGI:7292294
Name: src homology 2 domain-containing transforming protein C1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Shc1<tm1.1Matz> | MGI:7424865
Name: src homology 2 domain-containing transforming protein C1; targeted mutation 1.1, Rachel L Matz
Allele Type: Targeted
Attribute String: Conditional ready
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Protein Coding Gene
MGI:104673 | Ptpn12
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P35831
Organism: Mus musculus/domesticus
Length: 775  
Fragment?: false
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Allele
Tg(EEF1A1-SHC1*)1Ravi | MGI:2384188
Name: transgene insertion 1, Kodi S Ravichandran
Allele Type: Transgenic
Attribute String: Conditional ready, Dominant negative, Inserted expressed sequence, Reporter
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Allele
Tg(EEF1A1-SHC1)1Ravi | MGI:5613976
Name: transgene insertion 1, Kodi S Ravichandran
Allele Type: Transgenic
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter
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