NF-kappa-B inhibitor-like protein 1 (NFKBIL1, also known as IKBL) is a member of the nuclear IkB family. Classical IkB proteins retain NF-kB dimers in the cytoplasm; IkBL belongs to the atypical or nuclear IkB proteins []. It inhibits LPS-induced NF-kB activation and transcription of TNF-alpha and IL-6 [].
