Type |
Details |
Score |
Publication |
First Author: |
Dowling JK |
Year: |
2019 |
Journal: |
J Immunol |
Title: |
The Single Nucleotide Polymorphism Mal-D96N Mice Provide New Insights into Functionality of Mal in TLR Immune Responses. |
Volume: |
202 |
Issue: |
8 |
Pages: |
2384-2396 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sakai J |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Lipopolysaccharide-induced NF-κB nuclear translocation is primarily dependent on MyD88, but TNFα expression requires TRIF and MyD88. |
Volume: |
7 |
Issue: |
1 |
Pages: |
1428 |
|
•
•
•
•
•
|
Publication |
First Author: |
Murugan S |
Year: |
2019 |
Journal: |
J Biol Chem |
Title: |
The neurosteroid pregnenolone promotes degradation of key proteins in the innate immune signaling to suppress inflammation. |
Volume: |
294 |
Issue: |
12 |
Pages: |
4596-4607 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee T |
Year: |
2019 |
Journal: |
Mol Cell Endocrinol |
Title: |
Asprosin impairs insulin secretion in response to glucose and viability through TLR4/JNK-mediated inflammation. |
Volume: |
486 |
|
Pages: |
96-104 |
|
•
•
•
•
•
|
Publication |
First Author: |
Possamai LA |
Year: |
2015 |
Journal: |
Liver Int |
Title: |
The role of intestinal microbiota in murine models of acetaminophen-induced hepatotoxicity. |
Volume: |
35 |
Issue: |
3 |
Pages: |
764-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang X |
Year: |
2019 |
Journal: |
FASEB J |
Title: |
Astaxanthin mitigates subarachnoid hemorrhage injury primarily by increasing sirtuin 1 and inhibiting the Toll-like receptor 4 signaling pathway. |
Volume: |
33 |
Issue: |
1 |
Pages: |
722-737 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gergs U |
Year: |
2019 |
Journal: |
PLoS One |
Title: |
Overexpression of protein phosphatase 5 in the mouse heart: Reduced contractility but increased stress tolerance - Two sides of the same coin? |
Volume: |
14 |
Issue: |
8 |
Pages: |
e0221289 |
|
•
•
•
•
•
|
Publication |
First Author: |
Morioka N |
Year: |
2019 |
Journal: |
J Neurochem |
Title: |
Spinal high-mobility group box-1 induces long-lasting mechanical hypersensitivity through the toll-like receptor 4 and upregulation of interleukin-1β in activated astrocytes. |
Volume: |
150 |
Issue: |
6 |
Pages: |
738-758 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fulham MA |
Year: |
2019 |
Journal: |
Am J Physiol Cell Physiol |
Title: |
Alcohol-induced adipose tissue macrophage phenotypic switching is independent of myeloid Toll-like receptor 4 expression. |
Volume: |
317 |
Issue: |
4 |
Pages: |
C687-C700 |
|
•
•
•
•
•
|
Publication |
First Author: |
Luo L |
Year: |
2020 |
Journal: |
J Leukoc Biol |
Title: |
SCIMP is a universal Toll-like receptor adaptor in macrophages. |
Volume: |
107 |
Issue: |
2 |
Pages: |
251-262 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xie Y |
Year: |
2020 |
Journal: |
J Neurochem |
Title: |
Biglycan regulates neuroinflammation by promoting M1 microglial activation in early brain injury after experimental subarachnoid hemorrhage. |
Volume: |
152 |
Issue: |
3 |
Pages: |
368-380 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lim SG |
Year: |
2020 |
Journal: |
J Immunol |
Title: |
LETMD1 Regulates Phagocytosis and Inflammatory Responses to Lipopolysaccharide via Reactive Oxygen Species Generation and NF-κB Activation in Macrophages. |
Volume: |
204 |
Issue: |
5 |
Pages: |
1299-1309 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schetters STT |
Year: |
2018 |
Journal: |
Front Immunol |
Title: |
Mouse DC-SIGN/CD209a as Target for Antigen Delivery and Adaptive Immunity. |
Volume: |
9 |
|
Pages: |
990 |
|
•
•
•
•
•
|
Publication |
First Author: |
Powell DA |
Year: |
2018 |
Journal: |
Immunohorizons |
Title: |
The Commensal Neisseria musculi Modulates Host Innate Immunity To Promote Oral Colonization. |
Volume: |
2 |
Issue: |
9 |
Pages: |
305-313 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu B |
Year: |
2019 |
Journal: |
J Autoimmun |
Title: |
Interleukin-1 receptor associated kinase (IRAK)-M -mediated type 2 microglia polarization ameliorates the severity of experimental autoimmune encephalomyelitis (EAE). |
Volume: |
102 |
|
Pages: |
77-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim SJ |
Year: |
2019 |
Journal: |
Aging Cell |
Title: |
Endothelial toll-like receptor 4 maintains lung integrity via epigenetic suppression of p16INK4a. |
Volume: |
18 |
Issue: |
3 |
Pages: |
e12914 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hos NJ |
Year: |
2020 |
Journal: |
J Immunol |
Title: |
TRIM21 Is Targeted for Chaperone-Mediated Autophagy during Salmonella Typhimurium Infection. |
Volume: |
205 |
Issue: |
9 |
Pages: |
2456-2467 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kidder K |
Year: |
2020 |
Journal: |
J Immunol |
Title: |
Inflammation Unrestrained by SIRPα Induces Secondary Hemophagocytic Lymphohistiocytosis Independent of IFN-γ. |
Volume: |
205 |
Issue: |
10 |
Pages: |
2821-2833 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen Y |
Year: |
2020 |
Journal: |
Exp Cell Res |
Title: |
Lipopolysaccharide-induced DC-SIGN/TLR4 crosstalk activates NLRP3 inflammasomes via MyD88-independent signaling in gastric epithelial cells. |
Volume: |
396 |
Issue: |
1 |
Pages: |
112292 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mishra MK |
Year: |
2021 |
Journal: |
J Neurosci |
Title: |
Harnessing the Benefits of Neuroinflammation: Generation of Macrophages/Microglia with Prominent Remyelinating Properties. |
Volume: |
41 |
Issue: |
15 |
Pages: |
3366-3385 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yao K |
Year: |
2021 |
Journal: |
Exp Eye Res |
Title: |
Involvement of the NLRC4 inflammasome in promoting retinal ganglion cell death in an acute glaucoma mouse model. |
Volume: |
203 |
|
Pages: |
108388 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yin W |
Year: |
2021 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
CCRL2 promotes antitumor T-cell immunity via amplifying TLR4-mediated immunostimulatory macrophage activation. |
Volume: |
118 |
Issue: |
16 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang H |
Year: |
2020 |
Journal: |
Front Immunol |
Title: |
Hepatic Surgical Stress Promotes Systemic Immunothrombosis That Results in Distant Organ Injury. |
Volume: |
11 |
|
Pages: |
987 |
|
•
•
•
•
•
|
Publication |
First Author: |
Matsusaka K |
Year: |
2021 |
Journal: |
Cancer Res |
Title: |
α1-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages. |
Volume: |
81 |
Issue: |
17 |
Pages: |
4545-4559 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu X |
Year: |
2021 |
Journal: |
Biol Reprod |
Title: |
Pattern recognition receptor-initiated innate immune responses in mouse prostatic epithelial cells‡. |
Volume: |
105 |
Issue: |
1 |
Pages: |
113-127 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fonceca AM |
Year: |
2018 |
Journal: |
Respir Res |
Title: |
Accumulation mode particles and LPS exposure induce TLR-4 dependent and independent inflammatory responses in the lung. |
Volume: |
19 |
Issue: |
1 |
Pages: |
15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chang P |
Year: |
2021 |
Journal: |
PLoS One |
Title: |
Transcriptome profiling reveals new insights into the roles of neuronal nitric oxide synthase on macrophage polarization towards classically activated phenotype. |
Volume: |
16 |
Issue: |
9 |
Pages: |
e0257908 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pradhan K |
Year: |
2021 |
Journal: |
Front Immunol |
Title: |
Development of Exhausted Memory Monocytes and Underlying Mechanisms. |
Volume: |
12 |
|
Pages: |
778830 |
|
•
•
•
•
•
|
Publication |
First Author: |
Oussa NA |
Year: |
2016 |
Journal: |
J Immunol |
Title: |
VEGF Requires the Receptor NRP-1 To Inhibit Lipopolysaccharide-Dependent Dendritic Cell Maturation. |
Volume: |
197 |
Issue: |
10 |
Pages: |
3927-3935 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baptista BJA |
Year: |
2018 |
Journal: |
Front Immunol |
Title: |
TLR9 Signaling Suppresses the Canonical Plasma Cell Differentiation Program in Follicular B Cells. |
Volume: |
9 |
|
Pages: |
2281 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lobenwein D |
Year: |
2015 |
Journal: |
J Am Heart Assoc |
Title: |
Shock Wave Treatment Protects From Neuronal Degeneration via a Toll-Like Receptor 3 Dependent Mechanism: Implications of a First-Ever Causal Treatment for Ischemic Spinal Cord Injury. |
Volume: |
4 |
Issue: |
10 |
Pages: |
e002440 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ahmed D |
Year: |
2021 |
Journal: |
J Immunol |
Title: |
HIF-1α Regulation of Cytokine Production following TLR3 Engagement in Murine Bone Marrow-Derived Macrophages Is Dependent on Viral Nucleic Acid Length and Glucose Availability. |
Volume: |
207 |
Issue: |
11 |
Pages: |
2813-2827 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hu Y |
Year: |
2016 |
Journal: |
Autophagy |
Title: |
Activation of MTOR in pulmonary epithelium promotes LPS-induced acute lung injury. |
Volume: |
12 |
Issue: |
12 |
Pages: |
2286-2299 |
|
•
•
•
•
•
|
Publication |
First Author: |
Peng L |
Year: |
2021 |
Journal: |
Toxins (Basel) |
Title: |
Toxic Shock Syndrome Toxin 1 Induces Immune Response via the Activation of NLRP3 Inflammasome. |
Volume: |
13 |
Issue: |
1 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Takagane K |
Year: |
2022 |
Journal: |
Oncogene |
Title: |
SKAP2 suppresses inflammation-mediated tumorigenesis by regulating SHP-1 and SHP-2. |
Volume: |
41 |
Issue: |
8 |
Pages: |
1087-1099 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sun M |
Year: |
2021 |
Journal: |
Acta Biochim Biophys Sin (Shanghai) |
Title: |
BIG1 mediates sepsis-induced lung injury by modulating lipid raft-dependent macrophage inflammatory responses. |
Volume: |
53 |
Issue: |
8 |
Pages: |
1088-1097 |
|
•
•
•
•
•
|
Publication |
First Author: |
Demel UM |
Year: |
2022 |
Journal: |
Blood Adv |
Title: |
A complex proinflammatory cascade mediates the activation of HSCs upon LPS exposure in vivo. |
Volume: |
6 |
Issue: |
11 |
Pages: |
3513-3528 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gao J |
Year: |
2022 |
Journal: |
Brain Res Bull |
Title: |
Asparagine endopeptidase deletion ameliorates cognitive impairments by inhibiting proinflammatory microglial activation in MPTP mouse model of Parkinson disease. |
Volume: |
178 |
|
Pages: |
120-130 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rokan A |
Year: |
2023 |
Journal: |
Mol Cancer Res |
Title: |
Gut-derived Endotoxin-TLR4 Signaling Drives MYC-Ig Translocation to Promote Lymphoproliferation through c-JUN and STAT3 Activation. |
Volume: |
21 |
Issue: |
2 |
Pages: |
155-169 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shen X |
Year: |
2023 |
Journal: |
J Immunol |
Title: |
cGAS Mediates Inflammation by Polarizing Macrophages to M1 Phenotype via the mTORC1 Pathway. |
Volume: |
210 |
Issue: |
8 |
Pages: |
1098-1107 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zamora-Pineda J |
Year: |
2023 |
Journal: |
J Immunol |
Title: |
Mechanism of TLR4-Mediated Anti-Inflammatory Response Induced by Exopolysaccharide from the Probiotic Bacillus subtilis. |
Volume: |
211 |
Issue: |
8 |
Pages: |
1232-1239 |
|
•
•
•
•
•
|
Publication |
First Author: |
Peng Y |
Year: |
2023 |
Journal: |
Respir Res |
Title: |
SLC38A6 expression in macrophages exacerbates pulmonary inflammation. |
Volume: |
24 |
Issue: |
1 |
Pages: |
33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang J |
Year: |
2023 |
Journal: |
Cell Death Differ |
Title: |
E3 ligase RNF99 negatively regulates TLR-mediated inflammatory immune response via K48-linked ubiquitination of TAB2. |
Volume: |
30 |
Issue: |
4 |
Pages: |
966-978 |
|
•
•
•
•
•
|
Publication |
First Author: |
Campbell E |
Year: |
2024 |
Journal: |
J Immunol |
Title: |
A Lipopolysaccharide-Enriched Cow's Milk Allergy Microbiome Promotes a TLR4-Dependent Proinflammatory Intestinal Immune Response. |
Volume: |
212 |
Issue: |
4 |
Pages: |
702-714 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
943
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
848
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
770
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
897
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
773
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
467
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
467
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Janssens S |
Year: |
2003 |
Journal: |
Mol Cell |
Title: |
Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members. |
Volume: |
11 |
Issue: |
2 |
Pages: |
293-302 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
589
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
358
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
380
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
309
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Yoshida Y |
Year: |
2006 |
Journal: |
Neuron |
Title: |
PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord. |
Volume: |
52 |
Issue: |
5 |
Pages: |
775-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ahuja N |
Year: |
2022 |
Journal: |
Dev Biol |
Title: |
Endothelial Cyp26b1 restrains murine heart valve growth during development. |
Volume: |
486 |
|
Pages: |
81-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bulut Y |
Year: |
2001 |
Journal: |
J Immunol |
Title: |
Cooperation of Toll-like receptor 2 and 6 for cellular activation by soluble tuberculosis factor and Borrelia burgdorferi outer surface protein A lipoprotein: role of Toll-interacting protein and IL-1 receptor signaling molecules in Toll-like receptor 2 signaling. |
Volume: |
167 |
Issue: |
2 |
Pages: |
987-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Leung AKK |
Year: |
2022 |
Journal: |
Atherosclerosis |
Title: |
Modulation of vascular endothelial inflammatory response by proprotein convertase subtilisin-kexin type 9. |
Volume: |
362 |
|
Pages: |
29-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang X |
Year: |
2010 |
Journal: |
J Leukoc Biol |
Title: |
Optimal TLR9 signal converts tolerogenic CD4-8- DCs into immunogenic ones capable of stimulating antitumor immunity via activating CD4+ Th1/Th17 and NK cell responses. |
Volume: |
88 |
Issue: |
2 |
Pages: |
393-403 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim SH |
Year: |
2022 |
Journal: |
Int J Mol Sci |
Title: |
Protein Kinase B2 (PKB2/AKT2) Is Essential for Host Protection in CVB3-Induced Acute Viral Myocarditis. |
Volume: |
23 |
Issue: |
3 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bauer C |
Year: |
2013 |
Journal: |
Am J Respir Cell Mol Biol |
Title: |
Myeloid differentiation factor 88-dependent signaling is critical for acute organic dust-induced airway inflammation in mice. |
Volume: |
48 |
Issue: |
6 |
Pages: |
781-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Watts BA 3rd |
Year: |
2018 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Monophosphoryl lipid A prevents impairment of medullary thick ascending limb [Formula: see text] absorption and improves plasma [Formula: see text] concentration in septic mice. |
Volume: |
315 |
Issue: |
3 |
Pages: |
F711-F725 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fan H |
Year: |
2006 |
Journal: |
Biochim Biophys Acta |
Title: |
Differential regulation of lipopolysaccharide and Gram-positive bacteria induced cytokine and chemokine production in splenocytes by Galphai proteins. |
Volume: |
1763 |
Issue: |
10 |
Pages: |
1051-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Elcombe SE |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Dectin-1 regulates IL-10 production via a MSK1/2 and CREB dependent pathway and promotes the induction of regulatory macrophage markers. |
Volume: |
8 |
Issue: |
3 |
Pages: |
e60086 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hiromura M |
Year: |
2018 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Caveolin-1, a binding protein of CD26, is essential for the anti-inflammatory effects of dipeptidyl peptidase-4 inhibitors on human and mouse macrophages. |
Volume: |
495 |
Issue: |
1 |
Pages: |
223-229 |
|
•
•
•
•
•
|
Publication |
First Author: |
Alves CH |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
Dendritic Cell-Specific Deletion of β-Catenin Results in Fewer Regulatory T-Cells without Exacerbating Autoimmune Collagen-Induced Arthritis. |
Volume: |
10 |
Issue: |
11 |
Pages: |
e0142972 |
|
•
•
•
•
•
|
Publication |
First Author: |
Claes AK |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Salmonella enterica serovar Typhimurium ΔmsbB triggers exacerbated inflammation in Nod2 deficient mice. |
Volume: |
9 |
Issue: |
11 |
Pages: |
e113645 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jeong YJ |
Year: |
2014 |
Journal: |
Immunology |
Title: |
Nod2 and Rip2 contribute to innate immune responses in mouse neutrophils. |
Volume: |
143 |
Issue: |
2 |
Pages: |
269-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kong X |
Year: |
2011 |
Journal: |
Am J Respir Crit Care Med |
Title: |
Enhancing Nrf2 pathway by disruption of Keap1 in myeloid leukocytes protects against sepsis. |
Volume: |
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