Type |
Details |
Score |
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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•
•
•
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•
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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|
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•
•
•
•
•
|
UniProt Feature |
Begin: |
35 |
Description: |
E3 ubiquitin-protein ligase RNF13 |
Type: |
chain |
End: |
381 |
|
•
•
•
•
•
|
Allele |
Name: |
ring finger protein 13; targeted mutation 1.1, Xiang Gao |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
ring finger protein 13; targeted mutation 1, Xiang Gao |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready |
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•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
64
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
96
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Bocock JP |
Year: |
2010 |
Journal: |
Traffic |
Title: |
Nuclear targeting of an endosomal E3 ubiquitin ligase. |
Volume: |
11 |
Issue: |
6 |
Pages: |
756-66 |
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•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Publication |
First Author: |
Park M |
Year: |
2005 |
Journal: |
J Cell Biol |
Title: |
AtRMR1 functions as a cargo receptor for protein trafficking to the protein storage vacuole. |
Volume: |
170 |
Issue: |
5 |
Pages: |
757-67 |
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•
•
•
•
•
|
Publication |
First Author: |
Arshad M |
Year: |
2013 |
Journal: |
J Biol Chem |
Title: |
RNF13, a RING finger protein, mediates endoplasmic reticulum stress-induced apoptosis through the inositol-requiring enzyme (IRE1α)/c-Jun NH2-terminal kinase pathway. |
Volume: |
288 |
Issue: |
12 |
Pages: |
8726-8736 |
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•
•
•
•
•
|
Publication |
First Author: |
Neutzner A |
Year: |
2011 |
Journal: |
J Biol Chem |
Title: |
A systematic search for endoplasmic reticulum (ER) membrane-associated RING finger proteins identifies Nixin/ZNRF4 as a regulator of calnexin stability and ER homeostasis. |
Volume: |
286 |
Issue: |
10 |
Pages: |
8633-8643 |
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•
•
•
•
•
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Protein Domain |
Type: |
Domain |
Description: |
This PA domain is found in ZNRF4 /RNF13/RNF167 from animals and RMR1-6 from Arabidopsis. These proteins contain a C3H2C3 RING finger and some of them are predicted to be membrane-anchored RING finger ubiquitin ligases [, ]. ZNRF4 is an ER-localized RING finger ubiquitin ligase and a regulator of calnexin stability and ER homeostasis []. RNF13 is highly enriched in ER and serves as a critical mediator for facilitating ER stress-induced apoptosis through the activation of the IRE1alpha-TRAF2-JNK signaling pathway []. RMR1 (also known as ReMembR-H2) is a sorting receptor involved in transport of storage proteins to protein storage vacuoles [].The significance of the PA domain to these proteins has not been ascertained. It may be a protein-protein interaction domain. At peptidase active sites, the PA domain may participate in substrate binding and/or promoting conformational changes, which influence the stability and accessibility of the site to substrate. It has been suggested that this domain forms a lid-like structure that covers the active site in active proteases, and is involved in protein recognition in vacuolar sorting receptors []. |
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•
•
•
•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
244
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
131
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
166
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Luo X |
Year: |
2001 |
Journal: |
Trends Biochem Sci |
Title: |
The protease-associated domain: a homology domain associated with multiple classes of proteases. |
Volume: |
26 |
Issue: |
3 |
Pages: |
147-8 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
327
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
352
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
381
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
268
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
347
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
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•
•
•
•
•
|
Publication |
First Author: |
Church DM |
Year: |
2009 |
Journal: |
PLoS Biol |
Title: |
Lineage-specific biology revealed by a finished genome assembly of the mouse. |
Volume: |
7 |
Issue: |
5 |
Pages: |
e1000112 |
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•
•
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•
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