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Search results 101 to 153 out of 153 for Tnfsf14

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Publication

21441458 | J:173115

First Author:	Mouri Y
Year:	2011
Journal:	J Immunol
Title:	Lymphotoxin signal promotes thymic organogenesis by eliciting RANK expression in the embryonic thymic stroma.
Volume:	186
Issue:	9
Pages:	5047-57

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Publication

22357629 | J:183109

First Author:	Wimmer N
Year:	2012
Journal:	J Immunol
Title:	Lymphotoxin β receptor activation on macrophages induces cross-tolerance to TLR4 and TLR9 ligands.
Volume:	188
Issue:	7
Pages:	3426-33

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Publication

12860530 | J:84635

First Author:	Collette Y
Year:	2003
Journal:	Trends Immunol
Title:	A co-evolution perspective of the TNFSF and TNFRSF families in the immune system.
Volume:	24
Issue:	7
Pages:	387-94

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Publication

15170228 | J:90100

First Author:	Hernandez-Valladares M
Year:	2004
Journal:	Mamm Genome
Title:	Confirmation and dissection of QTL controlling resistance to malaria in mice.
Volume:	15
Issue:	5
Pages:	390-8

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Publication

10687308 | J:60454

First Author:	Matsumoto M
Year:	1999
Journal:	J Med Invest
Title:	Role of TNF ligand and receptor family in the lymphoid organogenesis defined by gene targeting.
Volume:	46
Issue:	3-4
Pages:	141-50

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Publication

21419662 | J:169863

First Author:	Powolny-Budnicka I
Year:	2011
Journal:	Immunity
Title:	RelA and RelB transcription factors in distinct thymocyte populations control lymphotoxin-dependent interleukin-17 production in γδ T cells.
Volume:	34
Issue:	3
Pages:	364-74

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Publication

23844157 | J:204300

First Author:	Ge Y
Year:	2013
Journal:	PLoS One
Title:	RNAi screen reveals potentially novel roles of cytokines in myoblast differentiation.
Volume:	8
Issue:	7
Pages:	e68068

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Publication

28096401 | J:240745

First Author:	Hardbower DM
Year:	2017
Journal:	Proc Natl Acad Sci U S A
Title:	Ornithine decarboxylase regulates M1 macrophage activation and mucosal inflammation via histone modifications.
Volume:	114
Issue:	5
Pages:	E751-E760

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Publication

11239407 | J:74923

First Author:	Locksley RM
Year:	2001
Journal:	Cell
Title:	The TNF and TNF receptor superfamilies: integrating mammalian biology.
Volume:	104
Issue:	4
Pages:	487-501

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Publication

- | J:238766

First Author:	Shanghai Model Organisms Center
Year:	2017
Journal:	MGI Direct Data Submission
Title:	Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China

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Publication

- | J:346132

First Author:	The Gene Ontology Consortium
Year:	2016

Title:	Automatic assignment of GO terms using logical inference, based on on inter-ontology links

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Publication

- | J:148605

First Author:	Wellcome Trust Sanger Institute
Year:	2009
Journal:	MGI Direct Data Submission
Title:	Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute

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Publication

- | J:326541

First Author:	Cyagen Biosciences Inc.
Year:	2022

Title:	Cyagen Biosciences Website.

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Publication

- | J:72247

First Author:	DDB, FB, MGI, GOA, ZFIN curators
Year:	2001

Title:	Gene Ontology annotation through association of InterPro records with GO terms

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Publication

- | J:342605

First Author:	GOA curators
Year:	2016

Title:	Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

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Publication

- | J:23000

First Author:	MGD Nomenclature Committee
Year:	1995

Title:	Nomenclature Committee Use

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Publication

21677750 | J:173534

First Author:	Skarnes WC
Year:	2011
Journal:	Nature
Title:	A conditional knockout resource for the genome-wide study of mouse gene function.
Volume:	474
Issue:	7351
Pages:	337-42

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Publication

- | J:60000

First Author:	UniProt-GOA
Year:	2012

Title:	Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping

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Publication

- | J:342587

First Author:	AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year:	2011

Title:	Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

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Publication

- | J:164563

First Author:	The Gene Ontology Consortium
Year:	2010

Title:	Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs

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Publication

21267068 | J:153498

First Author:	Diez-Roux G
Year:	2011
Journal:	PLoS Biol
Title:	A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume:	9
Issue:	1
Pages:	e1000582

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Publication

- | J:57747

First Author:	MGI Genome Annotation Group and UniGene Staff
Year:	2015
Journal:	Database Download
Title:	MGI-UniGene Interconnection Effort

•

Publication

- | J:63103

First Author:	Mouse Genome Database and National Center for Biotechnology Information
Year:	2000
Journal:	Database Release
Title:	Entrez Gene Load

•

Publication

- | J:85324

First Author:	Mouse Genome Informatics Group
Year:	2003
Journal:	Database Procedure
Title:	Automatic Encodes (AutoE) Reference

•

Publication

- | J:53168

First Author:	Bairoch A
Year:	1999
Journal:	Database Release
Title:	SWISS-PROT Annotated protein sequence database

•

Publication

- | J:91388

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations

•

Publication

- | J:155721

First Author:	Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year:	2010
Journal:	Database Download
Title:	Consensus CDS project

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Publication

- | J:155221

First Author:	Mouse Genome Informatics
Year:	2010
Journal:	Database Release
Title:	Protein Ontology Association Load.

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Publication

- | J:90438

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and loading genome assembly coordinates from NCBI annotations

•

Publication

- | J:144086

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform

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Publication

- | J:144087

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform

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Publication

- | J:262123

First Author:	Allen Institute for Brain Science
Year:	2004
Journal:	Allen Institute
Title:	Allen Brain Atlas: mouse riboprobes

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Allele

Tnfsf14<em1Smoc> | MGI:7292905

Name:	tumor necrosis factor (ligand) superfamily, member 14; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type:	Endonuclease-mediated
Attribute String:	Null/knockout

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Strain

MGI:6355297 | C57BL/6J-Tnfsf14<em1Smoc>/Smoc

Attribute String:

coisogenic, mutant strain, endonuclease-mediated mutation

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Allele

Tg(Lck-Tnfsf14)24Yxf | MGI:3849832

Name:	transgene insertion 24, Yang-Xin Fu
Allele Type:	Transgenic
Attribute String:	Inserted expressed sequence

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Strain

MGI:3849843 | C57BL/6-Tg(Lck-Tnfsf14)24Yxf

Attribute String:

transgenic, coisogenic

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Genotype

Symbol:	Tg(Lck-Tnfsf14)24Yxf/?
Background:	C57BL/6-Tg(Lck-Tnfsf14)24Yxf
Zygosity:	ot
Has Mutant Allele:	true

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Publication

20042587 | J:159500

First Author:	Wang Y
Year:	2010
Journal:	J Immunol
Title:	Promoting immune responses by LIGHT in the face of abundant regulatory T cell inhibition.
Volume:	184
Issue:	3
Pages:	1589-95

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Genotype

Symbol:	Tg(Lck-Tnfsf14)24Yxf/? Tnfrsf14/Tnfrsf14
Background:	involves: 129P2/OlaHsd * C57BL/6
Zygosity:	cx
Has Mutant Allele:	true

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Publication

27982078 | J:243454

First Author:	Sibilano R
Year:	2016
Journal:	Nat Commun
Title:	A TNFRSF14-FcɛRI-mast cell pathway contributes to development of multiple features of asthma pathology in mice.
Volume:	7

Pages:	13696

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Publication

16934497 | J:113447

First Author:	Lee Y
Year:	2006
Journal:	Immunity
Title:	Recruitment and activation of naive T cells in the islets by lymphotoxin beta receptor-dependent tertiary lymphoid structure.
Volume:	25
Issue:	3
Pages:	499-509

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Strain

MGI:3850009 | B6.Cg-Ltbr<tm1Kpf> Tg(Lck-Tnfsf14)24Yxf

Attribute String:

targeted mutation, transgenic, congenic

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Publication

15067315 | J:128976

First Author:	Wang J
Year:	2004
Journal:	J Clin Invest
Title:	Dysregulated LIGHT expression on T cells mediates intestinal inflammation and contributes to IgA nephropathy.
Volume:	113
Issue:	6
Pages:	826-35

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Genotype

Symbol:	Ltbr/Ltbr Tg(Lck-Tnfsf14)24Yxf/?
Background:	B6.Cg-Ltbr Tg(Lck-Tnfsf14)24Yxf
Zygosity:	cx
Has Mutant Allele:	true

•

Publication

22325083 | -

First Author:	Chen MH
Year:	2012
Journal:	Clin Exp Rheumatol
Title:	Overexpression of decoy receptor 3 in synovial tissues of inflammatory arthritis.
Volume:	30
Issue:	2
Pages:	171-7

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Publication

22626963 | -

First Author:	Hung SC
Year:	2012
Journal:	Clin J Am Soc Nephrol
Title:	Decoy receptor 3, a novel inflammatory marker, and mortality in hemodialysis patients.
Volume:	7
Issue:	8
Pages:	1257-65

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Publication

21295012 | -

First Author:	Lin WW
Year:	2011
Journal:	Biochem Pharmacol
Title:	Decoy receptor 3: a pleiotropic immunomodulator and biomarker for inflammatory diseases, autoimmune diseases and cancer.
Volume:	81
Issue:	7
Pages:	838-47

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Publication

18201904 | -

First Author:	Inoue Y
Year:	2008
Journal:	Fish Shellfish Immunol
Title:	Molecular cloning and preliminary expression analysis of banded dogfish (Triakis scyllia) TNF decoy receptor 3 (TNFRSF6B).
Volume:	24
Issue:	3
Pages:	360-5

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Protein Domain

IPR034023 | TNFRSF6B_N

Type:

Domain

Description:

Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) is also known as decoy receptor 3 (DcR3), M68, or TR6. This protein is a soluble receptor secreted by cells, that does not contain a death domain and cytoplasmic domain. It acts as a decoy receptor that competes with death receptors for ligand binding. It is a pleiotropic immunomodulator and biomarker for inflammatory diseases, autoimmune diseases, and cancer []. Over-expression of this gene has been noted in several cancers, including pancreatic carcinoma, and gastrointestinal tract tumors. It can neutralize the biological effects of three tumor necrosis factor superfamily (TNFSF) members: TNFSF6 (Fas ligand/FasL/CD95L) and TNFSF14 (LIGHT) which are both involved in apoptosis and inflammation, and TNFSF15 (TNF-like molecule 1A/TL1A), which is a T cell co-stimulator and involved in gut inflammation []. DcR3 is a novel inflammatory marker; higher DcR3 levels strongly correlate with inflammation and independently predict cardiovascular and all-cause mortality in chronic kidney disease (CKD) patients on hemodialysis []. Increased synovial inflammatory cells infiltration in rheumatoid arthritis and ankylosing spondylitis is also associated with the elevated DcR3 expression []. In cartilaginous fish, mRNA expression of DcR3 in the thymus and leydig, which are the representative lymphoid tissues of elasmobranchs, suggests that DcR3 may act as a modulator in the immune system. Interestingly, in banded dogfish (Triakis scyllia), DcR3 mRNA is strongly expressed in the gill, compared with human expression in the normal lung; both are respiratory organs, suggesting potential relevance of DcR3 to respiratory function [].This entry represents the N-terminal domain of TNFRSF6B. TNF-receptors are modular proteins. The N-terminal extracellular part contains a cysteine-rich region responsible for ligand-binding. This region is composed of small modules of about 40 residues containing 6 conserved cysteines; the number and type of modules can vary in different members of the family [, , ].

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Publication

30445013 | J:294541

First Author:	Elßner C
Year:	2019
Journal:	Gastroenterology
Title:	Nuclear Translocation of RELB Is Increased in Diseased Human Liver and Promotes Ductular Reaction and Biliary Fibrosis in Mice.
Volume:	156
Issue:	4
Pages:	1190-1205.e14

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Publication

9538693 | -

First Author:	Naismith JH
Year:	1998
Journal:	Trends Biochem Sci
Title:	Modularity in the TNF-receptor family.
Volume:	23
Issue:	2
Pages:	74-9

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Publication

11796220 | -

First Author:	Bodmer JL
Year:	2002
Journal:	Trends Biochem Sci
Title:	The molecular architecture of the TNF superfamily.
Volume:	27
Issue:	1
Pages:	19-26

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Publication

8387891 | -

First Author:	Banner DW
Year:	1993
Journal:	Cell
Title:	Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation.
Volume:	73
Issue:	3
Pages:	431-45

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