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Search results 1 to 100 out of 1339 for Nrg1

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Type Details Score
Gene
3084 | NRG1
Type: gene
Organism: human
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Gene
796461 | nrg1
Type: gene
Organism: zebrafish
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Gene
696275 | NRG1
Type: gene
Organism: macaque, rhesus
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Gene
100496613 | nrg1
Type: gene
Organism: frog, western clawed
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Gene
112400 | Nrg1
Type: gene
Organism: rat
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Gene
464102 | NRG1
Type: gene
Organism: chimpanzee
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Gene
482861 | NRG1
Type: gene
Organism: dog, domestic
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Gene
281361 | NRG1
Type: gene
Organism: cattle
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Gene
373906 | NRG1
Type: gene
Organism: chicken
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Protein Domain
IPR018250 | NRG1
Type: Family
Description: Neuregulins are a sub-family of EGF-like molecules that have been shown to play multiple essential roles in vertebrate embryogenesis including: cardiac development, Schwann cell and oligodendrocyte differentiation, some aspects of neuronal development, as well as the formation of neuromuscular synapses [, ]. Included in the family are heregulin; neu differentiation factor; acetylcholine receptor synthesis stimulator; glial growth factor; and sensory and motor-neuron derived factor []. Multiple family members are generated by alternate splicing or by use of several cell type-specific transcription initiation sites. In general, they bind to and activate the erbB family of receptor tyrosine kinases (erbB2 (HER2), erbB3 (HER3), and erbB4 (HER4)), functioning both as heterodimers and homodimers.The transmembrane forms of neuregulin 1 (NRG1) are present within synaptic vesicles, including those containing glutamate []. After exocytosis, NRG1 is in the presynaptic membrane, where the ectodomain of NRG1 may be cleaved off. The ectodomain then migrates across the synaptic cleft and binds to and activates a member of the EGF-receptor family on the postsynaptic membrane. This has been shown to increase the expression of certain glutamate-receptor subunits. NRG1 appears to signal for glutamate-receptor subunit expression, localisation, and /or phosphorylation facilitating subsequent glutamate transmission. The NRG1 gene has been identified as a potential gene determining susceptibility to schizophrenia by a combination of genetic linkage and association approaches [].
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Protein Coding Gene
MGI:96083 | Nrg1
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
100856811 | NRG1-IT1
Type: gene
Organism: human
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Gene
100874286 | NRG1-IT3
Type: gene
Organism: human
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Publication
12145742 | J:81106
First Author: Stefansson H
Year: 2002
Journal: Am J Hum Genet
Title: Neuregulin 1 and susceptibility to schizophrenia.
Volume: 71
Issue: 4
Pages: 877-92
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Publication
9892702 | J:52282
First Author: Vartanian T
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Failure of spinal cord oligodendrocyte development in mice lacking neuregulin.
Volume: 96
Issue: 2
Pages: 731-5
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GXD Expression
GXD Expression
 
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450868
Age: embryonic day 12.5
Image: Nrg1 - E12.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Label: Nrg1 - E12.5
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450868
Age: embryonic day 14.5
Image: Nrg1 - E14.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Label: Nrg1 - E14.5
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450868
Age: embryonic day 16.5
Image: Nrg1 - E16.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Label: Nrg1 - E16.5
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271220
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450868
Age: embryonic day 12.5
Image: Nrg1 - E12.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Label: Nrg1 - E12.5
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450868
Age: embryonic day 14.5
Image: Nrg1 - E14.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Label: Nrg1 - E14.5
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450868
Age: embryonic day 16.5
Image: Nrg1 - E16.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Label: Nrg1 - E16.5
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754320
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450868
Age: embryonic day 12.5
Image: Nrg1 - E12.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Label: Nrg1 - E12.5
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754322
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450868
Age: embryonic day 14.5
Image: Nrg1 - E14.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Label: Nrg1 - E14.5
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754324
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450868
Age: embryonic day 16.5
Image: Nrg1 - E16.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Label: Nrg1 - E16.5
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1753720
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450868
Age: embryonic day 12.5
Image: Nrg1 - E12.5
Note: There is moderate staining in the mantle zone of the PVH nucleus. Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the VMH and ARH nuclei, the AVH and anterior and posterior IDs.
Specimen Label: Nrg1 - E12.5
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1753722
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450868
Age: embryonic day 14.5
Image: Nrg1 - E14.5
Note: There is moderate staining in the mantle zone of the PVH nucleus. Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the VMH and ARH nuclei, the AVH and anterior and posterior IDs.
Specimen Label: Nrg1 - E14.5
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1753724
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450868
Age: embryonic day 16.5
Image: Nrg1 - E16.5
Note: There is moderate staining in the mantle zone of the PVH nucleus. Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the SCH, DMH, VMH and ARH nuclei, the AVH, the DAH and the PH.
Specimen Label: Nrg1 - E16.5
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1691319
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450868
Age: embryonic day 11.5
Image: Nrg1 - E11.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex and the ganglionic eminences.
Specimen Label: Nrg1 - E11.5
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271820
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450868
Age: embryonic day 12.5
Image: Nrg1 - E12.5
Note: There is weak staining in the mantle zone of the mam zone. Staining is either absent or ubiquitous in the mantle zone of the premam and supramam zones and the TT.
Specimen Label: Nrg1 - E12.5
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450868
Age: embryonic day 14.5
Image: Nrg1 - E14.5
Note: Staining is either absent or ubiquitous in the mantle zone of the premam, mam and supramam zones and the TT.
Specimen Label: Nrg1 - E14.5
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271824
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450868
Age: embryonic day 16.5
Image: Nrg1 - E16.5
Note: There is weak staining in the mantle zone of the mam zone. Staining is either absent or ubiquitous in the mantle zone of the premam and supramam zones.
Specimen Label: Nrg1 - E16.5
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1690819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450868
Age: embryonic day 11.5
Image: Nrg1 - E11.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus, the prethalamus, dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH, the anterior and posterior IDs, the premam, mam and supramam zones and the TT.
Specimen Label: Nrg1 - E11.5
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1753920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450868
Age: embryonic day 12.5
Image: Nrg1 - E12.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
Specimen Label: Nrg1 - E12.5
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1753922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450868
Age: embryonic day 14.5
Image: Nrg1 - E14.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
Specimen Label: Nrg1 - E14.5
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1753924
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450868
Age: embryonic day 16.5
Image: Nrg1 - E16.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, SCH, DMH, VMH and ARH nuclei, the AVH, the DAH and the PH.
Specimen Label: Nrg1 - E16.5
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691119
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450868
Age: embryonic day 11.5
Image: Nrg1 - E11.5
Note: There is weak staining in the postmitotic neurons in the intermediate zone and cortical plate of the cerebral cortex and in the mantle zone of the ganglionic eminences.
Specimen Label: Nrg1 - E11.5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450868
Age: embryonic day 12.5
Image: Nrg1 - E12.5
Note: There is moderate staining in the ventricular zone of the cerebral cortex.
Specimen Label: Nrg1 - E12.5
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450868
Age: embryonic day 14.5
Image: Nrg1 - E14.5
Note: There is strong staining in the ventricular zone of the cerebral cortex.
Specimen Label: Nrg1 - E14.5
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1754724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450868
Age: embryonic day 16.5
Image: Nrg1 - E16.5
Note: There is very strong staining in the ventricular zone of the cerebral cortex.
Specimen Label: Nrg1 - E16.5
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271020
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450868
Age: embryonic day 12.5
Image: Nrg1 - E12.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones and the TT.
Specimen Label: Nrg1 - E12.5
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271022
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450868
Age: embryonic day 14.5
Image: Nrg1 - E14.5
Note: There is weak staining in the ventricular zone of the mam zone. Staining is either absent or ubiquitous in the ventricular zone of the premam and supramam zones and the TT.
Specimen Label: Nrg1 - E14.5
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450868
Age: embryonic day 16.5
Image: Nrg1 - E16.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones.
Specimen Label: Nrg1 - E16.5
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3266520
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450868
Age: embryonic day 12.5
Image: Nrg1 - E12.5
Note: There is moderate staining in the ventricular zone of the ganglionic eminences. Staining is either absent or ubiquitous in the mantle zone of the ganglionic eminences.
Specimen Label: Nrg1 - E12.5
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3266522
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450868
Age: embryonic day 14.5
Image: Nrg1 - E14.5
Note: There is strong staining in the ventricular zone of the ganglionic eminences. Staining is either absent or ubiquitous in the mantle zone of the ganglionic eminences.
Specimen Label: Nrg1 - E14.5
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3266524
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450868
Age: embryonic day 16.5
Image: Nrg1 - E16.5
Note: Staining is either absent or ubiquitous in the ventricular and mantle zones of the ganglionic eminences.
Specimen Label: Nrg1 - E16.5
Specimen Num: 8
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•
GXD Expression
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690619
Pattern: Non-Uniform
Stage: TS19
Assay Id: MGI:4450868
Age: embryonic day 11.5
Image: Nrg1 - E11.5
Note: Staining is moderate in the MZ of the prethalamus & weak in the mam zone. Staining is either absent or ubiquitous in the MZ of the dorsal thalamus, dorsal & ventral POAs, PVH, VMH & ARH nuclei, AVH, anterior & posterior IDs, premam & supramam zones & TT.
Specimen Label: Nrg1 - E11.5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754120
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450868
Age: embryonic day 12.5
Image: Nrg1 - E12.5
Note: There is moderate staining in the mantle zone of the prethalamus. Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus.
Specimen Label: Nrg1 - E12.5
Detected: true
Specimen Num: 6
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•
GXD Expression
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754122
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450868
Age: embryonic day 14.5
Image: Nrg1 - E14.5
Note: There is moderate staining in the mantle zone of the dorsal thalamus and weak staining in the prethalamus.
Specimen Label: Nrg1 - E14.5
Detected: true
Specimen Num: 7
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•
GXD Expression
GXD Expression
 
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450868
Age: embryonic day 16.5
Image: Nrg1 - E16.5
Note: Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus and prethalamus.
Specimen Label: Nrg1 - E16.5
Specimen Num: 8
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Publication
34246770 | J:310654
 
First Author: Navarro-Gonzalez C
Year: 2021
Journal: Neurobiol Dis
Title: Nrg1 haploinsufficiency alters inhibitory cortical circuits.
Volume: 157
Pages: 105442
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Publication
19458253 | J:149996
First Author: Tao Y
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Erbin regulates NRG1 signaling and myelination.
Volume: 106
Issue: 23
Pages: 9477-82
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Publication
- | J:81760
     
First Author: Falls D
Year: 2003
Journal: Personal Communication
Title: Physical mapping of Nrg1 to mouse Chromosome 8
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Publication
37846569 | J:353335
First Author: Grego-Bessa J
Year: 2023
Journal: Circ Res
Title: Nrg1 Regulates Cardiomyocyte Migration and Cell Cycle in Ventricular Development.
Volume: 133
Issue: 11
Pages: 927-943
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Publication
30931926 | J:273263
First Author: Fledrich R
Year: 2019
Journal: Nat Commun
Title: NRG1 type I dependent autoparacrine stimulation of Schwann cells in onion bulbs of peripheral neuropathies.
Volume: 10
Issue: 1
Pages: 1467
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Publication
9804837 | -
First Author: Schroering A
Year: 1998
Journal: J Biol Chem
Title: Sensory and motor neuron-derived factor is a transmembrane heregulin that is expressed on the plasma membrane with the active domain exposed to the extracellular environment.
Volume: 273
Issue: 46
Pages: 30643-50
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Publication
9208852 | -
First Author: Burden S
Year: 1997
Journal: Neuron
Title: Neuregulins and their receptors: a versatile signaling module in organogenesis and oncogenesis.
Volume: 18
Issue: 6
Pages: 847-55
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Publication
21322058 | J:169756
First Author: Arthur-Farraj P
Year: 2011
Journal: Glia
Title: Mouse schwann cells need both NRG1 and cyclic AMP to myelinate.
Volume: 59
Issue: 5
Pages: 720-33
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Publication
22052506 | J:262505
First Author: Velanac V
Year: 2012
Journal: Glia
Title: Bace1 processing of NRG1 type III produces a myelin-inducing signal but is not essential for the stimulation of myelination.
Volume: 60
Issue: 2
Pages: 203-17
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Publication
20393464 | J:159459
First Author: Fazzari P
Year: 2010
Journal: Nature
Title: Control of cortical GABA circuitry development by Nrg1 and ErbB4 signalling.
Volume: 464
Issue: 7293
Pages: 1376-80
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Protein
Q810X0
Organism: Mus musculus/domesticus
Length: 76  
Fragment?: true
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Publication
38918041 | J:350240
 
First Author: Rodríguez-Prieto Á
Year: 2024
Journal: Life Sci Alliance
Title: Nrg1 intracellular signaling regulates the development of interhemispheric callosal axons in mice.
Volume: 7
Issue: 9
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Publication
28275713 | J:255850
 
First Author: Zhong C
Year: 2017
Journal: eNeuro
Title: Axonal Type III Nrg1 Controls Glutamate Synapse Formation and GluA2 Trafficking in Hippocampal-Accumbens Connections.
Volume: 4
Issue: 1
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Protein
Q6DR99
Organism: Mus musculus/domesticus
Length: 700  
Fragment?: false
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Protein
A0A140LHD8
Organism: Mus musculus/domesticus
Length: 300  
Fragment?: true
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Protein
A0A5F8MPT8
Organism: Mus musculus/domesticus
Length: 695  
Fragment?: false
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Protein
A0A5F8MQ49
Organism: Mus musculus/domesticus
Length: 285  
Fragment?: false
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Protein
A0A140LIG9
Organism: Mus musculus/domesticus
Length: 483  
Fragment?: false
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Protein
Q3TD94
Organism: Mus musculus/domesticus
Length: 311  
Fragment?: false
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Protein
Q3URY7
Organism: Mus musculus/domesticus
Length: 483  
Fragment?: false
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Publication
24650175 | J:214137
First Author: Kawashima I
Year: 2014
Journal: Mol Endocrinol
Title: Targeted disruption of Nrg1 in granulosa cells alters the temporal progression of oocyte maturation.
Volume: 28
Issue: 5
Pages: 706-21
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Publication
29964074 | J:321893
 
First Author: Clarke DJ
Year: 2019
Journal: Prog Neuropsychopharmacol Biol Psychiatry
Title: Nrg1 deficiency modulates the behavioural effects of prenatal stress in mice.
Volume: 88
Pages: 86-95
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Publication
27521758 | J:330103
 
First Author: Clarke DJ
Year: 2017
Journal: Prog Neuropsychopharmacol Biol Psychiatry
Title: Endocannabinoid dysregulation in cognitive and stress-related brain regions in the Nrg1 mouse model of schizophrenia.
Volume: 72
Pages: 9-15
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Publication
31499092 | J:291390
 
First Author: Zieba J
Year: 2020
Journal: Behav Brain Res
Title: Behavioural effects of high fat diet in adult Nrg1 type III transgenic mice.
Volume: 377
Pages: 112217
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Publication
30040984 | J:267191
 
First Author: Gregoire EP
Year: 2018
Journal: Mol Cell Endocrinol
Title: NRG1 signalling regulates the establishment of Sertoli cell stock in the mouse testis.
Volume: 478
Pages: 17-31
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Protein
A0A5F8MPA3
Organism: Mus musculus/domesticus
Length: 604  
Fragment?: false
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Protein
A0A5F8MP73
Organism: Mus musculus/domesticus
Length: 433  
Fragment?: false
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Protein
A0A140LJ88
Organism: Mus musculus/domesticus
Length: 663  
Fragment?: false
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Protein
A0A140LJC1
Organism: Mus musculus/domesticus
Length: 640  
Fragment?: false
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Protein
A0A140LIP8
Organism: Mus musculus/domesticus
Length: 637  
Fragment?: false
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Protein
A0A5F8MPU1
Organism: Mus musculus/domesticus
Length: 485  
Fragment?: false
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Protein
A0A5F8MPJ0
Organism: Mus musculus/domesticus
Length: 603  
Fragment?: false
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Protein
A0A140LHZ9
Organism: Mus musculus/domesticus
Length: 858  
Fragment?: false
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Protein
A0A140LHG5
Organism: Mus musculus/domesticus
Length: 459  
Fragment?: false
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Protein
A0A140LHN1
Organism: Mus musculus/domesticus
Length: 423  
Fragment?: false
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Protein
A0A140LIK5
Organism: Mus musculus/domesticus
Length: 462  
Fragment?: false
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Protein
Q6DR98
Organism: Mus musculus/domesticus
Length: 645  
Fragment?: false
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Publication
18626010 | J:138187
First Author: Dejaegere T
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Deficiency of Aph1B/C-gamma-secretase disturbs Nrg1 cleavage and sensorimotor gating that can be reversed with antipsychotic treatment.
Volume: 105
Issue: 28
Pages: 9775-80
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Publication
29743679 | J:262042
First Author: Del Monte-Nieto G
Year: 2018
Journal: Nature
Title: Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation.
Volume: 557
Issue: 7705
Pages: 439-445
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Publication
21949864 | J:177871
First Author: Canetta SE
Year: 2011
Journal: PLoS One
Title: Type III Nrg1 back signaling enhances functional TRPV1 along sensory axons contributing to basal and inflammatory thermal pain sensation.
Volume: 6
Issue: 9
Pages: e25108
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Publication
21949880 | J:175524
First Author: Chen B
Year: 2011
Journal: PLoS One
Title: An ENU-induced mutation of Nrg1 causes dilated pupils and a reduction in muscarinic receptors in the sphincter pupillae.
Volume: 6
Issue: 9
Pages: e25176
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Publication
23447498 | J:314831
 
First Author: Spencer JR
Year: 2013
Journal: Front Cell Neurosci
Title: Novel molecular changes induced by Nrg1 hypomorphism and Nrg1-cannabinoid interaction in adolescence: a hippocampal proteomic study in mice.
Volume: 7
Pages: 15
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Protein
A0A140LIJ3
Organism: Mus musculus/domesticus
Length: 472  
Fragment?: true
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Protein
A0A5F8MPD1
Organism: Mus musculus/domesticus
Length: 206  
Fragment?: true
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Protein
A0A5F8MPS5
Organism: Mus musculus/domesticus
Length: 420  
Fragment?: false
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Protein
A0A5F8MPN0
Organism: Mus musculus/domesticus
Length: 241  
Fragment?: false
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Protein
A0A5F8MPL7
Organism: Mus musculus/domesticus
Length: 324  
Fragment?: true
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Protein
A0A5F8MQ03
Organism: Mus musculus/domesticus
Length: 247  
Fragment?: false
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Publication
26217011 | J:228225
First Author: Parra LM
Year: 2015
Journal: Mol Cell Biol
Title: Distinct Intracellular Domain Substrate Modifications Selectively Regulate Ectodomain Cleavage of NRG1 or CD44.
Volume: 35
Issue: 19
Pages: 3381-95
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GXD Expression
GXD Expression
   
Probe: MGI:6179311
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190957
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Nrg1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6179311
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190957
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Nrg1
Detected: true
Specimen Num: 2
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom