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Search results 301 to 400 out of 447 for Map2k2

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Type Details Score
Publication
21527500 | J:278979
First Author: Yamashita S
Year: 2011
Journal: Mol Endocrinol
Title: The Leydig cell MEK/ERK pathway is critical for maintaining a functional population of adult Leydig cells and for fertility.
Volume: 25
Issue: 7
Pages: 1211-22
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21699731 | J:327220
 
First Author: Fritz JM
Year: 2011
Journal: Mol Cancer
Title: Stimulation of neoplastic mouse lung cell proliferation by alveolar macrophage-derived, insulin-like growth factor-1 can be blocked by inhibiting MEK and PI3K activation.
Volume: 10
Pages: 76
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Publication
20179103 | J:175345
First Author: Pan CQ
Year: 2010
Journal: J Cell Sci
Title: Active Mek2 as a regulatory scaffold that promotes Pin1 binding to BPGAP1 to suppress BPGAP1-induced acute Erk activation and cell migration.
Volume: 123
Issue: Pt 6
Pages: 903-16
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Publication
7592946 | J:30272
First Author: Pagès G
Year: 1995
Journal: J Biol Chem
Title: The mouse p44 mitogen-activated protein kinase (extracellular signal-regulated kinase 1) gene. Genomic organization and structure of the 5'-flanking regulatory region.
Volume: 270
Issue: 45
Pages: 26986-92
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Publication
19144315 | J:143721
First Author: Conche C
Year: 2009
Journal: Immunity
Title: T cell adhesion primes antigen receptor-induced calcium responses through a transient rise in adenosine 3',5'-cyclic monophosphate.
Volume: 30
Issue: 1
Pages: 33-43
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Publication
28746311 | J:252615
First Author: Choi J
Year: 2017
Journal: Nature
Title: Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells.
Volume: 548
Issue: 7666
Pages: 219-223
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Publication
24746703 | J:210622
First Author: Chen T
Year: 2014
Journal: Cancer Cell
Title: Small GTPase RBJ mediates nuclear entrapment of MEK1/MEK2 in tumor progression.
Volume: 25
Issue: 5
Pages: 682-96
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Publication
26208884 | J:278579
First Author: Bouhamdan M
Year: 2015
Journal: Cell Signal
Title: MEK1 dependent and independent ERK activation regulates IL-10 and IL-12 production in bone marrow derived macrophages.
Volume: 27
Issue: 10
Pages: 2068-76
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Publication
24045785 | J:317231
 
First Author: Whittington RA
Year: 2013
Journal: Sci Rep
Title: Anesthesia-induced hypothermia mediates decreased ARC gene and protein expression through ERK/MAPK inactivation.
Volume: 3
Pages: 1388
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Publication
27913296 | J:303014
First Author: Dungan CM
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Regulation of skeletal muscle insulin-stimulated signaling through the MEK-REDD1-mTOR axis.
Volume: 482
Issue: 4
Pages: 1067-1072
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Publication
17885219 | J:142788
First Author: Jagavelu K
Year: 2007
Journal: Circ Res
Title: Systemic deficiency of the MAP kinase-activated protein kinase 2 reduces atherosclerosis in hypercholesterolemic mice.
Volume: 101
Issue: 11
Pages: 1104-12
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Publication
27152455 | J:258208
First Author: Duhamel S
Year: 2016
Journal: Cell Cycle
Title: Deregulated ERK1/2 MAP kinase signaling promotes aneuploidy by a Fbxw7β-Aurora A pathway.
Volume: 15
Issue: 12
Pages: 1631-42
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Publication
25134715 | J:272427
 
First Author: Eales KL
Year: 2014
Journal: Nat Commun
Title: The MK2/3 cascade regulates AMPAR trafficking and cognitive flexibility.
Volume: 5
Pages: 4701
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Publication
19808857 | J:155222
First Author: Johansen C
Year: 2009
Journal: Carcinogenesis
Title: MK2 regulates the early stages of skin tumor promotion.
Volume: 30
Issue: 12
Pages: 2100-8
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Publication
17576778 | J:125870
First Author: Gorska MM
Year: 2007
Journal: J Exp Med
Title: MK2 controls the level of negative feedback in the NF-kappaB pathway and is essential for vascular permeability and airway inflammation.
Volume: 204
Issue: 7
Pages: 1637-52
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Publication
14556008 | J:85793
First Author: Bomar JM
Year: 2003
Journal: Nat Genet
Title: Mutations in a novel gene encoding a CRAL-TRIO domain cause human Cayman ataxia and ataxia/dystonia in the jittery mouse.
Volume: 35
Issue: 3
Pages: 264-9
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Publication
19565474 | J:180564
First Author: Yao Z
Year: 2009
Journal: Biofactors
Title: The ERK signaling cascade--views from different subcellular compartments.
Volume: 35
Issue: 5
Pages: 407-16
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8385802 | J:29891
First Author: Lange-Carter CA
Year: 1993
Journal: Science
Title: A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf.
Volume: 260
Issue: 5106
Pages: 315-9
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Publication
16508014 | J:106919
First Author: Hitti E
Year: 2006
Journal: Mol Cell Biol
Title: Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich element.
Volume: 26
Issue: 6
Pages: 2399-407
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Publication
35021072 | J:320530
First Author: Houde N
Year: 2022
Journal: Cell Rep
Title: Fine-tuning of MEK signaling is pivotal for limiting B and T cell activation.
Volume: 38
Issue: 2
Pages: 110223
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Publication
34386488 | J:311510
 
First Author: Beuret L
Year: 2021
Journal: Front Cell Dev Biol
Title: Mek1 and Mek2 Functional Redundancy in Erythropoiesis.
Volume: 9
Pages: 639022
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Publication
35122074 | J:322704
First Author: Falcomatà C
Year: 2022
Journal: Nat Cancer
Title: Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment.
Volume: 3
Issue: 3
Pages: 318-336
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Publication
24239348 | J:203686
First Author: Morandell S
Year: 2013
Journal: Cell Rep
Title: A reversible gene-targeting strategy identifies synthetic lethal interactions between MK2 and p53 in the DNA damage response in vivo.
Volume: 5
Issue: 4
Pages: 868-77
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Publication
20375303 | J:161009
First Author: Gais P
Year: 2010
Journal: J Immunol
Title: TRIF signaling stimulates translation of TNF-alpha mRNA via prolonged activation of MK2.
Volume: 184
Issue: 10
Pages: 5842-8
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Publication
8388392 | J:31929
First Author: Zheng CF
Year: 1993
Journal: J Biol Chem
Title: Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2.
Volume: 268
Issue: 15
Pages: 11435-9
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Publication
22393900 | J:184475
First Author: Wang X
Year: 2012
Journal: J Neurochem
Title: Activation of the extracellular signal-regulated kinase pathway contributes to the behavioral deficit of fragile x-syndrome.
Volume: 121
Issue: 4
Pages: 672-9
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Publication
16423921 | J:111093
First Author: Tietz AB
Year: 2006
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Gene deletion of MK2 inhibits TNF-alpha and IL-6 and protects against cerulein-induced pancreatitis.
Volume: 290
Issue: 6
Pages: G1298-306
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Publication
9149902 | J:40857
First Author: Alessandrini A
Year: 1997
Journal: Cell Growth Differ
Title: Differential expression of MEK1 and MEK2 during mouse development.
Volume: 8
Issue: 5
Pages: 505-11
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Publication
16880206 | J:116928
First Author: Tan AH
Year: 2006
Journal: J Biol Chem
Title: Regulation of mouse inducible costimulator (ICOS) expression by Fyn-NFATc2 and ERK signaling in T cells.
Volume: 281
Issue: 39
Pages: 28666-78
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Publication
19240800 | J:145960
First Author: Damarla M
Year: 2009
Journal: PLoS One
Title: Mitogen activated protein kinase activated protein kinase 2 regulates actin polymerization and vascular leak in ventilator associated lung injury.
Volume: 4
Issue: 2
Pages: e4600
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Publication
19628790 | J:169976
First Author: van Wijk B
Year: 2009
Journal: Circ Res
Title: Epicardium and myocardium separate from a common precursor pool by crosstalk between bone morphogenetic protein- and fibroblast growth factor-signaling pathways.
Volume: 105
Issue: 5
Pages: 431-41
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Publication
15118098 | J:89950
First Author: Vomastek T
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Modular construction of a signaling scaffold: MORG1 interacts with components of the ERK cascade and links ERK signaling to specific agonists.
Volume: 101
Issue: 18
Pages: 6981-6
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Publication
17030606 | J:117668
First Author: Ronkina N
Year: 2007
Journal: Mol Cell Biol
Title: The mitogen-activated protein kinase (MAPK)-activated protein kinases MK2 and MK3 cooperate in stimulation of tumor necrosis factor biosynthesis and stabilization of p38 MAPK.
Volume: 27
Issue: 1
Pages: 170-81
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Publication
19219045 | J:199705
First Author: Catalanotti F
Year: 2009
Journal: Nat Struct Mol Biol
Title: A Mek1-Mek2 heterodimer determines the strength and duration of the Erk signal.
Volume: 16
Issue: 3
Pages: 294-303
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Publication
9155017 | J:40024
First Author: Waskiewicz AJ
Year: 1997
Journal: EMBO J
Title: Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2.
Volume: 16
Issue: 8
Pages: 1909-20
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Publication
35550069 | J:333405
First Author: Kurtzeborn K
Year: 2022
Journal: BMC Biol
Title: Comparative whole-genome transcriptome analysis in renal cell populations reveals high tissue specificity of MAPK/ERK targets in embryonic kidney.
Volume: 20
Issue: 1
Pages: 112
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Publication
24126911 | J:204975
First Author: Rastogi R
Year: 2013
Journal: J Biol Chem
Title: Rapamycin induces mitogen-activated protein (MAP) kinase phosphatase-1 (MKP-1) expression through activation of protein kinase B and mitogen-activated protein kinase kinase pathways.
Volume: 288
Issue: 47
Pages: 33966-77
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Publication
23945236 | J:201597
First Author: Shim JH
Year: 2013
Journal: J Clin Invest
Title: Schnurri-3 regulates ERK downstream of WNT signaling in osteoblasts.
Volume: 123
Issue: 9
Pages: 4010-22
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Publication
17210639 | J:118899
First Author: Kim KA
Year: 2007
Journal: Mol Cell Biol
Title: Pref-1 (preadipocyte factor 1) activates the MEK/extracellular signal-regulated kinase pathway to inhibit adipocyte differentiation.
Volume: 27
Issue: 6
Pages: 2294-308
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Publication
22465219 | J:327866
First Author: Taguchi K
Year: 2012
Journal: Pharmacol Res
Title: Angiotensin II type 2 receptor-dependent increase in nitric oxide synthase activity in the endothelium of db/db mice is mediated via a MEK pathway.
Volume: 66
Issue: 1
Pages: 41-50
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Publication
21144847 | J:168104
First Author: Goettel JA
Year: 2011
Journal: Exp Cell Res
Title: KSR1 is a functional protein kinase capable of serine autophosphorylation and direct phosphorylation of MEK1.
Volume: 317
Issue: 4
Pages: 452-63
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Publication
18203667 | J:131397
First Author: Cho KW
Year: 2008
Journal: Gene Expr Patterns
Title: Expression of phosphorylated forms of ERK, MEK, PTEN and PI3K in mouse oral development.
Volume: 8
Issue: 4
Pages: 284-90
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Publication
19551815 | J:154797
First Author: Cho KW
Year: 2009
Journal: J Exp Zool B Mol Dev Evol
Title: ERK activation is involved in tooth development via FGF10 signaling.
Volume: 312
Issue: 8
Pages: 901-11
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Publication
8297798 | J:21571
First Author: Brott BK
Year: 1993
Journal: Cell Growth Differ
Title: MEK2 is a kinase related to MEK1 and is differentially expressed in murine tissues.
Volume: 4
Issue: 11
Pages: 921-9
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Publication
21514245 | J:172200
First Author: Blasco RB
Year: 2011
Journal: Cancer Cell
Title: c-Raf, but not B-Raf, is essential for development of K-Ras oncogene-driven non-small cell lung carcinoma.
Volume: 19
Issue: 5
Pages: 652-63
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Publication
18952847 | J:144862
First Author: Newbern J
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development.
Volume: 105
Issue: 44
Pages: 17115-20
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Publication
21383153 | J:170095
First Author: Urosevic J
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Constitutive activation of B-Raf in the mouse germ line provides a model for human cardio-facio-cutaneous syndrome.
Volume: 108
Issue: 12
Pages: 5015-20
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Publication
33331896 | J:338790
First Author: Cui Y
Year: 2021
Journal: Hum Mol Genet
Title: Merlin cooperates with neurofibromin and Spred1 to suppress the Ras-Erk pathway.
Volume: 29
Issue: 23
Pages: 3793-3806
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8668348 | J:33414
First Author: Papin C
Year: 1996
Journal: Oncogene
Title: Identification of signalling proteins interacting with B-Raf in the yeast two-hybrid system.
Volume: 12
Issue: 10
Pages: 2213-21
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Publication
23468876 | J:198271
First Author: Lin CY
Year: 2013
Journal: PLoS One
Title: Hyperglycemia: GDNF-EGR1 pathway target renal epithelial cell migration and apoptosis in diabetic renal embryopathy.
Volume: 8
Issue: 2
Pages: e56731
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Publication
34010630 | J:321004
First Author: Jiang M
Year: 2021
Journal: Dev Cell
Title: VEGF receptor 2 (KDR) protects airways from mucus metaplasia through a Sox9-dependent pathway.
Volume: 56
Issue: 11
Pages: 1646-1660.e5
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Publication
23920377 | J:204095
First Author: Remeseiro S
Year: 2013
Journal: Biochim Biophys Acta
Title: Reduction of Nipbl impairs cohesin loading locally and affects transcription but not cohesion-dependent functions in a mouse model of Cornelia de Lange Syndrome.
Volume: 1832
Issue: 12
Pages: 2097-102
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Publication
26435415 | J:227204
First Author: Li A
Year: 2015
Journal: Am J Pathol
Title: Human polycystin-2 transgene dose-dependently rescues ADPKD phenotypes in Pkd2 mutant mice.
Volume: 185
Issue: 10
Pages: 2843-60
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24493648 | J:207470
First Author: Sheean ME
Year: 2014
Journal: Genes Dev
Title: Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination.
Volume: 28
Issue: 3
Pages: 290-303
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Publication
19017799 | J:142212
First Author: Krenz M
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Role of ERK1/2 signaling in congenital valve malformations in Noonan syndrome.
Volume: 105
Issue: 48
Pages: 18930-5
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Publication
18619436 | J:138857
First Author: Hislop NR
Year: 2008
Journal: Dev Biol
Title: Grhl3 and Lmo4 play coordinate roles in epidermal migration.
Volume: 321
Issue: 1
Pages: 263-72
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16432225 | J:105998
First Author: Galabova-Kovacs G
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Essential role of B-Raf in ERK activation during extraembryonic development.
Volume: 103
Issue: 5
Pages: 1325-30
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Publication
17707671 | J:127326
First Author: Elsaid AF
Year: 2007
Journal: Mol Genet Metab
Title: Differential perturbation of the Fgf/Erk1/2 and Shh pathways in the C57BL/6N and SWV embryonic limb buds after mid-gestational cadmium chloride administration.
Volume: 92
Issue: 3
Pages: 258-70
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23469020 | J:199499
First Author: Gerhardt C
Year: 2013
Journal: PLoS One
Title: The ciliary protein Ftm is required for ventricular wall and septal development.
Volume: 8
Issue: 2
Pages: e57545
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26848828 | J:230714
   
First Author: Xing L
Year: 2016
Journal: Elife
Title: Layer specific and general requirements for ERK/MAPK signaling in the developing neocortex.
Volume: 5
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27748998 | J:237426
First Author: Boucherat O
Year: 2017
Journal: Dev Dyn
Title: Lung development requires an active ERK/MAPK pathway in the lung mesenchyme.
Volume: 246
Issue: 1
Pages: 72-82
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27799550 | J:283483
First Author: Mathew G
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Targeting of Ras-mediated FGF signaling suppresses Pten-deficient skin tumor.
Volume: 113
Issue: 46
Pages: 13156-13161
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18760695 | J:145464
First Author: Brinkmann BG
Year: 2008
Journal: Neuron
Title: Neuregulin-1/ErbB signaling serves distinct functions in myelination of the peripheral and central nervous system.
Volume: 59
Issue: 4
Pages: 581-95
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31424120 | J:282259
First Author: Gal H
Year: 2019
Journal: EMBO J
Title: Molecular pathways of senescence regulate placental structure and function.
Volume: 38
Issue: 18
Pages: e100849
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20884876 | J:182094
First Author: Huang ZP
Year: 2010
Journal: Arterioscler Thromb Vasc Biol
Title: Loss of microRNAs in neural crest leads to cardiovascular syndromes resembling human congenital heart defects.
Volume: 30
Issue: 12
Pages: 2575-86
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10704452 | J:75421
First Author: Garratt AN
Year: 2000
Journal: J Cell Biol
Title: A dual role of erbB2 in myelination and in expansion of the schwann cell precursor pool.
Volume: 148
Issue: 5
Pages: 1035-46
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20530870 | J:163721
First Author: Yang T
Year: 2010
Journal: J Clin Invest
Title: E-selectin ligand-1 regulates growth plate homeostasis in mice by inhibiting the intracellular processing and secretion of mature TGF-beta.
Volume: 120
Issue: 7
Pages: 2474-85
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15509711 | J:93217
First Author: Liu J
Year: 2004
Journal: Reproduction
Title: Serine-threonine kinases and transcription factors active in signal transduction are detected at high levels of phosphorylation during mitosis in preimplantation embryos and trophoblast stem cells.
Volume: 128
Issue: 5
Pages: 643-54
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15305288 | J:91734
First Author: Wang Y
Year: 2004
Journal: Dev Dyn
Title: Entire mitogen activated protein kinase (MAPK) pathway is present in preimplantation mouse embryos.
Volume: 231
Issue: 1
Pages: 72-87
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33277484 | J:300967
First Author: Pajovic S
Year: 2020
Journal: Nat Commun
Title: Epigenetic activation of a RAS/MYC axis in H3.3K27M-driven cancer.
Volume: 11
Issue: 1
Pages: 6216
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20019329 | J:170883
First Author: Huang J
Year: 2010
Journal: Circ Res
Title: Fibulin-4 deficiency results in ascending aortic aneurysms: a potential link between abnormal smooth muscle cell phenotype and aneurysm progression.
Volume: 106
Issue: 3
Pages: 583-92
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32043969 | J:290269
   
First Author: Garg A
Year: 2020
Journal: Elife
Title: Etv transcription factors functionally diverge from their upstream FGF signaling in lens development.
Volume: 9
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24603431 | J:210997
First Author: Ihermann-Hella A
Year: 2014
Journal: PLoS Genet
Title: Mitogen-activated protein kinase (MAPK) pathway regulates branching by remodeling epithelial cell adhesion.
Volume: 10
Issue: 3
Pages: e1004193
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30188892 | J:266214
First Author: Garg A
Year: 2018
Journal: PLoS Genet
Title: FGF-induced Pea3 transcription factors program the genetic landscape for cell fate determination.
Volume: 14
Issue: 9
Pages: e1007660
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22998872 | J:188328
First Author: Li X
Year: 2012
Journal: Neuron
Title: MEK Is a Key Regulator of Gliogenesis in the Developing Brain.
Volume: 75
Issue: 6
Pages: 1035-50
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21965329 | J:178461
First Author: Pearson HB
Year: 2011
Journal: J Clin Invest
Title: SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia.
Volume: 121
Issue: 11
Pages: 4257-67
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24733831 | J:213126
First Author: O'Donovan KJ
Year: 2014
Journal: J Exp Med
Title: B-RAF kinase drives developmental axon growth and promotes axon regeneration in the injured mature CNS.
Volume: 211
Issue: 5
Pages: 801-14
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17396120 | J:121660
First Author: Zhong J
Year: 2007
Journal: Nat Neurosci
Title: Raf kinase signaling functions in sensory neuron differentiation and axon growth in vivo.
Volume: 10
Issue: 5
Pages: 598-607
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25926459 | J:221658
First Author: Vithayathil J
Year: 2015
Journal: J Neurosci
Title: Dentate Gyrus Development Requires ERK Activity to Maintain Progenitor Population and MAPK Pathway Feedback Regulation.
Volume: 35
Issue: 17
Pages: 6836-48
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33227706 | J:308923
 
First Author: Li Z
Year: 2021
Journal: Biomed Pharmacother
Title: SCAP knockout in SM22α-Cre mice induces defective angiogenesis in the placental labyrinth.
Volume: 133
Pages: 111011
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27122033 | J:231817
First Author: Matsumoto S
Year: 2016
Journal: J Neurosci
Title: Motor Nerve Arborization Requires Proteolytic Domain of Damage-Induced Neuronal Endopeptidase (DINE) during Development.
Volume: 36
Issue: 17
Pages: 4744-57
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19047410 | J:143745
First Author: Kamda JD
Year: 2009
Journal: Infect Immun
Title: Phosphoinositide 3-kinase-dependent inhibition of dendritic cell interleukin-12 production by Giardia lamblia.
Volume: 77
Issue: 2
Pages: 685-93
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Publication
10984455 | J:64475
First Author: Puttagunta R
Year: 2000
Journal: Genome Res
Title: Comparative maps of human 19p13.3 and mouse chromosome 10 allow identification of sequences at evolutionary breakpoints.
Volume: 10
Issue: 9
Pages: 1369-80
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17177285 | J:117790
First Author: Singh S
Year: 2007
Journal: Birth Defects Res A Clin Mol Teratol
Title: Molecular profiles of mitogen activated protein kinase signaling pathways in orofacial development.
Volume: 79
Issue: 1
Pages: 35-44
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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