Type |
Details |
Score |
Publication |
First Author: |
Moriya H |
Year: |
2011 |
Journal: |
Arch Biochem Biophys |
Title: |
Secretion of three enzymes for fatty acid synthesis into mouse milk in association with fat globules, and rapid decrease of the secreted enzymes by treatment with rapamycin. |
Volume: |
508 |
Issue: |
1 |
Pages: |
87-92 |
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•
•
•
•
•
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Publication |
First Author: |
Jackson KC |
Year: |
2014 |
Journal: |
J Lipid Res |
Title: |
BRCA1 is a novel regulator of metabolic function in skeletal muscle. |
Volume: |
55 |
Issue: |
4 |
Pages: |
668-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Salles J |
Year: |
2003 |
Journal: |
Biochim Biophys Acta |
Title: |
Acetyl-CoA carboxylase and SREBP expression during peripheral nervous system myelination. |
Volume: |
1631 |
Issue: |
3 |
Pages: |
229-38 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fullerton MD |
Year: |
2013 |
Journal: |
Nat Med |
Title: |
Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin. |
Volume: |
19 |
Issue: |
12 |
Pages: |
1649-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chuang SJ |
Year: |
2021 |
Journal: |
Biochem J |
Title: |
AMPK activation by SC4 inhibits noradrenaline-induced lipolysis and insulin-stimulated lipogenesis in white adipose tissue. |
Volume: |
478 |
Issue: |
21 |
Pages: |
3869-3889 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lepropre S |
Year: |
2018 |
Journal: |
Blood |
Title: |
AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation. |
Volume: |
132 |
Issue: |
11 |
Pages: |
1180-1192 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hawley SA |
Year: |
2016 |
Journal: |
Diabetes |
Title: |
The Na+/Glucose Cotransporter Inhibitor Canagliflozin Activates AMPK by Inhibiting Mitochondrial Function and Increasing Cellular AMP Levels. |
Volume: |
65 |
Issue: |
9 |
Pages: |
2784-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Deja S |
Year: |
2024 |
Journal: |
Cell Metab |
Title: |
Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability. |
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•
•
•
•
•
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Publication |
First Author: |
Kim CW |
Year: |
2017 |
Journal: |
Cell Metab |
Title: |
Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation. |
Volume: |
26 |
Issue: |
2 |
Pages: |
394-406.e6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fraser SA |
Year: |
2013 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
AMPK couples plasma renin to cellular metabolism by phosphorylation of ACC1. |
Volume: |
305 |
Issue: |
5 |
Pages: |
F679-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Day EA |
Year: |
2019 |
Journal: |
Nat Metab |
Title: |
Metformin-induced increases in GDF15 are important for suppressing appetite and promoting weight loss. |
Volume: |
1 |
Issue: |
12 |
Pages: |
1202-1208 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guilherme A |
Year: |
2023 |
Journal: |
Cell Rep |
Title: |
Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program. |
Volume: |
42 |
Issue: |
5 |
Pages: |
112488 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kanno T |
Year: |
2021 |
Journal: |
Commun Biol |
Title: |
SCD2-mediated monounsaturated fatty acid metabolism regulates cGAS-STING-dependent type I IFN responses in CD4(+) T cells. |
Volume: |
4 |
Issue: |
1 |
Pages: |
820 |
|
•
•
•
•
•
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Publication |
First Author: |
Patel DD |
Year: |
2001 |
Journal: |
J Lipid Res |
Title: |
Disturbances in the normal regulation of SREBP-sensitive genes in PPAR alpha-deficient mice. |
Volume: |
42 |
Issue: |
3 |
Pages: |
328-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Qi L |
Year: |
2006 |
Journal: |
Science |
Title: |
TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism. |
Volume: |
312 |
Issue: |
5781 |
Pages: |
1763-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shinmura K |
Year: |
2007 |
Journal: |
Circulation |
Title: |
Cardioprotective effects of short-term caloric restriction are mediated by adiponectin via activation of AMP-activated protein kinase. |
Volume: |
116 |
Issue: |
24 |
Pages: |
2809-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Qu B |
Year: |
2016 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Sirtuin1 promotes osteogenic differentiation through downregulation of peroxisome proliferator-activated receptor γ in MC3T3-E1 cells. |
Volume: |
478 |
Issue: |
1 |
Pages: |
439-445 |
|
•
•
•
•
•
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Publication |
First Author: |
Ortiz-Miranda S |
Year: |
2016 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
A novel transgenic mouse model of lysosomal storage disorder. |
Volume: |
311 |
Issue: |
5 |
Pages: |
G903-G919 |
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•
•
•
•
•
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Publication |
First Author: |
Kaltenecker D |
Year: |
2017 |
Journal: |
Diabetologia |
Title: |
Adipocyte STAT5 deficiency promotes adiposity and impairs lipid mobilisation in mice. |
Volume: |
60 |
Issue: |
2 |
Pages: |
296-305 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yashirogi S |
Year: |
2021 |
Journal: |
EMBO Rep |
Title: |
AMPK regulates cell shape of cardiomyocytes by modulating turnover of microtubules through CLIP-170. |
Volume: |
22 |
Issue: |
1 |
Pages: |
e50949 |
|
•
•
•
•
•
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Publication |
First Author: |
Martins L |
Year: |
2016 |
Journal: |
Cell Rep |
Title: |
A Functional Link between AMPK and Orexin Mediates the Effect of BMP8B on Energy Balance. |
Volume: |
16 |
Issue: |
8 |
Pages: |
2231-2242 |
|
•
•
•
•
•
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Publication |
First Author: |
Stone SJ |
Year: |
2004 |
Journal: |
J Biol Chem |
Title: |
Lipopenia and skin barrier abnormalities in DGAT2-deficient mice. |
Volume: |
279 |
Issue: |
12 |
Pages: |
11767-76 |
|
•
•
•
•
•
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Publication |
First Author: |
Zhang Y |
Year: |
2016 |
Journal: |
Am J Pathol |
Title: |
Inhibition of Poly(ADP-Ribose) Polymerase-1 Protects Chronic Alcoholic Liver Injury. |
Volume: |
186 |
Issue: |
12 |
Pages: |
3117-3130 |
|
•
•
•
•
•
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Publication |
First Author: |
Wang T |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
The AMPK-HOXB9-KRAS axis regulates lung adenocarcinoma growth in response to cellular energy alterations. |
Volume: |
40 |
Issue: |
8 |
Pages: |
111210 |
|
•
•
•
•
•
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Publication |
First Author: |
Myöhänen S |
Year: |
1994 |
Journal: |
DNA Seq |
Title: |
Nucleotide sequence of mouse spermidine synthase cDNA. |
Volume: |
4 |
Issue: |
5 |
Pages: |
343-6 |
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•
•
•
•
•
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Publication |
First Author: |
Través PG |
Year: |
2013 |
Journal: |
J Immunol |
Title: |
Selective impairment of P2Y signaling by prostaglandin E2 in macrophages: implications for Ca2+-dependent responses. |
Volume: |
190 |
Issue: |
8 |
Pages: |
4226-35 |
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•
•
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•
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Publication |
First Author: |
Williams T |
Year: |
2011 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
AMP-activated protein kinase (AMPK) activity is not required for neuronal development but regulates axogenesis during metabolic stress. |
Volume: |
108 |
Issue: |
14 |
Pages: |
5849-54 |
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Publication |
First Author: |
Chen L |
Year: |
2016 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Disruption of the AMPK-TBC1D1 nexus increases lipogenic gene expression and causes obesity in mice via promoting IGF1 secretion. |
Volume: |
113 |
Issue: |
26 |
Pages: |
7219-24 |
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Publication |
First Author: |
Clar J |
Year: |
2014 |
Journal: |
Kidney Int |
Title: |
Targeted deletion of kidney glucose-6 phosphatase leads to nephropathy. |
Volume: |
86 |
Issue: |
4 |
Pages: |
747-56 |
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Publication |
First Author: |
Shimano H |
Year: |
1996 |
Journal: |
J Clin Invest |
Title: |
Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a. |
Volume: |
98 |
Issue: |
7 |
Pages: |
1575-84 |
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Publication |
First Author: |
Vergnes L |
Year: |
2016 |
Journal: |
J Lipid Res |
Title: |
SREBP-2-deficient and hypomorphic mice reveal roles for SREBP-2 in embryonic development and SREBP-1c expression. |
Volume: |
57 |
Issue: |
3 |
Pages: |
410-21 |
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Publication |
First Author: |
Cossette SM |
Year: |
2014 |
Journal: |
Biol Open |
Title: |
Sucrose non-fermenting related kinase enzyme is essential for cardiac metabolism. |
Volume: |
4 |
Issue: |
1 |
Pages: |
48-61 |
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Publication |
First Author: |
Guo CG |
Year: |
2023 |
Journal: |
Mol Metab |
Title: |
Intestinal SURF4 is essential for apolipoprotein transport and lipoprotein secretion. |
Volume: |
79 |
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Pages: |
101847 |
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Publication |
First Author: |
Kahraman S |
Year: |
2014 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
Maternal insulin resistance and transient hyperglycemia impact the metabolic and endocrine phenotypes of offspring. |
Volume: |
307 |
Issue: |
10 |
Pages: |
E906-18 |
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Publication |
First Author: |
Beigneux AP |
Year: |
2004 |
Journal: |
J Biol Chem |
Title: |
ATP-citrate lyase deficiency in the mouse. |
Volume: |
279 |
Issue: |
10 |
Pages: |
9557-64 |
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Publication |
First Author: |
Hong AE |
Year: |
2018 |
Journal: |
Mol Cells |
Title: |
PPARα-Target Gene Expression Requires TIS21/BTG2 Gene in Liver of the C57BL/6 Mice under Fasting Condition. |
Volume: |
41 |
Issue: |
2 |
Pages: |
140-149 |
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Publication |
First Author: |
Vila IK |
Year: |
2017 |
Journal: |
Cancer Cell |
Title: |
A UBE2O-AMPKα2 Axis that Promotes Tumor Initiation and Progression Offers Opportunities for Therapy. |
Volume: |
31 |
Issue: |
2 |
Pages: |
208-224 |
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Publication |
First Author: |
Fonseca TL |
Year: |
2015 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity. |
Volume: |
112 |
Issue: |
45 |
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14018-23 |
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Publication |
First Author: |
Luo X |
Year: |
2016 |
Journal: |
Cell Rep |
Title: |
Dual Shp2 and Pten Deficiencies Promote Non-alcoholic Steatohepatitis and Genesis of Liver Tumor-Initiating Cells. |
Volume: |
17 |
Issue: |
11 |
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2979-2993 |
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First Author: |
Qiao L |
Year: |
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Journal: |
Diabetes |
Title: |
Adiponectin enhances mouse fetal fat deposition. |
Volume: |
61 |
Issue: |
12 |
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3199-207 |
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First Author: |
Hezel AF |
Year: |
2008 |
Journal: |
Mol Cell Biol |
Title: |
Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. |
Volume: |
28 |
Issue: |
7 |
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2414-25 |
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First Author: |
Lu J |
Year: |
2017 |
Journal: |
EMBO Rep |
Title: |
The phosphorylation status of T522 modulates tissue-specific functions of SIRT1 in energy metabolism in mice. |
Volume: |
18 |
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5 |
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841-857 |
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First Author: |
Li H |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
Destabilization of TP53 by USP10 is essential for neonatal autophagy and survival. |
Volume: |
41 |
Issue: |
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Publication |
First Author: |
Dasgupta B |
Year: |
2009 |
Journal: |
Dev Cell |
Title: |
AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development. |
Volume: |
16 |
Issue: |
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256-70 |
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First Author: |
Lee KY |
Year: |
2015 |
Journal: |
Nat Commun |
Title: |
Tbx15 controls skeletal muscle fibre-type determination and muscle metabolism. |
Volume: |
6 |
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First Author: |
Breckenridge RA |
Year: |
2013 |
Journal: |
PLoS Biol |
Title: |
Hypoxic regulation of hand1 controls the fetal-neonatal switch in cardiac metabolism. |
Volume: |
11 |
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First Author: |
Kim GE |
Year: |
2015 |
Journal: |
Cardiovasc Res |
Title: |
LKB1 deletion causes early changes in atrial channel expression and electrophysiology prior to atrial fibrillation. |
Volume: |
108 |
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First Author: |
Ansarullah |
Year: |
2021 |
Journal: |
Nature |
Title: |
Inceptor counteracts insulin signalling in β-cells to control glycaemia. |
Volume: |
590 |
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First Author: |
Song Z |
Year: |
2022 |
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Mol Metab |
Title: |
The conserved Mediator subunit cyclin C (CCNC) is required for brown adipocyte development and lipid accumulation. |
Volume: |
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Year: |
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Nat Commun |
Title: |
14-3-3ζ coordinates adipogenesis of visceral fat. |
Volume: |
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First Author: |
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Year: |
2021 |
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Biochim Biophys Acta Mol Basis Dis |
Title: |
A long non-coding RNA specifically expressed in early embryos programs the metabolic balance in adult mice. |
Volume: |
1867 |
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First Author: |
Muñoz-Gallardo MDM |
Year: |
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Sci Rep |
Title: |
miR-195b is required for proper cellular homeostasis in the elderly. |
Volume: |
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First Author: |
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Year: |
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PLoS Genet |
Title: |
Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury. |
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First Author: |
Shanghai Model Organisms Center |
Year: |
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Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
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A mitochondrial protein compendium elucidates complex I disease biology. |
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Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database |
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Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
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First Author: |
GemPharmatech |
Year: |
2020 |
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Title: |
GemPharmatech Website. |
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Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
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Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
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Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
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Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
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Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
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Title: |
Annotation inferences using phylogenetic trees |
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
552
|
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
559
|
Fragment?: |
false |
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Publication |
First Author: |
Travers MT |
Year: |
2005 |
Journal: |
Genomics |
Title: |
Asymmetric expression of transcripts derived from the shared promoter between the divergently oriented ACACA and TADA2L genes. |
Volume: |
85 |
Issue: |
1 |
Pages: |
71-84 |
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Allele |
Name: |
acetyl-Coenzyme A carboxylase alpha; targeted mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, No functional change |
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Strain |
Attribute String: |
coisogenic, targeted mutation, mutant strain |
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Publication |
First Author: |
Okada N |
Year: |
2023 |
Journal: |
Commun Biol |
Title: |
NFYA promotes malignant behavior of triple-negative breast cancer in mice through the regulation of lipid metabolism. |
Volume: |
6 |
Issue: |
1 |
Pages: |
596 |
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Publication |
First Author: |
Monteuuis G |
Year: |
2017 |
Journal: |
Biochem J |
Title: |
A conserved mammalian mitochondrial isoform of acetyl-CoA carboxylase ACC1 provides the malonyl-CoA essential for mitochondrial biogenesis in tandem with ACSF3. |
Volume: |
474 |
Issue: |
22 |
Pages: |
3783-3797 |
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