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Search results 4401 to 4500 out of 4549 for App

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Category: Publication
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Type Details Score
Publication
26868295 | J:246319
First Author: Goldsworthy M
Year: 2016
Journal: Diabetes
Title: Haploinsufficiency of the Insulin Receptor in the Presence of a Splice-Site Mutation in Ppp2r2a Results in a Novel Digenic Mouse Model of Type 2 Diabetes.
Volume: 65
Issue: 5
Pages: 1434-46
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Publication
23418567 | J:197198
First Author: Garringer HJ
Year: 2013
Journal: PLoS One
Title: Increased tau phosphorylation and tau truncation, and decreased synaptophysin levels in mutant BRI2/tau transgenic mice.
Volume: 8
Issue: 2
Pages: e56426
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Publication
11549720 | J:71536
First Author: Cowan CM
Year: 2001
Journal: J Neurosci
Title: Caspases 3 and 9 send a pro-apoptotic signal from synapse to cell body in olfactory receptor neurons.
Volume: 21
Issue: 18
Pages: 7099-109
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Publication
12082633 | J:76678
First Author: Fleischer A
Year: 2002
Journal: Oncogene
Title: Proapoptotic activity of ITM2B(s), a BH3-only protein induced upon IL-2-deprivation which interacts with Bcl-2.
Volume: 21
Issue: 20
Pages: 3181-9
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Publication
18021291 | J:141555
First Author: Lopez JR
Year: 2008
Journal: J Neurochem
Title: Increased intraneuronal resting [Ca2+] in adult Alzheimer's disease mice.
Volume: 105
Issue: 1
Pages: 262-71
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Publication
21835156 | J:176301
First Author: Montgomery SL
Year: 2011
Journal: Am J Pathol
Title: Ablation of TNF-RI/RII expression in Alzheimer's disease mice leads to an unexpected enhancement of pathology: implications for chronic pan-TNF-α suppressive therapeutic strategies in the brain.
Volume: 179
Issue: 4
Pages: 2053-70
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Publication
25339759 | J:217151
First Author: Shibuya Y
Year: 2014
Journal: J Neurosci
Title: Inhibiting ACAT1/SOAT1 in microglia stimulates autophagy-mediated lysosomal proteolysis and increases Aβ1-42 clearance.
Volume: 34
Issue: 43
Pages: 14484-501
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Publication
25447943 | J:231418
 
First Author: Hohsfield LA
Year: 2014
Journal: Mol Cell Neurosci
Title: Vascular pathology of 20-month-old hypercholesterolemia mice in comparison to triple-transgenic and APPSwDI Alzheimer's disease mouse models.
Volume: 63
Pages: 83-95
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Publication
29358916 | J:310530
 
First Author: Yang S
Year: 2017
Journal: Front Aging Neurosci
Title: Reducing the Levels of Akt Activation by PDK1 Knock-in Mutation Protects Neuronal Cultures against Synthetic Amyloid-Beta Peptides.
Volume: 9
Pages: 435
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Publication
21704011 | J:174403
First Author: Medeiros R
Year: 2011
Journal: Am J Pathol
Title: Loss of muscarinic M1 receptor exacerbates Alzheimer's disease-like pathology and cognitive decline.
Volume: 179
Issue: 2
Pages: 980-91
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Publication
31004063 | J:274643
First Author: Xiang J
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Delta-secretase-cleaved Tau antagonizes TrkB neurotrophic signalings, mediating Alzheimer's disease pathologies.
Volume: 116
Issue: 18
Pages: 9094-9102
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Publication
30850634 | J:275633
First Author: Caberlotto L
Year: 2019
Journal: Sci Rep
Title: Cross-disease analysis of Alzheimer's disease and type-2 Diabetes highlights the role of autophagy in the pathophysiology of two highly comorbid diseases.
Volume: 9
Issue: 1
Pages: 3965
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Publication
22367970 | J:183771
First Author: Manczak M
Year: 2012
Journal: Hum Mol Genet
Title: Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage.
Volume: 21
Issue: 11
Pages: 2538-47
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Publication
36843263 | J:338361
First Author: Kim SH
Year: 2023
Journal: Autophagy
Title: Endolysosomal impairment by binding of amyloid beta or MAPT/Tau to V-ATPase and rescue via the HYAL-CD44 axis in Alzheimer disease.
Volume: 19
Issue: 8
Pages: 2318-2337
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Publication
27155503 | J:242424
First Author: Hargis KE
Year: 2017
Journal: Behav Brain Res
Title: Transcriptional signatures of brain aging and Alzheimer's disease: What are our rodent models telling us?
Volume: 322
Issue: Pt B
Pages: 311-328
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Publication
20133765 | J:157545
First Author: Bryleva EY
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD.
Volume: 107
Issue: 7
Pages: 3081-6
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Publication
21235806 | J:194454
First Author: Fonseca MI
Year: 2011
Journal: J Neuroinflammation
Title: Contribution of complement activation pathways to neuropathology differs among mouse models of Alzheimer's disease.
Volume: 8
Issue: 1
Pages: 4
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Publication
18800967 | J:141307
First Author: Ribe EM
Year: 2008
Journal: Biochem J
Title: Mechanisms of neuronal death in disease: defining the models and the players.
Volume: 415
Issue: 2
Pages: 165-82
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Publication
20305648 | J:159680
First Author: Fuhrmann M
Year: 2010
Journal: Nat Neurosci
Title: Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease.
Volume: 13
Issue: 4
Pages: 411-3
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Publication
30525042 | J:268837
 
First Author: Sabbir MG
Year: 2018
Journal: Front Mol Biosci
Title: Loss of Ca2+/Calmodulin Dependent Protein Kinase Kinase 2 Leads to Aberrant Transferrin Phosphorylation and Trafficking: A Potential Biomarker for Alzheimer's Disease.
Volume: 5
Pages: 99
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Publication
29024660 | J:253213
First Author: Zhao Y
Year: 2017
Journal: Neuron
Title: Amyloid Beta Peptides Block New Synapse Assembly by Nogo Receptor-Mediated Inhibition of T-Type Calcium Channels.
Volume: 96
Issue: 2
Pages: 355-372.e6
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Publication
33192524 | J:313486
 
First Author: Iyaswamy A
Year: 2020
Journal: Front Pharmacol
Title: Yuan-Hu Zhi Tong Prescription Mitigates Tau Pathology and Alleviates Memory Deficiency in the Preclinical Models of Alzheimer's Disease.
Volume: 11
Pages: 584770
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Publication
30120733 | J:285073
First Author: Comerota MM
Year: 2019
Journal: Mol Neurobiol
Title: Near Infrared Light Treatment Reduces Synaptic Levels of Toxic Tau Oligomers in Two Transgenic Mouse Models of Human Tauopathies.
Volume: 56
Issue: 5
Pages: 3341-3355
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Publication
24068166 | J:201811
First Author: Bhutta MF
Year: 2013
Journal: Mamm Genome
Title: Surveying the Down syndrome mouse model resource identifies critical regions responsible for chronic otitis media.
Volume: 24
Issue: 11-12
Pages: 439-45
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Publication
27195491 | J:231889
First Author: Peiris H
Year: 2016
Journal: PLoS Genet
Title: A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes.
Volume: 12
Issue: 5
Pages: e1006033
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Publication
37014740 | J:337878
First Author: Xing Z
Year: 2023
Journal: Hum Mol Genet
Title: Dissection of a Down syndrome-associated trisomy to separate the gene dosage-dependent and -independent effects of an extra chromosome.
Volume: 32
Issue: 13
Pages: 2205-2218
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Publication
30998504 | J:284087
   
First Author: Schill EM
Year: 2019
Journal: JCI Insight
Title: Down syndrome mouse models have an abnormal enteric nervous system.
Volume: 5
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Publication
31235644 | J:283607
First Author: Kubo A
Year: 2019
Journal: J Neurosci
Title: Ectopic Expression Induces Abnormal Somatodendritic Distribution of Tau in the Mouse Brain.
Volume: 39
Issue: 34
Pages: 6781-6797
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Publication
37118504 | J:337860
First Author: Dejanovic B
Year: 2022
Journal: Nat Aging
Title: Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer's disease mouse models.
Volume: 2
Issue: 9
Pages: 837-850
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Publication
32776088 | J:332749
First Author: Fowler AJ
Year: 2020
Journal: Hum Mol Genet
Title: Discoidin Domain Receptor 1 is a therapeutic target for neurodegenerative diseases.
Volume: 29
Issue: 17
Pages: 2882-2898
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Publication
22855807 | J:185792
First Author: Han HJ
Year: 2012
Journal: J Neurosci
Title: Strain background influences neurotoxicity and behavioral abnormalities in mice expressing the tetracycline transactivator.
Volume: 32
Issue: 31
Pages: 10574-86
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Publication
33891876 | J:306299
First Author: Bourdenx M
Year: 2021
Journal: Cell
Title: Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome.
Volume: 184
Issue: 10
Pages: 2696-2714.e25
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Publication
28860088 | J:258530
 
First Author: Angulo SL
Year: 2017
Journal: Neurobiol Dis
Title: Tau and amyloid-related pathologies in the entorhinal cortex have divergent effects in the hippocampal circuit.
Volume: 108
Pages: 261-276
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Publication
26872418 | J:281483
 
First Author: Ferretti MT
Year: 2016
Journal: Brain Behav Immun
Title: T-cell brain infiltration and immature antigen-presenting cells in transgenic models of Alzheimer's disease-like cerebral amyloidosis.
Volume: 54
Pages: 211-225
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Publication
27708157 | J:238628
First Author: Reinders NR
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Amyloid-β effects on synapses and memory require AMPA receptor subunit GluA3.
Volume: 113
Issue: 42
Pages: E6526-E6534
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Publication
34035282 | J:314716
First Author: Alvarez-Vergara MI
Year: 2021
Journal: Nat Commun
Title: Non-productive angiogenesis disassembles Aß plaque-associated blood vessels.
Volume: 12
Issue: 1
Pages: 3098
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Publication
28814543 | J:250614
 
First Author: Le Pichon CE
Year: 2017
Journal: Sci Transl Med
Title: Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease.
Volume: 9
Issue: 403
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Publication
24440716 | J:208793
First Author: Sun X
Year: 2014
Journal: Cell Rep
Title: miR-342-5p decreases ankyrin G levels in Alzheimer's disease transgenic mouse models.
Volume: 6
Issue: 2
Pages: 264-70
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Publication
23175831 | J:192812
First Author: Choi SW
Year: 2012
Journal: J Neurosci
Title: No consistent bioenergetic defects in presynaptic nerve terminals isolated from mouse models of Alzheimer's disease.
Volume: 32
Issue: 47
Pages: 16775-84
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Publication
18256671 | J:132628
First Author: Meyer-Luehmann M
Year: 2008
Journal: Nature
Title: Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease.
Volume: 451
Issue: 7179
Pages: 720-4
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Publication
30311654 | J:279358
First Author: Whitesell JD
Year: 2019
Journal: J Comp Neurol
Title: Whole brain imaging reveals distinct spatial patterns of amyloid beta deposition in three mouse models of Alzheimer's disease.
Volume: 527
Issue: 13
Pages: 2122-2145
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Publication
18516051 | J:137043
First Author: Town T
Year: 2008
Journal: Nat Med
Title: Blocking TGF-beta-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology.
Volume: 14
Issue: 6
Pages: 681-7
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Publication
16899370 | J:113199
First Author: Burgess BL
Year: 2006
Journal: Neurobiol Dis
Title: Elevated plasma triglyceride levels precede amyloid deposition in Alzheimer's disease mouse models with abundant A beta in plasma.
Volume: 24
Issue: 1
Pages: 114-27
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Publication
9791530 | -
First Author: Martin GM
Year: 1998
Journal: Cell Mol Life Sci
Title: Introduction: genetic determinants of mid- and late-life dementias.
Volume: 54
Issue: 9
Pages: 895-6
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Publication
9521418 | -
First Author: Cruts M
Year: 1998
Journal: Hum Mutat
Title: Presenilin mutations in Alzheimer's disease.
Volume: 11
Issue: 3
Pages: 183-90
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
9244438 | J:38472
First Author: Sugino H
Year: 1997
Journal: Genomics
Title: Genomic organization and chromosomal localization of the mouse telencephalin gene, a neuronal member of the ICAM family.
Volume: 43
Issue: 2
Pages: 209-15
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Publication
20945367 | J:341385
First Author: Han C
Year: 2011
Journal: J Cell Physiol
Title: Identification of heat shock protein 5, calnexin and integral membrane protein 2B as Adam7-interacting membrane proteins in mouse sperm.
Volume: 226
Issue: 5
Pages: 1186-95
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Publication
10965130 | J:64407
First Author: Gu Z
Year: 2000
Journal: Cytogenet Cell Genet
Title: The p53-inducible gene EI24/PIG8 localizes to human chromosome 11q23 and the proximal region of mouse chromosome 9.
Volume: 89
Issue: 3-4
Pages: 230-3
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Publication
25002035 | J:218071
First Author: Orre M
Year: 2014
Journal: Neurobiol Aging
Title: Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction.
Volume: 35
Issue: 12
Pages: 2746-2760
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Publication
27425031 | J:255474
First Author: Kamphuis W
Year: 2016
Journal: Biochim Biophys Acta
Title: Transcriptional profiling of CD11c-positive microglia accumulating around amyloid plaques in a mouse model for Alzheimer's disease.
Volume: 1862
Issue: 10
Pages: 1847-60
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Publication
37358017 | J:339350
First Author: Marinho D
Year: 2023
Journal: Aging Cell
Title: Reduction of class I histone deacetylases ameliorates ER-mitochondria cross-talk in Alzheimer's disease.
Volume: 22
Issue: 8
Pages: e13895
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Publication
27425620 | J:238659
First Author: Liebmann T
Year: 2016
Journal: Cell Rep
Title: Three-Dimensional Study of Alzheimer's Disease Hallmarks Using the iDISCO Clearing Method.
Volume: 16
Issue: 4
Pages: 1138-1152
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Publication
31467276 | J:279320
First Author: Jadiya P
Year: 2019
Journal: Nat Commun
Title: Impaired mitochondrial calcium efflux contributes to disease progression in models of Alzheimer's disease.
Volume: 10
Issue: 1
Pages: 3885
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Publication
29113959 | J:260831
 
First Author: Lardenoije R
Year: 2018
Journal: Mol Cell Neurosci
Title: Age-related epigenetic changes in hippocampal subregions of four animal models of Alzheimer's disease.
Volume: 86
Pages: 1-15
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Publication
25617315 | J:232678
First Author: Clarke JR
Year: 2015
Journal: EMBO Mol Med
Title: Alzheimer-associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation.
Volume: 7
Issue: 2
Pages: 190-210
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Publication
22912745 | J:189978
First Author: Kamphuis W
Year: 2012
Journal: PLoS One
Title: GFAP isoforms in adult mouse brain with a focus on neurogenic astrocytes and reactive astrogliosis in mouse models of Alzheimer disease.
Volume: 7
Issue: 8
Pages: e42823
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Publication
26982728 | J:232713
First Author: Roy DS
Year: 2016
Journal: Nature
Title: Memory retrieval by activating engram cells in mouse models of early Alzheimer's disease.
Volume: 531
Issue: 7595
Pages: 508-12
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Publication
32098978 | J:293886
First Author: Jiang H
Year: 2020
Journal: Sci Rep
Title: Live Neuron High-Content Screening Reveals Synaptotoxic Activity in Alzheimer Mouse Model Homogenates.
Volume: 10
Issue: 1
Pages: 3412
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Publication
35339896 | J:322782
 
First Author: Zhou Q
Year: 2022
Journal: EBioMedicine
Title: Human tau accumulation promotes glycogen synthase kinase-3β acetylation and thus upregulates the kinase: A vicious cycle in Alzheimer neurodegeneration.
Volume: 78
Pages: 103970
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Publication
28683325 | J:254503
First Author: Haas LT
Year: 2017
Journal: Cell Rep
Title: Silent Allosteric Modulation of mGluR5 Maintains Glutamate Signaling while Rescuing Alzheimer's Mouse Phenotypes.
Volume: 20
Issue: 1
Pages: 76-88
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Publication
25331900 | J:216662
First Author: Chow HM
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: CDK5 activator protein p25 preferentially binds and activates GSK3β.
Volume: 111
Issue: 45
Pages: E4887-95
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Publication
36260685 | J:330576
First Author: Lacomme M
Year: 2022
Journal: Sci Adv
Title: Numb regulates Tau levels and prevents neurodegeneration in tauopathy mouse models.
Volume: 8
Issue: 42
Pages: eabm4295
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Publication
33663578 | J:311283
First Author: Chen M
Year: 2021
Journal: Mol Neurodegener
Title: Enhancing GABAergic signaling ameliorates aberrant gamma oscillations of olfactory bulb in AD mouse models.
Volume: 16
Issue: 1
Pages: 14
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Publication
27210751 | J:235961
First Author: Hamilton A
Year: 2016
Journal: Cell Rep
Title: Chronic Pharmacological mGluR5 Inhibition Prevents Cognitive Impairment and Reduces Pathogenesis in an Alzheimer Disease Mouse Model.
Volume: 15
Issue: 9
Pages: 1859-65
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Publication
29393544 | J:258731
First Author: Valny M
Year: 2018
Journal: Glia
Title: A single-cell analysis reveals multiple roles of oligodendroglial lineage cells during post-ischemic regeneration.
Volume: 66
Issue: 5
Pages: 1068-1081
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Publication
30742114 | J:277544
First Author: Fang EF
Year: 2019
Journal: Nat Neurosci
Title: Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.
Volume: 22
Issue: 3
Pages: 401-412
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Publication
33955647 | J:311343
First Author: Wu L
Year: 2021
Journal: Aging Cell
Title: Therapeutic efficacy of novel memantine nitrate MN-08 in animal models of Alzheimer's disease.
Volume: 20
Issue: 6
Pages: e13371
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25673868 | J:219873
First Author: Ben Haim L
Year: 2015
Journal: J Neurosci
Title: The JAK/STAT3 pathway is a common inducer of astrocyte reactivity in Alzheimer's and Huntington's diseases.
Volume: 35
Issue: 6
Pages: 2817-29
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Publication
27752775 | J:311368
First Author: Jan A
Year: 2017
Journal: Acta Neuropathol
Title: eEF2K inhibition blocks Aβ42 neurotoxicity by promoting an NRF2 antioxidant response.
Volume: 133
Issue: 1
Pages: 101-119
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Publication
23432034 | J:199628
First Author: Chakravarthy B
Year: 2013
Journal: J Neurochem
Title: A synthetic peptide corresponding to a region of the human pericentriolar material 1 (PCM-1) protein binds β-amyloid (Aβ1-42 ) oligomers.
Volume: 126
Issue: 3
Pages: 415-24
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Publication
30050035 | J:264863
First Author: Wei Y
Year: 2018
Journal: Cell Death Dis
Title: Oxidation of KCNB1 channels in the human brain and in mouse model of Alzheimer's disease.
Volume: 9
Issue: 8
Pages: 820
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Publication
34399854 | J:310473
First Author: Gao FJ
Year: 2021
Journal: Acta Neuropathol Commun
Title: Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates.
Volume: 9
Issue: 1
Pages: 137
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Publication
35021077 | J:321505
First Author: Sheppard K
Year: 2022
Journal: Cell Rep
Title: Stride-level analysis of mouse open field behavior using deep-learning-based pose estimation.
Volume: 38
Issue: 2
Pages: 110231
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Publication
22126738 | J:196862
First Author: Zhang L
Year: 2012
Journal: Bioeng Bugs
Title: Genetic analysis of Down syndrome facilitated by mouse chromosome engineering.
Volume: 3
Issue: 1
Pages: 8-12
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Publication
37079499 | J:344996
First Author: Liu H
Year: 2023
Journal: PLoS Biol
Title: DSCAM gene triplication causes excessive GABAergic synapses in the neocortex in Down syndrome mouse models.
Volume: 21
Issue: 4
Pages: e3002078
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Publication
30504774 | J:268139
First Author: Adorno M
Year: 2018
Journal: Sci Rep
Title: Usp16 modulates Wnt signaling in primary tissues through Cdkn2a regulation.
Volume: 8
Issue: 1
Pages: 17506
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Publication
27538963 | J:242664
First Author: Gupta M
Year: 2016
Journal: Mamm Genome
Title: Mouse models of Down syndrome: gene content and consequences.
Volume: 27
Issue: 11-12
Pages: 538-555
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Publication
26758846 | J:228864
First Author: Lian H
Year: 2016
Journal: J Neurosci
Title: Astrocyte-Microglia Cross Talk through Complement Activation Modulates Amyloid Pathology in Mouse Models of Alzheimer's Disease.
Volume: 36
Issue: 2
Pages: 577-89
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Publication
26931567 | J:233816
First Author: Maeda S
Year: 2016
Journal: EMBO Rep
Title: Expression of A152T human tau causes age-dependent neuronal dysfunction and loss in transgenic mice.
Volume: 17
Issue: 4
Pages: 530-51
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Publication
17785178 | J:126808
First Author: Palop JJ
Year: 2007
Journal: Neuron
Title: Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease.
Volume: 55
Issue: 5
Pages: 697-711
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Publication
21228179 | J:168226
First Author: Roberson ED
Year: 2011
Journal: J Neurosci
Title: Amyloid-β/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease.
Volume: 31
Issue: 2
Pages: 700-11
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Publication
25878292 | J:221673
First Author: Hall AM
Year: 2015
Journal: J Neurosci
Title: Tau-dependent Kv4.2 depletion and dendritic hyperexcitability in a mouse model of Alzheimer's disease.
Volume: 35
Issue: 15
Pages: 6221-30
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Publication
29186695 | J:255230
First Author: Savas JN
Year: 2017
Journal: Cell Rep
Title: Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer's Disease-like Pathology.
Volume: 21
Issue: 9
Pages: 2614-2627
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Publication
16753269 | J:111748
First Author: Melnikova T
Year: 2006
Journal: Neuroscience
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