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Search results 501 to 600 out of 686 for Mdm2

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Category: Publication
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Type Details Score
Publication
28406729 | J:345749
First Author: Kendig RD
Year: 2017
Journal: Cancer Invest
Title: Stabilization of the p53-DNA Complex by the Nuclear Protein Dmp1α.
Volume: 35
Issue: 5
Pages: 301-312
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Publication
- | J:346905
     
First Author: Pradella D
Year: 2023
Journal: bioRxiv
Title: Immortalization and transformation of primary cells mediated by engineered ecDNAs.
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Publication
22952240 | -
First Author: Euskirchen G
Year: 2012
Journal: J Biol Chem
Title: SWI/SNF chromatin-remodeling factors: multiscale analyses and diverse functions.
Volume: 287
Issue: 37
Pages: 30897-905
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Publication
12702766 | J:99823
First Author: Kondo S
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Characterization of cells and gene-targeted mice deficient for the p53-binding kinase homeodomain-interacting protein kinase 1 (HIPK1).
Volume: 100
Issue: 9
Pages: 5431-6
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Publication
29262616 | J:272648
First Author: Aryal NK
Year: 2017
Journal: Oncotarget
Title: Loss of digestive organ expansion factor (Diexf) reveals an essential role during murine embryonic development that is independent of p53.
Volume: 8
Issue: 61
Pages: 103996-104006
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Publication
12782311 | J:83672
First Author: Vega FM
Year: 2003
Journal: FEBS Lett
Title: Expression of the VRK (vaccinia-related kinase) gene family of p53 regulators in murine hematopoietic development.
Volume: 544
Issue: 1-3
Pages: 176-80
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Publication
11779495 | J:88792
First Author: Sharpless NE
Year: 2001
Journal: Mol Cell
Title: Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions.
Volume: 8
Issue: 6
Pages: 1187-96
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Publication
25600590 | J:219719
 
First Author: Wang L
Year: 2015
Journal: Nat Commun
Title: Intracellular CD24 disrupts the ARF-NPM interaction and enables mutational and viral oncogene-mediated p53 inactivation.
Volume: 6
Pages: 5909
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Publication
27499244 | J:241266
 
First Author: Riascos-Bernal DF
Year: 2016
Journal: Nat Commun
Title: β-Catenin C-terminal signals suppress p53 and are essential for artery formation.
Volume: 7
Pages: 12389
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Publication
10344759 | J:55311
First Author: Kamijo T
Year: 1999
Journal: Cancer Res
Title: Loss of the ARF tumor suppressor reverses premature replicative arrest but not radiation hypersensitivity arising from disabled atm function.
Volume: 59
Issue: 10
Pages: 2464-9
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Publication
22331460 | J:184938
First Author: Frazier DP
Year: 2012
Journal: Cancer Res
Title: Dmp1 physically interacts with p53 and positively regulates p53's stability, nuclear localization, and function.
Volume: 72
Issue: 7
Pages: 1740-50
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Publication
29153842 | J:252273
First Author: Todoric J
Year: 2017
Journal: Cancer Cell
Title: Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas.
Volume: 32
Issue: 6
Pages: 824-839.e8
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Publication
37527040 | J:338904
First Author: Yu M
Year: 2023
Journal: Cell Rep
Title: FRMD8 targets both CDK4 activation and RB degradation to suppress colon cancer growth.
Volume: 42
Issue: 8
Pages: 112886
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Publication
25822339 | J:260472
First Author: Puzio-Kuter AM
Year: 2015
Journal: Cell Death Differ
Title: Involvement of tumor suppressors PTEN and p53 in the formation of multiple subtypes of liposarcoma.
Volume: 22
Issue: 11
Pages: 1785-91
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Publication
30244867 | J:270442
First Author: Liu L
Year: 2018
Journal: Cell Stem Cell
Title: Impaired Notch Signaling Leads to a Decrease in p53 Activity and Mitotic Catastrophe in Aged Muscle Stem Cells.
Volume: 23
Issue: 4
Pages: 544-556.e4
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Publication
20841468 | J:164678
First Author: Cheng X
Year: 2010
Journal: Cancer Res
Title: Activation of murine double minute 2 by Akt in mammary epithelium delays mammary involution and accelerates mammary tumorigenesis.
Volume: 70
Issue: 19
Pages: 7684-9
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Publication
14712235 | J:88362
First Author: Steinman HA
Year: 2004
Journal: Oncogene
Title: Absence of p21 partially rescues Mdm4 loss and uncovers an antiproliferative effect of Mdm4 on cell growth.
Volume: 23
Issue: 1
Pages: 303-6
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Publication
18039860 | J:132640
First Author: Matijasevic Z
Year: 2008
Journal: Mol Cell Biol
Title: MdmX promotes bipolar mitosis to suppress transformation and tumorigenesis in p53-deficient cells and mice.
Volume: 28
Issue: 4
Pages: 1265-73
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Publication
32101751 | J:287555
First Author: Niederkorn M
Year: 2020
Journal: Cell Rep
Title: TIFAB Regulates USP15-Mediated p53 Signaling during Stressed and Malignant Hematopoiesis.
Volume: 30
Issue: 8
Pages: 2776-2790.e6
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Publication
29540569 | J:261078
First Author: Kuser-Abali G
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: An EZH2-mediated epigenetic mechanism behind p53-dependent tissue sensitivity to DNA damage.
Volume: 115
Issue: 13
Pages: 3452-3457
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Publication
15831521 | J:98536
First Author: Huang W
Year: 2005
Journal: Mol Endocrinol
Title: Xenobiotic stress induces hepatomegaly and liver tumors via the nuclear receptor constitutive androstane receptor.
Volume: 19
Issue: 6
Pages: 1646-53
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Publication
29396424 | J:301795
First Author: Zhao Y
Year: 2018
Journal: Cell Death Dis
Title: Inactivation of ribosomal protein S27-like confers radiosensitivity via the Mdm2-p53 and Mdm2-MRN-ATM axes.
Volume: 9
Issue: 2
Pages: 145
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Publication
23238012 | J:194370
First Author: Lee MK
Year: 2012
Journal: Cancer Cell
Title: Cell-type, dose, and mutation-type specificity dictate mutant p53 functions in vivo.
Volume: 22
Issue: 6
Pages: 751-64
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Publication
33303641 | J:314680
First Author: Kon N
Year: 2021
Journal: Genes Dev
Title: mTOR inhibition acts as an unexpected checkpoint in p53-mediated tumor suppression.
Volume: 35
Issue: 1-2
Pages: 59-64
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Publication
10973245 | J:64367
First Author: Jimenez GS
Year: 2000
Journal: Nat Genet
Title: A transactivation-deficient mouse model provides insights into Trp53 regulation and function.
Volume: 26
Issue: 1
Pages: 37-43
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Publication
24722541 | J:210515
 
First Author: Munne PM
Year: 2014
Journal: Sci Rep
Title: TP53 supports basal-like differentiation of mammary epithelial cells by preventing translocation of deltaNp63 into nucleoli.
Volume: 4
Pages: 4663
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Publication
36952348 | J:334480
First Author: Hu H
Year: 2023
Journal: Cell Rep
Title: The RNA binding protein RALY suppresses p53 activity and promotes lung tumorigenesis.
Volume: 42
Issue: 4
Pages: 112288
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Publication
10710310 | J:60946
First Author: Hirao A
Year: 2000
Journal: Science
Title: DNA damage-induced activation of p53 by the checkpoint kinase Chk2.
Volume: 287
Issue: 5459
Pages: 1824-7
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Publication
18952844 | J:248238
First Author: Cai X
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Inhibition of Thr-55 phosphorylation restores p53 nuclear localization and sensitizes cancer cells to DNA damage.
Volume: 105
Issue: 44
Pages: 16958-63
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Publication
18485870 | J:159136
First Author: Tang Y
Year: 2008
Journal: Cell
Title: Acetylation is indispensable for p53 activation.
Volume: 133
Issue: 4
Pages: 612-26
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Publication
11404026 | J:70147
First Author: Parant JM
Year: 2001
Journal: Gene
Title: Organization, expression, and localization of the murine mdmx gene and pseudogene.
Volume: 270
Issue: 1-2
Pages: 277-83
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Publication
11577350 | J:71978
First Author: Stanislawski T
Year: 2001
Journal: Nat Immunol
Title: Circumventing tolerance to a human MDM2-derived tumor antigen by TCR gene transfer.
Volume: 2
Issue: 10
Pages: 962-70
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Publication
9226370 | J:41655
First Author: Shvarts A
Year: 1997
Journal: Genomics
Title: Isolation and identification of the human homolog of a new p53-binding protein, Mdmx.
Volume: 43
Issue: 1
Pages: 34-42
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Publication
9738462 | J:49797
First Author: Guerra B
Year: 1998
Journal: FEBS Lett
Title: p53 and the ribosomal protein L5 participate in high molecular mass complex formation with protein kinase CK2 in murine teratocarcinoma cell line F9 after serum stimulation and cisplatin treatment.
Volume: 434
Issue: 1-2
Pages: 115-20
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Publication
14707286 | J:87254
First Author: Ganguli G
Year: 2003
Journal: Mol Cancer Res
Title: p53-independent functions of MDM2.
Volume: 1
Issue: 14
Pages: 1027-35
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Publication
15452548 | J:93374
First Author: Klein C
Year: 2004
Journal: Br J Cancer
Title: Targeting the p53-MDM2 interaction to treat cancer.
Volume: 91
Issue: 8
Pages: 1415-9
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Publication
15975924 | J:101052
First Author: Yamashita M
Year: 2005
Journal: J Biol Chem
Title: Ras-ERK MAPK cascade regulates GATA3 stability and Th2 differentiation through ubiquitin-proteasome pathway.
Volume: 280
Issue: 33
Pages: 29409-19
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Publication
16704373 | J:116449
First Author: Sánchez-Molina S
Year: 2006
Journal: Biochem J
Title: The histone acetyltransferases CBP/p300 are degraded in NIH 3T3 cells by activation of Ras signalling pathway.
Volume: 398
Issue: 2
Pages: 215-24
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Publication
17251377 | J:120770
First Author: Marine JC
Year: 2007
Journal: J Cell Sci
Title: MDMX: from bench to bedside.
Volume: 120
Issue: Pt 3
Pages: 371-8
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Publication
18381074 | J:134262
First Author: Ueda Y
Year: 2008
Journal: FEBS Lett
Title: Small mitochondrial ARF (smARF) is located in both the nucleus and cytoplasm, induces cell death, and activates p53 in mouse fibroblasts.
Volume: 582
Issue: 10
Pages: 1459-64
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Publication
17846171 | J:134796
First Author: Xiong L
Year: 2007
Journal: J Cell Biol
Title: A novel role for IGF-1R in p53-mediated apoptosis through translational modulation of the p53-Mdm2 feedback loop.
Volume: 178
Issue: 6
Pages: 995-1007
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Publication
22431589 | J:182657
First Author: Suh SS
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: MicroRNAs/TP53 feedback circuitry in glioblastoma multiforme.
Volume: 109
Issue: 14
Pages: 5316-21
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Publication
25477334 | J:217526
First Author: Meng X
Year: 2014
Journal: Cancer Res
Title: MDM2-p53 pathway in hepatocellular carcinoma.
Volume: 74
Issue: 24
Pages: 7161-7
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Publication
28837860 | J:249738
 
First Author: Liu S
Year: 2017
Journal: Neurobiol Aging
Title: Pomegranate peel extract attenuates D-galactose-induced oxidative stress and hearing loss by regulating PNUTS/PP1 activity in the mouse cochlea.
Volume: 59
Pages: 30-40
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Publication
33431824 | J:300982
First Author: Latif AL
Year: 2021
Journal: Nat Commun
Title: BRD4-mediated repression of p53 is a target for combination therapy in AML.
Volume: 12
Issue: 1
Pages: 241
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Publication
22157679 | J:317305
First Author: Amson R
Year: 2011
Journal: Nat Med
Title: Reciprocal repression between P53 and TCTP.
Volume: 18
Issue: 1
Pages: 91-9
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Publication
26904937 | J:316557
First Author: Valente LJ
Year: 2016
Journal: Cell Rep
Title: Therapeutic Response to Non-genotoxic Activation of p53 by Nutlin3a Is Driven by PUMA-Mediated Apoptosis in Lymphoma Cells.
Volume: 14
Issue: 8
Pages: 1858-66
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Publication
35105861 | J:320238
First Author: Khadka P
Year: 2022
Journal: Nat Commun
Title: PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation.
Volume: 13
Issue: 1
Pages: 604
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Publication
8910340 | J:36914
First Author: Datta B
Year: 1996
Journal: J Biol Chem
Title: p202, an interferon-inducible modulator of transcription, inhibits transcriptional activation by the p53 tumor suppressor protein, and a segment from the p53-binding protein 1 that binds to p202 overcomes this inhibition.
Volume: 271
Issue: 44
Pages: 27544-55
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Publication
20080757 | J:156522
First Author: Ramachandran S
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: The RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombination.
Volume: 107
Issue: 2
Pages: 809-14
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Publication
15735665 | J:98384
First Author: Lin L
Year: 2005
Journal: Oncogene
Title: topors, a p53 and topoisomerase I-binding RING finger protein, is a coactivator of p53 in growth suppression induced by DNA damage.
Volume: 24
Issue: 21
Pages: 3385-96
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Publication
17906694 | J:135509
First Author: Iwakuma T
Year: 2008
Journal: Oncogene
Title: Mtbp haploinsufficiency in mice increases tumor metastasis.
Volume: 27
Issue: 13
Pages: 1813-20
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Publication
16219768 | J:105906
First Author: Chang NS
Year: 2005
Journal: J Biol Chem
Title: WOX1 is essential for tumor necrosis factor-, UV light-, staurosporine-, and p53-mediated cell death, and its tyrosine 33-phosphorylated form binds and stabilizes serine 46-phosphorylated p53.
Volume: 280
Issue: 52
Pages: 43100-8
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Publication
26471359 | J:226765
First Author: Sun Y
Year: 2015
Journal: Cancer Res
Title: WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma.
Volume: 75
Issue: 23
Pages: 5143-54
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Publication
30213853 | J:265919
First Author: Singh HP
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Developmental stage-specific proliferation and retinoblastoma genesis in RB-deficient human but not mouse cone precursors.
Volume: 115
Issue: 40
Pages: E9391-E9400
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Publication
11431698 | J:70271
First Author: Xu X
Year: 2001
Journal: Nat Genet
Title: Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis.
Volume: 28
Issue: 3
Pages: 266-71
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Publication
9207798 | J:41254
First Author: Hakem R
Year: 1997
Journal: Nat Genet
Title: Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation.
Volume: 16
Issue: 3
Pages: 298-302
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Publication
28652370 | J:244260
First Author: van Oosterwijk JG
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Small mitochondrial Arf (smArf) protein corrects p53-independent developmental defects of Arf tumor suppressor-deficient mice.
Volume: 114
Issue: 28
Pages: 7420-7425
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Publication
10541552 | J:58292
First Author: Eischen CM
Year: 1999
Journal: Genes Dev
Title: Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis.
Volume: 13
Issue: 20
Pages: 2658-69
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Publication
21986948 | J:315799
First Author: Sugihara E
Year: 2012
Journal: Oncogene
Title: Ink4a and Arf are crucial factors in the determination of the cell of origin and the therapeutic sensitivity of Myc-induced mouse lymphoid tumor.
Volume: 31
Issue: 23
Pages: 2849-61
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11604501 | J:72281
First Author: Eischen CM
Year: 2001
Journal: Mol Cell Biol
Title: Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis.
Volume: 21
Issue: 22
Pages: 7653-62
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Publication
16037818 | J:101016
First Author: Silva RL
Year: 2005
Journal: EMBO J
Title: Arf-dependent regulation of Pdgf signaling in perivascular cells in the developing mouse eye.
Volume: 24
Issue: 15
Pages: 2803-14
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Publication
20008789 | J:157728
First Author: Ta VB
Year: 2010
Journal: Blood
Title: Malignant transformation of Slp65-deficient pre-B cells involves disruption of the Arf-Mdm2-p53 tumor suppressor pathway.
Volume: 115
Issue: 7
Pages: 1385-93
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Publication
21983037 | J:178850
First Author: Suh YA
Year: 2011
Journal: Cancer Res
Title: Multiple stress signals activate mutant p53 in vivo.
Volume: 71
Issue: 23
Pages: 7168-75
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Publication
35881792 | J:332795
First Author: Falcon KT
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Dynamic regulation and requirement for ribosomal RNA transcription during mammalian development.
Volume: 119
Issue: 31
Pages: e2116974119
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Publication
17943659 | J:134886
First Author: Morrison JP
Year: 2007
Journal: Toxicol Pathol
Title: N-ethyl-N-nitrosourea (ENU)-induced meningiomatosis and meningioma in p16(INK4a)/p19(ARF) tumor suppressor gene-deficient mice.
Volume: 35
Issue: 6
Pages: 780-7
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Publication
32820269 | J:303978
First Author: Aoyama K
Year: 2021
Journal: Leukemia
Title: PRC2 insufficiency causes p53-dependent dyserythropoiesis in myelodysplastic syndrome.
Volume: 35
Issue: 4
Pages: 1156-1165
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Publication
15210712 | J:92528
First Author: Carstens MJ
Year: 2004
Journal: J Biol Chem
Title: Cell cycle arrest and cell death are controlled by p53-dependent and p53-independent mechanisms in Tsg101-deficient cells.
Volume: 279
Issue: 34
Pages: 35984-94
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Publication
31480519 | J:280281
 
First Author: Han NR
Year: 2019
Journal: J Clin Med
Title: TSLP Exacerbates Septic Inflammation via Murine Double Minute 2 (MDM2) Signaling Pathway.
Volume: 8
Issue: 9
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Publication
29709619 | J:277525
 
First Author: Si S
Year: 2018
Journal: Exp Hematol
Title: Hematopoietic insults damage bone marrow niche by activating p53 in vascular endothelial cells.
Volume: 63
Pages: 41-51.e1
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Publication
34465864 | J:320936
First Author: Yuan S
Year: 2022
Journal: Leukemia
Title: PHF6 and JAK3 mutations cooperate to drive T-cell acute lymphoblastic leukemia progression.
Volume: 36
Issue: 2
Pages: 370-382
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Publication
29581299 | J:261424
First Author: Huang Q
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: MDMX acidic domain inhibits p53 DNA binding in vivo and regulates tumorigenesis.
Volume: 115
Issue: 15
Pages: E3368-E3377
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Publication
24480804 | J:212505
First Author: Schneeberger VE
Year: 2014
Journal: Carcinogenesis
Title: SHP2E76K mutant promotes lung tumorigenesis in transgenic mice.
Volume: 35
Issue: 8
Pages: 1717-25
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Publication
27528230 | J:252045
First Author: Cubillos-Rojas M
Year: 2016
Journal: Oncotarget
Title: The HERC2 ubiquitin ligase is essential for embryonic development and regulates motor coordination.
Volume: 7
Issue: 35
Pages: 56083-56106
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Publication
30262665 | J:272817
First Author: Wang J
Year: 2018
Journal: J Biol Chem
Title: Protein phosphatase 5 and the tumor suppressor p53 down-regulate each other's activities in mice.
Volume: 293
Issue: 47
Pages: 18218-18229
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Publication
33495326 | J:302580
 
First Author: Ianni A
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: SIRT7-dependent deacetylation of NPM promotes p53 stabilization following UV-induced genotoxic stress.
Volume: 118
Issue: 5
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Publication
22187431 | J:182446
First Author: Kon N
Year: 2012
Journal: J Biol Chem
Title: Inactivation of arf-bp1 induces p53 activation and diabetic phenotypes in mice.
Volume: 287
Issue: 7
Pages: 5102-11
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Publication
31092600 | J:280720
First Author: Xu Y
Year: 2019
Journal: J Biol Chem
Title: Prolyl hydroxylase 3 stabilizes the p53 tumor suppressor by inhibiting the p53-MDM2 interaction in a hydroxylase-independent manner.
Volume: 294
Issue: 25
Pages: 9949-9958
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Publication
19884656 | J:155109
First Author: Ghosh M
Year: 2009
Journal: J Clin Invest
Title: Essential role of the RNA-binding protein HuR in progenitor cell survival in mice.
Volume: 119
Issue: 12
Pages: 3530-43
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27065327 | J:237931
First Author: Pant V
Year: 2016
Journal: Oncogene
Title: Distinct downstream targets manifest p53-dependent pathologies in mice.
Volume: 35
Issue: 44
Pages: 5713-5721
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Publication
25393878 | J:225146
First Author: Reed SM
Year: 2014
Journal: PLoS One
Title: NIAM-deficient mice are predisposed to the development of proliferative lesions including B-cell lymphomas.
Volume: 9
Issue: 11
Pages: e112126
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Publication
28460439 | J:256595
First Author: Pant V
Year: 2017
Journal: Oncotarget
Title: Tumorigenesis promotes Mdm4-S overexpression.
Volume: 8
Issue: 16
Pages: 25837-25847
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Publication
21563203 | J:264725
First Author: Tarocchi M
Year: 2011
Journal: Hepatology
Title: Carcinogen-induced hepatic tumors in KLF6+/- mice recapitulate aggressive human hepatocellular carcinoma associated with p53 pathway deregulation.
Volume: 54
Issue: 2
Pages: 522-31
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Publication
33801773 | J:327795
 
First Author: Lam B
Year: 2021
Journal: Cells
Title: High Glucose Treatment Limits Drosha Protein Expression and Alters AngiomiR Maturation in Microvascular Primary Endothelial Cells via an Mdm2-dependent Mechanism.
Volume: 10
Issue: 4
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Publication
29523541 | J:262585
First Author: Li D
Year: 2018
Journal: Cancer Res
Title: Peli1 Modulates the Subcellular Localization and Activity of Mdmx.
Volume: 78
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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