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Search results 1 to 100 out of 135 for Ext1

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Category: Publication
Type Details Score
Publication
First Author: McCormick C
Year: 1998
Journal: Nat Genet
Title: The putative tumour suppressor EXT1 alters the expression of cell-surface heparan sulfate.
Volume: 19
Issue: 2
Pages: 158-61
Publication
First Author: Yamada S
Year: 2004
Journal: J Biol Chem
Title: Embryonic fibroblasts with a gene trap mutation in Ext1 produce short heparan sulfate chains.
Volume: 279
Issue: 31
Pages: 32134-41
Publication
First Author: Hilton MJ
Year: 2005
Journal: Bone
Title: EXT1 regulates chondrocyte proliferation and differentiation during endochondral bone development.
Volume: 36
Issue: 3
Pages: 379-86
Publication
First Author: Osterholm C
Year: 2009
Journal: J Biol Chem
Title: Mutation in the heparan sulfate biosynthesis enzyme EXT1 influences growth factor signaling and fibroblast interactions with the extracellular matrix.
Volume: 284
Issue: 50
Pages: 34935-43
Publication
First Author: Wei G
Year: 2000
Journal: J Biol Chem
Title: Location of the glucuronosyltransferase domain in the heparan sulfate copolymerase EXT1 by analysis of Chinese hamster ovary cell mutants.
Volume: 275
Issue: 36
Pages: 27733-40
Publication
First Author: Inatani M
Year: 2003
Journal: Brain Res Dev Brain Res
Title: Gene expression of EXT1 and EXT2 during mouse brain development.
Volume: 141
Issue: 1-2
Pages: 129-36
Publication
First Author: Jones KB
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: A mouse model of osteochondromagenesis from clonal inactivation of Ext1 in chondrocytes.
Volume: 107
Issue: 5
Pages: 2054-9
Publication
First Author: Lin X
Year: 1997
Journal: DNA Seq
Title: Isolation of the mouse cDNA homologous to the human EXT1 gene responsible for Hereditary Multiple Exostoses.
Volume: 7
Issue: 3-4
Pages: 199-202
Publication
First Author: O'Hearn A
Year: 2015
Journal: J Virol
Title: Role of EXT1 and Glycosaminoglycans in the Early Stage of Filovirus Entry.
Volume: 89
Issue: 10
Pages: 5441-9
Publication
First Author: McCormick C
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: The putative tumor suppressors EXT1 and EXT2 form a stable complex that accumulates in the Golgi apparatus and catalyzes the synthesis of heparan sulfate.
Volume: 97
Issue: 2
Pages: 668-73
Publication      
First Author: Sheffield VC
Year: 2009
Journal: MGI Direct Data Submission
Title: Generation of a floxed allele of Ext1
Publication
First Author: Hecht JT
Year: 1997
Journal: Am J Hum Genet
Title: Hereditary multiple exostoses (EXT): mutational studies of familial EXT1 cases and EXT-associated malignancies.
Volume: 60
Issue: 1
Pages: 80-6
Publication
First Author: Mooij HL
Year: 2015
Journal: J Lipid Res
Title: Ext1 heterozygosity causes a modest effect on postprandial lipid clearance in humans.
Volume: 56
Issue: 3
Pages: 665-73
Publication
First Author: Presto J
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Heparan sulfate biosynthesis enzymes EXT1 and EXT2 affect NDST1 expression and heparan sulfate sulfation.
Volume: 105
Issue: 12
Pages: 4751-6
Publication
First Author: de Andrea CE
Year: 2015
Journal: J Pathol
Title: Cell cycle deregulation and mosaic loss of Ext1 drive peripheral chondrosarcomagenesis in the mouse and reveal an intrinsic cilia deficiency.
Volume: 236
Issue: 2
Pages: 210-8
Publication
First Author: Zak BM
Year: 2011
Journal: Bone
Title: Compound heterozygous loss of Ext1 and Ext2 is sufficient for formation of multiple exostoses in mouse ribs and long bones.
Volume: 48
Issue: 5
Pages: 979-87
Publication
First Author: Lohmann DR
Year: 1997
Journal: Cytogenet Cell Genet
Title: The murine Ext1 gene shows a high level of sequence similarity with its human homologue and is part of a conserved linkage group on chromosome 15.
Volume: 76
Issue: 3-4
Pages: 164-6
Publication
First Author: Mundy C
Year: 2011
Journal: Dev Biol
Title: Synovial joint formation requires local Ext1 expression and heparan sulfate production in developing mouse embryo limbs and spine.
Volume: 351
Issue: 1
Pages: 70-81
Publication
First Author: Matsumoto K
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: A mouse model of chondrocyte-specific somatic mutation reveals a role for Ext1 loss of heterozygosity in multiple hereditary exostoses.
Volume: 107
Issue: 24
Pages: 10932-7
Publication
First Author: Matsumoto Y
Year: 2010
Journal: J Biol Chem
Title: Conditional ablation of the heparan sulfate-synthesizing enzyme Ext1 leads to dysregulation of bone morphogenic protein signaling and severe skeletal defects.
Volume: 285
Issue: 25
Pages: 19227-34
Publication
First Author: Mooij HL
Year: 2014
Journal: J Am Heart Assoc
Title: Loss of function in heparan sulfate elongation genes EXT1 and EXT 2 results in improved nitric oxide bioavailability and endothelial function.
Volume: 3
Issue: 6
Pages: e001274
Publication
First Author: Huegel J
Year: 2013
Journal: Dev Biol
Title: Perichondrium phenotype and border function are regulated by Ext1 and heparan sulfate in developing long bones: a mechanism likely deranged in Hereditary Multiple Exostoses.
Volume: 377
Issue: 1
Pages: 100-12
Publication
First Author: Ohkawa Y
Year: 2021
Journal: Mol Cancer Res
Title: Heparan Sulfate Synthesized by Ext1 Regulates Receptor Tyrosine Kinase Signaling and Promotes Resistance to EGFR Inhibitors in GBM.
Volume: 19
Issue: 1
Pages: 150-161
Publication
First Author: Jones KB
Year: 2013
Journal: J Orthop Res
Title: Toward an understanding of the short bone phenotype associated with multiple osteochondromas.
Volume: 31
Issue: 4
Pages: 651-7
Publication
First Author: Koziel L
Year: 2004
Journal: Dev Cell
Title: Ext1-dependent heparan sulfate regulates the range of Ihh signaling during endochondral ossification.
Volume: 6
Issue: 6
Pages: 801-13
Publication
First Author: Liu CC
Year: 2016
Journal: Sci Transl Med
Title: Neuronal heparan sulfates promote amyloid pathology by modulating brain amyloid-β clearance and aggregation in Alzheimer's disease.
Volume: 8
Issue: 332
Pages: 332ra44
Publication
First Author: Brestoff JR
Year: 2021
Journal: Cell Metab
Title: Intercellular Mitochondria Transfer to Macrophages Regulates White Adipose Tissue Homeostasis and Is Impaired in Obesity.
Volume: 33
Issue: 2
Pages: 270-282.e8
Publication
First Author: Sinha S
Year: 2017
Journal: PLoS Genet
Title: Unsuspected osteochondroma-like outgrowths in the cranial base of Hereditary Multiple Exostoses patients and modeling and treatment with a BMP antagonist in mice.
Volume: 13
Issue: 4
Pages: e1006742
Publication
First Author: Lin X
Year: 1998
Journal: Biochem Biophys Res Commun
Title: Expression and functional analysis of mouse EXT1, a homolog of the human multiple exostoses type 1 gene.
Volume: 248
Issue: 3
Pages: 738-43
Publication
First Author: Saez B
Year: 2014
Journal: Blood
Title: Inhibiting stromal cell heparan sulfate synthesis improves stem cell mobilization and enables engraftment without cytotoxic conditioning.
Volume: 124
Issue: 19
Pages: 2937-47
Publication
First Author: Mahalingam Y
Year: 2007
Journal: J Biol Chem
Title: Cellular adhesion responses to the heparin-binding (HepII) domain of fibronectin require heparan sulfate with specific properties.
Volume: 282
Issue: 5
Pages: 3221-30
Publication  
First Author: Piombo V
Year: 2018
Journal: Bone
Title: Signaling systems affecting the severity of multiple osteochondromas.
Volume: 111
Pages: 71-81
Publication    
First Author: Hsu HP
Year: 2021
Journal: J Biol Chem
Title: Heparan sulfate is essential for thymus growth.
Pages: 100419
Publication
First Author: Chen S
Year: 2008
Journal: Kidney Int
Title: Loss of heparan sulfate glycosaminoglycan assembly in podocytes does not lead to proteinuria.
Volume: 74
Issue: 3
Pages: 289-99
Publication  
First Author: Inubushi T
Year: 2017
Journal: JCI Insight
Title: Aberrant perichondrial BMP signaling mediates multiple osteochondromagenesis in mice.
Volume: 2
Issue: 15
Publication
First Author: Matsuzawa T
Year: 2021
Journal: J Biol Chem
Title: Heparan sulfate promotes differentiation of white adipocytes to maintain insulin sensitivity and glucose homeostasis.
Volume: 297
Issue: 3
Pages: 101006
Publication
First Author: Matsuzawa T
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Heparan sulfate in pancreatic β-cells contributes to normal glucose homeostasis by regulating insulin secretion.
Volume: 499
Issue: 3
Pages: 688-695
Publication
First Author: Inatani M
Year: 2003
Journal: Science
Title: Mammalian brain morphogenesis and midline axon guidance require heparan sulfate.
Volume: 302
Issue: 5647
Pages: 1044-6
Publication
First Author: Kawashima K
Year: 2020
Journal: Osteoarthritis Cartilage
Title: Heparan sulfate deficiency leads to hypertrophic chondrocytes by increasing bone morphogenetic protein signaling.
Volume: 28
Issue: 11
Pages: 1459-1470
Publication
First Author: Okada M
Year: 2010
Journal: Biochem J
Title: Biosynthesis of heparan sulfate in EXT1-deficient cells.
Volume: 428
Issue: 3
Pages: 463-71
Publication
First Author: Sgariglia F
Year: 2013
Journal: Bone
Title: Epiphyseal abnormalities, trabecular bone loss and articular chondrocyte hypertrophy develop in the long bones of postnatal Ext1-deficient mice.
Volume: 57
Issue: 1
Pages: 220-31
Publication
First Author: Zaiss AK
Year: 2015
Journal: J Virol
Title: Hepatocyte Heparan Sulfate Is Required for Adeno-Associated Virus 2 but Dispensable for Adenovirus 5 Liver Transduction In Vivo.
Volume: 90
Issue: 1
Pages: 412-20
Publication
First Author: Stickens D
Year: 2000
Journal: Dev Dyn
Title: EXT genes are differentially expressed in bone and cartilage during mouse embryogenesis.
Volume: 218
Issue: 3
Pages: 452-64
Publication
First Author: Coulson-Thomas VJ
Year: 2015
Journal: Invest Ophthalmol Vis Sci
Title: Loss of corneal epithelial heparan sulfate leads to corneal degeneration and impaired wound healing.
Volume: 56
Issue: 5
Pages: 3004-14
Publication
First Author: Lin X
Year: 2000
Journal: Dev Biol
Title: Disruption of gastrulation and heparan sulfate biosynthesis in EXT1-deficient mice.
Volume: 224
Issue: 2
Pages: 299-311
Publication
First Author: Nadanaka S
Year: 2008
Journal: J Biol Chem
Title: Chondroitin 4-O-sulfotransferase-1 modulates Wnt-3a signaling through control of E disaccharide expression of chondroitin sulfate.
Volume: 283
Issue: 40
Pages: 27333-43
Publication
First Author: Busse M
Year: 2007
Journal: J Biol Chem
Title: Contribution of EXT1, EXT2, and EXTL3 to heparan sulfate chain elongation.
Volume: 282
Issue: 45
Pages: 32802-10
Publication
First Author: Kraushaar DC
Year: 2012
Journal: J Biol Chem
Title: Heparan sulfate facilitates FGF and BMP signaling to drive mesoderm differentiation of mouse embryonic stem cells.
Volume: 287
Issue: 27
Pages: 22691-700
Publication
First Author: Garner OB
Year: 2011
Journal: Dev Biol
Title: Stage-dependent regulation of mammary ductal branching by heparan sulfate and HGF-cMet signaling.
Volume: 355
Issue: 2
Pages: 394-403
Publication  
First Author: Bachvarova V
Year: 2020
Journal: Matrix Biol
Title: Chondrocytes respond to an altered heparan sulfate composition with distinct changes of heparan sulfate structure and increased levels of chondroitin sulfate.
Volume: 93
Pages: 43-59
Publication
First Author: Matsumoto Y
Year: 2007
Journal: J Neurosci
Title: Netrin-1/DCC signaling in commissural axon guidance requires cell-autonomous expression of heparan sulfate.
Volume: 27
Issue: 16
Pages: 4342-50
Publication
First Author: Iwao K
Year: 2010
Journal: Exp Eye Res
Title: Heparan sulfate deficiency in periocular mesenchyme causes microphthalmia and ciliary body dysgenesis.
Volume: 90
Issue: 1
Pages: 81-8
Publication
First Author: Zhang R
Year: 2015
Journal: PLoS One
Title: Heparan Sulfate Biosynthesis Enzyme, Ext1, Contributes to Outflow Tract Development of Mouse Heart via Modulation of FGF Signaling.
Volume: 10
Issue: 8
Pages: e0136518
Publication  
First Author: Huang M
Year: 2018
Journal: J Cell Sci
Title: Multiple roles of epithelial heparan sulfate in stomach morphogenesis.
Volume: 131
Issue: 10
Publication
First Author: He H
Year: 2017
Journal: PLoS Genet
Title: Epithelial heparan sulfate regulates Sonic Hedgehog signaling in lung development.
Volume: 13
Issue: 8
Pages: e1006992
Publication
First Author: Irie F
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Autism-like socio-communicative deficits and stereotypies in mice lacking heparan sulfate.
Volume: 109
Issue: 13
Pages: 5052-6
Publication
First Author: Tsuboi K
Year: 2013
Journal: J Immunol
Title: Role of high endothelial venule-expressed heparan sulfate in chemokine presentation and lymphocyte homing.
Volume: 191
Issue: 1
Pages: 448-55
Publication
First Author: Chen S
Year: 2010
Journal: Kidney Int
Title: Podocytes require the engagement of cell surface heparan sulfate proteoglycans for adhesion to extracellular matrices.
Volume: 78
Issue: 11
Pages: 1088-99
Publication  
First Author: Herrera-Heredia SA
Year: 2022
Journal: Front Immunol
Title: Heparin is required for the formation of granules in connective tissue mast cells.
Volume: 13
Pages: 1000405
Publication
First Author: Coulson-Thomas VJ
Year: 2014
Journal: J Biol Chem
Title: Heparan sulfate regulates hair follicle and sebaceous gland morphogenesis and homeostasis.
Volume: 289
Issue: 36
Pages: 25211-26
Publication
First Author: Nonaka M
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Synthetic di-sulfated iduronic acid attenuates asthmatic response by blocking T-cell recruitment to inflammatory sites.
Volume: 111
Issue: 22
Pages: 8173-8
Publication
First Author: Yamamoto S
Year: 2013
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Heparan sulfate on intestinal epithelial cells plays a critical role in intestinal crypt homeostasis via Wnt/β-catenin signaling.
Volume: 305
Issue: 3
Pages: G241-9
Publication
First Author: Yokoyama M
Year: 2020
Journal: Biochim Biophys Acta Gen Subj
Title: Heparan sulfate controls skeletal muscle differentiation and motor functions.
Volume: 1864
Issue: 12
Pages: 129707
Publication
First Author: Kraushaar DC
Year: 2010
Journal: J Biol Chem
Title: Heparan sulfate is required for embryonic stem cells to exit from self-renewal.
Volume: 285
Issue: 8
Pages: 5907-16
Publication
First Author: Holley RJ
Year: 2011
Journal: J Biol Chem
Title: Influencing hematopoietic differentiation of mouse embryonic stem cells using soluble heparin and heparan sulfate saccharides.
Volume: 286
Issue: 8
Pages: 6241-52
Publication
First Author: Mitchell KJ
Year: 2001
Journal: Nat Genet
Title: Functional analysis of secreted and transmembrane proteins critical to mouse development.
Volume: 28
Issue: 3
Pages: 241-9
Publication  
First Author: Vaahtomeri K
Year: 2021
Journal: Front Immunol
Title: Shape and Function of Interstitial Chemokine CCL21 Gradients Are Independent of Heparan Sulfates Produced by Lymphatic Endothelium.
Volume: 12
Pages: 630002
Publication
First Author: Olde Engberink RHG
Year: 2019
Journal: PLoS One
Title: Abnormal sodium and water homeostasis in mice with defective heparan sulfate polymerization.
Volume: 14
Issue: 7
Pages: e0220333
Publication
First Author: Hennekam RC
Year: 1991
Journal: J Med Genet
Title: Hereditary multiple exostoses.
Volume: 28
Issue: 4
Pages: 262-6
Publication
First Author: Hecht JT
Year: 1995
Journal: Am J Hum Genet
Title: Hereditary multiple exostosis and chondrosarcoma: linkage to chromosome II and loss of heterozygosity for EXT-linked markers on chromosomes II and 8.
Volume: 56
Issue: 5
Pages: 1125-31
Publication  
First Author: Nozawa S
Year: 2018
Journal: JCI Insight
Title: Osteoblastic heparan sulfate regulates osteoprotegerin function and bone mass.
Volume: 3
Issue: 3
Publication
First Author: Bode L
Year: 2008
Journal: J Clin Invest
Title: Heparan sulfate and syndecan-1 are essential in maintaining murine and human intestinal epithelial barrier function.
Volume: 118
Issue: 1
Pages: 229-38
Publication
First Author: Bao X
Year: 2010
Journal: Immunity
Title: Endothelial heparan sulfate controls chemokine presentation in recruitment of lymphocytes and dendritic cells to lymph nodes.
Volume: 33
Issue: 5
Pages: 817-29
Publication
First Author: Stenzel D
Year: 2011
Journal: Development
Title: Integrin-dependent and -independent functions of astrocytic fibronectin in retinal angiogenesis.
Volume: 138
Issue: 20
Pages: 4451-63
Publication
First Author: Garner OB
Year: 2008
Journal: Immunology
Title: Small changes in lymphocyte development and activation in mice through tissue-specific alteration of heparan sulphate.
Volume: 125
Issue: 3
Pages: 420-9
Publication
First Author: Xiong A
Year: 2014
Journal: FEBS J
Title: Heparan sulfate in the regulation of neural differentiation and glioma development.
Volume: 281
Issue: 22
Pages: 4993-5008
Publication
First Author: Le Jan S
Year: 2012
Journal: Arterioscler Thromb Vasc Biol
Title: Functional overlap between chondroitin and heparan sulfate proteoglycans during VEGF-induced sprouting angiogenesis.
Volume: 32
Issue: 5
Pages: 1255-63
Publication
First Author: Xu D
Year: 2011
Journal: J Biol Chem
Title: Heparan sulfate regulates VEGF165- and VEGF121-mediated vascular hyperpermeability.
Volume: 286
Issue: 1
Pages: 737-45
Publication
First Author: Qiu H
Year: 2018
Journal: Nat Methods
Title: A mutant-cell library for systematic analysis of heparan sulfate structure-function relationships.
Volume: 15
Issue: 11
Pages: 889-899
Publication
First Author: Clegg JM
Year: 2019
Journal: J Neurosci
Title: Heparan Sulfate Sulfation by Hs2st Restricts Astroglial Precursor Somal Translocation in Developing Mouse Forebrain by a Non-Cell-Autonomous Mechanism.
Volume: 39
Issue: 8
Pages: 1386-1404
Publication
First Author: Iwao K
Year: 2009
Journal: J Clin Invest
Title: Heparan sulfate deficiency leads to Peters anomaly in mice by disturbing neural crest TGF-beta2 signaling.
Volume: 119
Issue: 7
Pages: 1997-2008
Publication
First Author: Ogata-Iwao M
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Heparan sulfate regulates intraretinal axon pathfinding by retinal ganglion cells.
Volume: 52
Issue: 9
Pages: 6671-9
Publication
First Author: Chan JA
Year: 2009
Journal: Nat Neurosci
Title: Proteoglycan interactions with Sonic Hedgehog specify mitogenic responses.
Volume: 12
Issue: 4
Pages: 409-17
Publication  
First Author: Lowe JB
Year: 2003
Journal: Annu Rev Biochem
Title: A genetic approach to Mammalian glycan function.
Volume: 72
Pages: 643-91
Publication
First Author: Lu T
Year: 2020
Journal: iScience
Title: ADAMTS18 Deficiency Leads to Pulmonary Hypoplasia and Bronchial Microfibril Accumulation.
Volume: 23
Issue: 9
Pages: 101472
Publication  
First Author: Brommage R
Year: 2014
Journal: Bone Res
Title: High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes.
Volume: 2
Pages: 14034
Publication      
First Author: Lexicon Genetics Inc
Year: 2005
Journal: MGI Direct Data Submission
Title: NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: The RIKEN BioResource Center
Year: 2006
Journal: Unpublished
Title: Information obtained from The RIKEN BioResource Center
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer