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Search results 1 to 100 out of 360 for Lmna

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Type Details Score
Publication
24639560 | J:211992
First Author: Lopez-Mejia IC
Year: 2014
Journal: EMBO Rep
Title: Antagonistic functions of LMNA isoforms in energy expenditure and lifespan.
Volume: 15
Issue: 5
Pages: 529-39
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Publication
24203701 | J:207144
First Author: Jung HJ
Year: 2014
Journal: Hum Mol Genet
Title: New Lmna knock-in mice provide a molecular mechanism for the 'segmental aging' in Hutchinson-Gilford progeria syndrome.
Volume: 23
Issue: 6
Pages: 1506-15
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Publication
21875900 | J:177575
First Author: Lopez-Mejia IC
Year: 2011
Journal: Hum Mol Genet
Title: A conserved splicing mechanism of the LMNA gene controls premature aging.
Volume: 20
Issue: 23
Pages: 4540-55
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Publication
22331516 | J:322912
First Author: Poitelon Y
Year: 2012
Journal: Neuromolecular Med
Title: Behavioral and molecular exploration of the AR-CMT2A mouse model Lmna (R298C/R298C).
Volume: 14
Issue: 1
Pages: 40-52
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Publication
17446932 | J:122113
First Author: Muchir A
Year: 2007
Journal: J Clin Invest
Title: Activation of MAPK pathways links LMNA mutations to cardiomyopathy in Emery-Dreifuss muscular dystrophy.
Volume: 117
Issue: 5
Pages: 1282-93
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Publication
23998933 | J:211369
First Author: Kim Y
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Generation and characterization of a conditional deletion allele for Lmna in mice.
Volume: 440
Issue: 1
Pages: 8-13
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Publication
20376364 | J:160175
First Author: Odgren PR
Year: 2010
Journal: PLoS One
Title: Disheveled hair and ear (Dhe), a spontaneous mouse Lmna mutation modeling human laminopathies.
Volume: 5
Issue: 4
Pages: e9959
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Publication
26999604 | J:234711
First Author: Lee JM
Year: 2016
Journal: J Clin Invest
Title: Modulation of LMNA splicing as a strategy to treat prelamin A diseases.
Volume: 126
Issue: 4
Pages: 1592-602
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Publication
15608054 | J:95274
First Author: Fong LG
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Heterozygosity for Lmna deficiency eliminates the progeria-like phenotypes in Zmpste24-deficient mice.
Volume: 101
Issue: 52
Pages: 18111-6
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Publication
21151901 | J:167734
First Author: Lu D
Year: 2010
Journal: PLoS One
Title: LMNA E82K mutation activates FAS and mitochondrial pathways of apoptosis in heart tissue specific transgenic mice.
Volume: 5
Issue: 12
Pages: e15167
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Publication
20388542 | J:165372
First Author: Wu W
Year: 2010
Journal: Biochim Biophys Acta
Title: Pharmacological inhibition of c-Jun N-terminal kinase signaling prevents cardiomyopathy caused by mutation in LMNA gene.
Volume: 1802
Issue: 7-8
Pages: 632-8
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Publication
23430973 | J:199963
First Author: Bertacchini J
Year: 2013
Journal: FASEB J
Title: The protein kinase Akt/PKB regulates both prelamin A degradation and Lmna gene expression.
Volume: 27
Issue: 6
Pages: 2145-55
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Publication
36583724 | J:338760
First Author: Qiu R
Year: 2023
Journal: FASEB J
Title: Mice harboring a R133L heterozygous mutation in LMNA exhibited ectopic lipid accumulation, aging, and mitochondrial dysfunction in adipose tissue.
Volume: 37
Issue: 2
Pages: e22730
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Publication
30696354 | J:292602
First Author: Chen SN
Year: 2019
Journal: Circ Res
Title: DNA Damage Response/TP53 Pathway Is Activated and Contributes to the Pathogenesis of Dilated Cardiomyopathy Associated With LMNA (Lamin A/C) Mutations.
Volume: 124
Issue: 6
Pages: 856-873
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Publication
30342008 | J:270089
 
First Author: Galata Z
Year: 2018
Journal: J Mol Cell Cardiol
Title: Amelioration of desmin network defects by αB-crystallin overexpression confers cardioprotection in a mouse model of dilated cardiomyopathy caused by LMNA gene mutation.
Volume: 125
Pages: 73-86
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Publication
34250035 | J:313164
 
First Author: Onoue K
Year: 2021
Journal: Front Cardiovasc Med
Title: Cardiomyocyte Proliferative Capacity Is Restricted in Mice With Lmna Mutation.
Volume: 8
Pages: 639148
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Publication
16014412 | J:100220
First Author: Yang SH
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Blocking protein farnesyltransferase improves nuclear blebbing in mouse fibroblasts with a targeted Hutchinson-Gilford progeria syndrome mutation.
Volume: 102
Issue: 29
Pages: 10291-6
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Publication
20421363 | J:160705
First Author: Davies BS
Year: 2010
Journal: Hum Mol Genet
Title: An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria.
Volume: 19
Issue: 13
Pages: 2682-94
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Publication
18178963 | J:133791
First Author: Yang SH
Year: 2008
Journal: J Biol Chem
Title: Eliminating the synthesis of mature lamin A reduces disease phenotypes in mice carrying a Hutchinson-Gilford progeria syndrome allele.
Volume: 283
Issue: 11
Pages: 7094-9
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Publication
18082640 | J:133416
First Author: Yang SH
Year: 2008
Journal: Biochim Biophys Acta
Title: Treatment with a farnesyltransferase inhibitor improves survival in mice with a Hutchinson-Gilford progeria syndrome mutation.
Volume: 1781
Issue: 1-2
Pages: 36-9
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Publication
30778239 | J:285478
First Author: Santiago-Fernández O
Year: 2019
Journal: Nat Med
Title: Development of a CRISPR/Cas9-based therapy for Hutchinson-Gilford progeria syndrome.
Volume: 25
Issue: 3
Pages: 423-426
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Publication
25652409 | J:220988
First Author: Yang SH
Year: 2015
Journal: Hum Mol Genet
Title: Mice that express farnesylated versions of prelamin A in neurons develop achalasia.
Volume: 24
Issue: 10
Pages: 2826-40
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Publication
16862216 | J:113119
First Author: Yang SH
Year: 2006
Journal: J Clin Invest
Title: A farnesyltransferase inhibitor improves disease phenotypes in mice with a Hutchinson-Gilford progeria syndrome mutation.
Volume: 116
Issue: 8
Pages: 2115-21
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Publication
31941672 | J:304050
First Author: Heizer PJ
Year: 2020
Journal: J Lipid Res
Title: Deficiency in ZMPSTE24 and resulting farnesyl-prelamin A accumulation only modestly affect mouse adipose tissue stores.
Volume: 61
Issue: 3
Pages: 413-421
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33413510 | J:309036
First Author: Zhou Y
Year: 2021
Journal: J Hematol Oncol
Title: Hepatic NOD2 promotes hepatocarcinogenesis via a RIP2-mediated proinflammatory response and a novel nuclear autophagy-mediated DNA damage mechanism.
Volume: 14
Issue: 1
Pages: 9
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18757838 | J:146099
First Author: Davies BS
Year: 2009
Journal: J Lipid Res
Title: Increasing the length of progerin's isoprenyl anchor does not worsen bone disease or survival in mice with Hutchinson-Gilford progeria syndrome.
Volume: 50
Issue: 1
Pages: 126-34
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Publication
18769635 | J:141165
First Author: Yang SH
Year: 2008
Journal: J Clin Invest
Title: Progerin elicits disease phenotypes of progeria in mice whether or not it is farnesylated.
Volume: 118
Issue: 10
Pages: 3291-300
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Publication
30257952 | J:267010
 
First Author: Kim PH
Year: 2018
Journal: Sci Transl Med
Title: Disrupting the LINC complex in smooth muscle cells reduces aortic disease in a mouse model of Hutchinson-Gilford progeria syndrome.
Volume: 10
Issue: 460
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Publication
19124654 | J:146197
First Author: Méjat A
Year: 2009
Journal: J Cell Biol
Title: Lamin A/C-mediated neuromuscular junction defects in Emery-Dreifuss muscular dystrophy.
Volume: 184
Issue: 1
Pages: 31-44
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Publication
37058558 | J:335522
First Author: Yamada S
Year: 2023
Journal: Sci Adv
Title: TEAD1 trapping by the Q353R-Lamin A/C causes dilated cardiomyopathy.
Volume: 9
Issue: 15
Pages: eade7047
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28674081 | J:263642
First Author: Harhouri K
Year: 2017
Journal: EMBO Mol Med
Title: MG132-induced progerin clearance is mediated by autophagy activation and splicing regulation.
Volume: 9
Issue: 9
Pages: 1294-1313
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Publication
31794718 | J:284191
First Author: Antoku S
Year: 2019
Journal: Dev Cell
Title: ERK1/2 Phosphorylation of FHOD Connects Signaling and Nuclear Positioning Alternations in Cardiac Laminopathy.
Volume: 51
Issue: 5
Pages: 602-616.e12
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Publication
22837537 | J:186774
First Author: Choi JC
Year: 2012
Journal: Sci Transl Med
Title: Temsirolimus activates autophagy and ameliorates cardiomyopathy caused by lamin A/C gene mutation.
Volume: 4
Issue: 144
Pages: 144ra102
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Publication
29982513 | J:267018
First Author: Rodriguez BM
Year: 2018
Journal: Hum Mol Genet
Title: N-acetyl cysteine alleviates oxidative stress and protects mice from dilated cardiomyopathy caused by mutations in nuclear A-type lamins gene.
Volume: 27
Issue: 19
Pages: 3353-3360
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Publication
29878125 | J:264281
First Author: Chatzifrangkeskou M
Year: 2018
Journal: Hum Mol Genet
Title: Cofilin-1 phosphorylation catalyzed by ERK1/2 alters cardiac actin dynamics in dilated cardiomyopathy caused by lamin A/C gene mutation.
Volume: 27
Issue: 17
Pages: 3060-3078
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21498514 | J:173222
First Author: Ahmady E
Year: 2011
Journal: J Biol Chem
Title: Identification of a novel muscle A-type lamin-interacting protein (MLIP).
Volume: 286
Issue: 22
Pages: 19702-13
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29703891 | J:261974
First Author: Balmus G
Year: 2018
Journal: Nat Commun
Title: Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome.
Volume: 9
Issue: 1
Pages: 1700
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Publication
34354059 | J:341821
First Author: Chai RJ
Year: 2021
Journal: Nat Commun
Title: Disrupting the LINC complex by AAV mediated gene transduction prevents progression of Lamin induced cardiomyopathy.
Volume: 12
Issue: 1
Pages: 4722
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Publication
22541428 | J:186197
First Author: Chen CY
Year: 2012
Journal: Cell
Title: Accumulation of the inner nuclear envelope protein Sun1 is pathogenic in progeric and dystrophic laminopathies.
Volume: 149
Issue: 3
Pages: 565-77
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Publication
37515770 | J:339324
First Author: Pruvost M
Year: 2023
Journal: Cell Rep
Title: The stability of the myelinating oligodendrocyte transcriptome is regulated by the nuclear lamina.
Volume: 42
Issue: 8
Pages: 112848
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31833196 | J:284048
First Author: Wang WP
Year: 2020
Journal: Aging Cell
Title: Progerin in muscle leads to thermogenic and metabolic defects via impaired calcium homeostasis.
Volume: 19
Issue: 2
Pages: e13090
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31844279 | J:297781
First Author: Earle AJ
Year: 2020
Journal: Nat Mater
Title: Mutant lamins cause nuclear envelope rupture and DNA damage in skeletal muscle cells.
Volume: 19
Issue: 4
Pages: 464-473
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Publication
34088712 | J:311051
First Author: Corsa CAS
Year: 2021
Journal: Diabetes
Title: Adipocyte-Specific Deletion of Lamin A/C Largely Models Human Familial Partial Lipodystrophy Type 2.
Volume: 70
Issue: 9
Pages: 1970-1984
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Publication
21364987 | J:171065
First Author: Gnocchi VF
Year: 2011
Journal: PLoS One
Title: Uncoordinated transcription and compromised muscle function in the lmna-null mouse model of Emery- Emery-Dreyfuss muscular dystrophy.
Volume: 6
Issue: 2
Pages: e16651
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Publication
32313136 | J:289807
First Author: Shao Z
Year: 2020
Journal: Sci Rep
Title: RNA Sequence Analyses throughout the Course of Mouse Cardiac Laminopathy Identify Differentially Expressed Genes for Cell Cycle Control and Mitochondrial Function.
Volume: 10
Issue: 1
Pages: 6632
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22819531 | J:188496
First Author: Zhang Y
Year: 2012
Journal: Am J Pathol
Title: Pathological features in the LmnaDhe/+ mutant mouse provide a novel model of human otitis media and laminopathies.
Volume: 181
Issue: 3
Pages: 761-74
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12748643 | J:83382
First Author: Mounkes LC
Year: 2003
Journal: Nature
Title: A progeroid syndrome in mice is caused by defects in A-type lamins.
Volume: 423
Issue: 6937
Pages: 298-301
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30053027 | J:267204
First Author: Vignier N
Year: 2018
Journal: Hum Mol Genet
Title: Rescue of biosynthesis of nicotinamide adenine dinucleotide protects the heart in cardiomyopathy caused by lamin A/C gene mutation.
Volume: 27
Issue: 22
Pages: 3870-3880
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Publication
22068161 | J:194873
First Author: Muchir A
Year: 2012
Journal: Cardiovasc Res
Title: Treatment with selumetinib preserves cardiac function and improves survival in cardiomyopathy caused by mutation in the lamin A/C gene.
Volume: 93
Issue: 2
Pages: 311-9
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15972724 | J:100393
First Author: Mounkes LC
Year: 2005
Journal: Hum Mol Genet
Title: Expression of an LMNA-N195K variant of A-type lamins results in cardiac conduction defects and death in mice.
Volume: 14
Issue: 15
Pages: 2167-80
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23575224 | J:198526
First Author: Cattin ME
Year: 2013
Journal: Hum Mol Genet
Title: Heterozygous LmnadelK32 mice develop dilated cardiomyopathy through a combined pathomechanism of haploinsufficiency and peptide toxicity.
Volume: 22
Issue: 15
Pages: 3152-64
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21818413 | J:221850
First Author: Kubben N
Year: 2011
Journal: Nucleus
Title: Post-natal myogenic and adipogenic developmental: defects and metabolic impairment upon loss of A-type lamins.
Volume: 2
Issue: 3
Pages: 195-207
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21173262 | J:169002
First Author: Folker ES
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Lamin A variants that cause striated muscle disease are defective in anchoring transmembrane actin-associated nuclear lines for nuclear movement.
Volume: 108
Issue: 1
Pages: 131-6
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20405040 | J:160149
First Author: Hale JS
Year: 2010
Journal: PLoS One
Title: Cell-extrinsic defective lymphocyte development in Lmna(-/-) mice.
Volume: 5
Issue: 4
Pages: e10127
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11855819 | J:75101
First Author: Cutler DA
Year: 2002
Journal: Biochem Biophys Res Commun
Title: Characterization of adiposity and metabolism in Lmna-deficient mice.
Volume: 291
Issue: 3
Pages: 522-7
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18182166 | J:131905
First Author: Wolf CM
Year: 2008
Journal: J Mol Cell Cardiol
Title: Lamin A/C haploinsufficiency causes dilated cardiomyopathy and apoptosis-triggered cardiac conduction system disease.
Volume: 44
Issue: 2
Pages: 293-303
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18442998 | J:137663
First Author: Wang Y
Year: 2008
Journal: Hum Mol Genet
Title: Epidermal expression of the truncated prelamin A causing Hutchinson-Gilford progeria syndrome: effects on keratinocytes, hair and skin.
Volume: 17
Issue: 15
Pages: 2357-69
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20019332 | J:170882
First Author: Chandar S
Year: 2010
Journal: Circ Res
Title: Effects of mechanical stress and carvedilol in lamin A/C-deficient dilated cardiomyopathy.
Volume: 106
Issue: 3
Pages: 573-82
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27617860 | J:237382
First Author: Lee SJ
Year: 2016
Journal: J Clin Invest
Title: Interruption of progerin-lamin A/C binding ameliorates Hutchinson-Gilford progeria syndrome phenotype.
Volume: 126
Issue: 10
Pages: 3879-3893
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37354210 | J:338110
First Author: Wilkie SE
Year: 2023
Journal: Aging (Albany NY)
Title: Hepatic hydrogen sulfide levels are reduced in mouse model of Hutchinson-Gilford progeria syndrome.
Volume: 15
Issue: 12
Pages: 5266-5278
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22030750 | J:177632
First Author: Osorio FG
Year: 2011
Journal: Sci Transl Med
Title: Splicing-directed therapy in a new mouse model of human accelerated aging.
Volume: 3
Issue: 106
Pages: 106ra107
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32244403 | J:337051
 
First Author: Bertrand AT
Year: 2020
Journal: Cells
Title: Lamin A/C Assembly Defects in LMNA-Congenital Muscular Dystrophy Is Responsible for the Increased Severity of the Disease Compared with Emery-Dreifuss Muscular Dystrophy.
Volume: 9
Issue: 4
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24153156 | J:317656
First Author: Das A
Year: 2013
Journal: Nucleus
Title: Lamin A Δexon9 mutation leads to telomere and chromatin defects but not genomic instability.
Volume: 4
Issue: 5
Pages: 410-9
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15548545 | J:95528
First Author: Arimura T
Year: 2005
Journal: Hum Mol Genet
Title: Mouse model carrying H222P-Lmna mutation develops muscular dystrophy and dilated cardiomyopathy similar to human striated muscle laminopathies.
Volume: 14
Issue: 1
Pages: 155-69
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18927124 | J:143589
First Author: Muchir A
Year: 2009
Journal: Hum Mol Genet
Title: Inhibition of extracellular signal-regulated kinase signaling to prevent cardiomyopathy caused by mutation in the gene encoding A-type lamins.
Volume: 18
Issue: 2
Pages: 241-7
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29893868 | J:285215
First Author: Macquart C
Year: 2019
Journal: Hum Mol Genet
Title: Microtubule cytoskeleton regulates Connexin 43 localization and cardiac conduction in cardiomyopathy caused by mutation in A-type lamins gene.
Volume: 28
Issue: 24
Pages: 4043-4052
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23048029 | J:192633
First Author: Choi JC
Year: 2012
Journal: J Biol Chem
Title: Dual specificity phosphatase 4 mediates cardiomyopathy caused by lamin A/C (LMNA) gene mutation.
Volume: 287
Issue: 48
Pages: 40513-24
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32005707 | J:286987
First Author: de Toledo M
Year: 2020
Journal: Diabetes
Title: Lamin C Counteracts Glucose Intolerance in Aging, Obesity, and Diabetes Through β-Cell Adaptation.
Volume: 69
Issue: 4
Pages: 647-660
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27498076 | J:319201
First Author: Markandeya YS
Year: 2016
Journal: Heart Rhythm
Title: Inhibition of late sodium current attenuates ionic arrhythmia mechanism in ventricular myocytes expressing LaminA-N195K mutation.
Volume: 13
Issue: 11
Pages: 2228-2236
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16445279 | J:106830
First Author: Ostlund C
Year: 2006
Journal: Biochemistry
Title: Dependence of diffusional mobility of integral inner nuclear membrane proteins on A-type lamins.
Volume: 45
Issue: 5
Pages: 1374-82
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19013199 | J:147236
First Author: Houben F
Year: 2009
Journal: Biochim Biophys Acta
Title: Disturbed nuclear orientation and cellular migration in A-type lamin deficient cells.
Volume: 1793
Issue: 2
Pages: 312-24
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19629036 | J:152006
First Author: Gonzalez-Suarez I
Year: 2009
Journal: EMBO J
Title: Novel roles for A-type lamins in telomere biology and the DNA damage response pathway.
Volume: 28
Issue: 16
Pages: 2414-27
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21831885 | J:176678
First Author: De Vos WH
Year: 2011
Journal: Hum Mol Genet
Title: Repetitive disruptions of the nuclear envelope invoke temporary loss of cellular compartmentalization in laminopathies.
Volume: 20
Issue: 21
Pages: 4175-86
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23427149 | J:198152
First Author: Zwerger M
Year: 2013
Journal: Hum Mol Genet
Title: Myopathic lamin mutations impair nuclear stability in cells and tissue and disrupt nucleo-cytoskeletal coupling.
Volume: 22
Issue: 12
Pages: 2335-49
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33388782 | J:304460
First Author: Dridi H
Year: 2021
Journal: Hum Mol Genet
Title: Ryanodine receptor remodeling in cardiomyopathy and muscular dystrophy caused by lamin A/C gene mutation.
Volume: 29
Issue: 24
Pages: 3919-3934
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Publication
20439468 | J:165928
First Author: Coffinier C
Year: 2010
Journal: J Biol Chem
Title: Direct synthesis of lamin A, bypassing prelamin a processing, causes misshapen nuclei in fibroblasts but no detectable pathology in mice.
Volume: 285
Issue: 27
Pages: 20818-26
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23217256 | J:194166
First Author: Liu B
Year: 2012
Journal: Cell Metab
Title: Resveratrol rescues SIRT1-dependent adult stem cell decline and alleviates progeroid features in laminopathy-based progeria.
Volume: 16
Issue: 6
Pages: 738-50
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27131347 | J:236702
First Author: Chatzifrangkeskou M
Year: 2016
Journal: Hum Mol Genet
Title: ERK1/2 directly acts on CTGF/CCN2 expression to mediate myocardial fibrosis in cardiomyopathy caused by mutations in the lamin A/C gene.
Volume: 25
Issue: 11
Pages: 2220-2233
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34433058 | J:320608
First Author: Vignier N
Year: 2021
Journal: Cell Rep
Title: The non-muscle ADF/cofilin-1 controls sarcomeric actin filament integrity and force production in striated muscle laminopathies.
Volume: 36
Issue: 8
Pages: 109601
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15210943 | J:91426
First Author: Johnson BR
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: A-type lamins regulate retinoblastoma protein function by promoting subnuclear localization and preventing proteasomal degradation.
Volume: 101
Issue: 26
Pages: 9677-82
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Publication
23695662 | J:244335
 
First Author: Liu B
Year: 2013
Journal: Nat Commun
Title: Depleting the methyltransferase Suv39h1 improves DNA repair and extends lifespan in a progeria mouse model.
Volume: 4
Pages: 1868
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28069793 | J:241598
First Author: Le Dour C
Year: 2017
Journal: Hum Mol Genet
Title: Decreased WNT/β-catenin signalling contributes to the pathogenesis of dilated cardiomyopathy caused by mutations in the lamin a/C gene.
Volume: 26
Issue: 2
Pages: 333-343
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21156181 | J:171019
First Author: Nikolova-Krstevski V
Year: 2011
Journal: J Mol Cell Cardiol
Title: Nesprin-1 and actin contribute to nuclear and cytoskeletal defects in lamin A/C-deficient cardiomyopathy.
Volume: 50
Issue: 3
Pages: 479-86
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•
•
Publication
17567779 | J:125115
First Author: Muchir A
Year: 2007
Journal: Hum Mol Genet
Title: Activation of MAPK in hearts of EMD null mice: similarities between mouse models of X-linked and autosomal dominant Emery Dreifuss muscular dystrophy.
Volume: 16
Issue: 15
Pages: 1884-95
•
•
•
•
•
Publication
11799477 | J:75378
First Author: De Sandre-Giovannoli A
Year: 2002
Journal: Am J Hum Genet
Title: Homozygous defects in LMNA, encoding lamin A/C nuclear-envelope proteins, cause autosomal recessive axonal neuropathy in human (Charcot-Marie-Tooth disorder type 2) and mouse.
Volume: 70
Issue: 3
Pages: 726-36
•
•
•
•
•
Publication
15367494 | J:94403
First Author: Broers JL
Year: 2004
Journal: Hum Mol Genet
Title: Decreased mechanical stiffness in LMNA-/- cells is caused by defective nucleo-cytoskeletal integrity: implications for the development of laminopathies.
Volume: 13
Issue: 21
Pages: 2567-80
•
•
•
•
•
Publication
32805188 | J:304129
First Author: Coste Pradas J
Year: 2020
Journal: J Am Heart Assoc
Title: Identification of Genes and Pathways Regulated by Lamin A in Heart.
Volume: 9
Issue: 16
Pages: e015690
•
•
•
•
•
Publication
25578479 | J:220874
First Author: Wang AS
Year: 2015
Journal: Differentiation
Title: Tissue specific loss of A-type lamins in the gastrointestinal epithelium can enhance polyp size.
Volume: 89
Issue: 1-2
Pages: 11-21
•
•
•
•
•
Publication
33393499 | J:299979
 
First Author: Guénantin AC
Year: 2021
Journal: J Clin Invest
Title: Targeting the histone demethylase LSD1 prevents cardiomyopathy in a mouse model of laminopathy.
Volume: 131
Issue: 1
•
•
•
•
•
Publication
25343989 | J:219228
First Author: Baek JH
Year: 2015
Journal: Hum Mol Genet
Title: Expression of progerin in aging mouse brains reveals structural nuclear abnormalities without detectible significant alterations in gene expression, hippocampal stem cells or behavior.
Volume: 24
Issue: 5
Pages: 1305-21
•
•
•
•
•
Publication
36644279 | J:334042
First Author: Cheedipudi SM
Year: 2022
Journal: JACC Basic Transl Sci
Title: Genetic Ablation of the DNA Damage Response Pathway Attenuates Lamin-Associated Dilated Cardiomyopathy in Mice.
Volume: 7
Issue: 12
Pages: 1232-1245
•
•
•
•
•
Publication
32484798 | J:302487
First Author: Auguste G
Year: 2020
Journal: J Clin Invest
Title: BET bromodomain inhibition attenuates cardiac phenotype in myocyte-specific lamin A/C-deficient mice.
Volume: 130
Issue: 9
Pages: 4740-4758
•
•
•
•
•
Publication
33049978 | J:313497
 
First Author: Nevado RM
Year: 2020
Journal: Cells
Title: Premature Vascular Aging with Features of Plaque Vulnerability in an Atheroprone Mouse Model of Hutchinson-Gilford Progeria Syndrome with Ldlr Deficiency.
Volume: 9
Issue: 10
•
•
•
•
•
Publication
34453483 | J:310345
First Author: Cabral WA
Year: 2021
Journal: Aging Cell
Title: Genetic reduction of mTOR extends lifespan in a mouse model of Hutchinson-Gilford Progeria syndrome.
Volume: 20
Issue: 9
Pages: e13457
•
•
•
•
•
Publication
29668927 | J:263781
First Author: Choi JC
Year: 2018
Journal: Hum Mol Genet
Title: Elevated dual specificity protein phosphatase 4 in cardiomyopathy caused by lamin A/C gene mutation is primarily ERK1/2-dependent and its depletion improves cardiac function and survival.
Volume: 27
Issue: 13
Pages: 2290-2305
•
•
•
•
•
Publication
21464947 | J:171665
First Author: Pratt CH
Year: 2011
Journal: PLoS One
Title: Mitotic defects lead to pervasive aneuploidy and accompany loss of RB1 activity in mouse LmnaDhe dermal fibroblasts.
Volume: 6
Issue: 3
Pages: e18065
•
•
•
•
•
Publication
22773734 | J:187399
First Author: Muchir A
Year: 2012
Journal: Hum Mol Genet
Title: Abnormal p38α mitogen-activated protein kinase signaling in dilated cardiomyopathy caused by lamin A/C gene mutation.
Volume: 21
Issue: 19
Pages: 4325-33
•
•
•
•
•
Publication
23631840 | J:218662
First Author: Arimura T
Year: 2013
Journal: Cardiovasc Res
Title: Nuclear accumulation of androgen receptor in gender difference of dilated cardiomyopathy due to lamin A/C mutations.
Volume: 99
Issue: 3
Pages: 382-94
•
•
•
•
•
Publication
23261543 | J:194403
First Author: Chen SC
Year: 2013
Journal: Exp Cell Res
Title: Phosphorylation of connexin43 on S279/282 may contribute to laminopathy-associated conduction defects.
Volume: 319
Issue: 6
Pages: 888-96
•
•
•
•
•
Publication
31430335 | J:278718
First Author: Wada E
Year: 2019
Journal: PLoS One
Title: Deficiency of emerin contributes differently to the pathogenesis of skeletal and cardiac muscles in LmnaH222P/H222P mutant mice.
Volume: 14
Issue: 8
Pages: e0221512
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•
•
•
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