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Search results 401 to 500 out of 717 for Lmna

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Type Details Score
GXD Expression
GXD Expression
     
Probe: MGI:6471036
Assay Type: Immunohistochemistry
Annotation Date: 2020-11-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287328
Stage: TS28
Assay Id: MGI:6471057
Age: postnatal day 5
Specimen Label: not shown
Detected: false
Specimen Num: 23
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GXD Expression
GXD Expression
     
Probe: MGI:6471036
Assay Type: Immunohistochemistry
Annotation Date: 2020-11-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287327
Stage: TS27
Assay Id: MGI:6471057
Age: postnatal day 1
Specimen Label: not shown
Detected: false
Specimen Num: 22
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GXD Expression
GXD Expression
     
Probe: MGI:6471036
Assay Type: Immunohistochemistry
Annotation Date: 2020-11-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287328
Stage: TS28
Assay Id: MGI:6471057
Age: postnatal day 10
Specimen Label: not shown
Detected: false
Specimen Num: 24
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GXD Expression
GXD Expression
     
Probe: MGI:6471036
Assay Type: Immunohistochemistry
Annotation Date: 2020-11-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287328
Stage: TS28
Assay Id: MGI:6471057
Age: postnatal day 15
Specimen Label: not shown
Detected: false
Specimen Num: 25
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GXD Expression
GXD Expression
   
Probe: MGI:6471036
Assay Type: Immunohistochemistry
Annotation Date: 2020-11-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:6471085
Age: postnatal day 1
Image: 4A
Specimen Label: 4A
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6471036
Assay Type: Immunohistochemistry
Annotation Date: 2020-11-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:6471057
Age: postnatal day 1
Image: 4B
Specimen Label: 4B
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:6471036
Assay Type: Immunohistochemistry
Annotation Date: 2020-11-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6471057
Age: postnatal adult
Image: 4J
Note: Expressed in the nuclei.
Specimen Label: 4J
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:6471036
Assay Type: Immunohistochemistry
Annotation Date: 2020-11-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6471057
Age: postnatal day 5
Note: Expressed in a minority of cells.
Specimen Label: not shown
Detected: true
Specimen Num: 23
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GXD Expression
GXD Expression
 
Probe: MGI:6471036
Assay Type: Immunohistochemistry
Annotation Date: 2020-11-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6471057
Age: postnatal day 10
Note: Expressed in a minority of cells.
Specimen Label: not shown
Detected: true
Specimen Num: 24
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GXD Expression
GXD Expression
   
Probe: MGI:6471036
Assay Type: Immunohistochemistry
Annotation Date: 2020-11-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6471057
Age: postnatal day 15
Specimen Label: not shown
Detected: true
Specimen Num: 25
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GXD Expression
GXD Expression
 
Probe: MGI:4420614
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1761823
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825946
Age: embryonic day 14.5
Image: euxassay_000214_11
Specimen Label: euxassay_000214_11
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:4420614
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1761823
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825946
Age: embryonic day 14.5
Image: euxassay_000214_12
Specimen Label: euxassay_000214_12
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:4420614
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1761823
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825946
Age: embryonic day 14.5
Image: euxassay_000214_13
Specimen Label: euxassay_000214_13
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
 
Probe: MGI:4420614
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1761823
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825946
Age: embryonic day 14.5
Image: euxassay_000214_14
Specimen Label: euxassay_000214_14
Detected: true
Specimen Num: 14
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Genotype
Genotype
Symbol: Lmna/Lmna
Background: involves: 129 * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0110640 | congenital muscular dystrophy due to LMNA mutation
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Publication
2719959 | J:16565
First Author: Riedel W
Year: 1989
Journal: Biochim Biophys Acta
Title: Nucleotide sequence of the full-length mouse lamin C cDNA and its deduced amino-acid sequence.
Volume: 1008
Issue: 1
Pages: 119-22
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Publication
23535822 | J:198543
First Author: Cohen TV
Year: 2013
Journal: Hum Mol Genet
Title: Defective skeletal muscle growth in lamin A/C-deficient mice is rescued by loss of Lap2α.
Volume: 22
Issue: 14
Pages: 2852-69
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Publication
33907225 | J:313779
First Author: Kang SM
Year: 2021
Journal: Sci Rep
Title: Human WRN is an intrinsic inhibitor of progerin, abnormal splicing product of lamin A.
Volume: 11
Issue: 1
Pages: 9122
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Publication
23444379 | J:200658
First Author: Pilat U
Year: 2013
Journal: J Cell Sci
Title: The muscle dystrophy-causing ΔK32 lamin A/C mutant does not impair the functions of the nucleoplasmic lamin-A/C-LAP2α complex in mice.
Volume: 126
Issue: Pt 8
Pages: 1753-62
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Publication
18849980 | J:145628
First Author: Naetar N
Year: 2008
Journal: Nat Cell Biol
Title: Loss of nucleoplasmic LAP2alpha-lamin A complexes causes erythroid and epidermal progenitor hyperproliferation.
Volume: 10
Issue: 11
Pages: 1341-8
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Publication
35413292 | J:325669
     
First Author: Li G
Year: 2022
Journal: J Invest Dermatol
Title: Aging-Conferred SIRT7 Decline Inhibits Rosacea-Like Skin Inflammation by Modulating Toll-Like Receptor 2‒NF-κB Signaling.
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Publication
16481476 | J:105720
First Author: Frock RL
Year: 2006
Journal: Genes Dev
Title: Lamin A/C and emerin are critical for skeletal muscle satellite cell differentiation.
Volume: 20
Issue: 4
Pages: 486-500
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Publication
25609380 | J:219709
 
First Author: Furusawa T
Year: 2015
Journal: Nat Commun
Title: Chromatin decompaction by the nucleosomal binding protein HMGN5 impairs nuclear sturdiness.
Volume: 6
Pages: 6138
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Publication
28088180 | J:313343
First Author: Smith ER
Year: 2017
Journal: BMC Cell Biol
Title: Nuclear envelope structural proteins facilitate nuclear shape changes accompanying embryonic differentiation and fidelity of gene expression.
Volume: 18
Issue: 1
Pages: 8
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Publication
32807790 | J:303342
First Author: Pitrez PR
Year: 2020
Journal: Nat Commun
Title: Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13.
Volume: 11
Issue: 1
Pages: 4110
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Publication
12670476 | J:83147
First Author: Lattanzi G
Year: 2003
Journal: Biochem Biophys Res Commun
Title: Association of emerin with nuclear and cytoplasmic actin is regulated in differentiating myoblasts.
Volume: 303
Issue: 3
Pages: 764-70
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Publication
15356259 | J:95341
First Author: Vecerová J
Year: 2004
Journal: Mol Biol Cell
Title: Formation of nuclear splicing factor compartments is independent of lamins A/C.
Volume: 15
Issue: 11
Pages: 4904-10
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Publication
17321498 | J:120334
First Author: Mariappan I
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Identification of cyclin D3 as a new interaction partner of lamin A/C.
Volume: 355
Issue: 4
Pages: 981-5
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Publication
18836436 | J:145633
First Author: Han X
Year: 2008
Journal: Nat Cell Biol
Title: Tethering by lamin A stabilizes and targets the ING1 tumour suppressor.
Volume: 10
Issue: 11
Pages: 1333-40
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Publication
20726853 | J:217053
First Author: Oh YS
Year: 2010
Journal: Aging Cell
Title: Downregulation of lamin A by tumor suppressor AIMP3/p18 leads to a progeroid phenotype in mice.
Volume: 9
Issue: 5
Pages: 810-22
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Publication
25535984 | J:225663
First Author: González-Granado JM
Year: 2014
Journal: PLoS One
Title: Sorting nexin 6 enhances lamin a synthesis and incorporation into the nuclear envelope.
Volume: 9
Issue: 12
Pages: e115571
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Publication
28854361 | J:254935
First Author: Morelli FF
Year: 2017
Journal: Cell Rep
Title: Aberrant Compartment Formation by HSPB2 Mislocalizes Lamin A and Compromises Nuclear Integrity and Function.
Volume: 20
Issue: 9
Pages: 2100-2115
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Publication
16339967 | J:105608
First Author: Brachner A
Year: 2005
Journal: J Cell Sci
Title: LEM2 is a novel MAN1-related inner nuclear membrane protein associated with A-type lamins.
Volume: 118
Issue: Pt 24
Pages: 5797-810
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Publication
19915186 | J:155582
First Author: Yamada M
Year: 2010
Journal: Hum Mol Genet
Title: Involvement of a novel preimplantation-specific gene encoding the high mobility group box protein Hmgpi in early embryonic development.
Volume: 19
Issue: 3
Pages: 480-93
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Publication
38322613 | J:345880
 
First Author: Ferrand MC
Year: 2024
Journal: Front Physiol
Title: Intracardiac electrophysiology to characterize susceptibility to ventricular arrhythmias in murine models.
Volume: 15
Pages: 1326663
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Publication
25312645 | J:224318
First Author: Jung HJ
Year: 2014
Journal: Mol Cell Biol
Title: An absence of nuclear lamins in keratinocytes leads to ichthyosis, defective epidermal barrier function, and intrusion of nuclear membranes and endoplasmic reticulum into the nuclear chromatin.
Volume: 34
Issue: 24
Pages: 4534-44
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Publication
30283351 | J:301115
 
First Author: Braumann S
Year: 2018
Journal: Front Physiol
Title: S100A4 as a Target of the E3-Ligase Asb2β and Its Effect on Engineered Heart Tissue.
Volume: 9
Pages: 1292
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Publication
33526168 | J:301407
   
First Author: Chen X
Year: 2021
Journal: Elife
Title: A small-molecule ICMT inhibitor delays senescence of Hutchinson-Gilford progeria syndrome cells.
Volume: 10
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Publication
31397869 | J:298234
First Author: Šoltić D
Year: 2019
Journal: Hum Mol Genet
Title: Lamin A/C dysregulation contributes to cardiac pathology in a mouse model of severe spinal muscular atrophy.
Volume: 28
Issue: 21
Pages: 3515-3527
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Publication
32817327 | J:298277
First Author: Gao N
Year: 2020
Journal: J Neurosci
Title: A Role of Lamin A/C in Preventing Neuromuscular Junction Decline in Mice.
Volume: 40
Issue: 38
Pages: 7203-7215
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Publication
27984723 | J:238056
First Author: Ocampo A
Year: 2016
Journal: Cell
Title: In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming.
Volume: 167
Issue: 7
Pages: 1719-1733.e12
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Publication
32479501 | J:293271
First Author: Xiong L
Year: 2020
Journal: PLoS Biol
Title: Linking skeletal muscle aging with osteoporosis by lamin A/C deficiency.
Volume: 18
Issue: 6
Pages: e3000731
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Publication
17488709 | J:123495
First Author: Ji JY
Year: 2007
Journal: J Biol Chem
Title: Cell nuclei spin in the absence of lamin b1.
Volume: 282
Issue: 27
Pages: 20015-26
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Publication
15980864 | J:99634
First Author: Liu B
Year: 2005
Journal: Nat Med
Title: Genomic instability in laminopathy-based premature aging.
Volume: 11
Issue: 7
Pages: 780-5
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Publication
31332389 | J:298792
First Author: Bárcena C
Year: 2019
Journal: Nat Med
Title: Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice.
Volume: 25
Issue: 8
Pages: 1234-1242
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Publication
30157432 | J:270748
First Author: Bárcena C
Year: 2018
Journal: Cell Rep
Title: Methionine Restriction Extends Lifespan in Progeroid Mice and Alters Lipid and Bile Acid Metabolism.
Volume: 24
Issue: 9
Pages: 2392-2403
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Publication
33972393 | J:310088
First Author: Smith ER
Year: 2021
Journal: Mol Cell Biol
Title: Nuclear Lamin A/C Expression Is a Key Determinant of Paclitaxel Sensitivity.
Volume: 41
Issue: 7
Pages: e0064820
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Publication
25237101 | J:213767
First Author: Arimura S
Year: 2014
Journal: Science
Title: Neuromuscular disease. DOK7 gene therapy benefits mouse models of diseases characterized by defects in the neuromuscular junction.
Volume: 345
Issue: 6203
Pages: 1505-8
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Publication
20833363 | J:164281
First Author: Hernandez L
Year: 2010
Journal: Dev Cell
Title: Functional coupling between the extracellular matrix and nuclear lamina by Wnt signaling in progeria.
Volume: 19
Issue: 3
Pages: 413-25
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Publication
30575733 | J:270376
First Author: Ovadya Y
Year: 2018
Journal: Nat Commun
Title: Impaired immune surveillance accelerates accumulation of senescent cells and aging.
Volume: 9
Issue: 1
Pages: 5435
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Publication
23029315 | J:191971
First Author: Boudreau É
Year: 2012
Journal: PLoS One
Title: Lamin A/C mutants disturb sumo1 localization and sumoylation in vitro and in vivo.
Volume: 7
Issue: 9
Pages: e45918
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Publication
28241138 | J:343395
First Author: Turgay Y
Year: 2017
Journal: Nature
Title: The molecular architecture of lamins in somatic cells.
Volume: 543
Issue: 7644
Pages: 261-264
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Publication
11739632 | J:73171
First Author: Muralikrishna B
Year: 2001
Journal: J Cell Sci
Title: Distinct changes in intranuclear lamin A/C organization during myoblast differentiation.
Volume: 114
Issue: Pt 22
Pages: 4001-11
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Publication
18664494 | J:139951
First Author: Ojeh N
Year: 2008
Journal: J Cell Sci
Title: The MAGUK-family protein CASK is targeted to nuclei of the basal epidermis and controls keratinocyte proliferation.
Volume: 121
Issue: Pt 16
Pages: 2705-17
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Publication
7680212 | J:3817
First Author: Moss SB
Year: 1993
Journal: Mol Reprod Dev
Title: The differential expression of lamin epitopes during mouse spermatogenesis.
Volume: 34
Issue: 2
Pages: 164-74
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Publication
30906869 | J:288441
First Author: Ao Y
Year: 2019
Journal: Sci Adv
Title: Lamin A buffers CK2 kinase activity to modulate aging in a progeria mouse model.
Volume: 5
Issue: 3
Pages: eaav5078
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Publication
3046911 | J:289360
First Author: Houliston E
Year: 1988
Journal: Development
Title: Expression of nuclear lamins during mouse preimplantation development.
Volume: 102
Issue: 2
Pages: 271-8
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Publication
16380439 | J:104409
First Author: Crisp M
Year: 2006
Journal: J Cell Biol
Title: Coupling of the nucleus and cytoplasm: role of the LINC complex.
Volume: 172
Issue: 1
Pages: 41-53
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Publication
16648470 | J:109072
First Author: Haque F
Year: 2006
Journal: Mol Cell Biol
Title: SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton.
Volume: 26
Issue: 10
Pages: 3738-51
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Publication
19933576 | J:159127
First Author: Haque F
Year: 2010
Journal: J Biol Chem
Title: Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes.
Volume: 285
Issue: 5
Pages: 3487-98
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Publication
8032679 | J:19855
First Author: Furukawa K
Year: 1994
Journal: Chromosome Res
Title: cDNA cloning and functional characterization of a meiosis-specific protein (MNS1) with apparent nuclear association.
Volume: 2
Issue: 2
Pages: 99-113
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Publication
23071752 | J:192230
First Author: Razafsky D
Year: 2012
Journal: PLoS One
Title: LINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retina.
Volume: 7
Issue: 10
Pages: e47180
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Publication
30968547 | J:277664
First Author: Yue S
Year: 2019
Journal: Aging Cell
Title: Cell-type-specific role of lamin-B1 in thymus development and its inflammation-driven reduction in thymus aging.
Volume: 18
Issue: 4
Pages: e12952
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Publication
23019125 | J:188267
First Author: Osorio FG
Year: 2012
Journal: Genes Dev
Title: Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response.
Volume: 26
Issue: 20
Pages: 2311-24
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Publication
23374351 | J:193454
First Author: Solovei I
Year: 2013
Journal: Cell
Title: LBR and lamin A/C sequentially tether peripheral heterochromatin and inversely regulate differentiation.
Volume: 152
Issue: 3
Pages: 584-98
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Publication
25437426 | J:220043
First Author: Hosseini M
Year: 2015
Journal: J Invest Dermatol
Title: Premature skin aging features rescued by inhibition of NADPH oxidase activity in XPC-deficient mice.
Volume: 135
Issue: 4
Pages: 1108-1118
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Publication
32175648 | J:303083
First Author: Shimizu A
Year: 2020
Journal: FASEB J
Title: Identification of transmembrane protein 168 mutation in familial Brugada syndrome.
Volume: 34
Issue: 5
Pages: 6399-6417
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Publication
23686339 | J:199185
First Author: Ibrahim MX
Year: 2013
Journal: Science
Title: Targeting isoprenylcysteine methylation ameliorates disease in a mouse model of progeria.
Volume: 340
Issue: 6138
Pages: 1330-3
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Publication
12235369 | J:79501
First Author: Bergo MO
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Zmpste24 deficiency in mice causes spontaneous bone fractures, muscle weakness, and a prelamin A processing defect.
Volume: 99
Issue: 20
Pages: 13049-54
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Publication
30282816 | J:294507
 
First Author: Levy Y
Year: 2018
Journal: JCI Insight
Title: Prelamin A causes aberrant myonuclear arrangement and results in muscle fiber weakness.
Volume: 3
Issue: 19
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Publication
35309931 | J:329157
 
First Author: Hishida T
Year: 2022
Journal: Front Cell Dev Biol
Title: Myc Supports Self-Renewal of Basal Cells in the Esophageal Epithelium.
Volume: 10
Pages: 786031
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Publication
27926859 | J:241675
First Author: Liao CY
Year: 2016
Journal: Cell Rep
Title: Rapamycin Reverses Metabolic Deficits in Lamin A/C-Deficient Mice.
Volume: 17
Issue: 10
Pages: 2542-2552
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Publication
21750527 | J:176746
First Author: Gonzalez-Suarez I
Year: 2011
Journal: EMBO J
Title: A new pathway that regulates 53BP1 stability implicates cathepsin L and vitamin D in DNA repair.
Volume: 30
Issue: 16
Pages: 3383-96
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Publication
25380821 | J:218218
First Author: Viera A
Year: 2015
Journal: J Cell Sci
Title: CDK2 regulates nuclear envelope protein dynamics and telomere attachment in mouse meiotic prophase.
Volume: 128
Issue: 1
Pages: 88-99
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Publication
16731532 | J:116472
First Author: Dai FF
Year: 2006
Journal: J Biol Chem
Title: The neuronal Ca2+ sensor protein visinin-like protein-1 is expressed in pancreatic islets and regulates insulin secretion.
Volume: 281
Issue: 31
Pages: 21942-53
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Publication
15219855 | J:90951
First Author: Okumura K
Year: 2004
Journal: Biochem Biophys Res Commun
Title: c-Jun and Sp1 family are critical for retinoic acid induction of the lamin A/C retinoic acid-responsive element.
Volume: 320
Issue: 2
Pages: 487-92
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Publication
19022376 | J:143904
First Author: Muchir A
Year: 2009
Journal: Biochim Biophys Acta
Title: Reduced expression of A-type lamins and emerin activates extracellular signal-regulated kinase in cultured cells.
Volume: 1792
Issue: 1
Pages: 75-81
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Publication
26045045 | J:260379
First Author: Naeem AS
Year: 2015
Journal: Cell Death Differ
Title: AKT1-mediated Lamin A/C degradation is required for nuclear degradation and normal epidermal terminal differentiation.
Volume: 22
Issue: 12
Pages: 2123-32
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Publication
2680424 | J:289359
First Author: Röber RA
Year: 1989
Journal: Development
Title: Differential timing of nuclear lamin A/C expression in the various organs of the mouse embryo and the young animal: a developmental study.
Volume: 105
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