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Search results 1 to 100 out of 235 for Ern1

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Category: Publication
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Type Details Score
Publication
11146108 | J:66969
First Author: Miyoshi K
Year: 2000
Journal: Brain Res Mol Brain Res
Title: Characterization of mouse Ire1 alpha: cloning, mRNA localization in the brain and functional analysis in a neural cell line.
Volume: 85
Issue: 1-2
Pages: 68-76
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Publication
25164867 | J:255334
 
First Author: Sanches M
Year: 2014
Journal: Nat Commun
Title: Structure and mechanism of action of the hydroxy-aryl-aldehyde class of IRE1 endoribonuclease inhibitors.
Volume: 5
Pages: 4202
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Publication
28825721 | J:251029
First Author: Li XX
Year: 2017
Journal: Oncogene
Title: Knockdown of IRE1α inhibits colonic tumorigenesis through decreasing β-catenin and IRE1α targeting suppresses colon cancer cells.
Volume: 36
Issue: 48
Pages: 6738-6746
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Publication
33610548 | J:304808
   
First Author: Foley KP
Year: 2021
Journal: J Biol Chem
Title: Inflammation promotes adipocyte lipolysis via IRE1 kinase.
Pages: 100440
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Publication
25925952 | J:271354
First Author: Zhang HS
Year: 2015
Journal: J Biol Chem
Title: The Endoplasmic Reticulum Stress Sensor IRE1α in Intestinal Epithelial Cells Is Essential for Protecting against Colitis.
Volume: 290
Issue: 24
Pages: 15327-36
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Publication
35500653 | J:325540
First Author: Li Y
Year: 2022
Journal: J Biol Chem
Title: Phosphorylation at Ser724 of the ER stress sensor IRE1α governs its activation state and limits ER stress-induced hepatosteatosis.
Volume: 298
Issue: 6
Pages: 101997
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Publication
30687308 | J:294745
 
First Author: Medel B
Year: 2018
Journal: Front Immunol
Title: IRE1α Activation in Bone Marrow-Derived Dendritic Cells Modulates Innate Recognition of Melanoma Cells and Favors CD8+ T Cell Priming.
Volume: 9
Pages: 3050
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Publication
21407177 | J:171230
First Author: Zhang K
Year: 2011
Journal: EMBO J
Title: The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis.
Volume: 30
Issue: 7
Pages: 1357-75
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Publication
29764990 | J:284455
 
First Author: Wang JM
Year: 2018
Journal: Sci Signal
Title: IRE1α prevents hepatic steatosis by processing and promoting the degradation of select microRNAs.
Volume: 11
Issue: 530
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Publication
31110288 | J:282926
First Author: Carreras-Sureda A
Year: 2019
Journal: Nat Cell Biol
Title: Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics.
Volume: 21
Issue: 6
Pages: 755-767
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Publication
26469762 | J:226385
First Author: Hassler JR
Year: 2015
Journal: PLoS Biol
Title: The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of β Cells.
Volume: 13
Issue: 10
Pages: e1002277
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Publication
15690081 | J:106975
First Author: Zhang K
Year: 2005
Journal: J Clin Invest
Title: The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis.
Volume: 115
Issue: 2
Pages: 268-81
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Publication
21896783 | J:178323
First Author: Meares GP
Year: 2011
Journal: Mol Cell Biol
Title: IRE1-dependent activation of AMPK in response to nitric oxide.
Volume: 31
Issue: 21
Pages: 4286-97
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Publication
32409639 | J:293066
First Author: Dufey E
Year: 2020
Journal: Nat Commun
Title: Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response.
Volume: 11
Issue: 1
Pages: 2401
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Publication
34145058 | J:320469
First Author: Abuaita BH
Year: 2021
Journal: J Immunol
Title: The IRE1α Stress Signaling Axis Is a Key Regulator of Neutrophil Antimicrobial Effector Function.
Volume: 207
Issue: 1
Pages: 210-220
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Publication
34808241 | J:324913
First Author: Son J
Year: 2022
Journal: J Invest Dermatol
Title: The Endoplasmic Reticulum Stress Sensor IRE1α Regulates the UV DNA Repair Response through the Control of Intracellular Calcium Homeostasis.
Volume: 142
Issue: 6
Pages: 1682-1691.e7
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Publication
12446770 | J:80611
First Author: Marcu MG
Year: 2002
Journal: Mol Cell Biol
Title: Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha.
Volume: 22
Issue: 24
Pages: 8506-13
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Publication
17030611 | J:117626
First Author: Ogata M
Year: 2006
Journal: Mol Cell Biol
Title: Autophagy is activated for cell survival after endoplasmic reticulum stress.
Volume: 26
Issue: 24
Pages: 9220-31
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Publication
17035634 | J:117946
First Author: Goffin L
Year: 2006
Journal: Mol Biol Cell
Title: The unfolded protein response transducer Ire1p contains a nuclear localization sequence recognized by multiple beta importins.
Volume: 17
Issue: 12
Pages: 5309-23
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Publication
17991856 | J:127332
First Author: Lin JH
Year: 2007
Journal: Science
Title: IRE1 signaling affects cell fate during the unfolded protein response.
Volume: 318
Issue: 5852
Pages: 944-9
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Publication
18035051 | J:130201
First Author: Han D
Year: 2008
Journal: Biochem Biophys Res Commun
Title: A kinase inhibitor activates the IRE1alpha RNase to confer cytoprotection against ER stress.
Volume: 365
Issue: 4
Pages: 777-83
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Publication
20702765 | J:163679
First Author: Auf G
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Inositol-requiring enzyme 1alpha is a key regulator of angiogenesis and invasion in malignant glioma.
Volume: 107
Issue: 35
Pages: 15553-8
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Publication
20798350 | J:164375
First Author: Li H
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering.
Volume: 107
Issue: 37
Pages: 16113-8
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Publication
23803178 | J:214026
First Author: Kitai Y
Year: 2013
Journal: Genes Cells
Title: Membrane lipid saturation activates IRE1α without inducing clustering.
Volume: 18
Issue: 9
Pages: 798-809
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Publication
24915138 | J:219443
First Author: Pierre N
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Activation of ER stress by hydrogen peroxide in C2C12 myotubes.
Volume: 450
Issue: 1
Pages: 459-63
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Publication
28346409 | J:259446
First Author: Shan B
Year: 2017
Journal: Nat Immunol
Title: The metabolic ER stress sensor IRE1α suppresses alternative activation of macrophages and impairs energy expenditure in obesity.
Volume: 18
Issue: 5
Pages: 519-529
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Publication
27743894 | J:260895
First Author: Homma T
Year: 2016
Journal: Exp Cell Res
Title: Heat stress promotes the down-regulation of IRE1α in cells: An atypical modulation of the UPR pathway.
Volume: 349
Issue: 1
Pages: 128-138
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Publication
31921161 | J:298431
 
First Author: Studencka-Turski M
Year: 2019
Journal: Front Immunol
Title: Molecular Insight Into the IRE1α-Mediated Type I Interferon Response Induced by Proteasome Impairment in Myeloid Cells of the Brain.
Volume: 10
Pages: 2900
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Publication
33561013 | J:339590
 
First Author: Sule G
Year: 2021
Journal: J Clin Invest
Title: Endoplasmic reticulum stress sensor IRE1α propels neutrophil hyperactivity in lupus.
Volume: 131
Issue: 7
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Publication
36179879 | J:329934
 
First Author: Chalmers FE
Year: 2022
Journal: Dev Biol
Title: The unfolded protein response gene Ire1α is required for tissue renewal and normal differentiation in the mouse tongue and esophagus.
Volume: 492
Pages: 59-70
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Publication
28128204 | J:244198
 
First Author: Liu J
Year: 2017
Journal: Nat Commun
Title: A critical role of DDRGK1 in endoplasmic reticulum homoeostasis via regulation of IRE1α stability.
Volume: 8
Pages: 14186
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Publication
11850408 | J:107824
First Author: Lee K
Year: 2002
Journal: Genes Dev
Title: IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response.
Volume: 16
Issue: 4
Pages: 452-66
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Publication
19135427 | J:145150
First Author: Nagai A
Year: 2009
Journal: Biochem Biophys Res Commun
Title: USP14 inhibits ER-associated degradation via interaction with IRE1alpha.
Volume: 379
Issue: 4
Pages: 995-1000
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Publication
31368599 | J:282242
First Author: Takeda K
Year: 2019
Journal: EMBO J
Title: MITOL prevents ER stress-induced apoptosis by IRE1α ubiquitylation at ER-mitochondria contact sites.
Volume: 38
Issue: 15
Pages: e100999
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Publication
27797960 | J:252102
First Author: Oubaha M
Year: 2016
Journal: Sci Transl Med
Title: Senescence-associated secretory phenotype contributes to pathological angiogenesis in retinopathy.
Volume: 8
Issue: 362
Pages: 362ra144
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33728997 | J:308769
First Author: Xue F
Year: 2021
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Coordinated signaling of activating transcription factor 6α and inositol-requiring enzyme 1α regulates hepatic stellate cell-mediated fibrogenesis in mice.
Volume: 320
Issue: 5
Pages: G864-G879
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Publication
16581782 | J:107415
First Author: Hu P
Year: 2006
Journal: Mol Cell Biol
Title: Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression.
Volume: 26
Issue: 8
Pages: 3071-84
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Publication
30559399 | J:268418
First Author: Govindarajan S
Year: 2018
Journal: Nat Commun
Title: Stabilization of cytokine mRNAs in iNKT cells requires the serine-threonine kinase IRE1alpha.
Volume: 9
Issue: 1
Pages: 5340
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Publication
32243868 | J:293422
 
First Author: Van Campenhout S
Year: 2020
Journal: Metabolism
Title: Myeloid-specific IRE1alpha deletion reduces tumour development in a diabetic, non-alcoholic steatohepatitis-induced hepatocellular carcinoma mouse model.
Volume: 107
Pages: 154220
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Publication
29977610 | J:303409
 
First Author: Givord C
Year: 2018
Journal: NPJ Vaccines
Title: Activation of the endoplasmic reticulum stress sensor IRE1α by the vaccine adjuvant AS03 contributes to its immunostimulatory properties.
Volume: 3
Pages: 20
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Publication
37949065 | J:343574
First Author: Lee H
Year: 2023
Journal: Cell Metab
Title: Stress-induced β cell early senescence confers protection against type 1 diabetes.
Volume: 35
Issue: 12
Pages: 2200-2215.e9
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Publication
26240153 | J:225793
First Author: Qi Y
Year: 2015
Journal: J Biol Chem
Title: Sphingosine Kinase 1 Protects Hepatocytes from Lipotoxicity via Down-regulation of IRE1α Protein Expression.
Volume: 290
Issue: 38
Pages: 23282-90
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12020828 | J:76829
First Author: Noh SJ
Year: 2002
Journal: Biochim Biophys Acta
Title: Characterization of two homologs of Ire1p, a kinase/endoribonuclease in yeast, in Arabidopsis thaliana.
Volume: 1575
Issue: 1-3
Pages: 130-4
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Publication
16950141 | J:129740
First Author: Lipson KL
Year: 2006
Journal: Cell Metab
Title: Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1.
Volume: 4
Issue: 3
Pages: 245-54
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Publication
28550308 | J:246821
First Author: Pinkaew D
Year: 2017
Journal: Nat Commun
Title: Fortilin binds IRE1α and prevents ER stress from signaling apoptotic cell death.
Volume: 8
Issue: 1
Pages: 18
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Publication
32520957 | J:293449
First Author: Batista A
Year: 2020
Journal: PLoS Biol
Title: IRE1α regulates macrophage polarization, PD-L1 expression, and tumor survival.
Volume: 18
Issue: 6
Pages: e3000687
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Publication
31123148 | J:276550
First Author: Liu L
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Coupling of COPII vesicle trafficking to nutrient availability by the IRE1α-XBP1s axis.
Volume: 116
Issue: 24
Pages: 11776-11785
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Publication
24100031 | J:205913
First Author: Kemp KL
Year: 2013
Journal: J Biol Chem
Title: The serine-threonine kinase inositol-requiring enzyme 1α (IRE1α) promotes IL-4 production in T helper cells.
Volume: 288
Issue: 46
Pages: 33272-82
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Publication
32813318 | J:305752
First Author: Kumar A
Year: 2020
Journal: FASEB J
Title: Toll-like receptor 2 (TLR2) engages endoplasmic reticulum stress sensor IRE1α to regulate retinal innate responses in Staphylococcus aureus endophthalmitis.
Volume: 34
Issue: 10
Pages: 13826-13838
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Publication
28028078 | J:246084
First Author: Yao T
Year: 2017
Journal: Diabetes
Title: Ire1α in Pomc Neurons Is Required for Thermogenesis and Glycemia.
Volume: 66
Issue: 3
Pages: 663-673
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Publication
27634225 | J:246478
First Author: Wang JM
Year: 2017
Journal: Diabetes
Title: Inositol-Requiring Enzyme 1 Facilitates Diabetic Wound Healing Through Modulating MicroRNAs.
Volume: 66
Issue: 1
Pages: 177-192
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Publication
23040069 | J:190922
First Author: Wang S
Year: 2012
Journal: Cell Metab
Title: IRE1α-XBP1s induces PDI expression to increase MTP activity for hepatic VLDL assembly and lipid homeostasis.
Volume: 16
Issue: 4
Pages: 473-86
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Publication
31051095 | J:293740
First Author: Wang Q
Year: 2019
Journal: FASEB J
Title: Two pools of IRE1α in cardiac and skeletal muscle cells.
Volume: 33
Issue: 8
Pages: 8892-8904
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18049481 | J:146385
First Author: Kudo T
Year: 2008
Journal: Cell Death Differ
Title: A molecular chaperone inducer protects neurons from ER stress.
Volume: 15
Issue: 2
Pages: 364-75
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21415858 | J:173965
First Author: Tohmonda T
Year: 2011
Journal: EMBO Rep
Title: The IRE1α-XBP1 pathway is essential for osteoblast differentiation through promoting transcription of Osterix.
Volume: 12
Issue: 5
Pages: 451-7
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22291093 | J:181870
First Author: Hur KY
Year: 2012
Journal: J Exp Med
Title: IRE1α activation protects mice against acetaminophen-induced hepatotoxicity.
Volume: 209
Issue: 2
Pages: 307-18
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32220307 | J:287744
First Author: Lee H
Year: 2020
Journal: Cell Metab
Title: Beta Cell Dedifferentiation Induced by IRE1α Deletion Prevents Type 1 Diabetes.
Volume: 31
Issue: 4
Pages: 822-836.e5
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Publication
24441789 | J:209368
First Author: Osorio F
Year: 2014
Journal: Nat Immunol
Title: The unfolded-protein-response sensor IRE-1α regulates the function of CD8α+ dendritic cells.
Volume: 15
Issue: 3
Pages: 248-57
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Publication
28588082 | J:259497
 
First Author: Fink SL
Year: 2017
Journal: Sci Signal
Title: IRE1α promotes viral infection by conferring resistance to apoptosis.
Volume: 10
Issue: 482
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35030194 | J:322140
First Author: Liu X
Year: 2022
Journal: PLoS One
Title: Mechanisms of liver injury in high fat sugar diet fed mice that lack hepatocyte X-box binding protein 1.
Volume: 17
Issue: 1
Pages: e0261789
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26228140 | J:226327
First Author: Yang L
Year: 2015
Journal: Science
Title: METABOLISM. S-Nitrosylation links obesity-associated inflammation to endoplasmic reticulum dysfunction.
Volume: 349
Issue: 6247
Pages: 500-6
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23532846 | J:338768
First Author: Josekutty J
Year: 2013
Journal: J Biol Chem
Title: Microsomal triglyceride transfer protein inhibition induces endoplasmic reticulum stress and increases gene transcription via Ire1α/cJun to enhance plasma ALT/AST.
Volume: 288
Issue: 20
Pages: 14372-14383
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20885949 | J:165106
First Author: Iwawaki T
Year: 2010
Journal: PLoS One
Title: IRE1α disruption causes histological abnormality of exocrine tissues, increase of blood glucose level, and decrease of serum immunoglobulin level.
Volume: 5
Issue: 9
Pages: e13052
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29451493 | J:316374
   
First Author: Chapple RH
Year: 2018
Journal: Elife
Title: ERα promotes murine hematopoietic regeneration through the Ire1α-mediated unfolded protein response.
Volume: 7
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Publication
33010578 | J:329662
 
First Author: Lee HY
Year: 2020
Journal: Redox Biol
Title: The correlation of IRE1α oxidation with Nox4 activation in aging-associated vascular dysfunction.
Volume: 37
Pages: 101727
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11430819 | J:70005
First Author: Harding HP
Year: 2001
Journal: Mol Cell
Title: Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival.
Volume: 7
Issue: 6
Pages: 1153-63
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17367944 | J:122051
First Author: Murakami T
Year: 2007
Journal: Neuroscience
Title: Endoplasmic reticulum stress response in dendrites of cultured primary neurons.
Volume: 146
Issue: 1
Pages: 1-8
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20661282 | J:163090
First Author: Yang L
Year: 2010
Journal: PLoS One
Title: A Phos-tag-based approach reveals the extent of physiological endoplasmic reticulum stress.
Volume: 5
Issue: 7
Pages: e11621
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23473031 | J:198136
First Author: Binet F
Year: 2013
Journal: Cell Metab
Title: Neuronal ER stress impedes myeloid-cell-induced vascular regeneration through IRE1α degradation of netrin-1.
Volume: 17
Issue: 3
Pages: 353-71
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24945730 | J:213560
First Author: Le Pape S
Year: 2014
Journal: FEBS Lett
Title: Polynomial algebra reveals diverging roles of the unfolded protein response in endothelial cells during ischemia-reperfusion injury.
Volume: 588
Issue: 17
Pages: 3062-7
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25986605 | J:223302
   
First Author: Mendez AS
Year: 2015
Journal: Elife
Title: Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic.
Volume: 4
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28380378 | J:251836
First Author: Morita S
Year: 2017
Journal: Cell Metab
Title: Targeting ABL-IRE1α Signaling Spares ER-Stressed Pancreatic β Cells to Reverse Autoimmune Diabetes.
Volume: 25
Issue: 4
Pages: 883-897.e8
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Publication
23816533 | J:316967
First Author: Han X
Year: 2013
Journal: Cell Signal
Title: IRE1α dissociates with BiP and inhibits ER stress-mediated apoptosis in cartilage development.
Volume: 25
Issue: 11
Pages: 2136-46
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Publication
37874641 | J:343503
 
First Author: Smolgovsky S
Year: 2023
Journal: J Clin Invest
Title: Impaired T cell IRE1α/XBP1 signaling directs inflammation in experimental heart failure with preserved ejection fraction.
Volume: 133
Issue: 24
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9755171 | J:57921
First Author: Wang XZ
Year: 1998
Journal: EMBO J
Title: Cloning of mammalian Ire1 reveals diversity in the ER stress responses.
Volume: 17
Issue: 19
Pages: 5708-17
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21926971 | J:180014
First Author: Castillo K
Year: 2011
Journal: EMBO J
Title: BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response.
Volume: 30
Issue: 21
Pages: 4465-78
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23184933 | J:215858
First Author: Margariti A
Year: 2013
Journal: J Biol Chem
Title: XBP1 mRNA splicing triggers an autophagic response in endothelial cells through BECLIN-1 transcriptional activation.
Volume: 288
Issue: 2
Pages: 859-72
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30013108 | J:269148
First Author: Urra H
Year: 2018
Journal: Nat Cell Biol
Title: IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A.
Volume: 20
Issue: 8
Pages: 942-953
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32930709 | J:302975
 
First Author: Hagelkruys A
Year: 2021
Journal: J Exp Med
Title: A crucial role for Jagunal homolog 1 in humoral immunity and antibody glycosylation in mice and humans.
Volume: 218
Issue: 1
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10650002 | J:132966
First Author: Urano F
Year: 2000
Journal: Science
Title: Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1.
Volume: 287
Issue: 5453
Pages: 664-6
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18286202 | J:132805
First Author: Lipson KL
Year: 2008
Journal: PLoS One
Title: The role of IRE1alpha in the degradation of insulin mRNA in pancreatic beta-cells.
Volume: 3
Issue: 2
Pages: e1648
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Publication
25170079 | J:288191
First Author: Jiang S
Year: 2014
Journal: J Biol Chem
Title: Fibroblast growth factor 21 is regulated by the IRE1α-XBP1 branch of the unfolded protein response and counteracts endoplasmic reticulum stress-induced hepatic steatosis.
Volume: 289
Issue: 43
Pages: 29751-65
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Publication
30885990 | J:276223
First Author: Li H
Year: 2019
Journal: Diabetes
Title: Ameliorating Methylglyoxal-Induced Progenitor Cell Dysfunction for Tissue Repair in Diabetes.
Volume: 68
Issue: 6
Pages: 1287-1302
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Publication
34659198 | J:312700
 
First Author: Choi HJ
Year: 2021
Journal: Front Immunol
Title: XBP-1s Promotes B Cell Pathogenicity in Chronic GVHD by Restraining the Activity of Regulated IRE-1α-Dependent Decay.
Volume: 12
Pages: 705484
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25366967 | J:219656
First Author: Yang H
Year: 2014
Journal: J Exp Med
Title: Hrd1-mediated BLIMP-1 ubiquitination promotes dendritic cell MHCII expression for CD4 T cell priming during inflammation.
Volume: 211
Issue: 12
Pages: 2467-79
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First Author: Tang CA
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Journal: J Cell Biol
Title: Phosphorylation of IRE1 at S729 regulates RIDD in B cells and antibody production after immunization.
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Title: HIF1α-dependent hypoxia response in myeloid cells requires IRE1α.
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Journal: Dev Cell
Title: ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress.
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Title: Interleukin-1 receptor-associated kinase-2 (IRAK2) is a critical mediator of endoplasmic reticulum (ER) stress signaling.
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Journal: Cell Rep
Title: Saturated Fatty Acids Engage an IRE1α-Dependent Pathway to Activate the NLRP3 Inflammasome in Myeloid Cells.
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Title: Growth differentiation factor 15 ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice.
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Journal: Front Immunol
Title: Nuanced role for dendritic cell intrinsic IRE1 RNase in the regulation of antitumor adaptive immunity.
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Journal: Elife
Title: The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism.
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Title: Positive contribution of IRE1α-XBP1 pathway to the expression of placental cathepsins.
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Title: Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion.
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Title: The IRE1alpha-XBP1 pathway of the unfolded protein response is required for adipogenesis.
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Journal: Cell Metab
Title: IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress.
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Title: Multiple Mechanisms of Unfolded Protein Response-Induced Cell Death.
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Title: A crucial role for RACK1 in the regulation of glucose-stimulated IRE1alpha activation in pancreatic beta cells.
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