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Search results 1601 to 1652 out of 1652 for Prnp

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Type

Details

Score

Publication

31433986 | J:280229

First Author:	Wu T
Year:	2019
Journal:	Cell Rep
Title:	Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy.
Volume:	28
Issue:	8
Pages:	2111-2123.e6

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Publication

24945656 | J:245777

First Author:	Lacroux C
Year:	2014
Journal:	PLoS Pathog
Title:	Preclinical detection of variant CJD and BSE prions in blood.
Volume:	10
Issue:	6
Pages:	e1004202

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Publication

34644146 | J:324411

First Author:	Xiang X
Year:	2021
Journal:	Sci Transl Med
Title:	Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases.
Volume:	13
Issue:	615
Pages:	eabe5640

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Publication

19557827 | J:154721

First Author:	Pereson S
Year:	2009
Journal:	J Pathol
Title:	Progranulin expression correlates with dense-core amyloid plaque burden in Alzheimer disease mouse models.
Volume:	219
Issue:	2
Pages:	173-81

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Publication

11476963 | J:120781

First Author:	Lewis PA
Year:	2001
Journal:	Biochim Biophys Acta
Title:	Expression of BRI-amyloid beta peptide fusion proteins: a novel method for specific high-level expression of amyloid beta peptides.
Volume:	1537
Issue:	1
Pages:	58-62

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Strain

MGI:5013953 | STOCK Prnp<tm1Cwe> Tg(Eno2-Prnp)#Aag/Cnrm

Attribute String:

mutant stock, targeted mutation, transgenic

•

Publication

15564479 | J:94220

First Author:	Thackray AM
Year:	2004
Journal:	J Virol
Title:	Accelerated prion disease in the absence of interleukin-10.
Volume:	78
Issue:	24
Pages:	13697-707

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Publication

28275192 | J:241561

First Author:	Bradford BM
Year:	2017
Journal:	J Virol
Title:	Oral Prion Disease Pathogenesis Is Impeded in the Specific Absence of CXCR5-Expressing Dendritic Cells.
Volume:	91
Issue:	10

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Publication

29338055 | J:274039

First Author:	Mercer RCC
Year:	2018
Journal:	PLoS Pathog
Title:	A novel Gerstmann-Sträussler-Scheinker disease mutation defines a precursor for amyloidogenic 8 kDa PrP fragments and reveals N-terminal structural changes shared by other GSS alleles.
Volume:	14
Issue:	1
Pages:	e1006826

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Strain

MGI:5776259 | FVB(129S7)-Tg(Prnp/PRNP*AHQ)EF50Pcg/H

Attribute String:

transgenic, mutant strain

•

Publication

38164158 | J:344429

First Author:	Um JH
Year:	2024
Journal:	Theranostics
Title:	Selective induction of Rab9-dependent alternative mitophagy using a synthetic derivative of isoquinoline alleviates mitochondrial dysfunction and cognitive deficits in Alzheimer's disease models.
Volume:	14
Issue:	1
Pages:	56-74

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Strain

MGI:5014483 | STOCK Prnp<tm1Cwe> Tg(Pcp2-Prnp)F332Zbz/Cnrm

Attribute String:

transgenic, targeted mutation, mutant stock

•

Strain

MGI:5318493 | STOCK Prnp<tm1Cwe> Tg(Prnp)940Zbz/Cnrm

Attribute String:

mutant stock, transgenic

•

Publication

20005821 | J:155809

First Author:	Kim J
Year:	2009
Journal:	Neuron
Title:	Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance.
Volume:	64
Issue:	5
Pages:	632-44

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Strain

MGI:5318501 | STOCK Prnp<tm1Cwe> Tg(Prnp)941Zbz/Cnrm

Attribute String:

transgenic, mutant stock

•

Publication

11487626 | J:70838

First Author:	Ishihara T
Year:	2001
Journal:	J Neurosci
Title:	Attenuated neurodegenerative disease phenotype in tau transgenic mouse lacking neurofilaments.
Volume:	21
Issue:	16
Pages:	6026-35

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Publication

32653673 | J:299301

First Author:	Sharkey LM
Year:	2020
Journal:	Neurobiol Dis
Title:	Modeling UBQLN2-mediated neurodegenerative disease in mice: Shared and divergent properties of wild type and mutant UBQLN2 in phase separation, subcellular localization, altered proteostasis pathways, and selective cytotoxicity.
Volume:	143

Pages:	105016

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Publication

17080199 | J:114572

First Author:	Tesseur I
Year:	2006
Journal:	J Clin Invest
Title:	Deficiency in neuronal TGF-beta signaling promotes neurodegeneration and Alzheimer's pathology.
Volume:	116
Issue:	11
Pages:	3060-9

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Publication

29949744 | J:264778

First Author:	Amadeo A
Year:	2018
Journal:	Neuroscience
Title:	Postnatal Changes in K⁺/Cl^- Cotransporter-2 Expression in the Forebrain of Mice Bearing a Mutant Nicotinic Subunit Linked to Sleep-Related Epilepsy.
Volume:	386

Pages:	91-107

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Strain

MGI:5803983 | B6.Cg-Prnp<tm1Cwe> Tg(Prnp*M128*D177N)FFI-10Rchi/Cnrm

Attribute String:

congenic, mutant strain, targeted mutation, transgenic

•

Strain

MGI:7571101 | B6.Cg-Prnp<tm1Cwe> Tg(Prnp*M128*D177N)FFI-26Rchi/Cnrm

Attribute String:

mutant stock, targeted mutation, transgenic

•

Strain

MGI:5803827 | STOCK Prnp<tm2Edin> Tg(Prnp-PRNP)340Jmto/Cnbc

Attribute String:

mutant stock, targeted mutation, transgenic

•

Genotype

Symbol:	Tg(APPSWE)2576Kha/? Tg(Prnp-ITM2B/APP695*42)A12Emcg/?
Background:	involves: C3H * C57BL/6 * SJL
Zygosity:	cx
Has Mutant Allele:	true

•

Genotype

Symbol:	Tg(Prnp-tTA)F959Sbp/? Tg(tetO-Chrnb2*V287L)H3Gica/?
Background:	involves: 129S7/SvEvBrd * FVB
Zygosity:	cx
Has Mutant Allele:	true

•

Genotype

Symbol:	Cxcr5/Cxcr5 Tg(Itgax-cre)1-1Reiz/? Tg(Prnp)a20Cwe/?
Background:	involves: C57BL/6 * C57BL/6J * CBA
Zygosity:	cn
Has Mutant Allele:	true

•

Publication

36536457 | J:338954

First Author:	Kim DW
Year:	2022
Journal:	Mol Neurodegener
Title:	Amyloid-beta and tau pathologies act synergistically to induce novel disease stage-specific microglia subtypes.
Volume:	17
Issue:	1
Pages:	83

•

Publication

26494278 | J:255120

First Author:	Bien-Ly N
Year:	2015
Journal:	Neuron
Title:	Lack of Widespread BBB Disruption in Alzheimer's Disease Models: Focus on Therapeutic Antibodies.
Volume:	88
Issue:	2
Pages:	289-97

•

Publication

37995685 | J:346146

First Author:	Litvinchuk A
Year:	2024
Journal:	Neuron
Title:	Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist.
Volume:	112
Issue:	3
Pages:	384-403.e8

•

Publication

29346778 | J:324542

First Author:	Friedman BA
Year:	2018
Journal:	Cell Rep
Title:	Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer's Disease Not Evident in Mouse Models.
Volume:	22
Issue:	3
Pages:	832-847

•

Publication

20385796 | J:159279

First Author:	Coomaraswamy J
Year:	2010
Journal:	Proc Natl Acad Sci U S A
Title:	Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease.
Volume:	107
Issue:	17
Pages:	7969-74

•

Publication

19153075 | J:145855

First Author:	Manfredi I
Year:	2009
Journal:	Hum Mol Genet
Title:	Expression of mutant beta2 nicotinic receptors during development is crucial for epileptogenesis.
Volume:	18
Issue:	6
Pages:	1075-88

•

Publication

18694898 | J:140396

First Author:	Stokin GB
Year:	2008
Journal:	Hum Mol Genet
Title:	Amyloid precursor protein-induced axonopathies are independent of amyloid-beta peptides.
Volume:	17
Issue:	22
Pages:	3474-86

•

Publication

17234594 | J:117413

First Author:	Kim J
Year:	2007
Journal:	J Neurosci
Title:	Abeta40 inhibits amyloid deposition in vivo.
Volume:	27
Issue:	3
Pages:	627-33

•

Publication

16039562 | J:101023

First Author:	McGowan E
Year:	2005
Journal:	Neuron
Title:	Abeta42 is essential for parenchymal and vascular amyloid deposition in mice.
Volume:	47
Issue:	2
Pages:	191-199

•

Publication

18202749 | J:131400

First Author:	Wahrle SE
Year:	2008
Journal:	J Clin Invest
Title:	Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease.
Volume:	118
Issue:	2
Pages:	671-82

•

Publication

25706990 | J:226301

First Author:	Brendel M
Year:	2015
Journal:	PLoS One
Title:	Cross-sectional comparison of small animal [18F]-florbetaben amyloid-PET between transgenic AD mouse models.
Volume:	10
Issue:	2
Pages:	e0116678

•

Publication

24806669 | J:211050

First Author:	Kallop DY
Year:	2014
Journal:	J Neurosci
Title:	A death receptor 6-amyloid precursor protein pathway regulates synapse density in the mature CNS but does not contribute to Alzheimer's disease-related pathophysiology in murine models.
Volume:	34
Issue:	19
Pages:	6425-37

•

Publication

21445238 | J:235784

First Author:	Padilla D
Year:	2011
Journal:	PLoS Pathog
Title:	Sheep and goat BSE propagate more efficiently than cattle BSE in human PrP transgenic mice.
Volume:	7
Issue:	3
Pages:	e1001319

•

Publication

25880443 | J:235930

First Author:	Bouybayoune I
Year:	2015
Journal:	PLoS Pathog
Title:	Transgenic fatal familial insomnia mice indicate prion infectivity-independent mechanisms of pathogenesis and phenotypic expression of disease.
Volume:	11
Issue:	4
Pages:	e1004796

•

Publication

37118504 | J:337860

First Author:	Dejanovic B
Year:	2022
Journal:	Nat Aging
Title:	Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer's disease mouse models.
Volume:	2
Issue:	9
Pages:	837-850

•

Publication

27373369 | J:240784

First Author:	Li T
Year:	2016
Journal:	Nat Commun
Title:	The neuritic plaque facilitates pathological conversion of tau in an Alzheimer's disease mouse model.
Volume:	7

Pages:	12082

•

Publication

33891876 | J:306299

First Author:	Bourdenx M
Year:	2021
Journal:	Cell
Title:	Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome.
Volume:	184
Issue:	10
Pages:	2696-2714.e25

•

Publication

33766652 | J:307687

First Author:	William CM
Year:	2021
Journal:	Neurobiol Dis
Title:	Impairment of visual cortical plasticity by amyloid-beta species.
Volume:	154

Pages:	105344

•

Publication

28814543 | J:250614

First Author:	Le Pichon CE
Year:	2017
Journal:	Sci Transl Med
Title:	Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease.
Volume:	9
Issue:	403

•

Publication

29186695 | J:255230

First Author:	Savas JN
Year:	2017
Journal:	Cell Rep
Title:	Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer's Disease-like Pathology.
Volume:	21
Issue:	9
Pages:	2614-2627

•

Publication

22687952 | J:207068

First Author:	Pozueta J
Year:	2013
Journal:	Neuroscience
Title:	Synaptic changes in Alzheimer's disease and its models.
Volume:	251

Pages:	51-65

•

Publication

- | J:232471

First Author:	Veterinary Laboratories Agency
Year:	2009
Journal:	SID 5 Research Project Final Report, DEFRA Project Code SE1753
Title:	Preparation of more sensitive bioassay models for the improved detection, differentiation and diagnosis of the BSE agent

•

Publication

18559949 | J:300211

First Author:	Tamgüney G
Year:	2008
Journal:	J Gen Virol
Title:	Genes contributing to prion pathogenesis.
Volume:	89
Issue:	Pt 7
Pages:	1777-1788

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Publication

23833557 | J:202532

First Author:	Lee JE
Year:	2013
Journal:	Exp Neurobiol
Title:	An update of animal models of Alzheimer disease with a reevaluation of plaque depositions.
Volume:	22
Issue:	2
Pages:	84-95

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Publication

- | J:169366

First Author:	MouseBook^TM
Year:	2005
Journal:	Unpublished
Title:	Information obtained from MouseBook^TM, Medical Research Council Mammalian Genetics Unit, Harwell, UK.

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Publication

- | J:82809

First Author:	European Mouse Mutant Archive
Year:	2003
Journal:	Unpublished
Title:	Information obtained from the European Mouse Mutant Archive (EMMA)

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Publication

- | J:100256

First Author:	The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year:	2005
Journal:	Database Download
Title:	MGI download of GENSAT transgene data

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Search results 1601 to 1652 out of 1652 for Prnp

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