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Search results 201 to 273 out of 273 for Gsr

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Type Details Score
Protein Domain
IPR043197 | Plakin
Type: Family
Description: Plakins are a family of seven cytoskeletal cross-linker proteins (microtubule-actin crosslinking factor 1 (MACF), bullous pemphigoid antigen (BPAG1) desmoplakin, envoplakin, periplakin, plectin, epiplakin) that network the major filaments of the cytoskeleton [].Plakins have been shown to play a diverse range of biological roles. MACF1 and BPAG1 perform cross-linking functions between actin and microtubules and have been shown to play roles in cell migration and microtubule organisation, while plectin cross-links intermediate filaments to microtubules [].Desmoplakin, envoplakin, periplakin and epiplakin are predominately involved in intermediate filament binding. They have been found to play a prominent role in the development of the cornified envelop, in the epidermis. Additional roles have been demonstrated for desmoplakin in myocardium morphogenesis, epidermis development, keratinocyte differentiation, and, along with MACF1, wound healing.Plakins have also been found to be involved in intracellular signalling cascades [].Plakin family members are built from combinations of the following modules: a calponin-type actin-binding domain (ABD); a plakin domain harbouring several α-helical bundles; a heptad-repeat-containing coiled-coil rod domain (CC-rod); a plakin-repeat domain (PRD) generally thought to have intermediate filament (IF)-binding properties, a function that in some cases requires an associated linker (L) subdomain; a spectrin repeat (SR)-containing rod domain; two EF-hand calcium-binding motifs; a Gas2-homology region called the GAR domain; and a domain containing GSR (Gly-Ser-Arg) repeats [].This family represents proteins found predominantly in metazoans.
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Protein
Q80VL5
Organism: Mus musculus/domesticus
Length: 232  
Fragment?: true
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Protein
Q9CV95
Organism: Mus musculus/domesticus
Length: 474  
Fragment?: true
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Protein
E9Q3A6
Organism: Mus musculus/domesticus
Length: 597  
Fragment?: false
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Protein
Q8BVJ3
Organism: Mus musculus/domesticus
Length: 772  
Fragment?: false
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Protein
Q8BV00
Organism: Mus musculus/domesticus
Length: 737  
Fragment?: false
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Protein
Q3TRV6
Organism: Mus musculus/domesticus
Length: 581  
Fragment?: true
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Protein
A0A0A0MQH5
Organism: Mus musculus/domesticus
Length: 369  
Fragment?: true
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Protein
E9PXU3
Organism: Mus musculus/domesticus
Length: 737  
Fragment?: false
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Protein
A0A1D5RLZ3
Organism: Mus musculus/domesticus
Length: 1674  
Fragment?: true
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Protein
Q8C8N4
Organism: Mus musculus/domesticus
Length: 903  
Fragment?: true
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Protein
Q6ZQ59
Organism: Mus musculus/domesticus
Length: 1589  
Fragment?: true
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Protein
Q8R0W0
Organism: Mus musculus/domesticus
Length: 6548  
Fragment?: false
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Protein
Q3V3W8
Organism: Mus musculus/domesticus
Length: 551  
Fragment?: true
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Protein
Q8CEH5
Organism: Mus musculus/domesticus
Length: 510  
Fragment?: true
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Protein
A0A7N9VRC4
Organism: Mus musculus/domesticus
Length: 3458  
Fragment?: false
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Protein
Q69ZZ9
Organism: Mus musculus/domesticus
Length: 3305  
Fragment?: false
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Protein
Q4QQN2
Organism: Mus musculus/domesticus
Length: 455  
Fragment?: true
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Protein
Q3V478
Organism: Mus musculus/domesticus
Length: 176  
Fragment?: true
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Protein
Q6PG96
Organism: Mus musculus/domesticus
Length: 767  
Fragment?: false
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Protein
Q80ZZ3
Organism: Mus musculus/domesticus
Length: 542  
Fragment?: true
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Protein
Q9CYG3
Organism: Mus musculus/domesticus
Length: 393  
Fragment?: false
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Protein
Q8BP77
Organism: Mus musculus/domesticus
Length: 482  
Fragment?: false
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Protein
S4R2A8
Organism: Mus musculus/domesticus
Length: 262  
Fragment?: true
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Protein
S4R2C6
Organism: Mus musculus/domesticus
Length: 259  
Fragment?: true
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Protein
Q80TZ5
Organism: Mus musculus/domesticus
Length: 1485  
Fragment?: true
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Protein
Q8R167
Organism: Mus musculus/domesticus
Length: 289  
Fragment?: true
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Protein
F6RCJ3
Organism: Mus musculus/domesticus
Length: 452  
Fragment?: true
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Protein
F6YKN8
Organism: Mus musculus/domesticus
Length: 544  
Fragment?: true
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Protein
F6RL59
Organism: Mus musculus/domesticus
Length: 349  
Fragment?: true
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Protein
S4R1Y6
Organism: Mus musculus/domesticus
Length: 1638  
Fragment?: true
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Protein
Q5DTZ2
Organism: Mus musculus/domesticus
Length: 1900  
Fragment?: true
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Protein
Q9R269
Organism: Mus musculus/domesticus
Length: 1755  
Fragment?: false
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Protein
Q9D952
Organism: Mus musculus/domesticus
Length: 2035  
Fragment?: false
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Protein
E9Q9J6
Organism: Mus musculus/domesticus
Length: 676  
Fragment?: true
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Protein
Q8C8S5
Organism: Mus musculus/domesticus
Length: 676  
Fragment?: true
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Protein
G5E898
Organism: Mus musculus/domesticus
Length: 1754  
Fragment?: false
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Protein
E9PW24
Organism: Mus musculus/domesticus
Length: 499  
Fragment?: true
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Protein
A0A0R4J223
Organism: Mus musculus/domesticus
Length: 661  
Fragment?: true
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Protein
Q05CR3
Organism: Mus musculus/domesticus
Length: 669  
Fragment?: true
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Protein
A0A0R4J221
Organism: Mus musculus/domesticus
Length: 702  
Fragment?: true
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Protein
E9Q557
Organism: Mus musculus/domesticus
Length: 2883  
Fragment?: false
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Protein
F6Q750
Organism: Mus musculus/domesticus
Length: 4429  
Fragment?: true
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Protein
A0A087WSP0
Organism: Mus musculus/domesticus
Length: 5175  
Fragment?: false
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Protein
E9PZW0
Organism: Mus musculus/domesticus
Length: 2284  
Fragment?: false
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Protein
A0A0R4J218
Organism: Mus musculus/domesticus
Length: 964  
Fragment?: true
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Protein
A0A3B2W7J8
Organism: Mus musculus/domesticus
Length: 1646  
Fragment?: true
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Protein
A0A087WPR7
Organism: Mus musculus/domesticus
Length: 2987  
Fragment?: true
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Protein
F6SHS0
Organism: Mus musculus/domesticus
Length: 2030  
Fragment?: true
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Protein
Q499F9
Organism: Mus musculus/domesticus
Length: 810  
Fragment?: true
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Protein
Q9QXS1
Organism: Mus musculus/domesticus
Length: 4691  
Fragment?: false
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Protein
Q6S388
Organism: Mus musculus/domesticus
Length: 4511  
Fragment?: false
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Protein
F6XCT0
Organism: Mus musculus/domesticus
Length: 1837  
Fragment?: true
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Protein
A0A087WRB8
Organism: Mus musculus/domesticus
Length: 1471  
Fragment?: true
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Protein
A0A571BF93
Organism: Mus musculus/domesticus
Length: 5323  
Fragment?: false
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Protein
Q6S393
Organism: Mus musculus/domesticus
Length: 4534  
Fragment?: false
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Protein
A0A0A0MQA6
Organism: Mus musculus/domesticus
Length: 5328  
Fragment?: false
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Protein
E9QNP1
Organism: Mus musculus/domesticus
Length: 5478  
Fragment?: false
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Protein
A0A571BGC6
Organism: Mus musculus/domesticus
Length: 5309  
Fragment?: false
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Protein
Q6S392
Organism: Mus musculus/domesticus
Length: 4521  
Fragment?: false
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Protein
Q6S387
Organism: Mus musculus/domesticus
Length: 4543  
Fragment?: false
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Protein
F7ACR9
Organism: Mus musculus/domesticus
Length: 5333  
Fragment?: true
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Protein
Q3UPG9
Organism: Mus musculus/domesticus
Length: 1378  
Fragment?: true
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Protein
Q6S385
Organism: Mus musculus/domesticus
Length: 4550  
Fragment?: false
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Protein
E9Q3W4
Organism: Mus musculus/domesticus
Length: 4386  
Fragment?: false
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Protein
Q6S390
Organism: Mus musculus/domesticus
Length: 4449  
Fragment?: false
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Protein
Q91ZU6
Organism: Mus musculus/domesticus
Length: 7393  
Fragment?: false
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Protein
Q9QXZ0
Organism: Mus musculus/domesticus
Length: 7354  
Fragment?: false
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Protein
S4R1P5
Organism: Mus musculus/domesticus
Length: 7717  
Fragment?: false
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Protein
B1ARU4
Organism: Mus musculus/domesticus
Length: 7353  
Fragment?: false
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Protein
E9PVY8
Organism: Mus musculus/domesticus
Length: 7355  
Fragment?: false
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Protein
E9Q9X1
Organism: Mus musculus/domesticus
Length: 7406  
Fragment?: false
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Protein
E9QA63
Organism: Mus musculus/domesticus
Length: 7351  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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Cambridge CB2 3EH, United Kingdom