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Search results 201 to 294 out of 294 for Llgl1

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0.032s
Type Details Score
GXD Expression    
Probe: MGI:3506163
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5539210
Age: embryonic day 15.5
Image: GUDMAP:5438
Specimen Label: GUDMAP:5438
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3724635
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1741222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421295
Age: embryonic day 14.5
Image: MH835; Specimen C1406
Specimen Label: MH835; Specimen C1406
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3506163
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754021
Pattern: Single cells
Stage: TS21
Assay Id: MGI:3507662
Age: embryonic day 13.5
Image: 1
Note: Expression was detected in some cells.
Specimen Label: 1
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724635
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421295
Age: embryonic day 14.5
Image: MH835; Specimen C1406
Specimen Label: MH835; Specimen C1406
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724635
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3599822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421295
Age: embryonic day 14.5
Image: MH835; Specimen C1406
Specimen Label: MH835; Specimen C1406
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506163
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2760523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539210
Age: embryonic day 15.5
Image: GUDMAP:5439
Specimen Label: GUDMAP:5439
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:3506163
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280927
Pattern: Single cells
Stage: TS27
Assay Id: MGI:3507662
Age: postnatal newborn
Image: 2
Note: The tissue was olfactory epithelium and/or bulb. Expression was detected in some cells.
Specimen Label: 2
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3724635
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1833322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421295
Age: embryonic day 14.5
Image: MH835; Specimen C1406
Specimen Label: MH835; Specimen C1406
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:7341461
Assay Type: Immunohistochemistry
Annotation Date: 2022-09-28
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1779022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7341499
Age: embryonic day 14.5
Image: 1A
Note: Highly expressed in the ventral ventricular zone.
Specimen Label: 1A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724635
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1752522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421295
Age: embryonic day 14.5
Image: MH835; Specimen C1406
Specimen Label: MH835; Specimen C1406
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724635
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1821522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421295
Age: embryonic day 14.5
Image: MH835; Specimen C1406
Specimen Label: MH835; Specimen C1406
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724635
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1702122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421295
Age: embryonic day 14.5
Image: MH835; Specimen C1406
Specimen Label: MH835; Specimen C1406
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3506163
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267921
Pattern: Uniform
Stage: TS21
Assay Id: MGI:3507662
Age: embryonic day 13.5
Image: 1
Note: Expression was detected in all cells.
Specimen Label: 1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3506163
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5539210
Age: embryonic day 15.5
Image: GUDMAP:5438
Specimen Label: GUDMAP:5438
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3506163
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5539210
Age: embryonic day 15.5
Image: GUDMAP:5439
Specimen Label: GUDMAP:5439
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3724635
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421295
Age: embryonic day 14.5
Image: MH835; Specimen C1406
Specimen Label: MH835; Specimen C1406
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724635
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1668822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421295
Age: embryonic day 14.5
Image: MH835; Specimen C1406
Specimen Label: MH835; Specimen C1406
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3506163
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Pattern: Single cells
Stage: TS27
Assay Id: MGI:3507662
Age: postnatal newborn
Image: 2
Note: Expression was detected in some cells.
Specimen Label: 2
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3724635
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421295
Age: embryonic day 14.5
Image: MH835; Specimen C1406
Specimen Label: MH835; Specimen C1406
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724635
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1757522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421295
Age: embryonic day 14.5
Image: MH835; Specimen C1406
Specimen Label: MH835; Specimen C1406
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506163
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539210
Age: embryonic day 15.5
Image: GUDMAP:5438
Specimen Label: GUDMAP:5438
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3724635
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738322
Stage: TS22
Assay Id: MGI:5421295
Age: embryonic day 14.5
Specimen Label: MH835; Specimen C1406
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3724635
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1802422
Stage: TS22
Assay Id: MGI:5421295
Age: embryonic day 14.5
Specimen Label: MH835; Specimen C1406
Detected: false
Specimen Num: 1
GXD Expression
Probe: MGI:3724635
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1768022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421295
Age: embryonic day 14.5
Image: MH835; Specimen C1406
Note: Expression was weak in the skull (base and vault).
Specimen Label: MH835; Specimen C1406
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3724635
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:2672022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421295
Age: embryonic day 14.5
Image: MH835; Specimen C1406
Note: Expression was weak in whisker follicle.
Specimen Label: MH835; Specimen C1406
Detected: true
Specimen Num: 1
Publication
First Author: Daynac M
Year: 2018
Journal: Nat Commun
Title: Lgl1 controls NG2 endocytic pathway to regulate oligodendrocyte differentiation and asymmetric cell division and gliomagenesis.
Volume: 9
Issue: 1
Pages: 2862
Publication
First Author: Beattie R
Year: 2017
Journal: Neuron
Title: Mosaic Analysis with Double Markers Reveals Distinct Sequential Functions of Lgl1 in Neural Stem Cells.
Volume: 94
Issue: 3
Pages: 517-533.e3
Publication  
First Author: Zhang T
Year: 2019
Journal: Neuroscience
Title: Loss of Lgl1 Disrupts the Radial Glial Fiber-guided Cortical Neuronal Migration and Causes Subcortical Band Heterotopia in Mice.
Volume: 400
Pages: 132-145
Publication
First Author: Zhang T
Year: 2019
Journal: Genes Brain Behav
Title: Lgl1 deficiency disrupts hippocampal development and impairs cognitive performance in mice.
Volume: 18
Issue: 8
Pages: e12605
Publication
First Author: Hou C
Year: 2014
Journal: Dev Biol
Title: Abnormal cerebellar development and Purkinje cell defects in Lgl1-Pax2 conditional knockout mice.
Volume: 395
Issue: 1
Pages: 167-81
Publication
First Author: Wakabayashi Y
Year: 1998
Journal: Biochem Biophys Res Commun
Title: A novel type of myosin encoded by the mouse deafness gene shaker-2.
Volume: 248
Issue: 3
Pages: 655-9
Publication
First Author: Tomotsune D
Year: 1993
Journal: Nature
Title: A mouse homologue of the Drosophila tumour-suppressor gene l(2)gl controlled by Hox-C8 in vivo.
Volume: 365
Issue: 6441
Pages: 69-72
Publication
First Author: Klezovitch O
Year: 2004
Journal: Genes Dev
Title: Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice.
Volume: 18
Issue: 5
Pages: 559-71
Publication
First Author: Quinlan J
Year: 2007
Journal: Am J Physiol Renal Physiol
Title: LGL1, a novel branching morphogen in developing kidney, is induced by retinoic acid.
Volume: 293
Issue: 4
Pages: F987-93
Publication
First Author: Campbell HD
Year: 2000
Journal: DNA Seq
Title: Fliih, the murine homologue of the Drosophila melanogaster flightless I gene: nucleotide sequence, chromosomal mapping and overlap with Llglh.
Volume: 11
Issue: 1-2
Pages: 29-40
Publication
First Author: Lu YZ
Year: 2020
Journal: Exp Cell Res
Title: Bleomycin induced apical-basal polarity loss in alveolar epithelial cell contributes to experimental pulmonary fibrosis.
Volume: 396
Issue: 1
Pages: 112295
Publication
First Author: Dahan I
Year: 2012
Journal: Mol Biol Cell
Title: The tumor suppressor Lgl1 regulates NMII-A cellular distribution and focal adhesion morphology to optimize cell migration.
Volume: 23
Issue: 4
Pages: 591-601
Publication  
First Author: Vieira V
Year: 2008
Journal: Mol Vis
Title: Differential regulation of Dlg1, Scrib, and Lgl1 expression in a transgenic mouse model of ocular cancer.
Volume: 14
Pages: 2390-403
Publication
First Author: Wakabayashi Y
Year: 1997
Journal: Biochem Biophys Res Commun
Title: Genetic and physical delineation of the region of the mouse deafness mutation shaker-2.
Volume: 234
Issue: 1
Pages: 107-10
Publication
First Author: Kuwabara K
Year: 1994
Journal: Genomics
Title: mgl-1, a mouse homologue of the Drosophila tumor-suppressor gene l(2)gl, maps to chromosome 11.
Volume: 20
Issue: 2
Pages: 337-8
Publication
First Author: Sripathy S
Year: 2011
Journal: Mol Cell Biol
Title: Mammalian Llgl2 is necessary for proper branching morphogenesis during placental development.
Volume: 31
Issue: 14
Pages: 2920-33
Publication
First Author: Stephenson RO
Year: 2010
Journal: Development
Title: Disorganized epithelial polarity and excess trophectoderm cell fate in preimplantation embryos lacking E-cadherin.
Volume: 137
Issue: 20
Pages: 3383-91
Publication
First Author: Probst FJ
Year: 1999
Journal: Genomics
Title: A physical map of the mouse shaker-2 region contains many of the genes commonly deleted in Smith-Magenis syndrome (del17p11.2p11.2).
Volume: 55
Issue: 3
Pages: 348-52
Publication
First Author: Ozçelik M
Year: 2010
Journal: J Neurosci
Title: Pals1 is a major regulator of the epithelial-like polarization and the extension of the myelin sheath in peripheral nerves.
Volume: 30
Issue: 11
Pages: 4120-31
Publication
First Author: Weimer JM
Year: 2009
Journal: Development
Title: MARCKS modulates radial progenitor placement, proliferation and organization in the developing cerebral cortex.
Volume: 136
Issue: 17
Pages: 2965-75
Publication
First Author: Tao H
Year: 2012
Journal: Dev Biol
Title: Nuclear localization of Prickle2 is required to establish cell polarity during early mouse embryogenesis.
Volume: 364
Issue: 2
Pages: 138-48
Publication
First Author: Lepourcelet M
Year: 2005
Journal: Development
Title: Insights into developmental mechanisms and cancers in the mammalian intestine derived from serial analysis of gene expression and study of the hepatoma-derived growth factor (HDGF).
Volume: 132
Issue: 2
Pages: 415-27
Publication
First Author: Yan J
Year: 2007
Journal: Am J Hum Genet
Title: Penetrance of craniofacial anomalies in mouse models of Smith-Magenis syndrome is modified by genomic sequence surrounding Rai1: not all null alleles are alike.
Volume: 80
Issue: 3
Pages: 518-25
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Allele
Name: LLGL1 scribble cell polarity complex component; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication
First Author: Dash BP
Year: 2018
Journal: J Cancer Res Clin Oncol
Title: Diverging impact of cell fate determinants Scrib and Llgl1 on adhesion and migration of hematopoietic stem cells.
Volume: 144
Issue: 10
Pages: 1933-1944
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Allele    
Name: LLGL1 scribble cell polarity complex component; wild type
Allele
Name: LLGL1 scribble cell polarity complex component; targeted mutation 1.1, Valeri Vasioukhin
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: LLGL1 scribble cell polarity complex component; targeted mutation 1, Valeri Vasioukhin
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Allele  
Name: LLGL1 scribble cell polarity complex component; gene trap A007H06, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: LLGL1 scribble cell polarity complex component; gene trap E165H09, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: LLGL1 scribble cell polarity complex component; gene trap PST3174, Mammalian Functional Genomics Centre
Allele Type: Gene trapped
Strain
Attribute String: targeted mutation, mutant stock
Allele  
Name: LLGL1 scribble cell polarity complex component; gene trap IST15074H12, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Genotype
Symbol: Llgl1/Llgl1
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Llgl1/Llgl1 Tg(Pax2-cre)1Akg/?
Background: involves: 129 * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Llgl1/Llgl1 Meox2/Meox2<+>
Background: involves: 129 * 129S4/SvJaeSor * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Mohr J
Year: 2018
Journal: Leukemia
Title: The cell fate determinant Scribble is required for maintenance of hematopoietic stem cell function.
Volume: 32
Issue: 5
Pages: 1211-1221