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Search results 1501 to 1528 out of 1528 for Tfap2a

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Type Details Score
GXD Expression
GXD Expression
Probe: MGI:5563339
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6444460
Age: embryonic day 11.5
Image: 3E/F
Note: Tfap2a and Nkx2-5 were not co-expressed. The flow divider was a part of the Nkx2-5-positive cell population and was present in between the most caudal pharyngeal arch arteries.
Specimen Label: 3E/F
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:7578956
Assay Type: Immunohistochemistry
Annotation Date: 2024-01-31
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1859027
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7578990
Age: postnatal day 0
Image: 2D
Note: Strong expression was detected in the future horizontal cell layer. Extensive overlap between Tfap2a and Tfap2b expression was observed (80% of immunopositive cells). In the outer retina, putative horizontal cells exhibiting strong Tfap2b signal were weakly stained for Tfap2a.
Specimen Label: 2D
Detected: true
Specimen Num: 6
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Protein
P34056
Organism: Mus musculus/domesticus
Length: 437  
Fragment?: false
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Allele
Tfap2a<tm2.1Will> | MGI:5647993
Name: transcription factor AP-2, alpha; targeted mutation 2.1, Trevor Williams
Allele Type: Targeted
Attribute String: Conditional ready, Hypomorph
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Allele
Hhat<Tg(TFAP2A-cre)1Will> | MGI:3038358
Name: hedgehog acyltransferase; transgene insertion 1, Trevor Williams
Allele Type: Transgenic
Attribute String: Null/knockout, Recombinase
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Genotype
Genotype
Symbol: Tfap2a/Tfap2a
Background: involves: 129S1/Sv * Black Swiss
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tfap2a/Tfap2a<+>
Background: involves: 129S1/Sv * Black Swiss
Zygosity: ht
Has Mutant Allele: true
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Protein Coding Gene
MGI:106184 | Npm1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q61937
Organism: Mus musculus/domesticus
Length: 292  
Fragment?: false
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Genotype
Genotype
Symbol: Tfap2a/Tfap2a
Background: involves: 129S1/Sv * Black Swiss
Zygosity: ht
Has Mutant Allele: true
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Publication
24784881 | J:226657
First Author: Callier P
Year: 2014
Journal: PLoS Genet
Title: Loss of function mutation in the palmitoyl-transferase HHAT leads to syndromic 46,XY disorder of sex development by impeding Hedgehog protein palmitoylation and signaling.
Volume: 10
Issue: 5
Pages: e1004340
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Strain
MGI:5523148 | STOCK Hhat<Tg(TFAP2A-cre)1Will>/J
Attribute String: mutant stock, transgenic
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Publication
15987787 | J:99606
First Author: Coumoul X
Year: 2005
Journal: Nucleic Acids Res
Title: Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interference.
Volume: 33
Issue: 11
Pages: e102
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Genotype
Genotype
Symbol: Hhat/Hhat<+> Shh/Shh<+>
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hhat/Hhat
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tfap2a/Tfap2a Hhat/?
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hhat/Hhat<+> Ptch1/Ptch1<+>
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fgf8/Fgf8<+> Tfap2a/Tfap2a
Background: involves: 129P2/OlaHsd * 129S1/Sv * Black Swiss
Zygosity: cx
Has Mutant Allele: true
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Publication
22573176 | J:197770
First Author: McDade SS
Year: 2012
Journal: Nucleic Acids Res
Title: Genome-wide analysis of p63 binding sites identifies AP-2 factors as co-regulators of epidermal differentiation.
Volume: 40
Issue: 15
Pages: 7190-206
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Publication
27923152 | J:241447
 
First Author: Yun K
Year: 2017
Journal: Differentiation
Title: Hydronephrosis in the Wnt5a-ablated kidney is caused by an abnormal ureter-bladder connection.
Volume: 94
Pages: 1-7
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Publication
21913308 | J:187873
First Author: Zhu J
Year: 2012
Journal: Genesis
Title: Cre-mediated recombination can induce apoptosis in vivo by activating the p53 DNA damage-induced pathway.
Volume: 50
Issue: 2
Pages: 102-11
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Publication
28891097 | J:252110
First Author: Iulianella A
Year: 2018
Journal: Dev Dyn
Title: Ventral neural patterning in the absence of a Shh activity gradient from the floorplate.
Volume: 247
Issue: 1
Pages: 170-184
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Hhat/Hhat<+>
Background: involves: 129S4/SvJaeSor
Zygosity: cn
Has Mutant Allele: true
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Publication
22110055 | J:178935
First Author: Kitagaki J
Year: 2011
Journal: Development
Title: FGF8 is essential for formation of the ductal system in the male reproductive tract.
Volume: 138
Issue: 24
Pages: 5369-78
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Hhat/Hhat H2az2/H2az2<+>
Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Publication
25799573 | J:229187
First Author: Kurosaka H
Year: 2015
Journal: PLoS One
Title: Cranial nerve development requires co-ordinated Shh and canonical Wnt signaling.
Volume: 10
Issue: 3
Pages: e0120821
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Publication
23055936 | J:190013
First Author: Dennis JF
Year: 2012
Journal: PLoS Genet
Title: Mutations in Hedgehog acyltransferase (Hhat) perturb Hedgehog signaling, resulting in severe acrania-holoprosencephaly-agnathia craniofacial defects.
Volume: 8
Issue: 10
Pages: e1002927
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Publication
24076664 | J:202828
First Author: Regard JB
Year: 2013
Journal: Nat Med
Title: Activation of Hedgehog signaling by loss of GNAS causes heterotopic ossification.
Volume: 19
Issue: 11
Pages: 1505-12
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