|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 201 to 300 out of 332 for Nipbl

<< First    < Previous  |  Next >    Last >>
0.154s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Gene
570900 | nipbla
Type: gene
Organism: zebrafish
•
•
•
•
•
Gene
794108 | nipblb
Type: gene
Organism: zebrafish
•
•
•
•
•
Allele
Nipbl<Gt(RRS564)Byg> | MGI:4332250
Name: NIPBL cohesin loading factor; gene trap RRS564, BayGenomics
Allele Type: Gene trapped
Attribute String: Null/knockout, Reporter
•
•
•
•
•
Genotype
Genotype
Symbol: Nipbl/Nipbl<+>
Background: involves: 129P2/OlaHsd * CD-1
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Nipbl/Nipbl<+>
Background: involves: 129P2/OlaHsd * C57BL/6J * CD-1
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Publication
28167679 | -
First Author: Bot C
Year: 2017
Journal: J Cell Sci
Title: Independent mechanisms recruit the cohesin loader protein NIPBL to sites of DNA damage.
Volume: 130
Issue: 6
Pages: 1134-1146
•
•
•
•
•
Allele
Nipbl<+> | MGI:3528496
   
Name: NIPBL cohesin loading factor; wild type
•
•
•
•
•
Allele
Nipbl<Gt(OST60593)Lex> | MGI:4167487
 
Name: NIPBL cohesin loading factor; gene trap OST60593, Lexicon Genetics
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(OST169756)Lex> | MGI:4213144
 
Name: NIPBL cohesin loading factor; gene trap OST169756, Lexicon Genetics
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<em1Gpt> | MGI:7303032
Name: NIPBL cohesin loading factor; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
•
•
•
•
•
Allele
Nipbl<Gt(OST56322)Lex> | MGI:4164732
 
Name: NIPBL cohesin loading factor; gene trap OST56322, Lexicon Genetics
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(OST317779)Lex> | MGI:4278192
 
Name: NIPBL cohesin loading factor; gene trap OST317779, Lexicon Genetics
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(OST170981)Lex> | MGI:4213754
 
Name: NIPBL cohesin loading factor; gene trap OST170981, Lexicon Genetics
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(OST261255)Lex> | MGI:4255321
 
Name: NIPBL cohesin loading factor; gene trap OST261255, Lexicon Genetics
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<tm1.2Hpt> | MGI:5636687
Name: NIPBL cohesin loading factor; targeted mutation 1.2, Heiko Peters
Allele Type: Targeted
Attribute String: Null/knockout
•
•
•
•
•
Allele
Nipbl<tm1Fsp> | MGI:6343216
Name: NIPBL cohesin loading factor; targeted mutation 1, Francois Spitz
Allele Type: Targeted
Attribute String: Conditional ready
•
•
•
•
•
Allele
Nipbl<Gt(OST118653)Lex> | MGI:4191326
 
Name: NIPBL cohesin loading factor; gene trap OST118653, Lexicon Genetics
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(OST382740)Lex> | MGI:4301137
 
Name: NIPBL cohesin loading factor; gene trap OST382740, Lexicon Genetics
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(OST396484)Lex> | MGI:4305019
 
Name: NIPBL cohesin loading factor; gene trap OST396484, Lexicon Genetics
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(OST69397)Lex> | MGI:4173204
 
Name: NIPBL cohesin loading factor; gene trap OST69397, Lexicon Genetics
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(OST106116)Lex> | MGI:4185715
 
Name: NIPBL cohesin loading factor; gene trap OST106116, Lexicon Genetics
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(OST194109)Lex> | MGI:4225445
 
Name: NIPBL cohesin loading factor; gene trap OST194109, Lexicon Genetics
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(OST319302)Lex> | MGI:4278963
 
Name: NIPBL cohesin loading factor; gene trap OST319302, Lexicon Genetics
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(OST457078)Lex> | MGI:4324169
 
Name: NIPBL cohesin loading factor; gene trap OST457078, Lexicon Genetics
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(OST134248)Lex> | MGI:4199122
 
Name: NIPBL cohesin loading factor; gene trap OST134248, Lexicon Genetics
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<tm1.1Hpt> | MGI:5638625
Name: NIPBL cohesin loading factor; targeted mutation 1.1, Heiko Peters
Allele Type: Targeted
Attribute String: Conditional ready
•
•
•
•
•
Allele
Nipbl<Gt(OST259679)Lex> | MGI:4254609
 
Name: NIPBL cohesin loading factor; gene trap OST259679, Lexicon Genetics
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(OST139434)Lex> | MGI:4201398
 
Name: NIPBL cohesin loading factor; gene trap OST139434, Lexicon Genetics
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(OST42582)Lex> | MGI:4158038
 
Name: NIPBL cohesin loading factor; gene trap OST42582, Lexicon Genetics
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(RRJ102)Byg> | MGI:4129276
 
Name: NIPBL cohesin loading factor; gene trap RRJ102, BayGenomics
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(OST57035)Lex> | MGI:4165226
 
Name: NIPBL cohesin loading factor; gene trap OST57035, Lexicon Genetics
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(OST215902)Lex> | MGI:4236314
 
Name: NIPBL cohesin loading factor; gene trap OST215902, Lexicon Genetics
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(OST169155)Lex> | MGI:4212846
 
Name: NIPBL cohesin loading factor; gene trap OST169155, Lexicon Genetics
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(OST297500)Lex> | MGI:4269607
 
Name: NIPBL cohesin loading factor; gene trap OST297500, Lexicon Genetics
Allele Type: Gene trapped
•
•
•
•
•
Publication
23967866 | -
First Author: Kuleszewicz K
Year: 2013
Journal: Cell Div
Title: Cohesin loading factor Nipbl localizes to chromosome axes during mammalian meiotic prophase.
Volume: 8
Issue: 1
Pages: 12
•
•
•
•
•
Allele
Nipbl<Gt(IST13648E12)Tigm> | MGI:5180992
 
Name: NIPBL cohesin loading factor; gene trap IST13648E12, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(D072A11)Wrst> | MGI:3883088
 
Name: NIPBL cohesin loading factor; gene trap D072A11, German Gene Trap Consortium
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(312H06)Cmhd> | MGI:4966978
 
Name: NIPBL cohesin loading factor; gene trap 312H06, Centre for Modeling Human Disease
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(IST13742C4)Tigm> | MGI:5186309
 
Name: NIPBL cohesin loading factor; gene trap IST13742C4, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(D072B11)Wrst> | MGI:3883089
 
Name: NIPBL cohesin loading factor; gene trap D072B11, German Gene Trap Consortium
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(IST14086B7)Tigm> | MGI:5206756
 
Name: NIPBL cohesin loading factor; gene trap IST14086B7, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(IST13414G11)Tigm> | MGI:5166930
 
Name: NIPBL cohesin loading factor; gene trap IST13414G11, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(E251A08)Wrst> | MGI:3920429
 
Name: NIPBL cohesin loading factor; gene trap E251A08, German Gene Trap Consortium
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<tm1Smoc> | MGI:7618978
Name: NIPBL cohesin loading factor; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
•
•
•
•
•
Allele
Nipbl<tm1a(EUCOMM)Wtsi> | MGI:4842326
Name: NIPBL cohesin loading factor; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
•
•
•
•
•
Allele
Nipbl<Gt(IST14139A7)Tigm> | MGI:5213831
 
Name: NIPBL cohesin loading factor; gene trap IST14139A7, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(EUCJ0140c07)Hmgu> | MGI:4878240
 
Name: NIPBL cohesin loading factor; gene trap EUCJ0140c07, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(IST14481G7)Tigm> | MGI:5235984
 
Name: NIPBL cohesin loading factor; gene trap IST14481G7, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(IST10038B3)Tigm> | MGI:5145372
 
Name: NIPBL cohesin loading factor; gene trap IST10038B3, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(IST13394C3)Tigm> | MGI:5171024
 
Name: NIPBL cohesin loading factor; gene trap IST13394C3, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(IST14669H6)Tigm> | MGI:5250019
 
Name: NIPBL cohesin loading factor; gene trap IST14669H6, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(IST14094H9)Tigm> | MGI:5207960
 
Name: NIPBL cohesin loading factor; gene trap IST14094H9, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(D057A05)Wrst> | MGI:3908449
 
Name: NIPBL cohesin loading factor; gene trap D057A05, German Gene Trap Consortium
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(IST14725H5)Tigm> | MGI:5254450
 
Name: NIPBL cohesin loading factor; gene trap IST14725H5, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(EUCE00123h12)Hmgu> | MGI:4392727
 
Name: NIPBL cohesin loading factor; gene trap EUCE00123h12, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(EUCE313f02)1.2Hmgu> | MGI:5644813
Name: NIPBL cohesin loading factor; gene trap EUCE313f02, 1.2, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
Attribute String: Null/knockout
•
•
•
•
•
Allele
Nipbl<Gt(EUCE313f02)Hmgu> | MGI:4374347
Name: NIPBL cohesin loading factor; gene trap EUCE313f02, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
Attribute String: Conditional ready, Null/knockout
•
•
•
•
•
Allele
Nipbl<Gt(EUCE00135f05)Hmgu> | MGI:4389842
 
Name: NIPBL cohesin loading factor; gene trap EUCE00135f05, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(IST13845A6)Tigm> | MGI:5188473
 
Name: NIPBL cohesin loading factor; gene trap IST13845A6, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(IST10607H9)Tigm> | MGI:5143189
 
Name: NIPBL cohesin loading factor; gene trap IST10607H9, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(IST13188A6)Tigm> | MGI:5153470
 
Name: NIPBL cohesin loading factor; gene trap IST13188A6, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(P029A06)Wrst> | MGI:4348831
 
Name: NIPBL cohesin loading factor; gene trap P029A06, German Gene Trap Consortium
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(EUCJ0178d03)Hmgu> | MGI:4870986
 
Name: NIPBL cohesin loading factor; gene trap EUCJ0178d03, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(Ayu21-T49)Imeg> | MGI:3923398
 
Name: NIPBL cohesin loading factor; gene trap Ayu21-T49, Institute of Molecular Embryology and Genetics
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(EUCJ0141f07)Hmgu> | MGI:4870843
 
Name: NIPBL cohesin loading factor; gene trap EUCJ0141f07, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(IST14153G11)Tigm> | MGI:5216671
 
Name: NIPBL cohesin loading factor; gene trap IST14153G11, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(IST14151F2)Tigm> | MGI:5216517
 
Name: NIPBL cohesin loading factor; gene trap IST14151F2, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<tm1e(EUCOMM)Wtsi> | MGI:4842460
Name: NIPBL cohesin loading factor; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
•
•
•
•
•
Allele
Nipbl<Gt(EUCJ0178e04)Hmgu> | MGI:4876362
 
Name: NIPBL cohesin loading factor; gene trap EUCJ0178e04, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(P029B06)Wrst> | MGI:4348830
 
Name: NIPBL cohesin loading factor; gene trap P029B06, German Gene Trap Consortium
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(IST13933E3)Tigm> | MGI:5194198
 
Name: NIPBL cohesin loading factor; gene trap IST13933E3, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
•
•
•
•
•
Allele
Nipbl<Gt(EUCE313f02)1.1Hmgu> | MGI:5644433
Name: NIPBL cohesin loading factor; gene trap EUCE313f02, 1.1, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
Attribute String: Conditional ready, Reporter
•
•
•
•
•
Genotype
Genotype
Symbol: Nipbl/Nipbl
Background: involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Nipbl/Nipbl
Background: involves: 129S2/SvPas * C57BL/6 * SJL
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
HT Experiment
GSE203014 | Decreasing Wapl dosage partially corrects transcriptome phenotypes in Nipbl-/+ embryonic mouse brain
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
•
•
•
•
•
DO Term
DOID:0080505 | Cornelia de Lange syndrome 1
•
•
•
•
•
Strain
MGI:6354401 | C57BL/6J-Nipbl<tm1Smoc>/Smoc
Attribute String: congenic, mutant strain, targeted mutation
•
•
•
•
•
Genotype
Genotype
Symbol: Nipbl/Nipbl<+>
Background: involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Nipbl/Nipbl<+>
Background: involves: 129P2/OlaHsd
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Nipbl/Nipbl<+>
Background: involves: 129S2/SvPas * CD-1
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Nipbl/Nipbl<+>
Background: involves: 129P2/OlaHsd * CD-1
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Nipbl/Nipbl<+>
Background: involves: 129P2/OlaHsd * CD-1
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Nipbl/Nipbl<+> Tg(Nanog-cre)#Vlcg/?
Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6NTac * CD-1
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Nipbl/Nipbl<+>
Background: involves: 129 * C57BL/6J * FVB/N
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Nipbl/Nipbl<+>
Background: involves: 129P2/OlaHsd
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Nipbl/Nipbl<+> Tg(Tnnt2-cre)5Blh/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA/2
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Nipbl/Nipbl<+> Tg(Tnnt2-cre)5Blh/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA/2
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Nipbl/Nipbl<+> Tg(Nanog-cre)#Vlcg/?
Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6NTac * CD-1
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Nipbl/Nipbl<+> Nkx2-5/Nkx2-5<+>
Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * CD-1
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Nipbl/Nipbl H2az2/H2az2<+>
Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6J * CBA/J * SJL
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Eif2ak2/Eif2ak2 Nipbl/Nipbl<+>
Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6J * CD-1
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Publication
17965872 | -
First Author: Misulovin Z
Year: 2008
Journal: Chromosoma
Title: Association of cohesin and Nipped-B with transcriptionally active regions of the Drosophila melanogaster genome.
Volume: 117
Issue: 1
Pages: 89-102
•
•
•
•
•
Publication
19797771 | -
First Author: Kogut I
Year: 2009
Journal: Genes Dev
Title: The Scc2/Scc4 cohesin loader determines the distribution of cohesin on budding yeast chromosomes.
Volume: 23
Issue: 19
Pages: 2345-57
•
•
•
•
•
Publication
25715109 | -
First Author: Zakari M
Year: 2015
Journal: Cell Cycle
Title: The SMC loader Scc2 regulates gene expression.
Volume: 14
Issue: 7
Pages: 943
•
•
•
•
•
Publication
22039349 | -
First Author: Muto A
Year: 2011
Journal: PLoS Biol
Title: Multifactorial origins of heart and gut defects in nipbl-deficient zebrafish, a model of Cornelia de Lange Syndrome.
Volume: 9
Issue: 10
Pages: e1001181
•
•
•
•
•
Protein Domain
IPR033031 | Scc2/Nipped-B
Type: Family
Description: This entry represents the Nipped-B protein and its homologues, including Mis4 from fission yeast, Scc2 from budding yeast and Nipbl from zebrafish and Nipped-B from Drosophila. Budding yeast Scc2 is known to be part of the loader for the cohesion to be loaded onto the chromosome []. It has also been shown to regulate gene expression independent of cohesin [].Drosophila melanogaster Nipped-B protein is a chromatin binding protein that is involved in sister chromatid cohesion. Nipped-B and its Mau-2 partner are required for cohesin to associate with chromosomes []. The Drosophila Nipped-B has also been shown to regulate gene expression []. The zebrafish Nipbl has also been shown to regulate transcription. Nipbl has the ability to interact with other molecules such as histone deacetylases, HP-1gamma, and chromatin remodelling factors. It has been suggested that Nipbl is a cohesin-asociated scaffold protein that have functions other than loading cohesin []. Mutations in the human NIPBL (Nipped-B-like) gene cause Cornelia de Lange syndrome 1 (CDLS1), a clinically heterogeneous developmental disorder associated with malformations affecting multiple systems [].
•
•
•
•
•
Publication
19308700 | -
First Author: Dorsett D
Year: 2009
Journal: Chromosome Res
Title: Cohesin, gene expression and development: lessons from Drosophila.
Volume: 17
Issue: 2
Pages: 185-200
•
•
•
•
•
HT Experiment
E-GEOD-60932 | Gene expression changes in limb buds of Nipbl-haploinsufficient mice
Series Id: GSE60932
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom