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Search results 101 to 200 out of 216 for Ubr4

0.037s
Type Details Score
GXD Expression      
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1795022
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Specimen Label: ST73; Specimen C1639
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1832122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Image: ST73; Specimen C1639
Specimen Label: ST73; Specimen C1639
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3090122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Image: ST73; Specimen C1639
Specimen Label: ST73; Specimen C1639
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1738122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Image: ST73; Specimen C1639
Specimen Label: ST73; Specimen C1639
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1738222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Image: ST73; Specimen C1639
Specimen Label: ST73; Specimen C1639
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1842522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Image: ST73; Specimen C1639
Note: Expression was strong in the endocrine system.
Specimen Label: ST73; Specimen C1639
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1706822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Image: ST73; Specimen C1639
Specimen Label: ST73; Specimen C1639
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3599822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Image: ST73; Specimen C1639
Specimen Label: ST73; Specimen C1639
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Specimen Label: ST73; Specimen C1639
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1842622
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Specimen Label: ST73; Specimen C1639
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1610422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Image: ST73; Specimen C1639
Specimen Label: ST73; Specimen C1639
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1610522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Image: ST73; Specimen C1639
Specimen Label: ST73; Specimen C1639
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1668822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Image: ST73; Specimen C1639
Specimen Label: ST73; Specimen C1639
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1733122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Image: ST73; Specimen C1639
Specimen Label: ST73; Specimen C1639
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3274322
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Specimen Label: ST73; Specimen C1639
Detected: false
Specimen Num: 1
GXD Expression
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1876522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Image: ST73; Specimen C1639
Note: Expression was detected in the immune system.
Specimen Label: ST73; Specimen C1639
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1853522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Image: ST73; Specimen C1639
Specimen Label: ST73; Specimen C1639
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1752322
Pattern: Ubiquitous
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Image: ST73; Specimen C1639
Specimen Label: ST73; Specimen C1639
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3272922
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Note: Expression was not detected in the skeleton (limbs, shoulder, hip).
Specimen Label: ST73; Specimen C1639
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3557722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Image: ST73; Specimen C1639
Specimen Label: ST73; Specimen C1639
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3276322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Image: ST73; Specimen C1639
Note: Expression was weak in the face/soft tissues.
Specimen Label: ST73; Specimen C1639
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1802422
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Specimen Label: ST73; Specimen C1639
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1768022
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Note: Expression was not detected in the skull (base and vault).
Specimen Label: ST73; Specimen C1639
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1721422
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Specimen Label: ST73; Specimen C1639
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1674822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Image: ST73; Specimen C1639
Specimen Label: ST73; Specimen C1639
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1741222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Image: ST73; Specimen C1639
Specimen Label: ST73; Specimen C1639
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1745822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Image: ST73; Specimen C1639
Specimen Label: ST73; Specimen C1639
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1752422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Image: ST73; Specimen C1639
Specimen Label: ST73; Specimen C1639
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1752522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Image: ST73; Specimen C1639
Specimen Label: ST73; Specimen C1639
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1876922
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Image: ST73; Specimen C1639
Specimen Label: ST73; Specimen C1639
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5309595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:2672022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422961
Age: embryonic day 14.5
Image: ST73; Specimen C1639
Note: Expression was weak in whisker follicle.
Specimen Label: ST73; Specimen C1639
Detected: true
Specimen Num: 1
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691857
Age: postnatal adult
Image: MRC Harwell_1467913
Note: kidney
Specimen Label: MRC Harwell_1467913
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691857
Age: postnatal adult
Image: MRC Harwell_1467914
Specimen Label: MRC Harwell_1467914
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:7536903
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608615
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:7536907
Age: embryonic day 9.5
Note: Prominent expression in yolk sac endoderm
Specimen Label: 1B +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7536903
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1608515
Stage: TS15
Assay Id: MGI:7536907
Age: embryonic day 9.5
Specimen Label: 1B UBR4-/-
Detected: false
Specimen Num: 2
Protein
Organism: Mus musculus/domesticus
Length: 5180  
Fragment?: false
Publication
First Author: Nakaya T
Year: 2013
Journal: PLoS One
Title: p600 Plays Essential Roles in Fetal Development.
Volume: 8
Issue: 6
Pages: e66269
Publication
First Author: Belzil C
Year: 2014
Journal: Biol Open
Title: p600 regulates spindle orientation in apical neural progenitors and contributes to neurogenesis in the developing neocortex.
Volume: 3
Issue: 6
Pages: 475-85
Publication
First Author: Shim SY
Year: 2008
Journal: J Neurosci
Title: Protein 600 is a microtubule/endoplasmic reticulum-associated protein in CNS neurons.
Volume: 28
Issue: 14
Pages: 3604-14
Publication    
First Author: Niu F
Year: 2022
Journal: Elife
Title: The m6A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells.
Volume: 11
Publication
First Author: Okazaki N
Year: 2002
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 9
Issue: 5
Pages: 179-88
Publication      
First Author: Overbeek PA
Year: 2011
Journal: MGI Direct Data Submission
Title: Direct Data Submission for Overbeek Lentiviral Transgenic Lines
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Cobellis G
Year: 2005
Journal: Nucleic Acids Res
Title: Tagging genes with cassette-exchange sites.
Volume: 33
Issue: 4
Pages: e44
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Protein
Organism: Mus musculus/domesticus
Length: 469  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 2021  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 5208  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 5156  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 474  
Fragment?: false
UniProt Feature
Begin: 1
Description: E3 ubiquitin-protein ligase UBR4
Type: chain
End: 5180
Protein
Organism: Mus musculus/domesticus
Length: 2065  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 204  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1301  
Fragment?: true
Interaction Experiment
Description: The ubiquitin ligase Ubr4 controls stability of podocin/MEC-2 supercomplexes.
Publication
First Author: Hong JH
Year: 2015
Journal: Mol Cell Proteomics
Title: KCMF1 (potassium channel modulatory factor 1) Links RAD6 to UBR4 (ubiquitin N-recognin domain-containing E3 ligase 4) and lysosome-mediated degradation.
Volume: 14
Issue: 3
Pages: 674-85
Publication
First Author: Morrison J
Year: 2013
Journal: PLoS Pathog
Title: Dengue virus co-opts UBR4 to degrade STAT2 and antagonize type I interferon signaling.
Volume: 9
Issue: 3
Pages: e1003265
DO Term
Publication
First Author: Tasaki T
Year: 2005
Journal: Mol Cell Biol
Title: A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons.
Volume: 25
Issue: 16
Pages: 7120-36
Publication
First Author: Ashton-Beaucage D
Year: 2016
Journal: PLoS Biol
Title: The Deubiquitinase USP47 Stabilizes MAPK by Counteracting the Function of the N-end Rule ligase POE/UBR4 in Drosophila.
Volume: 14
Issue: 8
Pages: e1002539
Protein Domain
Type: Domain
Description: This entry represents the N-terminal domain of E3 ubiquitin-protein ligases UBR4 (POE or PUSHOVER in Drosophila) from animals. UBR4 is a component of the N-rule pathway, identified as noncanonical N-recognins implicated in bulk lysosomal degradation and autophagy. Proteins containing this domain are extraordinarily large proteins that recognise and bind to proteins with N-terminal destabilising residues according to the N-end rule leading them to their ubiquitination and degradation. These proteins share a UBR box with others E3-ligases UBR box proteins, but UBR4 lacks the ubiquitylation domain, suggesting that it may interact with other catalytic proteins [, , ].
Publication
First Author: Nakatani Y
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: p600, a unique protein required for membrane morphogenesis and cell survival.
Volume: 102
Issue: 42
Pages: 15093-8
Publication
First Author: Gil P
Year: 2001
Journal: Genes Dev
Title: BIG: a calossin-like protein required for polar auxin transport in Arabidopsis.
Volume: 15
Issue: 15
Pages: 1985-97
Publication
First Author: Li HM
Year: 1994
Journal: Genes Dev
Title: Arabidopsis mutants define downstream branches in the phototransduction pathway.
Volume: 8
Issue: 3
Pages: 339-49
Publication
First Author: Ruegger M
Year: 1997
Journal: Plant Cell
Title: Reduced naphthylphthalamic acid binding in the tir3 mutant of Arabidopsis is associated with a reduction in polar auxin transport and diverse morphological defects.
Volume: 9
Issue: 5
Pages: 745-57