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Search results 1301 to 1357 out of 1357 for Egr2

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Type Details Score
Genotype
Genotype
Symbol: Egr2/Egr2
Background: B6.Cg-Egr2
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0110195 | Charcot-Marie-Tooth disease type 4E
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GXD Expression
GXD Expression
Probe: MGI:5436064
Assay Type: RNA in situ
Annotation Date: 2012-09-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3282012
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:5436256
Age: embryonic day 8.0
Image: 1H
Note: The stripes of expression in prospective rhombomeres 3 and 5 broadened and formed sharp boundaries. The domains coincided with Egr2 (Krox-20 lacZ staining). Expression was downregulated in rhombomere 4, but persisted at low level in 2 and dorsally in 6.
Specimen Label: 1H
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
Probe: MGI:17719
Assay Type: RNA in situ
Annotation Date: 1999-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608911
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:1335751
Age: embryonic day 7.75
Image: 2.B
Note: A broad domain of expression is seen in the hindbrain. Higher levels of expression are coincident with the domain of Egr2 (Krox20) expression; lower levels extend to a boundary in the posterior hindbrain.
Specimen Label: 2.B
Detected: true
Specimen Num: 2
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Allele
Rr102<tm1.1Ics> | MGI:6336128
Name: regulatory region 102; targeted mutation 1.1, Mouse Clinical Institute
Allele Type: Targeted
Attribute String: Conditional ready, Modified regulatory region
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Allele
Rr102<tm1.2Ics> | MGI:6336135
Name: regulatory region 102; targeted mutation 1.2, Mouse Clinical Institute
Allele Type: Targeted
Attribute String: Modified regulatory region
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Protein Domain
IPR000976 | Wilms_tumour_N
Type: Domain
Description: Wilm's tumour (WT) is an embryonal malignancy of the kidney, affecting around 1 in 10,000 infants. It occurs in both sporadic and hereditary forms. Inactivation of WT1 is one of the causes of Wilm's tumour. Defects in the WT1 gene are also associated with Denys-Drash Syndrome (DDS), which is characterised by typical nephropathy and genital abnormalities. The WT1 gene product shows similarity to the zinc fingers of the mammalian growth regulated EGR1 and EGR2 proteins [, , , ].
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Publication
30535360 | J:274585
First Author: Belin S
Year: 2019
Journal: Hum Mol Genet
Title: Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy.
Volume: 28
Issue: 8
Pages: 1260-1273
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Genotype
Genotype
Symbol: Rr102/Rr102
Background: involves: C57BL/6 * DBA/2
Zygosity: hm
Has Mutant Allele: true
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Protein Domain
IPR017987 | Wilms_tumour
Type: Family
Description: Wilm's tumour (WT) is an embryonal malignancy of the kidney, affecting around 1 in 10,000 infants. It occurs in both sporadic and hereditary forms. Inactivation of WT1 is one of the causes of Wilm's tumour. Defects in the WT1 gene are also associated with Denys-Drash Syndrome (DDS), which is characterised by typical nephropathy and genital abnormalities. The WT1 gene product shows similarity to the zinc fingers of the mammalian growth regulated EGR1 and EGR2 proteins [, , , ].This entry represents a Wilm's tumour protein.
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Allele
Tg(PMP22/Hspa1a-luc)DJosv | MGI:6304252
Name: transgene insertion D, John Svaren
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(PMP22/Hspa1a-luc)#Josv | MGI:6304004
Name: transgene insertion, John Svaren
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(PMP22/Hspa1a-luc)EJosv | MGI:6304253
Name: transgene insertion E, John Svaren
Allele Type: Transgenic
Attribute String: Reporter
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Publication
1671709 | J:11004
First Author: Buckler AJ
Year: 1991
Journal: Mol Cell Biol
Title: Isolation, characterization, and expression of the murine Wilms' tumor gene (WT1) during kidney development.
Volume: 11
Issue: 3
Pages: 1707-12
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Publication
8393820 | -
First Author: Rauscher FJ 3rd
Year: 1993
Journal: FASEB J
Title: The WT1 Wilms tumor gene product: a developmentally regulated transcription factor in the kidney that functions as a tumor suppressor.
Volume: 7
Issue: 10
Pages: 896-903
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Publication
2154702 | -
First Author: Gessler M
Year: 1990
Journal: Nature
Title: Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping.
Volume: 343
Issue: 6260
Pages: 774-8
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Publication
1317572 | -
First Author: Little MH
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: Zinc finger point mutations within the WT1 gene in Wilms tumor patients.
Volume: 89
Issue: 11
Pages: 4791-5
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Publication
25185189 | J:217913
First Author: Jiang Y
Year: 2014
Journal: Cancer Discov
Title: Tracing the roots of cancer evolution.
Volume: 4
Issue: 9
Pages: 995-7
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Genotype
Genotype
Symbol: Rr102/Rr102<+> Rr111/Rr111<+>
Background: involves: C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Publication
10755616 | J:77778
First Author: Rengarajan J
Year: 2000
Journal: Immunity
Title: Sequential involvement of NFAT and Egr transcription factors in FasL regulation.
Volume: 12
Issue: 3
Pages: 293-300
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Publication
1906159 | J:49519
First Author: Patwardhan S
Year: 1991
Journal: Oncogene
Title: EGR3, a novel member of the Egr family of genes encoding immediate-early transcription factors.
Volume: 6
Issue: 6
Pages: 917-28
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Publication
21057508 | J:166894
First Author: He Y
Year: 2010
Journal: Nat Neurosci
Title: Yy1 as a molecular link between neuregulin and transcriptional modulation of peripheral myelination.
Volume: 13
Issue: 12
Pages: 1472-80
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HT Experiment
E-GEOD-14242 | Novel Regulators of Fgf23 Expression and Mineralization in Hyp Bone
Series Id: GSE14242
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
9731539 | J:49575
First Author: Tourtellotte WG
Year: 1998
Journal: Nat Genet
Title: Sensory ataxia and muscle spindle agenesis in mice lacking the transcription factor Egr3.
Volume: 20
Issue: 1
Pages: 87-91
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Publication
24344267 | J:206291
First Author: Bedel R
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Effective functional maturation of invariant natural killer T cells is constrained by negative selection and T-cell antigen receptor affinity.
Volume: 111
Issue: 1
Pages: E119-28
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Publication
19556340 | J:225037
First Author: Liu S
Year: 2009
Journal: Mol Endocrinol
Title: Novel regulators of Fgf23 expression and mineralization in Hyp bone.
Volume: 23
Issue: 9
Pages: 1505-18
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Publication
38311982 | J:345924
First Author: Hong J
Year: 2024
Journal: Glia
Title: PMP2 regulates myelin thickening and ATP production during remyelination.
Volume: 72
Issue: 5
Pages: 885-898
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Publication
28970470 | J:254773
First Author: Märklin M
Year: 2017
Journal: Nat Commun
Title: NFAT2 is a critical regulator of the anergic phenotype in chronic lymphocytic leukaemia.
Volume: 8
Issue: 1
Pages: 755
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Publication
21925573 | J:182810
 
First Author: Li C
Year: 2011
Journal: Neuroscience
Title: Microarray analysis of gene expression changes in the brains of NR2B-induced memory-enhanced mice.
Volume: 197
Pages: 121-31
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Publication
10866682 | J:63084
First Author: Tourtellotte WG
Year: 2000
Journal: Mol Cell Biol
Title: Functional compensation by Egr4 in Egr1-dependent luteinizing hormone regulation and Leydig cell steroidogenesis.
Volume: 20
Issue: 14
Pages: 5261-8
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Publication
35029277 | J:343025
First Author: Hu Q
Year: 2022
Journal: Diabetes
Title: Obesity-Induced miR-455 Upregulation Promotes Adaptive Pancreatic β-Cell Proliferation Through the CPEB1/CDKN1B Pathway.
Volume: 71
Issue: 3
Pages: 394-411
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Publication
28282643 | J:268823
 
First Author: Hastings KT
Year: 2017
Journal: Mol Immunol
Title: Nab2 maintains thymus cellularity with aging and stress.
Volume: 85
Pages: 185-195
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Publication
22302795 | J:181350
First Author: Hung H
Year: 2012
Journal: J Neurosci
Title: The nucleosome remodeling and deacetylase chromatin remodeling (NuRD) complex is required for peripheral nerve myelination.
Volume: 32
Issue: 5
Pages: 1517-27
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Publication
25824147 | J:251061
First Author: Tang Y
Year: 2015
Journal: Cardiovasc Res
Title: MicroRNA-150 protects the mouse heart from ischaemic injury by regulating cell death.
Volume: 106
Issue: 3
Pages: 387-97
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Publication
26300473 | J:251647
 
First Author: Torres OV
Year: 2015
Journal: Sci Rep
Title: CAMKII-conditional deletion of histone deacetylase 2 potentiates acute methamphetamine-induced expression of immediate early genes in the mouse nucleus accumbens.
Volume: 5
Pages: 13396
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Publication
17959798 | J:127040
First Author: Ryu EJ
Year: 2007
Journal: J Neurosci
Title: Misexpression of Pou3f1 results in peripheral nerve hypomyelination and axonal loss.
Volume: 27
Issue: 43
Pages: 11552-9
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Publication
18433738 | J:136673
 
First Author: Benturquia N
Year: 2008
Journal: Brain Res
Title: Involvement of D1 dopamine receptor in MDMA-induced locomotor activity and striatal gene expression in mice.
Volume: 1211
Pages: 1-5
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Publication
21573063 | J:172431
First Author: Shieh JT
Year: 2011
Journal: PLoS One
Title: Elevated miR-499 levels blunt the cardiac stress response.
Volume: 6
Issue: 5
Pages: e19481
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Publication
25535333 | J:224297
First Author: Salotti J
Year: 2015
Journal: Mol Cell Biol
Title: An Arf-Egr-C/EBPβ pathway linked to ras-induced senescence and cancer.
Volume: 35
Issue: 5
Pages: 866-83
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Publication
28831138 | J:255793
First Author: Sun JJ
Year: 2017
Journal: Sci Rep
Title: Embryonic hindbrain patterning genes delineate distinct cardio-respiratory and metabolic homeostatic populations in the adult.
Volume: 7
Issue: 1
Pages: 9117
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Publication
31076725 | J:308375
First Author: Zhang X
Year: 2020
Journal: Cell Mol Immunol
Title: TRAF3IP3 at the trans-Golgi network regulates NKT2 maturation via the MEK/ERK signaling pathway.
Volume: 17
Issue: 4
Pages: 395-406
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Protein
P22561
Organism: Mus musculus/domesticus
Length: 449  
Fragment?: false
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Protein
Q199A7
Organism: Mus musculus/domesticus
Length: 305  
Fragment?: false
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Protein
A2A404
Organism: Mus musculus/domesticus
Length: 288  
Fragment?: false
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Protein
A2A400
Organism: Mus musculus/domesticus
Length: 406  
Fragment?: true
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Protein
F6VXG5
Organism: Mus musculus/domesticus
Length: 360  
Fragment?: true
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Protein
F6Y2T6
Organism: Mus musculus/domesticus
Length: 517  
Fragment?: false
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Protein
A2A405
Organism: Mus musculus/domesticus
Length: 302  
Fragment?: false
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Protein
A2A401
Organism: Mus musculus/domesticus
Length: 406  
Fragment?: true
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Publication
17254333 | J:160655
 
First Author: Calella AM
Year: 2007
Journal: Neural Dev
Title: Neurotrophin/Trk receptor signaling mediates C/EBPalpha, -beta and NeuroD recruitment to immediate-early gene promoters in neuronal cells and requires C/EBPs to induce immediate-early gene transcription.
Volume: 2
Pages: 4
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Publication
35002622 | J:317693
 
First Author: Desouza LA
Year: 2021
Journal: Front Mol Neurosci
Title: The Hallucinogenic Serotonin2A Receptor Agonist, 2,5-Dimethoxy-4-Iodoamphetamine, Promotes cAMP Response Element Binding Protein-Dependent Gene Expression of Specific Plasticity-Associated Genes in the Rodent Neocortex.
Volume: 14
Pages: 790213
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Publication
28096300 | J:243617
First Author: Mu C
Year: 2017
Journal: J Leukoc Biol
Title: Enhanced suppression of polyclonal CD8+25+ regulatory T cells via exosomal arming of antigen-specific peptide/MHC complexes.
Volume: 101
Issue: 5
Pages: 1221-1231
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Publication
24023893 | J:205929
First Author: Rondahl V
Year: 2013
Journal: PLoS One
Title: Lrig2-deficient mice are protected against PDGFB-induced glioma.
Volume: 8
Issue: 9
Pages: e73635
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Publication
38566990 | J:347089
 
First Author: Fujikawa Y
Year: 2024
Journal: Front Immunol
Title: Myeloid-derived suppressor cell-derived osteoclasts with bone resorption capacity in the joints of arthritic SKG mice.
Volume: 15
Pages: 1168323
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Publication
- | J:82809
     
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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