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Search results 101 to 200 out of 248 for Ptk2b

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Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:6383968
Assay Type: Western blot
Annotation Date: 2020-01-09
Strength: Present
Sex: Female
Emaps: EMAPS:3575528
Stage: TS28
Assay Id: MGI:6383972
Age: postnatal adult
Image: 1
Specimen Label: MII oocytes
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:6383971
Assay Type: RT-PCR
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:6383973
Age: embryonic day 1.0
Image: 1
Specimen Label: 2-cell
Detected: true
Specimen Num: 2
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:5301873
Assay Type: RT-PCR
Annotation Date: 2012-01-19
Strength: Present
Sex: Male
Emaps: EMAPS:1738319
Stage: TS19
Assay Id: MGI:5301994
Age: embryonic day 11.5
Image: 1
Specimen Label: XY
Detected: true
Specimen Num: 2
•
•
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:5301873
Assay Type: RT-PCR
Annotation Date: 2012-01-19
Strength: Present
Sex: Female
Emaps: EMAPS:1738319
Stage: TS19
Assay Id: MGI:5301994
Age: embryonic day 11.5
Image: 1
Specimen Label: XX
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5301873
Assay Type: RT-PCR
Annotation Date: 2012-01-19
Strength: Present
Sex: Female
Emaps: EMAPS:1796220
Stage: TS20
Assay Id: MGI:5301994
Age: embryonic day 12.5
Image: 1
Specimen Label: XX
Detected: true
Specimen Num: 10
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•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5301873
Assay Type: RT-PCR
Annotation Date: 2012-01-19
Strength: Present
Sex: Female
Emaps: EMAPS:1796221
Stage: TS21
Assay Id: MGI:5301994
Age: embryonic day 13.5
Image: 1
Specimen Label: XX
Detected: true
Specimen Num: 11
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5301873
Assay Type: RT-PCR
Annotation Date: 2012-01-19
Strength: Present
Sex: Female
Emaps: EMAPS:1796222
Stage: TS22
Assay Id: MGI:5301994
Age: embryonic day 14.5
Image: 1
Specimen Label: XX
Detected: true
Specimen Num: 12
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•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5301873
Assay Type: RT-PCR
Annotation Date: 2012-01-19
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:5301994
Age: embryonic day 15.5
Image: 1
Specimen Label: XX
Detected: true
Specimen Num: 13
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•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5301873
Assay Type: RT-PCR
Annotation Date: 2012-01-19
Strength: Present
Sex: Female
Emaps: EMAPS:1796224
Stage: TS24
Assay Id: MGI:5301994
Age: embryonic day 16.5
Image: 1
Specimen Label: XX
Detected: true
Specimen Num: 14
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5301873
Assay Type: RT-PCR
Annotation Date: 2012-01-20
Strength: Present
Sex: Female
Emaps: EMAPS:1796220
Stage: TS20
Assay Id: MGI:5302112
Age: embryonic day 12.5
Image: 3
Specimen Label: XX +/+
Detected: true
Specimen Num: 3
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•
•
•
GXD Expression
GXD Expression
Probe: MGI:6383968
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Pattern: Regionally restricted
Stage: TS03
Assay Id: MGI:6383975
Age: embryonic day 2.0
Image: 3C2/C
Note: Expression in nucleus and cytoplasm. Expression uniformly distributed throughout cytoplasm.
Specimen Label: 3C2/C
Detected: true
Specimen Num: 3
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•
•
•
GXD Expression
GXD Expression
Probe: MGI:6383970
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Pattern: Regionally restricted
Stage: TS03
Assay Id: MGI:6383976
Age: embryonic day 2.0
Image: 4B2/B
Note: Expression increasingly weakened until the morula stage. Expression throughout cytoplasm. Punctate distribution of expression, presented as many points or peaches.
Specimen Label: 4B2/B
Detected: true
Specimen Num: 2
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•
•
•
GXD Expression
GXD Expression
Probe: MGI:6383968
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160331
Pattern: Regionally restricted
Stage: TS01
Assay Id: MGI:6383975
Age: embryonic day 0.5
Image: 3A2/A
Note: Expression in nucleus and cytoplasm. Expression in cytoplasm not evenly distributed, but aggregated as many tiny spots.
Specimen Label: 3A2/A
Detected: true
Specimen Num: 1
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•
•
•
GXD Expression
GXD Expression
Probe: MGI:6383968
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318653
Pattern: Regionally restricted
Stage: TS03
Assay Id: MGI:6383975
Age: embryonic day 2.5
Image: 3D2/D
Note: Expression in nucleus and cytoplasm. Expression in cytoplasm not evenly distributed, but aggregated as many tiny spots.
Specimen Label: 3D2/D
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6383970
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318653
Pattern: Regionally restricted
Stage: TS03
Assay Id: MGI:6383976
Age: embryonic day 2.5
Image: 4C2/C
Note: Expression increasingly weakened until the morula stage. Expression throughout cytoplasm. Punctate distribution of expression, presented as many points or peaches.
Specimen Label: 4C2/C
Detected: true
Specimen Num: 3
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5301887
Assay Type: RNA in situ
Annotation Date: 2012-01-19
Strength: Present
Sex: Male
Emaps: EMAPS:2909820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5302047
Age: embryonic day 12.5
Image: 1D XY 12.5
Note: Expression was restricted to the testis cords.
Specimen Label: 1D XY 12.5
Detected: true
Specimen Num: 3
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•
•
•
GXD Expression
GXD Expression
Probe: MGI:5301887
Assay Type: RNA in situ
Annotation Date: 2012-01-19
Strength: Present
Sex: Male
Emaps: EMAPS:2909821
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:5302047
Age: embryonic day 13.5
Image: 1D XY 13.5
Note: Expression was restricted to the testis cords.
Specimen Label: 1D XY 13.5
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5302197
Assay Type: Immunohistochemistry
Annotation Date: 2012-01-20
Strength: Strong
Sex: Male
Emaps: EMAPS:2909821
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5302231
Age: embryonic day 13.5
Image: 4B
Specimen Label: 4B
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5302197
Assay Type: Immunohistochemistry
Annotation Date: 2012-01-20
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1610528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5302231
Age: postnatal
Specimen Label: not shown
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5301887
Assay Type: RNA in situ
Annotation Date: 2012-01-19
Strength: Absent
Sex: Male
Emaps: EMAPS:1685717
Stage: TS17
Assay Id: MGI:5302047
Age: embryonic day 10.5
Image: 1D XY 10.5
Specimen Label: 1D XY 10.5
Detected: false
Specimen Num: 1
•
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5301887
Assay Type: RNA in situ
Annotation Date: 2012-01-19
Strength: Absent
Sex: Female
Emaps: EMAPS:1685717
Stage: TS17
Assay Id: MGI:5302047
Age: embryonic day 10.5
Image: 1D XX 10.5
Specimen Label: 1D XX 10.5
Detected: false
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6383968
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360354
Pattern: Regionally restricted
Stage: TS04
Assay Id: MGI:6383975
Age: embryonic day 3.5
Image: 3G2/G
Note: No expression in cell nuclei. Expression distributed throughout cytoplasm. Expression in cytoplasm not evenly distributed, but aggregated as many tiny spots.
Specimen Label: 3G2/G
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6383968
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360355
Pattern: Regionally restricted
Stage: TS05
Assay Id: MGI:6383975
Age: embryonic day 4.0
Image: 3H2/H
Note: No expression in cell nuclei. Expression distributed throughout cytoplasm. Expression in cytoplasm not evenly distributed, but aggregated as many tiny spots. Expression in gaps of trophoblast cells.
Specimen Label: 3H2/H
Detected: true
Specimen Num: 8
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6383970
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360354
Pattern: Regionally restricted
Stage: TS04
Assay Id: MGI:6383976
Age: embryonic day 3.5
Image: 4E2/E
Note: Expression in perinuclear region and joint of cells. No expression in nuclei.
Specimen Label: 4E2/E
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6383968
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160403
Pattern: Regionally restricted
Stage: TS03
Assay Id: MGI:6383975
Age: embryonic day 3.0
Image: 3E2/E
Note: Expression in nucleus and cytoplasm. Expression in cytoplasm not evenly distributed, but aggregated as many tiny spots.
Specimen Label: 3E2/E
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6383968
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160404
Pattern: Regionally restricted
Stage: TS04
Assay Id: MGI:6383975
Age: embryonic day 3.0
Image: 3F2/F
Note: Expression in nucleus and cytoplasm. Expression in cytoplasm not evenly distributed, but aggregated as many tiny spots.
Specimen Label: 3F2/F
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6383970
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160404
Pattern: Regionally restricted
Stage: TS04
Assay Id: MGI:6383976
Age: embryonic day 3.0
Image: 4D2/D
Note: Expression increasingly weakened until the morula stage. Expression in the perinuclear region.
Specimen Label: 4D2/D
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5301887
Assay Type: RNA in situ
Annotation Date: 2012-01-19
Strength: Present
Sex: Male
Emaps: EMAPS:1797221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5302047
Age: embryonic day 13.5
Image: 2E
Specimen Label: 2E
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5301887
Assay Type: RNA in situ
Annotation Date: 2012-01-19
Strength: Present
Sex: Male
Emaps: EMAPS:1797221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5302047
Age: embryonic day 13.5
Image: 2F
Specimen Label: 2F
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5302197
Assay Type: Immunohistochemistry
Annotation Date: 2012-01-20
Strength: Present
Sex: Male
Emaps: EMAPS:1797221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5302231
Age: embryonic day 13.5
Image: 4B
Note: High expression levels within in somatic cells of the testis cords.
Specimen Label: 4B
Detected: true
Specimen Num: 1
•
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•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5302197
Assay Type: Immunohistochemistry
Annotation Date: 2012-01-20
Strength: Absent
Sex: Male
Emaps: EMAPS:1797220
Stage: TS20
Assay Id: MGI:5302231
Age: embryonic day 12.5
Specimen Label: not shown
Detected: false
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6383968
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Pattern: Regionally restricted
Stage: TS02
Assay Id: MGI:6383975
Age: embryonic day 1.0
Image: 3B2/B
Note: Expression in nucleus and cytoplasm. Expression in cytoplasm not evenly distributed, but aggregated as many tiny spots.Expression also detected in cell junctions.
Specimen Label: 3B2/B
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6383970
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Pattern: Regionally restricted
Stage: TS02
Assay Id: MGI:6383976
Age: embryonic day 1.0
Image: 4A2/A
Note: Expression particularly in joints of the two cells and this nuclei, but not in nucleoli.
Specimen Label: 4A2/A
Detected: true
Specimen Num: 1
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•
•
GXD Expression
GXD Expression
Probe: MGI:5301887
Assay Type: RNA in situ
Annotation Date: 2012-01-19
Strength: Present
Sex: Male
Emaps: EMAPS:1738319
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:5302047
Age: embryonic day 11.5
Image: 1D XY 11.5
Note: Expressed in the genital ridges.
Specimen Label: 1D XY 11.5
Detected: true
Specimen Num: 2
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5301887
Assay Type: RNA in situ
Annotation Date: 2012-01-19
Strength: Absent
Sex: Female
Emaps: EMAPS:1738319
Stage: TS19
Assay Id: MGI:5302047
Age: embryonic day 11.5
Image: 1D XX 11.5
Specimen Label: 1D XX 11.5
Detected: false
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5301887
Assay Type: RNA in situ
Annotation Date: 2012-01-19
Strength: Absent
Sex: Female
Emaps: EMAPS:1796220
Stage: TS20
Assay Id: MGI:5302047
Age: embryonic day 12.5
Image: 1D XX 12.5
Specimen Label: 1D XX 12.5
Detected: false
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5301887
Assay Type: RNA in situ
Annotation Date: 2012-01-19
Strength: Absent
Sex: Female
Emaps: EMAPS:1796221
Stage: TS21
Assay Id: MGI:5302047
Age: embryonic day 13.5
Image: 1D XX 13.5
Specimen Label: 1D XX 13.5
Detected: false
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5302197
Assay Type: Immunohistochemistry
Annotation Date: 2012-01-20
Strength: Absent
Sex: Female
Emaps: EMAPS:1796221
Stage: TS21
Assay Id: MGI:5302231
Age: embryonic day 13.5
Image: 4D
Specimen Label: 4D
Detected: false
Specimen Num: 2
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•
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•
Publication
12771146 | J:230354
First Author: Kruljac-Letunic A
Year: 2003
Journal: J Biol Chem
Title: The tyrosine kinase Pyk2 regulates Arf1 activity by phosphorylation and inhibition of the Arf-GTPase-activating protein ASAP1.
Volume: 278
Issue: 32
Pages: 29560-70
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Publication
21640103 | J:174314
First Author: Shen CJ
Year: 2011
Journal: Exp Cell Res
Title: Decreased cell adhesion promotes angiogenesis in a Pyk2-dependent manner.
Volume: 317
Issue: 13
Pages: 1860-71
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Publication
31330317 | J:293294
First Author: Gao C
Year: 2019
Journal: Cell Mol Gastroenterol Hepatol
Title: PYK2 Is Involved in Premalignant Acinar Cell Reprogramming and Pancreatic Ductal Adenocarcinoma Maintenance by Phosphorylating β-CateninY654.
Volume: 8
Issue: 4
Pages: 561-578
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Publication
22544749 | J:186506
First Author: Xu J
Year: 2012
Journal: J Biol Chem
Title: Striatal-enriched protein-tyrosine phosphatase (STEP) regulates Pyk2 kinase activity.
Volume: 287
Issue: 25
Pages: 20942-56
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Publication
32313025 | J:289605
First Author: de Pins B
Year: 2020
Journal: Sci Rep
Title: The non-receptor tyrosine kinase Pyk2 modulates acute locomotor effects of cocaine in D1 receptor-expressing neurons of the nucleus accumbens.
Volume: 10
Issue: 1
Pages: 6619
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Publication
20727793 | J:163910
First Author: Davidson D
Year: 2010
Journal: Immunity
Title: The phosphatase PTP-PEST promotes secondary T cell responses by dephosphorylating the protein tyrosine kinase Pyk2.
Volume: 33
Issue: 2
Pages: 167-80
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Publication
28555636 | J:250330
 
First Author: Giralt A
Year: 2017
Journal: Nat Commun
Title: Pyk2 modulates hippocampal excitatory synapses and contributes to cognitive deficits in a Huntington's disease model.
Volume: 8
Pages: 15592
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Publication
34943950 | J:317739
 
First Author: Gourley SL
Year: 2021
Journal: Cells
Title: Pyk2 Stabilizes Striatal Medium Spiny Neuron Structure and Striatal-Dependent Action.
Volume: 10
Issue: 12
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Publication
27226326 | J:240205
First Author: Alvau A
Year: 2016
Journal: Development
Title: The tyrosine kinase FER is responsible for the capacitation-associated increase in tyrosine phosphorylation in murine sperm.
Volume: 143
Issue: 13
Pages: 2325-33
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Publication
30872746 | J:276607
First Author: Thomas KS
Year: 2019
Journal: Sci Rep
Title: Non-redundant functions of FAK and Pyk2 in intestinal epithelial repair.
Volume: 9
Issue: 1
Pages: 4497
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Publication
25659487 | J:220743
First Author: Fukai K
Year: 2015
Journal: Am J Physiol Heart Circ Physiol
Title: Pyk2 aggravates hypoxia-induced pulmonary hypertension by activating HIF-1α.
Volume: 308
Issue: 8
Pages: H951-9
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Publication
9988732 | J:53091
First Author: Lakkakorpi PT
Year: 1999
Journal: J Biol Chem
Title: Stable association of PYK2 and p130(Cas) in osteoclasts and their co-localization in the sealing zone.
Volume: 274
Issue: 8
Pages: 4900-7
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Publication
12578912 | J:81963
First Author: Wang Q
Year: 2003
Journal: J Cell Biol
Title: Regulation of the formation of osteoclastic actin rings by proline-rich tyrosine kinase 2 interacting with gelsolin.
Volume: 160
Issue: 4
Pages: 565-75
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Publication
16546139 | J:107563
First Author: Guignandon A
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Cyclic strain promotes shuttling of PYK2/Hic-5 complex from focal contacts in osteoblast-like cells.
Volume: 343
Issue: 2
Pages: 407-14
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Publication
17684059 | J:128374
First Author: Faure C
Year: 2007
Journal: J Cell Sci
Title: Calcineurin is essential for depolarization-induced nuclear translocation and tyrosine phosphorylation of PYK2 in neurons.
Volume: 120
Issue: Pt 17
Pages: 3034-44
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Publication
23401167 | J:195144
First Author: McGinnis LK
Year: 2013
Journal: Mol Reprod Dev
Title: Protein tyrosine kinase signaling in the mouse oocyte cortex during sperm-egg interactions and anaphase resumption.
Volume: 80
Issue: 4
Pages: 260-72
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Publication
25349423 | J:216771
First Author: Kinoshita Y
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Role for NUP62 depletion and PYK2 redistribution in dendritic retraction resulting from chronic stress.
Volume: 111
Issue: 45
Pages: 16130-5
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Publication
11238453 | J:67886
First Author: Ren XR
Year: 2001
Journal: J Cell Biol
Title: Regulation of CDC42 GTPase by proline-rich tyrosine kinase 2 interacting with PSGAP, a novel pleckstrin homology and Src homology 3 domain containing rhoGAP protein.
Volume: 152
Issue: 5
Pages: 971-84
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Publication
26642240 | J:231935
First Author: Jabara HH
Year: 2016
Journal: Nat Genet
Title: A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency.
Volume: 48
Issue: 1
Pages: 74-8
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Publication
22941736 | J:190159
First Author: Ray BJ
Year: 2012
Journal: J Leukoc Biol
Title: Regulation of osteoclast structure and function by FAK family kinases.
Volume: 92
Issue: 5
Pages: 1021-8
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Publication
23589331 | J:204493
First Author: Rhee I
Year: 2013
Journal: Mol Cell Biol
Title: Macrophage fusion is controlled by the cytoplasmic protein tyrosine phosphatase PTP-PEST/PTPN12.
Volume: 33
Issue: 12
Pages: 2458-69
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Publication
20805505 | J:164360
First Author: Beinke S
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Proline-rich tyrosine kinase-2 is critical for CD8 T-cell short-lived effector fate.
Volume: 107
Issue: 37
Pages: 16234-9
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Publication
29803828 | J:269675
 
First Author: Giralt A
Year: 2018
Journal: Exp Neurol
Title: PTK2B/Pyk2 overexpression improves a mouse model of Alzheimer's disease.
Volume: 307
Pages: 62-73
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30626696 | J:273600
First Author: Lee S
Year: 2019
Journal: J Neurosci
Title: Pyk2 Signaling through Graf1 and RhoA GTPase Is Required for Amyloid-β Oligomer-Triggered Synapse Loss.
Volume: 39
Issue: 10
Pages: 1910-1929
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21372295 | J:191484
First Author: Katsume A
Year: 2011
Journal: Arterioscler Thromb Vasc Biol
Title: Early inflammatory reactions in atherosclerosis are induced by proline-rich tyrosine kinase/reactive oxygen species-mediated release of tumor necrosis factor-alpha and subsequent activation of the p21Cip1/Ets-1/p300 system.
Volume: 31
Issue: 5
Pages: 1084-92
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18483407 | J:151384
First Author: Fisslthaler B
Year: 2008
Journal: Circ Res
Title: Inhibition of endothelial nitric oxide synthase activity by proline-rich tyrosine kinase 2 in response to fluid shear stress and insulin.
Volume: 102
Issue: 12
Pages: 1520-8
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Publication
27796369 | J:259915
 
First Author: Chung IC
Year: 2016
Journal: Sci Rep
Title: Pyk2 activates the NLRP3 inflammasome by directly phosphorylating ASC and contributes to inflammasome-dependent peritonitis.
Volume: 6
Pages: 36214
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12674328 | J:180487
First Author: Gupta A
Year: 2003
Journal: J Bone Miner Res
Title: Leupaxin is a critical adaptor protein in the adhesion zone of the osteoclast.
Volume: 18
Issue: 4
Pages: 669-85
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14739300 | J:89495
First Author: Miyazaki T
Year: 2004
Journal: J Biol Chem
Title: Src kinase activity is essential for osteoclast function.
Volume: 279
Issue: 17
Pages: 17660-6
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19880522 | J:159965
First Author: Lim ST
Year: 2010
Journal: J Biol Chem
Title: Pyk2 inhibition of p53 as an adaptive and intrinsic mechanism facilitating cell proliferation and survival.
Volume: 285
Issue: 3
Pages: 1743-53
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15786712 | J:180575
First Author: Watanabe N
Year: 2005
Journal: Mol Cell Biochem
Title: Leupaxin binds to PEST domain tyrosine phosphatase PEP.
Volume: 269
Issue: 1-2
Pages: 13-7
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Publication
16391003 | J:104401
First Author: Braren R
Year: 2006
Journal: J Cell Biol
Title: Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation.
Volume: 172
Issue: 1
Pages: 151-62
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Publication
28385807 | J:243304
First Author: Soni D
Year: 2017
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Pyk2 phosphorylation of VE-PTP downstream of STIM1-induced Ca2+ entry regulates disassembly of adherens junctions.
Volume: 312
Issue: 6
Pages: L1003-L1017
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Publication
21187437 | J:168915
First Author: Kamen LA
Year: 2011
Journal: J Immunol
Title: Pyk2 is required for neutrophil degranulation and host defense responses to bacterial infection.
Volume: 186
Issue: 3
Pages: 1656-65
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Publication
25967238 | J:226138
First Author: Canobbio I
Year: 2015
Journal: Biochem J
Title: The focal adhesion kinase Pyk2 links Ca2+ signalling to Src family kinase activation and protein tyrosine phosphorylation in thrombin-stimulated platelets.
Volume: 469
Issue: 2
Pages: 199-210
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Publication
22106345 | J:181791
First Author: Consonni A
Year: 2012
Journal: Blood
Title: Role and regulation of phosphatidylinositol 3-kinase β in platelet integrin α2β1 signaling.
Volume: 119
Issue: 3
Pages: 847-56
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25960397 | J:230524
First Author: Manganaro D
Year: 2015
Journal: Biochim Biophys Acta
Title: Activation of phosphatidylinositol 3-kinase β by the platelet collagen receptors integrin α2β1 and GPVI: The role of Pyk2 and c-Cbl.
Volume: 1853
Issue: 8
Pages: 1879-88
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Publication
18542050 | J:137676
First Author: Yamamoto S
Year: 2008
Journal: Nat Med
Title: TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration.
Volume: 14
Issue: 7
Pages: 738-47
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Publication
11274221 | J:79952
First Author: Andreev J
Year: 2001
Journal: J Biol Chem
Title: Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade.
Volume: 276
Issue: 23
Pages: 20130-5
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Publication
19416922 | J:248211
First Author: Marqués M
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Specific function of phosphoinositide 3-kinase beta in the control of DNA replication.
Volume: 106
Issue: 18
Pages: 7525-30
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14500722 | J:86728
First Author: Moissoglu K
Year: 2003
Journal: J Biol Chem
Title: v-Src rescues actin-based cytoskeletal architecture and cell motility and induces enhanced anchorage independence during oncogenic transformation of focal adhesion kinase-null fibroblasts.
Volume: 278
Issue: 48
Pages: 47946-59
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Publication
15761030 | J:99228
First Author: Sekimoto H
Year: 2005
Journal: Mol Endocrinol
Title: (alpha)v(beta)3 integrins and Pyk2 mediate insulin-like growth factor I activation of Src and mitogen-activated protein kinase in 3T3-L1 cells.
Volume: 19
Issue: 7
Pages: 1859-67
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Publication
17581824 | J:124773
First Author: Plotkin LI
Year: 2007
Journal: J Biol Chem
Title: Glucocorticoids induce osteocyte apoptosis by blocking focal adhesion kinase-mediated survival. Evidence for inside-out signaling leading to anoikis.
Volume: 282
Issue: 33
Pages: 24120-30
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Publication
19380485 | J:149899
First Author: Bruzzaniti A
Year: 2009
Journal: Mol Cell Biol
Title: Dynamin reduces Pyk2 Y402 phosphorylation and SRC binding in osteoclasts.
Volume: 29
Issue: 13
Pages: 3644-56
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Publication
19435801 | J:150586
First Author: Tomar A
Year: 2009
Journal: J Cell Sci
Title: A FAK-p120RasGAP-p190RhoGAP complex regulates polarity in migrating cells.
Volume: 122
Issue: Pt 11
Pages: 1852-62
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19841181 | J:157191
First Author: Pierau M
Year: 2009
Journal: J Immunol
Title: Protein kinase B/Akt signals impair Th17 differentiation and support natural regulatory T cell function and induced regulatory T cell formation.
Volume: 183
Issue: 10
Pages: 6124-34
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23711511 | J:202540
First Author: Martel-Gallegos G
Year: 2013
Journal: Biochim Biophys Acta
Title: Oxidative stress induced by P2X7 receptor stimulation in murine macrophages is mediated by c-Src/Pyk2 and ERK1/2.
Volume: 1830
Issue: 10
Pages: 4650-9
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Publication
32693110 | J:299443
First Author: Canino J
Year: 2020
Journal: Biochim Biophys Acta Mol Cell Res
Title: The proline-rich tyrosine kinase Pyk2 modulates integrin-mediated neutrophil adhesion and reactive oxygen species generation.
Volume: 1867
Issue: 10
Pages: 118799
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7499242 | J:29773
First Author: Avraham S
Year: 1995
Journal: J Biol Chem
Title: Identification and characterization of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain.
Volume: 270
Issue: 46
Pages: 27742-51
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9211912 | J:41724
First Author: Malgaretti N
Year: 1997
Journal: J Biol Chem
Title: Mmot1, a new helix-loop-helix transcription factor gene displaying a sharp expression boundary in the embryonic mouse brain.
Volume: 272
Issue: 28
Pages: 17632-9
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22984613 | J:191757
First Author: Balasubramanian S
Year: 2012
Journal: PLoS One
Title: β3 integrin in cardiac fibroblast is critical for extracellular matrix accumulation during pressure overload hypertrophy in mouse.
Volume: 7
Issue: 9
Pages: e45076
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Publication
29911975 | J:264145
   
First Author: Fan L
Year: 2018
Journal: Elife
Title: Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.
Volume: 7
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17460065 | J:121087
First Author: Bjarnadottir M
Year: 2007
Journal: J Neurosci
Title: Neuregulin1 (NRG1) signaling through Fyn modulates NMDA receptor phosphorylation: differential synaptic function in NRG1+/- knock-outs compared with wild-type mice.
Volume: 27
Issue: 17
Pages: 4519-29
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34480901 | J:310638
First Author: Nies SH
Year: 2021
Journal: J Biol Chem
Title: Spreading of Alzheimer tau seeds is enhanced by aging and template matching with limited impact of amyloid-β.
Volume: 297
Issue: 4
Pages: 101159
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29436516 | J:273748
First Author: Iskander SM
Year: 2018
Journal: J Am Soc Nephrol
Title: Protein Kinase 2β Is Expressed in Neural Crest-Derived Urinary Pacemaker Cells and Required for Pyeloureteric Contraction.
Volume: 29
Issue: 4
Pages: 1198-1209
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Publication
34529077 | J:326577
First Author: Zheng J
Year: 2022
Journal: J Mol Cell Biol
Title: Pyk2 suppresses contextual fear memory in an autophosphorylation-independent manner.
Volume: 13
Issue: 11
Pages: 808-821
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23216754 | J:195447
First Author: Cipolla L
Year: 2013
Journal: J Thromb Haemost
Title: The proline-rich tyrosine kinase Pyk2 regulates platelet integrin αIIbβ3 outside-in signaling.
Volume: 11
Issue: 2
Pages: 345-56
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23936270 | J:204448
First Author: St-Pierre J
Year: 2013
Journal: PLoS One
Title: A role for the protein tyrosine phosphatase CD45 in macrophage adhesion through the regulation of paxillin degradation.
Volume: 8
Issue: 7
Pages: e71531
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24841674 | J:216329
First Author: Hum JM
Year: 2014
Journal: PLoS One
Title: Mechanical loading in osteocytes induces formation of a Src/Pyk2/MBD2 complex that suppresses anabolic gene expression.
Volume: 9
Issue: 5
Pages: e97942
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16899073 | J:112589
First Author: Le HT
Year: 2006
Journal: J Neurochem
Title: Reduced NMDA receptor tyrosine phosphorylation in PTPalpha-deficient mouse synaptosomes is accompanied by inhibition of four src family kinases and Pyk2: an upstream role for PTPalpha in NMDA receptor regulation.
Volume: 98
Issue: 6
Pages: 1798-809
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20442405 | J:165360
First Author: Lim ST
Year: 2010
Journal: J Biol Chem
Title: Knock-in mutation reveals an essential role for focal adhesion kinase activity in blood vessel morphogenesis and cell motility-polarity but not cell proliferation.
Volume: 285
Issue: 28
Pages: 21526-36
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Publication
18206965 | J:180459
First Author: Lim ST
Year: 2008
Journal: Mol Cell
Title: Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation.
Volume: 29
Issue: 1
Pages: 9-22
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