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Search results 101 to 200 out of 738 for Snca

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Type Details Score
Publication
14572463 | J:86222
First Author: Gispert S
Year: 2003
Journal: Mol Cell Neurosci
Title: Transgenic mice expressing mutant A53T human alpha-synuclein show neuronal dysfunction in the absence of aggregate formation.
Volume: 24
Issue: 2
Pages: 419-29
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Publication
17708336 | J:125212
First Author: Michell AW
Year: 2007
Journal: Cell Transplant
Title: The effect of truncated human alpha-synuclein (1-120) on dopaminergic cells in a transgenic mouse model of Parkinson's disease.
Volume: 16
Issue: 5
Pages: 461-74
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Publication
16611810 | J:108310
First Author: Tofaris GK
Year: 2006
Journal: J Neurosci
Title: Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120): implications for Lewy body disorders.
Volume: 26
Issue: 15
Pages: 3942-50
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Publication
32943057 | J:313553
First Author: Li N
Year: 2020
Journal: J Neuroinflammation
Title: Immunoregulation of microglial polarization: an unrecognized physiological function of α-synuclein.
Volume: 17
Issue: 1
Pages: 272
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Publication
21296890 | J:170923
First Author: Desplats P
Year: 2011
Journal: J Biol Chem
Title: Alpha-synuclein sequesters Dnmt1 from the nucleus: a novel mechanism for epigenetic alterations in Lewy body diseases.
Volume: 286
Issue: 11
Pages: 9031-7
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Publication
33009395 | J:303355
First Author: Roberts BM
Year: 2020
Journal: Nat Commun
Title: GABA uptake transporters support dopamine release in dorsal striatum with maladaptive downregulation in a parkinsonism model.
Volume: 11
Issue: 1
Pages: 4958
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Publication
24325796 | J:212732
First Author: Martin LJ
Year: 2014
Journal: Neurobiol Aging
Title: Mitochondrial permeability transition pore regulates Parkinson's disease development in mutant α-synuclein transgenic mice.
Volume: 35
Issue: 5
Pages: 1132-52
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Publication
24239384 | J:212739
First Author: Rothman SM
Year: 2014
Journal: Neurobiol Aging
Title: Metabolic abnormalities and hypoleptinemia in α-synuclein A53T mutant mice.
Volume: 35
Issue: 5
Pages: 1153-61
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Publication
25855184 | J:221680
First Author: Kett LR
Year: 2015
Journal: J Neurosci
Title: α-Synuclein-independent histopathological and motor deficits in mice lacking the endolysosomal Parkinsonism protein Atp13a2.
Volume: 35
Issue: 14
Pages: 5724-42
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Publication
21272100 | J:174647
First Author: Prasad K
Year: 2011
Journal: Eur J Neurosci
Title: Biochemical and morphological consequences of human α-synuclein expression in a mouse α-synuclein null background.
Volume: 33
Issue: 4
Pages: 642-56
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Publication
28362802 | J:242306
First Author: Kline RA
Year: 2017
Journal: PLoS Genet
Title: Comparison of independent screens on differentially vulnerable motor neurons reveals alpha-synuclein as a common modifier in motor neuron diseases.
Volume: 13
Issue: 3
Pages: e1006680
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Publication
20798282 | J:164218
First Author: Burré J
Year: 2010
Journal: Science
Title: Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro.
Volume: 329
Issue: 5999
Pages: 1663-7
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Publication
18297066 | J:131733
First Author: Gallardo G
Year: 2008
Journal: Nat Neurosci
Title: A molecular pathway of neurodegeneration linking alpha-synuclein to ApoE and Abeta peptides.
Volume: 11
Issue: 3
Pages: 301-8
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Publication
28052246 | J:251123
First Author: Vargas KJ
Year: 2017
Journal: Cell Rep
Title: Synucleins Have Multiple Effects on Presynaptic Architecture.
Volume: 18
Issue: 1
Pages: 161-173
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Publication
31509576 | J:279439
First Author: Rahimi-Balaei M
Year: 2019
Journal: PLoS One
Title: Loss of prostatic acid phosphatase and α-synuclein cause motor circuit degeneration without altering cerebellar patterning.
Volume: 14
Issue: 9
Pages: e0222234
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Publication
28614796 | J:344231
 
First Author: Chandra R
Year: 2017
Journal: JCI Insight
Title: α-Synuclein in gut endocrine cells and its implications for Parkinson's disease.
Volume: 2
Issue: 12
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Publication
30983487 | J:297708
First Author: Ho PW
Year: 2020
Journal: Autophagy
Title: Age-dependent accumulation of oligomeric SNCA/α-synuclein from impaired degradation in mutant LRRK2 knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA).
Volume: 16
Issue: 2
Pages: 347-370
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Publication
29310663 | J:264998
First Author: Yun SP
Year: 2018
Journal: Mol Neurodegener
Title: α-Synuclein accumulation and GBA deficiency due to L444P GBA mutation contributes to MPTP-induced parkinsonism.
Volume: 13
Issue: 1
Pages: 1
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Publication
34220415 | J:314280
 
First Author: Martinez Hernandez A
Year: 2021
Journal: Front Neurosci
Title: Low-Expressing Synucleinopathy Mouse Models Based on Oligomer-Forming Mutations and C-Terminal Truncation of α-Synuclein.
Volume: 15
Pages: 643391
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Publication
31109379 | J:339104
First Author: Krejciova Z
Year: 2019
Journal: Acta Neuropathol Commun
Title: Replication of multiple system atrophy prions in primary astrocyte cultures from transgenic mice expressing human α-synuclein.
Volume: 7
Issue: 1
Pages: 81
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Publication
31644913 | J:286926
First Author: Hunn BHM
Year: 2019
Journal: Cell Rep
Title: Impairment of Macroautophagy in Dopamine Neurons Has Opposing Effects on Parkinsonian Pathology and Behavior.
Volume: 29
Issue: 4
Pages: 920-931.e7
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Publication
23342162 | J:195852
First Author: Xie Q
Year: 2013
Journal: PLoS One
Title: Pax6 interactions with chromatin and identification of its novel direct target genes in lens and forebrain.
Volume: 8
Issue: 1
Pages: e54507
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Publication
38063197 | J:344232
 
First Author: Chandra R
Year: 2023
Journal: JCI Insight
Title: Gut mucosal cells transfer α-synuclein to the vagus nerve.
Volume: 8
Issue: 23
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Publication
16269331 | J:115193
First Author: Chandra S
Year: 2005
Journal: Cell
Title: Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration.
Volume: 123
Issue: 3
Pages: 383-96
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Publication
20064389 | J:156512
First Author: Lin X
Year: 2009
Journal: Neuron
Title: Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein.
Volume: 64
Issue: 6
Pages: 807-27
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Protein Coding Gene
MGP_CAROLIEiJ_G0028452 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0030823 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0030790 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0030718 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0030802 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0030516 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1277151 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0031260 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0029914 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0030489 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0030640 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0030593 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0030725 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0030628 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0031286 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0029629 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0029996 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0022193 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0029457 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
9601701 | J:49927
First Author: Hong L
Year: 1998
Journal: Neuroreport
Title: The cDNA cloning and ontogeny of mouse alpha-synuclein.
Volume: 9
Issue: 6
Pages: 1239-43
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Publication
25246573 | J:216463
First Author: Burré J
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: α-Synuclein assembles into higher-order multimers upon membrane binding to promote SNARE complex formation.
Volume: 111
Issue: 40
Pages: E4274-83
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Publication
20524960 | J:163482
First Author: Siebert H
Year: 2010
Journal: J Neurochem
Title: Over-expression of alpha-synuclein in the nervous system enhances axonal degeneration after peripheral nerve lesion in a transgenic mouse strain.
Volume: 114
Issue: 4
Pages: 1007-18
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Publication
27466341 | J:234626
First Author: Spencer B
Year: 2016
Journal: J Neurosci
Title: Reducing Endogenous α-Synuclein Mitigates the Degeneration of Selective Neuronal Populations in an Alzheimer's Disease Transgenic Mouse Model.
Volume: 36
Issue: 30
Pages: 7971-84
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Publication
23643841 | J:197984
 
First Author: Hansen C
Year: 2013
Journal: Neurobiol Dis
Title: A novel α-synuclein-GFP mouse model displays progressive motor impairment, olfactory dysfunction and accumulation of α-synuclein-GFP.
Volume: 56
Pages: 145-55
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Publication
30308173 | J:268903
First Author: Nuber S
Year: 2018
Journal: Neuron
Title: Abrogating Native α-Synuclein Tetramers in Mice Causes a L-DOPA-Responsive Motor Syndrome Closely Resembling Parkinson's Disease.
Volume: 100
Issue: 1
Pages: 75-90.e5
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Publication
32996158 | J:301897
First Author: Nuber S
Year: 2021
Journal: Ann Neurol
Title: A Stearoyl-Coenzyme A Desaturase Inhibitor Prevents Multiple Parkinson Disease Phenotypes in α-Synuclein Mice.
Volume: 89
Issue: 1
Pages: 74-90
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Publication
34233191 | J:328722
First Author: Fonseca-Ornelas L
Year: 2021
Journal: Cell Rep
Title: Altered conformation of α-synuclein drives dysfunction of synaptic vesicles in a synaptosomal model of Parkinson's disease.
Volume: 36
Issue: 1
Pages: 109333
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Publication
30249789 | J:267419
First Author: Teravskis PJ
Year: 2018
Journal: J Neurosci
Title: A53T Mutant Alpha-Synuclein Induces Tau-Dependent Postsynaptic Impairment Independently of Neurodegenerative Changes.
Volume: 38
Issue: 45
Pages: 9754-9767
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Publication
21734300 | J:174555
First Author: Lim Y
Year: 2011
Journal: J Neurosci
Title: α-Syn suppression reverses synaptic and memory defects in a mouse model of dementia with Lewy bodies.
Volume: 31
Issue: 27
Pages: 10076-87
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Publication
22537068 | J:186510
First Author: Xie W
Year: 2012
Journal: J Neurochem
Title: Alpha-synuclein impairs normal dynamics of mitochondria in cell and animal models of Parkinson's disease.
Volume: 122
Issue: 2
Pages: 404-14
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Publication
20152114 | J:167658
First Author: Nemani VM
Year: 2010
Journal: Neuron
Title: Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis.
Volume: 65
Issue: 1
Pages: 66-79
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Publication
19228951 | J:146833
First Author: Lu XH
Year: 2009
Journal: J Neurosci
Title: Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant alpha-synuclein.
Volume: 29
Issue: 7
Pages: 1962-76
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Publication
12009758 | J:76482
First Author: Richfield EK
Year: 2002
Journal: Exp Neurol
Title: Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice.
Volume: 175
Issue: 1
Pages: 35-48
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Publication
10678833 | J:60638
First Author: Masliah E
Year: 2000
Journal: Science
Title: Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders.
Volume: 287
Issue: 5456
Pages: 1265-9
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Publication
20071342 | J:161080
First Author: Lee HJ
Year: 2010
Journal: J Biol Chem
Title: Direct transfer of alpha-synuclein from neuron to astroglia causes inflammatory responses in synucleinopathies.
Volume: 285
Issue: 12
Pages: 9262-72
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Publication
21091473 | J:170263
First Author: Steidinger TU
Year: 2011
Journal: J Neurochem
Title: A neuroprotective role for angiogenin in models of Parkinson's disease.
Volume: 116
Issue: 3
Pages: 334-41
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Publication
21559417 | J:172452
First Author: Masliah E
Year: 2011
Journal: PLoS One
Title: Passive immunization reduces behavioral and neuropathological deficits in an alpha-synuclein transgenic model of Lewy body disease.
Volume: 6
Issue: 4
Pages: e19338
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Publication
28351932 | J:263591
First Author: Blumenstock S
Year: 2017
Journal: EMBO Mol Med
Title: Seeding and transgenic overexpression of alpha-synuclein triggers dendritic spine pathology in the neocortex.
Volume: 9
Issue: 5
Pages: 716-731
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Publication
19627450 | J:153557
First Author: Rappley I
Year: 2009
Journal: J Neurochem
Title: Lipidomic profiling in mouse brain reveals differences between ages and genders, with smaller changes associated with alpha-synuclein genotype.
Volume: 111
Issue: 1
Pages: 15-25
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Publication
12062037 | J:76657
First Author: Giasson BI
Year: 2002
Journal: Neuron
Title: Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein.
Volume: 34
Issue: 4
Pages: 521-33
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Publication
18650345 | J:138194
First Author: Gao HM
Year: 2008
Journal: J Neurosci
Title: Neuroinflammation and oxidation/nitration of alpha-synuclein linked to dopaminergic neurodegeneration.
Volume: 28
Issue: 30
Pages: 7687-98
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Publication
29976670 | J:277499
 
First Author: Ayers JI
Year: 2018
Journal: J Virol
Title: Localized Induction of Wild-Type and Mutant Alpha-Synuclein Aggregation Reveals Propagation along Neuroanatomical Tracts.
Volume: 92
Issue: 18
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Publication
25002524 | J:212256
First Author: Sacino AN
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice.
Volume: 111
Issue: 29
Pages: 10732-7
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Publication
28910367 | J:249959
First Author: Dhillon JS
Year: 2017
Journal: PLoS One
Title: A novel panel of α-synuclein antibodies reveal distinctive staining profiles in synucleinopathies.
Volume: 12
Issue: 9
Pages: e0184731
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Publication
25209277 | J:310696
First Author: Sacino AN
Year: 2014
Journal: J Neurosci
Title: Brain injection of α-synuclein induces multiple proteinopathies, gliosis, and a neuronal injury marker.
Volume: 34
Issue: 37
Pages: 12368-78
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Publication
30116778 | J:287434
First Author: Sumitomo A
Year: 2018
Journal: Sci Adv
Title: A mouse model of 22q11.2 deletions: Molecular and behavioral signatures of Parkinson's disease and schizophrenia.
Volume: 4
Issue: 8
Pages: eaar6637
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Publication
30599154 | J:285200
 
First Author: Minakaki G
Year: 2019
Journal: Behav Brain Res
Title: Treadmill exercise intervention improves gait and postural control in alpha-synuclein mouse models without inducing cerebral autophagy.
Volume: 363
Pages: 199-215
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Publication
16872721 | J:128051
First Author: Freichel C
Year: 2007
Journal: Neurobiol Aging
Title: Age-dependent cognitive decline and amygdala pathology in alpha-synuclein transgenic mice.
Volume: 28
Issue: 9
Pages: 1421-35
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Publication
12438441 | J:80181
First Author: Neumann M
Year: 2002
Journal: J Clin Invest
Title: Misfolded proteinase K-resistant hyperphosphorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucleinopathies.
Volume: 110
Issue: 10
Pages: 1429-39
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Publication
19272424 | J:149844
First Author: Schell H
Year: 2009
Journal: Neuroscience
Title: Nuclear and neuritic distribution of serine-129 phosphorylated alpha-synuclein in transgenic mice.
Volume: 160
Issue: 4
Pages: 796-804
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Publication
30092270 | J:268718
 
First Author: Paiva I
Year: 2018
Journal: Neurobiol Dis
Title: Alpha-synuclein deregulates the expression of COL4A2 and impairs ER-Golgi function.
Volume: 119
Pages: 121-135
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Publication
11733371 | J:100981
First Author: Kahle PJ
Year: 2001
Journal: Am J Pathol
Title: Selective insolubility of alpha-synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model.
Volume: 159
Issue: 6
Pages: 2215-25
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Publication
11359883 | J:69529
First Author: Rathke-Hartlieb S
Year: 2001
Journal: J Neurochem
Title: Sensitivity to MPTP is not increased in Parkinson's disease-associated mutant alpha-synuclein transgenic mice.
Volume: 77
Issue: 4
Pages: 1181-4
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Publication
25961568 | J:235336
First Author: Schreglmann SR
Year: 2015
Journal: PLoS One
Title: The temporal expression pattern of alpha-synuclein modulates olfactory neurogenesis in transgenic mice.
Volume: 10
Issue: 5
Pages: e0126261
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Publication
23667637 | J:202180
First Author: Sarafian TA
Year: 2013
Journal: PLoS One
Title: Impairment of mitochondria in adult mouse brain overexpressing predominantly full-length, N-terminally acetylated human α-synuclein.
Volume: 8
Issue: 5
Pages: e63557
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Publication
22815513 | J:186464
First Author: Reznichenko L
Year: 2012
Journal: J Neurosci
Title: In vivo alterations in calcium buffering capacity in transgenic mouse model of synucleinopathy.
Volume: 32
Issue: 29
Pages: 9992-8
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Publication
30509990 | J:269264
First Author: Yan R
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Synergistic neuroprotection by coffee components eicosanoyl-5-hydroxytryptamide and caffeine in models of Parkinson's disease and DLB.
Volume: 115
Issue: 51
Pages: E12053-E12062
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Publication
28117497 | J:268174
First Author: Sarafian TA
Year: 2017
Journal: J Neurosci Res
Title: Stimulation of synaptoneurosome glutamate release by monomeric and fibrillated α-synuclein.
Volume: 95
Issue: 9
Pages: 1871-1887
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Publication
22045698 | J:179713
First Author: Tomás-Zapico C
Year: 2012
Journal: Hum Mol Genet
Title: α-Synuclein accumulates in huntingtin inclusions but forms independent filaments and its deficiency attenuates early phenotype in a mouse model of Huntington's disease.
Volume: 21
Issue: 3
Pages: 495-510
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Publication
15797547 | J:99814
First Author: Yazawa I
Year: 2005
Journal: Neuron
Title: Mouse model of multiple system atrophy alpha-synuclein expression in oligodendrocytes causes glial and neuronal degeneration.
Volume: 45
Issue: 6
Pages: 847-59
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Publication
29743672 | J:262416
First Author: Peng C
Year: 2018
Journal: Nature
Title: Cellular milieu imparts distinct pathological α-synuclein strains in α-synucleinopathies.
Volume: 557
Issue: 7706
Pages: 558-563
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Publication
15684072 | J:96471
First Author: Li W
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations.
Volume: 102
Issue: 6
Pages: 2162-7
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Publication
15840579 | J:100267
First Author: Liu CW
Year: 2005
Journal: J Biol Chem
Title: A precipitating role for truncated alpha-synuclein and the proteasome in alpha-synuclein aggregation: implications for pathogenesis of Parkinson disease.
Volume: 280
Issue: 24
Pages: 22670-8
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Publication
35250825 | J:321950
 
First Author: Liu W
Year: 2022
Journal: Front Neurol
Title: Characterization of a Novel Monoclonal Antibody for Serine-129 Phosphorylated α-Synuclein: A Potential Application for Clinical and Basic Research.
Volume: 13
Pages: 821792
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Publication
16291942 | J:102867
First Author: Shults CW
Year: 2005
Journal: J Neurosci
Title: Neurological and neurodegenerative alterations in a transgenic mouse model expressing human alpha-synuclein under oligodendrocyte promoter: implications for multiple system atrophy.
Volume: 25
Issue: 46
Pages: 10689-99
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Publication
15765523 | J:238692
First Author: Rockenstein E
Year: 2005
Journal: J Neurosci Res
Title: Lysosomal pathology associated with alpha-synuclein accumulation in transgenic models using an eGFP fusion protein.
Volume: 80
Issue: 2
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