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Search results 101 to 200 out of 2283 for Mapt

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Type Details Score
Publication
21098287 | J:167148
First Author: Kickstein E
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Biguanide metformin acts on tau phosphorylation via mTOR/protein phosphatase 2A (PP2A) signaling.
Volume: 107
Issue: 50
Pages: 21830-5
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Publication
22892311 | J:194513
First Author: Xiong Y
Year: 2013
Journal: Neurobiol Aging
Title: Zinc induces protein phosphatase 2A inactivation and tau hyperphosphorylation through Src dependent PP2A (tyrosine 307) phosphorylation.
Volume: 34
Issue: 3
Pages: 745-56
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Publication
35045281 | J:327028
First Author: Qureshi YH
Year: 2022
Journal: Cell Rep
Title: The neuronal retromer can regulate both neuronal and microglial phenotypes of Alzheimer's disease.
Volume: 38
Issue: 3
Pages: 110262
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Publication
32039516 | J:292621
First Author: Zhu K
Year: 2020
Journal: Glia
Title: Absence of microglia or presence of peripherally-derived macrophages does not affect tau pathology in young or old hTau mice.
Volume: 68
Issue: 7
Pages: 1466-1478
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Publication
30253780 | J:267673
First Author: Bemiller SM
Year: 2018
Journal: J Neuroinflammation
Title: Genetically enhancing the expression of chemokine domain of CX3CL1 fails to prevent tau pathology in mouse models of tauopathy.
Volume: 15
Issue: 1
Pages: 278
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Publication
25802082 | J:284340
First Author: Giannopoulos PF
Year: 2015
Journal: Biol Psychiatry
Title: Pharmacologic inhibition of 5-lipoxygenase improves memory, rescues synaptic dysfunction, and ameliorates tau pathology in a transgenic model of tauopathy.
Volume: 78
Issue: 10
Pages: 693-701
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Publication
17304350 | J:120752
First Author: Dickey CA
Year: 2007
Journal: J Clin Invest
Title: The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins.
Volume: 117
Issue: 3
Pages: 648-58
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Publication
29175372 | J:257585
 
First Author: Rossi F
Year: 2018
Journal: Behav Brain Res
Title: NAD-biosynthetic enzyme NMNAT1 reduces early behavioral impairment in the htau mouse model of tauopathy.
Volume: 339
Pages: 140-152
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Publication
32603655 | J:301432
First Author: Roussarie JP
Year: 2020
Journal: Neuron
Title: Selective Neuronal Vulnerability in Alzheimer's Disease: A Network-Based Analysis.
Volume: 107
Issue: 5
Pages: 821-835.e12
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Publication
27070146 | J:253550
First Author: Yetman MJ
Year: 2016
Journal: PLoS One
Title: Humanized Tau Mice with Regionalized Amyloid Exhibit Behavioral Deficits but No Pathological Interaction.
Volume: 11
Issue: 4
Pages: e0153724
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Publication
21573167 | J:172426
First Author: Phillips M
Year: 2011
Journal: PLoS One
Title: Olfactory and visuospatial learning and memory performance in two strains of Alzheimer's disease model mice--a longitudinal study.
Volume: 6
Issue: 5
Pages: e19567
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Publication
37083538 | J:337545
First Author: Zhou LT
Year: 2023
Journal: Sci Adv
Title: Tau pathology epigenetically remodels the neuron-glial cross-talk in Alzheimer's disease.
Volume: 9
Issue: 16
Pages: eabq7105
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Publication
31160584 | J:278451
First Author: Hashimoto S
Year: 2019
Journal: Nat Commun
Title: Tau binding protein CAPON induces tau aggregation and neurodegeneration.
Volume: 10
Issue: 1
Pages: 2394
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Publication
32829029 | J:304391
 
First Author: Race B
Year: 2020
Journal: Neurobiol Dis
Title: Prion-associated cerebral amyloid angiopathy is not exacerbated by human phosphorylated tau aggregates in scrapie-infected mice expressing anchorless prion protein.
Volume: 144
Pages: 105057
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Publication
29037207 | J:285524
First Author: Bemiller SM
Year: 2017
Journal: Mol Neurodegener
Title: TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy.
Volume: 12
Issue: 1
Pages: 74
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Publication
27676333 | J:239562
 
First Author: Rosa E
Year: 2016
Journal: Neurobiol Aging
Title: Tau downregulates BDNF expression in animal and cellular models of Alzheimer's disease.
Volume: 48
Pages: 135-142
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Publication
11135642 | J:66561
First Author: Tucker KL
Year: 2001
Journal: Nat Neurosci
Title: Neurotrophins are required for nerve growth during development.
Volume: 4
Issue: 1
Pages: 29-37
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Publication
30809933 | J:295898
First Author: Xie AJ
Year: 2019
Journal: Aging Cell
Title: Tau overexpression impairs neuronal endocytosis by decreasing the GTPase dynamin 1 through the miR-132/MeCP2 pathway.
Volume: 18
Issue: 3
Pages: e12929
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Publication
17908241 | J:128741
First Author: Kelleher I
Year: 2007
Journal: J Neurochem
Title: Kinase activities increase during the development of tauopathy in htau mice.
Volume: 103
Issue: 6
Pages: 2256-67
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Publication
17517623 | J:259130
First Author: Luo W
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies.
Volume: 104
Issue: 22
Pages: 9511-6
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Publication
25038828 | J:232467
First Author: Fernández-Nogales M
Year: 2014
Journal: Nat Med
Title: Huntington's disease is a four-repeat tauopathy with tau nuclear rods.
Volume: 20
Issue: 8
Pages: 881-5
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Publication
27736877 | J:251663
First Author: van Hummel A
Year: 2016
Journal: PLoS One
Title: No Overt Deficits in Aged Tau-Deficient C57Bl/6.Mapttm1(EGFP)Kit GFP Knockin Mice.
Volume: 11
Issue: 10
Pages: e0163236
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Publication
22194194 | J:181894
First Author: Sapir T
Year: 2012
Journal: Hum Mol Genet
Title: Tau's role in the developing brain: implications for intellectual disability.
Volume: 21
Issue: 8
Pages: 1681-92
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Publication
28922155 | J:312841
First Author: Antón-Fernández A
Year: 2017
Journal: J Alzheimers Dis
Title: Phospho-Tau Accumulation and Structural Alterations of the Golgi Apparatus of Cortical Pyramidal Neurons in the P301S Tauopathy Mouse Model.
Volume: 60
Issue: 2
Pages: 651-661
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Publication
26436904 | J:336203
First Author: Asai H
Year: 2015
Journal: Nat Neurosci
Title: Depletion of microglia and inhibition of exosome synthesis halt tau propagation.
Volume: 18
Issue: 11
Pages: 1584-93
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Publication
21698260 | J:174441
First Author: Takeuchi H
Year: 2011
Journal: PLoS One
Title: P301S mutant human tau transgenic mice manifest early symptoms of human tauopathies with dementia and altered sensorimotor gating.
Volume: 6
Issue: 6
Pages: e21050
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Publication
22984603 | J:192890
First Author: Mewes A
Year: 2012
Journal: PLoS One
Title: Organotypic brain slice cultures of adult transgenic P301S mice--a model for tauopathy studies.
Volume: 7
Issue: 9
Pages: e45017
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Publication
20143409 | J:284568
First Author: Spatara ML
Year: 2010
Journal: J Neurosci Res
Title: Transgenic mouse and cell culture models demonstrate a lack of mechanistic connection between endoplasmic reticulum stress and tau dysfunction.
Volume: 88
Issue: 9
Pages: 1951-61
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Publication
11159192 | J:67379
First Author: Ishihara T
Year: 2001
Journal: Am J Pathol
Title: Age-dependent induction of congophilic neurofibrillary tau inclusions in tau transgenic mice.
Volume: 158
Issue: 2
Pages: 555-62
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Publication
11749044 | J:73872
First Author: Lim F
Year: 2001
Journal: Mol Cell Neurosci
Title: FTDP-17 mutations in tau transgenic mice provoke lysosomal abnormalities and Tau filaments in forebrain.
Volume: 18
Issue: 6
Pages: 702-14
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Publication
17341679 | J:129032
First Author: Sennvik K
Year: 2007
Journal: FASEB J
Title: Tau-4R suppresses proliferation and promotes neuronal differentiation in the hippocampus of tau knockin/knockout mice.
Volume: 21
Issue: 9
Pages: 2149-61
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Publication
36763499 | J:333453
First Author: Moayedi Y
Year: 2023
Journal: Cell Rep
Title: The cellular basis of mechanosensation in mammalian tongue.
Volume: 42
Issue: 2
Pages: 112087
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Publication
27629715 | J:240514
First Author: Sherman MA
Year: 2016
Journal: J Neurosci
Title: Soluble Conformers of Aβ and Tau Alter Selective Proteins Governing Axonal Transport.
Volume: 36
Issue: 37
Pages: 9647-58
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Publication
31085626 | J:276872
 
First Author: Li XG
Year: 2019
Journal: EMBO Rep
Title: Tau accumulation triggers STAT1-dependent memory deficits by suppressing NMDA receptor expression.
Volume: 20
Issue: 6
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Publication
11641718 | J:71413
First Author: Poorkaj P
Year: 2001
Journal: Mamm Genome
Title: A genomic sequence analysis of the mouse and human microtubule-associated protein tau.
Volume: 12
Issue: 9
Pages: 700-12
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Publication
29398363 | J:260627
First Author: McInnes J
Year: 2018
Journal: Neuron
Title: Synaptogyrin-3 Mediates Presynaptic Dysfunction Induced by Tau.
Volume: 97
Issue: 4
Pages: 823-835.e8
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Publication
35858909 | J:326808
First Author: Hausrat TJ
Year: 2022
Journal: Nat Commun
Title: Disruption of tubulin-alpha4a polyglutamylation prevents aggregation of hyper-phosphorylated tau and microglia activation in mice.
Volume: 13
Issue: 1
Pages: 4192
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Publication
31324720 | J:281313
First Author: Schweig JE
Year: 2019
Journal: J Biol Chem
Title: Spleen tyrosine kinase (SYK) blocks autophagic Tau degradation in vitro and in vivo.
Volume: 294
Issue: 36
Pages: 13378-13395
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Publication
22378884 | J:182685
First Author: Na ES
Year: 2012
Journal: J Neurosci
Title: A mouse model for MeCP2 duplication syndrome: MeCP2 overexpression impairs learning and memory and synaptic transmission.
Volume: 32
Issue: 9
Pages: 3109-17
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Publication
20335457 | J:159220
First Author: Sanno H
Year: 2010
Journal: J Neurosci
Title: Control of postnatal apoptosis in the neocortex by RhoA-subfamily GTPases determines neuronal density.
Volume: 30
Issue: 12
Pages: 4221-31
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Publication
29453339 | J:262745
First Author: Biundo F
Year: 2018
Journal: Sci Rep
Title: A role for tau in learning, memory and synaptic plasticity.
Volume: 8
Issue: 1
Pages: 3184
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Publication
35250480 | J:321949
 
First Author: Benderradji H
Year: 2022
Journal: Front Mol Neurosci
Title: Impaired Glucose Homeostasis in a Tau Knock-In Mouse Model.
Volume: 15
Pages: 841892
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Publication
37798679 | J:342503
First Author: Schweighauser M
Year: 2023
Journal: Acta Neuropathol Commun
Title: Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau.
Volume: 11
Issue: 1
Pages: 160
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Publication
30373880 | J:269026
First Author: Wang ZH
Year: 2018
Journal: J Exp Med
Title: Delta-secretase (AEP) mediates tau-splicing imbalance and accelerates cognitive decline in tauopathies.
Volume: 215
Issue: 12
Pages: 3038-3056
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Publication
22687952 | J:207068
 
First Author: Pozueta J
Year: 2013
Journal: Neuroscience
Title: Synaptic changes in Alzheimer's disease and its models.
Volume: 251
Pages: 51-65
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Publication
30322903 | J:269000
First Author: Zhu Y
Year: 2018
Journal: J Neurosci
Title: Chronic Sleep Disruption Advances the Temporal Progression of Tauopathy in P301S Mutant Mice.
Volume: 38
Issue: 48
Pages: 10255-10270
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Publication
35765058 | J:326567
First Author: Paterno G
Year: 2022
Journal: Acta Neuropathol Commun
Title: Reassessment of Neuronal Tau Distribution in Adult Human Brain and Implications for Tau Pathobiology.
Volume: 10
Issue: 1
Pages: 94
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Publication
25261551 | J:216453
First Author: Holmes BB
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Proteopathic tau seeding predicts tauopathy in vivo.
Volume: 111
Issue: 41
Pages: E4376-85
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Publication
21917794 | J:191549
First Author: Yamada K
Year: 2011
Journal: J Neurosci
Title: In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice.
Volume: 31
Issue: 37
Pages: 13110-7
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Publication
37014877 | J:334633
First Author: Amorim IS
Year: 2023
Journal: PLoS One
Title: A seeding-based neuronal model of tau aggregation for use in drug discovery.
Volume: 18
Issue: 4
Pages: e0283941
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Publication
21569847 | J:173243
First Author: Belarbi K
Year: 2011
Journal: Neurobiol Dis
Title: Beneficial effects of exercise in a transgenic mouse model of Alzheimer's disease-like Tau pathology.
Volume: 43
Issue: 2
Pages: 486-94
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Publication
11013246 | J:66831
First Author: Götz J
Year: 2001
Journal: J Biol Chem
Title: Tau filament formation in transgenic mice expressing P301L tau.
Volume: 276
Issue: 1
Pages: 529-34
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Publication
15831501 | J:102396
First Author: David DC
Year: 2005
Journal: J Biol Chem
Title: Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice.
Volume: 280
Issue: 25
Pages: 23802-14
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Publication
19936237 | J:155401
First Author: Ke YD
Year: 2009
Journal: PLoS One
Title: Experimental diabetes mellitus exacerbates tau pathology in a transgenic mouse model of Alzheimer's disease.
Volume: 4
Issue: 11
Pages: e7917
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Publication
18662339 | J:139955
First Author: Deters N
Year: 2008
Journal: Eur J Neurosci
Title: Divergent phosphorylation pattern of tau in P301L tau transgenic mice.
Volume: 28
Issue: 1
Pages: 137-47
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Publication
17690183 | J:124344
First Author: Leroy K
Year: 2007
Journal: Am J Pathol
Title: Early axonopathy preceding neurofibrillary tangles in mutant tau transgenic mice.
Volume: 171
Issue: 3
Pages: 976-92
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Publication
16571759 | J:107246
First Author: Boekhoorn K
Year: 2006
Journal: J Neurosci
Title: Improved long-term potentiation and memory in young tau-P301L transgenic mice before onset of hyperphosphorylation and tauopathy.
Volume: 26
Issue: 13
Pages: 3514-23
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Publication
33044112 | J:313635
First Author: Fang C
Year: 2021
Journal: Autophagy
Title: SSH1 impedes SQSTM1/p62 flux and MAPT/Tau clearance independent of CFL (cofilin) activation.
Volume: 17
Issue: 9
Pages: 2144-2165
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Publication
35212707 | J:328365
 
First Author: Ishida K
Year: 2022
Journal: J Exp Med
Title: Glymphatic system clears extracellular tau and protects from tau aggregation and neurodegeneration.
Volume: 219
Issue: 3
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Publication
33472038 | J:303506
First Author: Largo-Barrientos P
Year: 2021
Journal: Neuron
Title: Lowering Synaptogyrin-3 expression rescues Tau-induced memory defects and synaptic loss in the presence of microglial activation.
Volume: 109
Issue: 5
Pages: 767-777.e5
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Publication
32683652 | J:312810
First Author: Lidón L
Year: 2020
Journal: Mol Neurobiol
Title: Tau Protein as a New Regulator of Cellular Prion Protein Transcription.
Volume: 57
Issue: 10
Pages: 4170-4186
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Publication
30818066 | J:279567
 
First Author: Houben S
Year: 2019
Journal: Neurobiol Dis
Title: Genetic ablation of tau in postnatal neurons rescues decreased adult hippocampal neurogenesis in a tauopathy model.
Volume: 127
Pages: 131-141
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Publication
24376810 | J:209849
First Author: Borghgraef P
Year: 2013
Journal: PLoS One
Title: Increasing brain protein O-GlcNAc-ylation mitigates breathing defects and mortality of Tau.P301L mice.
Volume: 8
Issue: 12
Pages: e84442
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Publication
21281813 | J:169074
First Author: Ando K
Year: 2011
Journal: Am J Pathol
Title: Accelerated human mutant tau aggregation by knocking out murine tau in a transgenic mouse model.
Volume: 178
Issue: 2
Pages: 803-16
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Publication
33555315 | J:313261
First Author: Hinman JD
Year: 2021
Journal: Hum Mol Genet
Title: miR-142-3p regulates cortical oligodendrocyte gene co-expression networks associated with tauopathy.
Volume: 30
Issue: 1
Pages: 103-118
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Publication
30463906 | J:272570
First Author: Koerner MV
Year: 2018
Journal: Genes Dev
Title: Toxicity of overexpressed MeCP2 is independent of HDAC3 activity.
Volume: 32
Issue: 23-24
Pages: 1514-1524
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Publication
19074461 | J:145003
First Author: Pacheco CD
Year: 2009
Journal: Hum Mol Genet
Title: Tau deletion exacerbates the phenotype of Niemann-Pick type C mice and implicates autophagy in pathogenesis.
Volume: 18
Issue: 5
Pages: 956-65
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Publication
25707508 | J:326933
First Author: Miyazaki T
Year: 2015
Journal: Cell Tissue Res
Title: Microtubule-associated protein tau (Mapt) is expressed in terminally differentiated odontoblasts and severely down-regulated in morphologically disturbed odontoblasts of Runx2 transgenic mice.
Volume: 361
Issue: 2
Pages: 457-66
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Publication
16807328 | J:110038
First Author: Dickey CA
Year: 2006
Journal: J Neurosci
Title: Deletion of the ubiquitin ligase CHIP leads to the accumulation, but not the aggregation, of both endogenous phospho- and caspase-3-cleaved tau species.
Volume: 26
Issue: 26
Pages: 6985-96
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Publication
23425014 | J:218147
First Author: Caccamo A
Year: 2013
Journal: Aging Cell
Title: mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies.
Volume: 12
Issue: 3
Pages: 370-80
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Publication
25326800 | J:227814
First Author: Zhang Z
Year: 2014
Journal: Nat Med
Title: Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease.
Volume: 20
Issue: 11
Pages: 1254-62
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Publication
10973990 | J:77655
First Author: Takei Y
Year: 2000
Journal: J Cell Biol
Title: Defects in axonal elongation and neuronal migration in mice with disrupted tau and map1b genes.
Volume: 150
Issue: 5
Pages: 989-1000
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Publication
24849348 | J:211349
First Author: Ma QL
Year: 2014
Journal: J Neurosci
Title: Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.
Volume: 34
Issue: 21
Pages: 7124-36
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Publication
31673052 | J:284884
First Author: Metaxas A
Year: 2019
Journal: Sci Rep
Title: Ageing and amyloidosis underlie the molecular and pathological alterations of tau in a mouse model of familial Alzheimer's disease.
Volume: 9
Issue: 1
Pages: 15758
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Publication
26089772 | J:288934
 
First Author: Maphis N
Year: 2015
Journal: Front Neurosci
Title: Loss of tau rescues inflammation-mediated neurodegeneration.
Volume: 9
Pages: 196
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Publication
32544086 | J:299500
First Author: Gratuze M
Year: 2020
Journal: J Clin Invest
Title: Impact of TREM2R47H variant on tau pathology-induced gliosis and neurodegeneration.
Volume: 130
Issue: 9
Pages: 4954-4968
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Publication
28959956 | J:256914
First Author: Shi Y
Year: 2017
Journal: Nature
Title: ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.
Volume: 549
Issue: 7673
Pages: 523-527
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Publication
23418567 | J:197198
First Author: Garringer HJ
Year: 2013
Journal: PLoS One
Title: Increased tau phosphorylation and tau truncation, and decreased synaptophysin levels in mutant BRI2/tau transgenic mice.
Volume: 8
Issue: 2
Pages: e56426
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Publication
15509565 | J:96869
First Author: Terwel D
Year: 2005
Journal: J Biol Chem
Title: Changed conformation of mutant Tau-P301L underlies the moribund tauopathy, absent in progressive, nonlethal axonopathy of Tau-4R/2N transgenic mice.
Volume: 280
Issue: 5
Pages: 3963-73
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Publication
24498342 | J:212846
First Author: Maurin H
Year: 2014
Journal: PLoS One
Title: Early structural and functional defects in synapses and myelinated axons in stratum lacunosum moleculare in two preclinical models for tauopathy.
Volume: 9
Issue: 2
Pages: e87605
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Publication
29608591 | J:261369
First Author: Croft CL
Year: 2018
Journal: PLoS One
Title: Novel monoclonal antibodies targeting the microtubule-binding domain of human tau.
Volume: 13
Issue: 4
Pages: e0195211
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Publication
29859869 | J:270253
 
First Author: Das M
Year: 2018
Journal: Neurobiol Dis
Title: Neuronal levels and sequence of tau modulate the power of brain rhythms.
Volume: 117
Pages: 181-188
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Publication
10595944 | J:100972
First Author: Spittaels K
Year: 1999
Journal: Am J Pathol
Title: Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein.
Volume: 155
Issue: 6
Pages: 2153-65
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Publication
20409077 | J:221852
First Author: Pehar M
Year: 2010
Journal: Aging Cell
Title: Altered longevity-assurance activity of p53:p44 in the mouse causes memory loss, neurodegeneration and premature death.
Volume: 9
Issue: 2
Pages: 174-90
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Allele
Tc(HSA17*)1Mdk | MGI:6729680
Name: transchromosomal, human 17, line 1, Michael Koob
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Publication
25558816 | J:234457
First Author: Xia D
Year: 2015
Journal: Biochim Biophys Acta
Title: Pseudophosphorylation of Tau at distinct epitopes or the presence of the P301L mutation targets the microtubule-associated protein Tau to dendritic spines.
Volume: 1852
Issue: 5
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