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Search results 2201 to 2283 out of 2283 for Mapt

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Type Details Score
Publication
29501742 | J:273677
First Author: Li H
Year: 2018
Journal: Biochem Biophys Res Commun
Title: FTO is involved in Alzheimer's disease by targeting TSC1-mTOR-Tau signaling.
Volume: 498
Issue: 1
Pages: 234-239
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Publication
36843263 | J:338361
First Author: Kim SH
Year: 2023
Journal: Autophagy
Title: Endolysosomal impairment by binding of amyloid beta or MAPT/Tau to V-ATPase and rescue via the HYAL-CD44 axis in Alzheimer disease.
Volume: 19
Issue: 8
Pages: 2318-2337
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Publication
31434879 | J:279495
First Author: Spangenberg E
Year: 2019
Journal: Nat Commun
Title: Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model.
Volume: 10
Issue: 1
Pages: 3758
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Publication
27155503 | J:242424
First Author: Hargis KE
Year: 2017
Journal: Behav Brain Res
Title: Transcriptional signatures of brain aging and Alzheimer's disease: What are our rodent models telling us?
Volume: 322
Issue: Pt B
Pages: 311-328
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Publication
21829458 | J:284814
First Author: Bianchi FT
Year: 2011
Journal: PLoS One
Title: The collagen chaperone HSP47 is a new interactor of APP that affects the levels of extracellular beta-amyloid peptides.
Volume: 6
Issue: 7
Pages: e22370
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Publication
26214837 | J:228830
First Author: Zenaro E
Year: 2015
Journal: Nat Med
Title: Neutrophils promote Alzheimer's disease-like pathology and cognitive decline via LFA-1 integrin.
Volume: 21
Issue: 8
Pages: 880-6
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Publication
32745992 | J:311234
 
First Author: Crapser JD
Year: 2020
Journal: EBioMedicine
Title: Microglia facilitate loss of perineuronal nets in the Alzheimer's disease brain.
Volume: 58
Pages: 102919
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Publication
33893290 | J:304519
First Author: Baglietto-Vargas D
Year: 2021
Journal: Nat Commun
Title: Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer's disease-like pathology.
Volume: 12
Issue: 1
Pages: 2421
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Publication
20133765 | J:157545
First Author: Bryleva EY
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD.
Volume: 107
Issue: 7
Pages: 3081-6
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Publication
34303222 | J:311302
 
First Author: Russo ML
Year: 2021
Journal: Neurobiol Aging
Title: Variability in sub-threshold signaling linked to Alzheimer's disease emerges with age and amyloid plaque deposition in mouse ventral CA1 pyramidal neurons.
Volume: 106
Pages: 207-222
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Publication
21235806 | J:194454
First Author: Fonseca MI
Year: 2011
Journal: J Neuroinflammation
Title: Contribution of complement activation pathways to neuropathology differs among mouse models of Alzheimer's disease.
Volume: 8
Issue: 1
Pages: 4
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Publication
18800967 | J:141307
First Author: Ribe EM
Year: 2008
Journal: Biochem J
Title: Mechanisms of neuronal death in disease: defining the models and the players.
Volume: 415
Issue: 2
Pages: 165-82
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Publication
31164420 | J:279242
First Author: Bahn G
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: NRF2/ARE pathway negatively regulates BACE1 expression and ameliorates cognitive deficits in mouse Alzheimer's models.
Volume: 116
Issue: 25
Pages: 12516-12523
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Publication
20305648 | J:159680
First Author: Fuhrmann M
Year: 2010
Journal: Nat Neurosci
Title: Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease.
Volume: 13
Issue: 4
Pages: 411-3
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Publication
29024660 | J:253213
First Author: Zhao Y
Year: 2017
Journal: Neuron
Title: Amyloid Beta Peptides Block New Synapse Assembly by Nogo Receptor-Mediated Inhibition of T-Type Calcium Channels.
Volume: 96
Issue: 2
Pages: 355-372.e6
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Publication
33287900 | J:313473
First Author: Bevan RJ
Year: 2020
Journal: Acta Neuropathol Commun
Title: Retinal ganglion cell degeneration correlates with hippocampal spine loss in experimental Alzheimer's disease.
Volume: 8
Issue: 1
Pages: 216
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Publication
26159193 | J:264838
First Author: Plagg B
Year: 2015
Journal: Curr Alzheimer Res
Title: Increased Acetylation of Histone H4 at Lysine 12 (H4K12) in Monocytes of Transgenic Alzheimer's Mice and in Human Patients.
Volume: 12
Issue: 8
Pages: 752-60
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Publication
33192524 | J:313486
 
First Author: Iyaswamy A
Year: 2020
Journal: Front Pharmacol
Title: Yuan-Hu Zhi Tong Prescription Mitigates Tau Pathology and Alleviates Memory Deficiency in the Preclinical Models of Alzheimer's Disease.
Volume: 11
Pages: 584770
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32832679 | J:327386
First Author: Chen C
Year: 2020
Journal: Sci Adv
Title: Gut dysbiosis contributes to amyloid pathology, associated with C/EBPβ/AEP signaling activation in Alzheimer's disease mouse model.
Volume: 6
Issue: 31
Pages: eaba0466
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Publication
37060096 | J:335721
First Author: Wu D
Year: 2023
Journal: Mol Neurodegener
Title: Targeting a vulnerable septum-hippocampus cholinergic circuit in a critical time window ameliorates tau-impaired memory consolidation.
Volume: 18
Issue: 1
Pages: 23
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Publication
30635592 | J:275422
First Author: Creighton SD
Year: 2019
Journal: Sci Rep
Title: Dissociable cognitive impairments in two strains of transgenic Alzheimer's disease mice revealed by a battery of object-based tests.
Volume: 9
Issue: 1
Pages: 57
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Publication
30525042 | J:268837
 
First Author: Sabbir MG
Year: 2018
Journal: Front Mol Biosci
Title: Loss of Ca2+/Calmodulin Dependent Protein Kinase Kinase 2 Leads to Aberrant Transferrin Phosphorylation and Trafficking: A Potential Biomarker for Alzheimer's Disease.
Volume: 5
Pages: 99
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Publication
37118504 | J:337860
First Author: Dejanovic B
Year: 2022
Journal: Nat Aging
Title: Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer's disease mouse models.
Volume: 2
Issue: 9
Pages: 837-850
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Publication
31076275 | J:276144
First Author: Adaikkan C
Year: 2019
Journal: Neuron
Title: Gamma Entrainment Binds Higher-Order Brain Regions and Offers Neuroprotection.
Volume: 102
Issue: 5
Pages: 929-943.e8
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Publication
37315555 | J:339356
First Author: Sheehan PW
Year: 2023
Journal: Neuron
Title: An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology.
Volume: 111
Issue: 15
Pages: 2383-2398.e7
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Publication
37117599 | J:339502
First Author: March-Diaz R
Year: 2021
Journal: Nat Aging
Title: Hypoxia compromises the mitochondrial metabolism of Alzheimer's disease microglia via HIF1.
Volume: 1
Issue: 4
Pages: 385-399
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Publication
33891876 | J:306299
First Author: Bourdenx M
Year: 2021
Journal: Cell
Title: Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome.
Volume: 184
Issue: 10
Pages: 2696-2714.e25
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Publication
23147109 | J:203656
 
First Author: Waite MR
Year: 2013
Journal: Mol Cell Neurosci
Title: Pleiotropic and isoform-specific functions for Pitx2 in superior colliculus and hypothalamic neuronal development.
Volume: 52
Pages: 128-39
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Publication
28814543 | J:250614
 
First Author: Le Pichon CE
Year: 2017
Journal: Sci Transl Med
Title: Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease.
Volume: 9
Issue: 403
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Genotype
Genotype
Symbol: Cx3cr1/Cx3cr1 Psen1/Psen1 Tg(APPSwe,tauP301L)1Lfa/? Tg(Thy1-YFP)HJrs/?
Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cx3cr1/Cx3cr1<+> Psen1/Psen1 Tg(APPSwe,tauP301L)1Lfa/? Tg(Thy1-YFP)HJrs/?
Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Publication
25002035 | J:218071
First Author: Orre M
Year: 2014
Journal: Neurobiol Aging
Title: Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction.
Volume: 35
Issue: 12
Pages: 2746-2760
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Publication
35236988 | J:338102
First Author: Xiong J
Year: 2022
Journal: Nature
Title: FSH blockade improves cognition in mice with Alzheimer's disease.
Volume: 603
Issue: 7901
Pages: 470-476
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Publication
27425031 | J:255474
First Author: Kamphuis W
Year: 2016
Journal: Biochim Biophys Acta
Title: Transcriptional profiling of CD11c-positive microglia accumulating around amyloid plaques in a mouse model for Alzheimer's disease.
Volume: 1862
Issue: 10
Pages: 1847-60
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Publication
37358017 | J:339350
First Author: Marinho D
Year: 2023
Journal: Aging Cell
Title: Reduction of class I histone deacetylases ameliorates ER-mitochondria cross-talk in Alzheimer's disease.
Volume: 22
Issue: 8
Pages: e13895
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Publication
23432034 | J:199628
First Author: Chakravarthy B
Year: 2013
Journal: J Neurochem
Title: A synthetic peptide corresponding to a region of the human pericentriolar material 1 (PCM-1) protein binds β-amyloid (Aβ1-42 ) oligomers.
Volume: 126
Issue: 3
Pages: 415-24
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Publication
29393544 | J:258731
First Author: Valny M
Year: 2018
Journal: Glia
Title: A single-cell analysis reveals multiple roles of oligodendroglial lineage cells during post-ischemic regeneration.
Volume: 66
Issue: 5
Pages: 1068-1081
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Publication
27425620 | J:238659
First Author: Liebmann T
Year: 2016
Journal: Cell Rep
Title: Three-Dimensional Study of Alzheimer's Disease Hallmarks Using the iDISCO Clearing Method.
Volume: 16
Issue: 4
Pages: 1138-1152
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Publication
29113959 | J:260831
 
First Author: Lardenoije R
Year: 2018
Journal: Mol Cell Neurosci
Title: Age-related epigenetic changes in hippocampal subregions of four animal models of Alzheimer's disease.
Volume: 86
Pages: 1-15
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Publication
31467276 | J:279320
First Author: Jadiya P
Year: 2019
Journal: Nat Commun
Title: Impaired mitochondrial calcium efflux contributes to disease progression in models of Alzheimer's disease.
Volume: 10
Issue: 1
Pages: 3885
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Publication
25617315 | J:232678
First Author: Clarke JR
Year: 2015
Journal: EMBO Mol Med
Title: Alzheimer-associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation.
Volume: 7
Issue: 2
Pages: 190-210
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Publication
22912745 | J:189978
First Author: Kamphuis W
Year: 2012
Journal: PLoS One
Title: GFAP isoforms in adult mouse brain with a focus on neurogenic astrocytes and reactive astrogliosis in mouse models of Alzheimer disease.
Volume: 7
Issue: 8
Pages: e42823
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Publication
26982728 | J:232713
First Author: Roy DS
Year: 2016
Journal: Nature
Title: Memory retrieval by activating engram cells in mouse models of early Alzheimer's disease.
Volume: 531
Issue: 7595
Pages: 508-12
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Publication
32098978 | J:293886
First Author: Jiang H
Year: 2020
Journal: Sci Rep
Title: Live Neuron High-Content Screening Reveals Synaptotoxic Activity in Alzheimer Mouse Model Homogenates.
Volume: 10
Issue: 1
Pages: 3412
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Publication
26280122 | J:228804
First Author: Ceglia I
Year: 2015
Journal: Nat Med
Title: APP intracellular domain-WAVE1 pathway reduces amyloid-β production.
Volume: 21
Issue: 9
Pages: 1054-9
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Publication
27210751 | J:235961
First Author: Hamilton A
Year: 2016
Journal: Cell Rep
Title: Chronic Pharmacological mGluR5 Inhibition Prevents Cognitive Impairment and Reduces Pathogenesis in an Alzheimer Disease Mouse Model.
Volume: 15
Issue: 9
Pages: 1859-65
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Publication
28683325 | J:254503
First Author: Haas LT
Year: 2017
Journal: Cell Rep
Title: Silent Allosteric Modulation of mGluR5 Maintains Glutamate Signaling while Rescuing Alzheimer's Mouse Phenotypes.
Volume: 20
Issue: 1
Pages: 76-88
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Publication
29211722 | J:274288
First Author: Sorrentino V
Year: 2017
Journal: Nature
Title: Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity.
Volume: 552
Issue: 7684
Pages: 187-193
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Publication
33846335 | J:311263
First Author: Kim K
Year: 2021
Journal: Nat Commun
Title: Therapeutic B-cell depletion reverses progression of Alzheimer's disease.
Volume: 12
Issue: 1
Pages: 2185
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Publication
25331900 | J:216662
First Author: Chow HM
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: CDK5 activator protein p25 preferentially binds and activates GSK3β.
Volume: 111
Issue: 45
Pages: E4887-95
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Publication
33663578 | J:311283
First Author: Chen M
Year: 2021
Journal: Mol Neurodegener
Title: Enhancing GABAergic signaling ameliorates aberrant gamma oscillations of olfactory bulb in AD mouse models.
Volume: 16
Issue: 1
Pages: 14
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Publication
24684630 | J:214689
First Author: Kuwabara Y
Year: 2014
Journal: J Neurochem
Title: Impairments of long-term depression induction and motor coordination precede Aβ accumulation in the cerebellum of APPswe/PS1dE9 double transgenic mice.
Volume: 130
Issue: 3
Pages: 432-43
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Publication
25673868 | J:219873
First Author: Ben Haim L
Year: 2015
Journal: J Neurosci
Title: The JAK/STAT3 pathway is a common inducer of astrocyte reactivity in Alzheimer's and Huntington's diseases.
Volume: 35
Issue: 6
Pages: 2817-29
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Publication
33955647 | J:311343
First Author: Wu L
Year: 2021
Journal: Aging Cell
Title: Therapeutic efficacy of novel memantine nitrate MN-08 in animal models of Alzheimer's disease.
Volume: 20
Issue: 6
Pages: e13371
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Publication
30742114 | J:277544
First Author: Fang EF
Year: 2019
Journal: Nat Neurosci
Title: Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.
Volume: 22
Issue: 3
Pages: 401-412
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Publication
27752775 | J:311368
First Author: Jan A
Year: 2017
Journal: Acta Neuropathol
Title: eEF2K inhibition blocks Aβ42 neurotoxicity by promoting an NRF2 antioxidant response.
Volume: 133
Issue: 1
Pages: 101-119
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Publication
30050035 | J:264863
First Author: Wei Y
Year: 2018
Journal: Cell Death Dis
Title: Oxidation of KCNB1 channels in the human brain and in mouse model of Alzheimer's disease.
Volume: 9
Issue: 8
Pages: 820
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Publication
29298895 | J:262527
First Author: Hashimoto S
Year: 2018
Journal: J Biol Chem
Title: Endoplasmic reticulum stress responses in mouse models of Alzheimer's disease: Overexpression paradigm versus knockin paradigm.
Volume: 293
Issue: 9
Pages: 3118-3125
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Publication
37143894 | J:337547
 
First Author: Tiberi A
Year: 2023
Journal: Front Cell Dev Biol
Title: Reduced levels of NGF shift astrocytes toward a neurotoxic phenotype.
Volume: 11
Pages: 1165125
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Publication
34505007 | J:313520
First Author: Aguilar-Pineda JA
Year: 2021
Journal: iScience
Title: Vascular smooth muscle cell dysfunction contribute to neuroinflammation and Tau hyperphosphorylation in Alzheimer disease.
Volume: 24
Issue: 9
Pages: 102993
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Publication
21925604 | J:189488
First Author: Waite MR
Year: 2012
Journal: Mol Cell Neurosci
Title: Distinct populations of GABAergic neurons in mouse rhombomere 1 express but do not require the homeodomain transcription factor PITX2.
Volume: 49
Issue: 1
Pages: 32-43
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Publication
29026079 | J:254398
First Author: Iwata T
Year: 2017
Journal: Nat Commun
Title: A long-range cis-regulatory element for class I odorant receptor genes.
Volume: 8
Issue: 1
Pages: 885
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Publication
37557174 | J:339867
     
First Author: Prigge CL
Year: 2023
Journal: Dev Cell
Title: Rejection of inappropriate synaptic partners in mouse retina mediated by transcellular FLRT2-UNC5 signaling.
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Publication
25622143 | J:274055
First Author: Orr AG
Year: 2015
Journal: Nat Neurosci
Title: Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory.
Volume: 18
Issue: 3
Pages: 423-34
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Publication
32392471 | J:301449
First Author: Sauerbeck AD
Year: 2020
Journal: Neuron
Title: SEQUIN Multiscale Imaging of Mammalian Central Synapses Reveals Loss of Synaptic Connectivity Resulting from Diffuse Traumatic Brain Injury.
Volume: 107
Issue: 2
Pages: 257-273.e5
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Publication
26931567 | J:233816
First Author: Maeda S
Year: 2016
Journal: EMBO Rep
Title: Expression of A152T human tau causes age-dependent neuronal dysfunction and loss in transgenic mice.
Volume: 17
Issue: 4
Pages: 530-51
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Publication
30414727 | J:272048
 
First Author: Midani-Kurçak JS
Year: 2019
Journal: Brain Res
Title: Effect of tau-pathology on charged multivesicular body protein 2b (CHMP2B).
Volume: 1706
Pages: 224-236
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Publication
34301831 | J:309391
First Author: Fleitas C
Year: 2021
Journal: J Neurosci
Title: FLRT2 and FLRT3 Cooperate in Maintaining the Tangential Migratory Streams of Cortical Interneurons during Development.
Volume: 41
Issue: 35
Pages: 7350-7362
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Publication
37028406 | J:334726
First Author: Li YD
Year: 2023
Journal: Cell Stem Cell
Title: Activation of hypothalamic-enhanced adult-born neurons restores cognitive and affective function in Alzheimer's disease.
Volume: 30
Issue: 4
Pages: 415-432.e6
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Publication
26365177 | J:228348
First Author: Ishii M
Year: 2015
Journal: Cell Metab
Title: Metabolic and Non-Cognitive Manifestations of Alzheimer's Disease: The Hypothalamus as Both Culprit and Target of Pathology.
Volume: 22
Issue: 5
Pages: 761-76
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Publication
24305500 | J:286212
First Author: Reinert J
Year: 2014
Journal: J Alzheimers Dis
Title: Aβ38 in the brains of patients with sporadic and familial Alzheimer's disease and transgenic mouse models.
Volume: 39
Issue: 4
Pages: 871-81
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Publication
19057621 | J:158080
First Author: Rodríguez JJ
Year: 2009
Journal: Cell Death Differ
Title: Astroglia in dementia and Alzheimer's disease.
Volume: 16
Issue: 3
Pages: 378-85
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Publication
32727580 | J:311717
First Author: Kumar S
Year: 2020
Journal: Acta Neuropathol Commun
Title: Phosphorylated Aβ peptides in human Down syndrome brain and different Alzheimer's-like mouse models.
Volume: 8
Issue: 1
Pages: 118
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Publication
28694463 | J:249724
First Author: Dudeffant C
Year: 2017
Journal: Sci Rep
Title: Contrast-enhanced MR microscopy of amyloid plaques in five mouse models of amyloidosis and in human Alzheimer's disease brains.
Volume: 7
Issue: 1
Pages: 4955
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Publication
31213067 | J:277676
 
First Author: Findley CA
Year: 2019
Journal: ASN Neuro
Title: Amyloid Beta-Related Alterations to Glutamate Signaling Dynamics During Alzheimer's Disease Progression.
Volume: 11
Pages: 1759091419855541
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Publication
27022623 | J:240236
 
First Author: Shen X
Year: 2016
Journal: eNeuro
Title: Neurons in Vulnerable Regions of the Alzheimer's Disease Brain Display Reduced ATM Signaling.
Volume: 3
Issue: 1
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Publication
37463212 | J:344394
First Author: Cazzaro S
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Slingshot homolog-1-mediated Nrf2 sequestration tips the balance from neuroprotection to neurodegeneration in Alzheimer's disease.
Volume: 120
Issue: 30
Pages: e2217128120
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Publication
23747948 | J:199082
First Author: Frost JL
Year: 2013
Journal: Am J Pathol
Title: Pyroglutamate-3 amyloid-β deposition in the brains of humans, non-human primates, canines, and Alzheimer disease-like transgenic mouse models.
Volume: 183
Issue: 2
Pages: 369-81
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Publication
23833557 | J:202532
First Author: Lee JE
Year: 2013
Journal: Exp Neurobiol
Title: An update of animal models of Alzheimer disease with a reevaluation of plaque depositions.
Volume: 22
Issue: 2
Pages: 84-95
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Publication
25654552 | J:219892
First Author: Frake RA
Year: 2015
Journal: J Clin Invest
Title: Autophagy and neurodegeneration.
Volume: 125
Issue: 1
Pages: 65-74
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Publication
- | J:94077
     
First Author: Mutant Mouse Regional Resource Centers
Year: 2004
Journal: Unpublished
Title: Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC)
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Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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Publication
- | J:100256
     
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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