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Search results 501 to 600 out of 639 for Cd47

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Type Details Score
Publication
36797364 | J:334808
First Author: Gwag T
Year: 2023
Journal: Sci Rep
Title: CD47 antisense oligonucleotide treatment attenuates obesity and its-associated metabolic dysfunction.
Volume: 13
Issue: 1
Pages: 2748
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Allele
Cd47<em2(CD47)Smoc> | MGI:7288836
Name: CD47 antigen (Rh-related antigen, integrin-associated signal transducer); endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence, Inserted expressed sequence
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Publication
31689243 | J:291028
 
First Author: Tsao LC
Year: 2019
Journal: JCI Insight
Title: CD47 blockade augmentation of trastuzumab antitumor efficacy dependent on antibody-dependent cellular phagocytosis.
Volume: 4
Issue: 24
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Allele
Cd47<em1Smoc> | MGI:7288835
Name: CD47 antigen (Rh-related antigen, integrin-associated signal transducer); endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
32294445 | J:300915
First Author: Cham LB
Year: 2020
Journal: Cell Rep
Title: Immunotherapeutic Blockade of CD47 Inhibitory Signaling Enhances Innate and Adaptive Immune Responses to Viral Infection.
Volume: 31
Issue: 2
Pages: 107494
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Publication
34559187 | J:347380
 
First Author: Kosaka A
Year: 2021
Journal: J Exp Med
Title: CD47 blockade enhances the efficacy of intratumoral STING-targeting therapy by activating phagocytes.
Volume: 218
Issue: 11
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Publication
31996683 | J:286008
First Author: Li Y
Year: 2020
Journal: Nat Commun
Title: Vaccination with CD47 deficient tumor cells elicits an antitumor immune response in mice.
Volume: 11
Issue: 1
Pages: 581
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Publication
29042481 | J:259049
 
First Author: Meijles DN
Year: 2017
Journal: Sci Signal
Title: The matricellular protein TSP1 promotes human and mouse endothelial cell senescence through CD47 and Nox1.
Volume: 10
Issue: 501
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Publication
30872703 | J:275697
First Author: Lian S
Year: 2019
Journal: Sci Rep
Title: Dual blockage of both PD-L1 and CD47 enhances immunotherapy against circulating tumor cells.
Volume: 9
Issue: 1
Pages: 4532
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Publication
34349035 | J:318715
 
First Author: Zhang A
Year: 2021
Journal: Sci Transl Med
Title: Dual targeting of CTLA-4 and CD47 on Treg cells promotes immunity against solid tumors.
Volume: 13
Issue: 605
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Allele
Cd47<em3(CD47)Smoc> | MGI:7288837
Name: CD47 antigen (Rh-related antigen, integrin-associated signal transducer); endonuclease-mediated mutation 3, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Cd47<tm1Smoc> | MGI:7288838
Name: CD47 antigen (Rh-related antigen, integrin-associated signal transducer); targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Publication
15359629 | -
First Author: Oldenborg PA
Year: 2004
Journal: Leuk Lymphoma
Title: Role of CD47 in erythroid cells and in autoimmunity.
Volume: 45
Issue: 7
Pages: 1319-27
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Publication
19632179 | J:151392
First Author: Majeti R
Year: 2009
Journal: Cell
Title: CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells.
Volume: 138
Issue: 2
Pages: 286-99
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Publication
19004835 | J:145567
First Author: Isenberg JS
Year: 2009
Journal: J Biol Chem
Title: Differential interactions of thrombospondin-1, -2, and -4 with CD47 and effects on cGMP signaling and ischemic injury responses.
Volume: 284
Issue: 2
Pages: 1116-25
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Strain
MGI:6354645 | C57BL/6J-Cd47<em2(CD47)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Publication
12862048 | J:81758
First Author: Shahein YE
Year: 2002
Journal: Cytogenet Genome Res
Title: Assignment of the CD47 gene to pig chromosome band 13q42-->1/2q46 with somatic cell hybrids.
Volume: 97
Issue: 3-4
Pages: 276E
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Strain
MGI:6354646 | C57BL/6J-Cd47<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Publication
33836556 | J:303264
 
First Author: Torrez Dulgeroff LB
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: CD47 blockade reduces the pathologic features of experimental cerebral malaria and promotes survival of hosts with Plasmodium infection.
Volume: 118
Issue: 11
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Interaction Experiment
Murata T (2006)
Description: CD47 promotes neuronal development through Src- and FRG/Vav2-mediated activation of Rac and Cdc42.
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Publication
34758632 | J:341291
First Author: Mueller PA
Year: 2022
Journal: Arterioscler Thromb Vasc Biol
Title: Macrophage LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Is Required for the Effect of CD47 Blockade on Efferocytosis and Atherogenesis-Brief Report.
Volume: 42
Issue: 1
Pages: e1-e9
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Allele
Cd47<tm1Fpl> | MGI:1861955
Name: CD47 antigen (Rh-related antigen, integrin-associated signal transducer); targeted mutation 1, Frederik P Lindberg
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
9504415 | -
First Author: Furusawa T
Year: 1998
Journal: J Biochem
Title: Integrin-associated protein (IAP, also termed CD47) is involved in stroma-supported erythropoiesis.
Volume: 123
Issue: 1
Pages: 101-6
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Strain
MGI:6428055 | Balb/c-Cd47<em1(CD47)/Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Cd47<+> | MGI:2180893
 
Name: CD47 antigen (Rh-related antigen, integrin-associated signal transducer); wild type
Allele Type: Not Specified
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GO Term
GO:0070357 | alphav-beta3 integrin-CD47 complex
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Strain
MGI:2165071 | B6.129S7-Cd47<tm1Fpl>/J
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:4940072 | C.129S7-Cd47<tm1Fpl>
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:4940103 | NOD.129S7-Cd47<tm1Fpl>
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:4430575 | B6.129S7-Cd47<tm1Fpl>
Attribute String: congenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Cd47/Cd47
Background: involves: 129S7/SvEvBrd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd47/Cd47
Background: B6.129S7-Cd47
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd47/Cd47
Background: C.129S7-Cd47
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd47/Cd47
Background: NOD.129S7-Cd47
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd47/Cd47
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd47/Cd47
Background: involves: 129S7/SvEvBrd * C57BL/6JNarl
Zygosity: hm
Has Mutant Allele: true
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GO Term
GO:0070770 | alphaIIb-beta3 integrin-CD47-FAK complex
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GO Term
GO:0070771 | alphaIIb-beta3 integrin-CD47-Src complex
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GO Term
GO:0071083 | alphaV-beta3 integrin-CD47-FCER2 complex
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Allele
Cd47<em2Idmo> | MGI:5903934
Name: CD47 antigen (Rh-related antigen, integrin-associated signal transducer); endonuclease-mediated mutation 2, Beijing IDMO
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
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Allele
Cd47<em1Idmo> | MGI:5903933
Name: CD47 antigen (Rh-related antigen, integrin-associated signal transducer); endonuclease-mediated mutation 1, Beijing IDMO
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
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Allele
Cd47<em22Gpt> | MGI:7296596
Name: CD47 antigen (Rh-related antigen, integrin-associated signal transducer); endonuclease-mediated mutation 22, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Cd47<em1(CD47)Gpt> | MGI:7296592
Name: CD47 antigen (Rh-related antigen, integrin-associated signal transducer); endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Cd47<em4Gpt> | MGI:7296595
Name: CD47 antigen (Rh-related antigen, integrin-associated signal transducer); endonuclease-mediated mutation 4, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Cd47<em3Idmo> | MGI:5903935
Name: CD47 antigen (Rh-related antigen, integrin-associated signal transducer); endonuclease-mediated mutation 3, Beijing IDMO
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
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Allele
Cd47<em2Cya> | MGI:7582859
Name: CD47 antigen (Rh-related antigen, integrin-associated signal transducer); endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Cd47<em2(CD47)Gpt> | MGI:7296593
Name: CD47 antigen (Rh-related antigen, integrin-associated signal transducer); endonuclease-mediated mutation 2, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Cd47<em1Hwl> | MGI:6363068
Name: CD47 antigen (Rh-related antigen, integrin-associated signal transducer); endonuclease-mediated mutation 1, Han-Woong Lee
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Cd47<em3(CD47)Gpt> | MGI:7296594
Name: CD47 antigen (Rh-related antigen, integrin-associated signal transducer); endonuclease-mediated mutation 3, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Cd47<tm1.1Mato> | MGI:7262735
Name: CD47 antigen (Rh-related antigen, integrin-associated signal transducer); targeted mutation 1.1, Takashi Matozaki
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Genotype
Genotype
Symbol: Cd47/Cd47<+>
Background: B6.129S7-Cd47
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd47/Cd47<+>
Background: involves: 129S7/SvEvBrd * C57BL/6JNarl
Zygosity: ht
Has Mutant Allele: true
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Protein Domain
IPR013147 | CD47-like_TM
Type: Domain
Description: Thisentry represents the transmembrane region of CD47 leukocyte antigen and CD47-like proteins A38 from Poxvirus [, , ].
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Publication
12690108 | -
First Author: Lamy L
Year: 2003
Journal: J Biol Chem
Title: CD47 and the 19 kDa interacting protein-3 (BNIP3) in T cell apoptosis.
Volume: 278
Issue: 26
Pages: 23915-21
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Strain
MGI:5903919 | C57BL/6Ncrl-Cd47<em2Idmo>
Attribute String: endonuclease-mediated mutation, mutant strain, coisogenic
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Strain
MGI:5903918 | C57BL/6NCrl-Cd47<em1Idmo>
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:6352450 | BALB/cJGpt-Cd47<em1(CD47)Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Cd47<tm1e(KOMP)Mbp> | MGI:4455394
Name: CD47 antigen (Rh-related antigen, integrin-associated signal transducer); targeted mutation 1e, Mouse Biology Program, UC Davis
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Strain
MGI:5903920 | C57BL/6Ncrl-Cd47<em3Idmo>
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7588576 | C57BL/6J-Cd47<em2Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Cd47<tm1c(KOMP)Mbp> | MGI:6274703
Name: CD47 antigen (Rh-related antigen, integrin-associated signal transducer); targeted mutation 1c, Mouse Biology Program, UC Davis
Allele Type: Targeted
Attribute String: Conditional ready
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Strain
MGI:6349664 | C57BL/6JGpt-Cd47<em2(CD47)Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Cd47<tm1a(KOMP)Mbp> | MGI:4455408
Name: CD47 antigen (Rh-related antigen, integrin-associated signal transducer); targeted mutation 1a, Mouse Biology Program, UC Davis
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Strain
MGI:6363069 | C57BL/6J-Cd47<em1Hwl>/Hwl
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:5609558 | B6.129S-Rag2<tm1Fwa> Cd47<tm1Fpl> Il2rg<tm1Wjl>/J
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:6199071 | B6.129S-Rag1<tm1Mom> Cd47<tm1Fpl> Il2rg<tm1Wjl>/SzJ
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5528885 | B6.129(Cg)-Rag2<tm1Fwa> Cd47<tm1Fpl> Il2rg<tm1Cgn>/KhasJ
Attribute String: congenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Rag2/Rag2 Cd47/Cd47 Il2rg/?
Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S7/SvEvBrd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Allele
Sirpa<Idd13.2-NOD/ShiLt> | MGI:5827684
 
Name: signal-regulatory protein alpha; insulin dependent diabetes susceptibility 13.2-NOD/ShiLt
Allele Type: QTL
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Strain
MGI:7573074 | B6.Cg-Rag2<tm1Fwa> Sgsh<mps3a> Cd47<tm1Fpl> Il2rg<tm1Wjl>/JnolJ
Attribute String: congenic, mutant strain, targeted mutation, spontaneous mutation
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Strain
MGI:6343948 | C57BL/6N-A<tm1Brd> Cd47<tm1c(KOMP)Mbp>/MbpMmucd
Attribute String: mutant strain, coisogenic, targeted mutation
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Strain
MGI:7577158 | C57BL/6JGpt-Sirpa<em2(SIRPA)Gpt> Cd47<em2(CD47)Gpt>/Gpt
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:6865980 | C57BL/6N-A<tm1Brd> Cd47<tm1a(KOMP)Mbp>/Mmucd
Attribute String: coisogenic, mutant strain, targeted mutation
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Strain
MGI:6770236 | BALB/cJGpt-Sirpa<em1(SIRPA)Gpt> Cd47<em3(CD47)Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:6350333 | C57BL/6JGpt-Pdcd1<em1(PDCD1)Gpt> Cd47<em3(CD47)Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Protein Domain
IPR037805 | IgV_CD47
Type: Domain
Description: CD47 was originally identified as integrin-associated protein (IAP). It is a transmembrane glycoprotein that possesses an immunoglobulin variable (IgV) like N-terminal domain, five transmembrane domains and an alternatively spliced C terminus. It functions as a marker of self on erythrocytes, and likely also on other cells, by binding to the inhibitory receptor SIRPalpha []. CD47-induces caspase-independent cell death may be mediated by cytoskeleton reorganisation []. The protein can also act as a thrombospondin receptor [].This entry represents the IgV domain of of CD47. The interaction of CD47 with integrins is dependent on its IgV and transmembrane domains. The IgV domain and transmembrane domain of CD47 have also been found to be sufficient for the association with actin [].
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Publication
23293079 | J:194763
First Author: Yamauchi T
Year: 2013
Journal: Blood
Title: Polymorphic Sirpa is the genetic determinant for NOD-based mouse lines to achieve efficient human cell engraftment.
Volume: 121
Issue: 8
Pages: 1316-25
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Strain
MGI:7382583 | BALB/cJGpt-Pdcd1<em2(PDCD1)Gpt> Sirpa<em2(SIRPA)Gpt> Cd47<em3(CD47)Gpt> Cd274<tm2(CD274)Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation, transgenic
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Publication
- | J:239221
     
First Author: Charles River
Year: 2017
Journal: Scientific info. sheet (http://www.criver.com/files/pdfs/rms/ncg/ncg-mouse-scientific--sheet.aspx)
Title: NOD CRISPR Prkdcil2r Gamma (NCG) Triple-Immunodeficient Mouse Model
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Strain
MGI:7329783 | B6.Cg-Rag2<tm1Fwa> Sirpa<Idd13.2-NOD/ShiLt> II2rg<tm1Wjl>/Kyu
Attribute String: congenic, mutant strain, targeted mutation
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Publication
27499200 | J:327242
First Author: Yurino A
Year: 2016
Journal: Stem Cell Reports
Title: Enhanced Reconstitution of Human Erythropoiesis and Thrombopoiesis in an Immunodeficient Mouse Model with Kit(Wv) Mutations.
Volume: 7
Issue: 3
Pages: 425-438
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Strain
MGI:6474618 | C.Cg-Rag2<tm1Fwa> Sirpa<Idd13.2-NOD/ShiLt> Flt3<tm1Irl> Il2rg<tm1Cgn>/Geno
Attribute String: congenic, targeted mutation, mutant strain, QTL
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Strain
MGI:6474620 | C.Cg-Rag2<tm1Fwa> Sirpa<Idd13.2-NOD/ShiLt> Flt3<tm1Irl> Il2rg<tm1Cgn> Tg(HLA-A/H2-D/B2M)1Bpe/Geno
Attribute String: congenic, targeted mutation, mutant strain, transgenic, QTL
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Strain
MGI:7329944 | B6.Cg-Rag2<tm1Fwa> Sirpa<Idd13.2-NOD/ShiLt> Il2rg<tm1Wjl> Tg(Krt14-Tslp)#Dfk/Pas
Attribute String: congenic, mutant strain, spontaneous mutation, transgenic, targeted mutation
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Strain
MGI:7329802 | B6.Cg-Rag2<tm1Fwa> Sirpa<Idd13.2-NOD/ShiLt> Kit<W-v> Il2rg<tm1Wjl>/Kyu
Attribute String: congenic, mutant strain, targeted mutation, spontaneous mutation
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Publication
30065364 | J:327313
First Author: Li Y
Year: 2018
Journal: Nat Methods
Title: A human immune system mouse model with robust lymph node development.
Volume: 15
Issue: 8
Pages: 623-630
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Publication
30888052 | J:277140
First Author: Masse-Ranson G
Year: 2019
Journal: Eur J Immunol
Title: Accelerated thymopoiesis and improved T-cell responses in HLA-A2/-DR2 transgenic BRGS-based human immune system mice.
Volume: 49
Issue: 6
Pages: 954-965
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Publication
32024825 | J:287661
First Author: Sorkin M
Year: 2020
Journal: Nat Commun
Title: Regulation of heterotopic ossification by monocytes in a mouse model of aberrant wound healing.
Volume: 11
Issue: 1
Pages: 722
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Publication
34020945 | J:314143
 
First Author: Guo Y
Year: 2021
Journal: Sci Adv
Title: Zeb1 induces immune checkpoints to form an immunosuppressive envelope around invading cancer cells.
Volume: 7
Issue: 21
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Publication
17982459 | J:127760
First Author: Takenaka K
Year: 2007
Journal: Nat Immunol
Title: Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells.
Volume: 8
Issue: 12
Pages: 1313-23
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Publication
32814029 | J:305310
First Author: Beguier F
Year: 2020
Journal: Immunity
Title: The 10q26 Risk Haplotype of Age-Related Macular Degeneration Aggravates Subretinal Inflammation by Impairing Monocyte Elimination.
Volume: 53
Issue: 2
Pages: 429-441.e8
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Publication
26057870 | J:237705
First Author: Alvarez-Zarate J
Year: 2015
Journal: PLoS One
Title: Regulation of Phagocyte Migration by Signal Regulatory Protein-Alpha Signaling.
Volume: 10
Issue: 6
Pages: e0127178
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Publication
29881378 | J:337307
 
First Author: Salinas-Muñoz L
Year: 2018
Journal: Front Immunol
Title: Estrogen Receptor-Alpha (ESR1) Governs the Lower Female Reproductive Tract Vulnerability to Candida albicans.
Volume: 9
Pages: 1033
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Publication
30664738 | J:274044
First Author: Liu M
Year: 2019
Journal: Nat Immunol
Title: Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47-mediated 'don't-eat-me' signal.
Volume: 20
Issue: 3
Pages: 265-275
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Publication
32493933 | J:293407
First Author: Cui L
Year: 2020
Journal: Nat Commun
Title: Activation of JUN in fibroblasts promotes pro-fibrotic programme and modulates protective immunity.
Volume: 11
Issue: 1
Pages: 2795
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Publication
25646432 | J:220007
First Author: Feng M
Year: 2015
Journal: Proc Natl Acad Sci U S A
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