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Search results 301 to 400 out of 400 for Mef2d

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Type Details Score
Publication
8993831 | J:38042
First Author: Ferrari S
Year: 1997
Journal: Cell Growth Differ
Title: Absence of MEF2 binding to the A/T-rich element in the muscle creatine kinase (MCK) enhancer correlates with lack of early expression of the MCK gene in embryonic mammalian muscle.
Volume: 8
Issue: 1
Pages: 23-34
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Publication
10207130 | J:54200
First Author: Naya FJ
Year: 1999
Journal: Development
Title: Transcriptional activity of MEF2 during mouse embryogenesis monitored with a MEF2-dependent transgene.
Volume: 126
Issue: 10
Pages: 2045-52
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Publication
21531906 | J:172606
First Author: Vetere G
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Spine growth in the anterior cingulate cortex is necessary for the consolidation of contextual fear memory.
Volume: 108
Issue: 20
Pages: 8456-60
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Publication
22764880 | J:187627
First Author: She H
Year: 2012
Journal: J Neurochem
Title: Neurotoxin-induced selective ubiquitination and regulation of MEF2A isoform in neuronal stress response.
Volume: 122
Issue: 6
Pages: 1203-10
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Publication
24694307 | J:214688
First Author: Daems C
Year: 2014
Journal: Mol Endocrinol
Title: MEF2 is restricted to the male gonad and regulates expression of the orphan nuclear receptor NR4A1.
Volume: 28
Issue: 6
Pages: 886-98
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Publication
17786239 | J:127416
First Author: Potthoff MJ
Year: 2007
Journal: J Clin Invest
Title: Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers.
Volume: 117
Issue: 9
Pages: 2459-67
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Publication
27898394 | J:334208
First Author: Sacilotto N
Year: 2016
Journal: Genes Dev
Title: MEF2 transcription factors are key regulators of sprouting angiogenesis.
Volume: 30
Issue: 20
Pages: 2297-2309
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Publication
20833138 | J:165849
First Author: Choi J
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Histone demethylase LSD1 is required to induce skeletal muscle differentiation by regulating myogenic factors.
Volume: 401
Issue: 3
Pages: 327-32
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Publication
20399744 | J:162523
First Author: Jung SY
Year: 2010
Journal: Biochem Biophys Res Commun
Title: TRIM72, a novel negative feedback regulator of myogenesis, is transcriptionally activated by the synergism of MyoD (or myogenin) and MEF2.
Volume: 396
Issue: 2
Pages: 238-45
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Publication
8900141 | J:36282
First Author: Black BL
Year: 1996
Journal: J Biol Chem
Title: Cooperative transcriptional activation by the neurogenic basic helix-loop-helix protein MASH1 and members of the myocyte enhancer factor-2 (MEF2) family.
Volume: 271
Issue: 43
Pages: 26659-63
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Publication
15601854 | J:95388
First Author: Wang X
Year: 2005
Journal: Mol Cell Biol
Title: Targeted deletion of mek5 causes early embryonic death and defects in the extracellular signal-regulated kinase 5/myocyte enhancer factor 2 cell survival pathway.
Volume: 25
Issue: 1
Pages: 336-45
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Publication
30276662 | J:309438
First Author: Kamath SP
Year: 2019
Journal: Mol Neurobiol
Title: Myocyte Enhancer Factor 2c Regulates Dendritic Complexity and Connectivity of Cerebellar Purkinje Cells.
Volume: 56
Issue: 6
Pages: 4102-4119
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Publication
9162005 | J:40724
First Author: Lin Q
Year: 1997
Journal: Science
Title: Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C.
Volume: 276
Issue: 5317
Pages: 1404-7
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Publication
28641113 | J:255971
First Author: Welsbie DS
Year: 2017
Journal: Neuron
Title: Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in Neurons.
Volume: 94
Issue: 6
Pages: 1142-1154.e6
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Publication
21953612 | J:189468
First Author: Lenoir O
Year: 2011
Journal: Diabetes
Title: Specific control of pancreatic endocrine β- and δ-cell mass by class IIa histone deacetylases HDAC4, HDAC5, and HDAC9.
Volume: 60
Issue: 11
Pages: 2861-71
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Publication
14706451 | J:87785
First Author: Karim SA
Year: 2004
Journal: Genomics
Title: A physical map of the genomic region on mouse chromosome 3 containing the hindshaker (hsh) mutation.
Volume: 83
Issue: 2
Pages: 225-30
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Publication
17336904 | J:119152
First Author: Arnold MA
Year: 2007
Journal: Dev Cell
Title: MEF2C transcription factor controls chondrocyte hypertrophy and bone development.
Volume: 12
Issue: 3
Pages: 377-89
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Publication
20519520 | J:160811
First Author: McDowell KA
Year: 2010
Journal: J Neurosci
Title: Reduced cortical BDNF expression and aberrant memory in Carf knock-out mice.
Volume: 30
Issue: 22
Pages: 7453-65
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Publication
7588068 | J:29279
First Author: Patapoutian A
Year: 1995
Journal: Development
Title: Disruption of the mouse MRF4 gene identifies multiple waves of myogenesis in the myotome.
Volume: 121
Issue: 10
Pages: 3347-58
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Publication
27779093 | J:238731
   
First Author: Harrington AJ
Year: 2016
Journal: Elife
Title: MEF2C regulates cortical inhibitory and excitatory synapses and behaviors relevant to neurodevelopmental disorders.
Volume: 5
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Publication
19782130 | J:164834
First Author: Scott NJ
Year: 2009
Journal: Biochim Biophys Acta
Title: Influence of natriuretic peptide receptor-1 on survival and cardiac hypertrophy during development.
Volume: 1792
Issue: 12
Pages: 1175-84
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Publication
21447557 | J:171273
First Author: Nakajima K
Year: 2011
Journal: Development
Title: Coordinated regulation of differentiation and proliferation of embryonic cardiomyocytes by a jumonji (Jarid2)-cyclin D1 pathway.
Volume: 138
Issue: 9
Pages: 1771-82
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Publication
12130539 | J:77997
First Author: Lazaro JB
Year: 2002
Journal: Genes Dev
Title: Cyclin D-cdk4 activity modulates the subnuclear localization and interaction of MEF2 with SRC-family coactivators during skeletal muscle differentiation.
Volume: 16
Issue: 14
Pages: 1792-805
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Publication
25331958 | J:218799
First Author: Yoon J
Year: 2014
Journal: J Biol Chem
Title: Interferon regulatory factor 8 (IRF8) interacts with the B cell lymphoma 6 (BCL6) corepressor BCOR.
Volume: 289
Issue: 49
Pages: 34250-7
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Publication
21768366 | J:176023
First Author: del Barco Barrantes I
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Genetic analysis of specific and redundant roles for p38alpha and p38beta MAPKs during mouse development.
Volume: 108
Issue: 31
Pages: 12764-9
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Publication
28164238 | J:241786
First Author: Darwich R
Year: 2017
Journal: Hum Mol Genet
Title: KLF13 is a genetic modifier of the Holt-Oram syndrome gene TBX5.
Volume: 26
Issue: 5
Pages: 942-954
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Publication
25915474 | J:222854
First Author: Laguna A
Year: 2015
Journal: Nat Neurosci
Title: Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease.
Volume: 18
Issue: 6
Pages: 826-35
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Publication
22147266 | J:178918
First Author: Rajan S
Year: 2012
Journal: Physiol Genomics
Title: Analysis of early C2C12 myogenesis identifies stably and differentially expressed transcriptional regulators whose knock-down inhibits myoblast differentiation.
Volume: 44
Issue: 2
Pages: 183-97
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Publication
23055939 | J:193641
First Author: Nakano Y
Year: 2012
Journal: PLoS Genet
Title: A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse.
Volume: 8
Issue: 10
Pages: e1002966
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Publication
30995482 | J:281311
First Author: Nakano Y
Year: 2019
Journal: Cell Rep
Title: Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.
Volume: 27
Issue: 3
Pages: 860-871.e8
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Publication
17609113 | J:123923
First Author: Zhou Q
Year: 2007
Journal: Dev Cell
Title: A multipotent progenitor domain guides pancreatic organogenesis.
Volume: 13
Issue: 1
Pages: 103-14
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
32290105 | J:282558
 
First Author: Collin GB
Year: 2020
Journal: Cells
Title: Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.
Volume: 9
Issue: 4
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Publication
22988430 | J:190636
 
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
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Publication
20412781 | J:140465
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
19458239 | J:148843
First Author: Pazyra-Murphy MF
Year: 2009
Journal: J Neurosci
Title: A retrograde neuronal survival response: target-derived neurotrophins regulate MEF2D and bcl-w.
Volume: 29
Issue: 20
Pages: 6700-9
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Publication
37458356 | J:340397
   
First Author: Escós A
Year: 2023
Journal: Elife
Title: p38γ and p38δ modulate innate immune response by regulating MEF2D activation.
Volume: 12
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HT Experiment
GSE61389 | MEF2D drives photoreceptor development through a genome-wide competition for tissue-specific enhancers (RNA-Seq)
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Interaction Experiment
Yang Q (2009)
Description: Regulation of neuronal survival factor MEF2D by chaperone-mediated autophagy.
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Allele
Mef2d<em1Smoc> | MGI:7291021
Name: myocyte enhancer factor 2D; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Interaction Experiment
Gao L (2014)
Description: Oxidation of survival factor MEF2D in neuronal death and Parkinsons disease.
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Strain
MGI:6770937 | C57BL/6-Mef2D<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
24219011 | -
First Author: Gao L
Year: 2014
Journal: Antioxid Redox Signal
Title: Oxidation of survival factor MEF2D in neuronal death and Parkinson's disease.
Volume: 20
Issue: 18
Pages: 2936-48
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Allele
Tg(Myh6-Mef2d)2Eno | MGI:3776912
Name: transgene insertion 2, Eric N Olson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Tg(Myh6-Mef2d)2Eno/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
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Publication
15743823 | -
First Author: Grégoire S
Year: 2005
Journal: Mol Cell Biol
Title: Association with class IIa histone deacetylases upregulates the sumoylation of MEF2 transcription factors.
Volume: 25
Issue: 6
Pages: 2273-87
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Publication
18946085 | -
First Author: Klein UR
Year: 2009
Journal: Mol Biol Cell
Title: RanBP2 and SENP3 function in a mitotic SUMO2/3 conjugation-deconjugation cycle on Borealin.
Volume: 20
Issue: 1
Pages: 410-8
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Publication
19680224 | J:152799
First Author: Huang C
Year: 2009
Journal: EMBO J
Title: SENP3 is responsible for HIF-1 transactivation under mild oxidative stress via p300 de-SUMOylation.
Volume: 28
Issue: 18
Pages: 2748-62
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Protein Domain
IPR037945 | SENP3
Type: Family
Description: Sentrin-specific protease 3 (SENP3, MEROPS identifier C48.003) is an isopeptidase that releases SUMO2 and SUMO3 monomers from sumoylated substrates by hydrolysing the isopeptide bond []. SENP3 is a cysteine peptidase with a fold similar to that of adenain, and has the catalytic triad His, Asp, Cys, the reverse of the order in papain. Among the proteins that are deconjugated by SENP3 are MEF2D [], CDCA8 [], EP300 [], and nucleophosmin []. SENP3 is a component of the 5FMC []and MLL1/MLL complexes [].
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HT Experiment
GSE73560 | Gene expression analysis to identify Klf2 target genes in B-cell progenitors [Klf2_KO]
Series Id: E-GEOD-73560
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE73561 | Gene expression analysis to identify Mef2c/d target genes in B-cell progenitors
Series Id: E-GEOD-73561
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
31532577 | J:290386
First Author: Li C
Year: 2019
Journal: EMBO Mol Med
Title: Nuclear receptor corepressor 1 represses cardiac hypertrophy.
Volume: 11
Issue: 11
Pages: e9127
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Publication
16608850 | -
First Author: Gong L
Year: 2006
Journal: J Biol Chem
Title: Characterization of a family of nucleolar SUMO-specific proteases with preference for SUMO-2 or SUMO-3.
Volume: 281
Issue: 23
Pages: 15869-77
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Publication
22872859 | -
First Author: Fanis P
Year: 2012
Journal: Mol Cell Proteomics
Title: Five friends of methylated chromatin target of protein-arginine-methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation.
Volume: 11
Issue: 11
Pages: 1263-73
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Publication
18259216 | -
First Author: Haindl M
Year: 2008
Journal: EMBO Rep
Title: The nucleolar SUMO-specific protease SENP3 reverses SUMO modification of nucleophosmin and is required for rRNA processing.
Volume: 9
Issue: 3
Pages: 273-9
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Publication
17986259 | J:130254
First Author: Baertschi S
Year: 2007
Journal: FEBS J
Title: Mice with a targeted disruption of the Fgfrl1 gene die at birth due to alterations in the diaphragm.
Volume: 274
Issue: 23
Pages: 6241-53
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Publication
11714752 | J:72760
First Author: Esau C
Year: 2001
Journal: J Exp Med
Title: Deletion of calcineurin and myocyte enhancer factor 2 (MEF2) binding domain of Cabin1 results in enhanced cytokine gene expression in T cells.
Volume: 194
Issue: 10
Pages: 1449-59
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Publication
19812325 | J:153884
First Author: Rashidian J
Year: 2009
Journal: J Neurosci
Title: Essential role of cytoplasmic cdk5 and Prx2 in multiple ischemic injury models, in vivo.
Volume: 29
Issue: 40
Pages: 12497-505
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Publication
30523159 | J:275334
First Author: Li J
Year: 2019
Journal: J Biol Chem
Title: Muscle A-kinase-anchoring protein-β-bound calcineurin toggles active and repressive transcriptional complexes of myocyte enhancer factor 2D.
Volume: 294
Issue: 7
Pages: 2543-2554
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Publication
35794619 | J:345513
First Author: Cao J
Year: 2022
Journal: J Transl Med
Title: Extracellular vesicle miR-32 derived from macrophage promotes arterial calcification in mice with type 2 diabetes via inhibiting VSMC autophagy.
Volume: 20
Issue: 1
Pages: 307
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Publication
28850611 | J:256183
First Author: van den Hoogenhof MMG
Year: 2017
Journal: PLoS One
Title: The RNA-binding protein Rbm38 is dispensable during pressure overload-induced cardiac remodeling in mice.
Volume: 12
Issue: 8
Pages: e0184093
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Publication
31730408 | J:342705
First Author: Schoger E
Year: 2020
Journal: Circ Res
Title: CRISPR-Mediated Activation of Endogenous Gene Expression in the Postnatal Heart.
Volume: 126
Issue: 1
Pages: 6-24
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Protein
Q9EP97
Organism: Mus musculus/domesticus
Length: 568  
Fragment?: false
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Protein
F6Z9L5
Organism: Mus musculus/domesticus
Length: 169  
Fragment?: true
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Publication
15960975 | J:156231
First Author: Dou Y
Year: 2005
Journal: Cell
Title: Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.
Volume: 121
Issue: 6
Pages: 873-85
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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