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Search results 1301 to 1400 out of 1403 for Sirt1

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Type Details Score
Publication
19960022 | J:169429
First Author: Lizé M
Year: 2010
Journal: Cell Death Differ
Title: E2F1-inducible microRNA 449a/b suppresses cell proliferation and promotes apoptosis.
Volume: 17
Issue: 3
Pages: 452-8
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Publication
22601779 | J:187452
First Author: Granata R
Year: 2012
Journal: FASEB J
Title: Obestatin regulates adipocyte function and protects against diet-induced insulin resistance and inflammation.
Volume: 26
Issue: 8
Pages: 3393-411
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Publication
23161884 | J:194687
First Author: Warburton D
Year: 2013
Journal: Am J Physiol Lung Cell Mol Physiol
Title: TGF-β-Smad3 signaling in emphysema and pulmonary fibrosis: an epigenetic aberration of normal development?
Volume: 304
Issue: 2
Pages: L83-5
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Publication
22648295 | J:198172
First Author: Yuan Y
Year: 2012
Journal: Kidney Int
Title: Activation of peroxisome proliferator-activated receptor-γ coactivator 1α ameliorates mitochondrial dysfunction and protects podocytes from aldosterone-induced injury.
Volume: 82
Issue: 7
Pages: 771-89
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Publication
23685142 | J:202637
First Author: Zhao YN
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Resveratrol improves learning and memory in normally aged mice through microRNA-CREB pathway.
Volume: 435
Issue: 4
Pages: 597-602
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Publication
24614171 | J:215123
First Author: Jeong MH
Year: 2014
Journal: PLoS One
Title: β-Lapachone ameliorates lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice.
Volume: 9
Issue: 3
Pages: e91039
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Publication
24793418 | J:217035
First Author: Arora A
Year: 2014
Journal: Biochim Biophys Acta
Title: SIRT2 negatively regulates insulin resistance in C2C12 skeletal muscle cells.
Volume: 1842
Issue: 9
Pages: 1372-8
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Publication
25635942 | J:223838
First Author: Lannes J
Year: 2015
Journal: Mol Endocrinol
Title: Rapid communication: A microRNA-132/212 pathway mediates GnRH activation of FSH expression.
Volume: 29
Issue: 3
Pages: 364-72
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Publication
25916635 | J:230527
First Author: Kim HJ
Year: 2015
Journal: Biochim Biophys Acta
Title: Carbon monoxide protects against hepatic ischemia/reperfusion injury by modulating the miR-34a/SIRT1 pathway.
Volume: 1852
Issue: 7
Pages: 1550-9
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Publication
26170060 | J:231195
First Author: Park SY
Year: 2015
Journal: Biochim Biophys Acta
Title: Suppression of RANKL-induced osteoclast differentiation by cilostazol via SIRT1-induced RANK inhibition.
Volume: 1852
Issue: 10 Pt A
Pages: 2137-44
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Publication
26912776 | J:231515
First Author: Xiong F
Year: 2016
Journal: Biol Open
Title: miR-22 inhibits mouse ovarian granulosa cell apoptosis by targeting SIRT1.
Volume: 5
Issue: 3
Pages: 367-71
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Publication
28192515 | J:252022
First Author: Ganesan R
Year: 2017
Journal: PLoS Pathog
Title: Salmonella Typhimurium disrupts Sirt1/AMPK checkpoint control of mTOR to impair autophagy.
Volume: 13
Issue: 2
Pages: e1006227
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Publication
28809938 | J:248074
First Author: Xie W
Year: 2017
Journal: PLoS One
Title: Perinatal testosterone exposure potentiates vascular dysfunction by ERβ suppression in endothelial progenitor cells.
Volume: 12
Issue: 8
Pages: e0182945
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Publication
28724915 | J:252364
First Author: Wang Z
Year: 2017
Journal: Sci Rep
Title: Quinolinate Phosphoribosyltransferase is an Antiviral Host Factor Against Hepatitis C Virus Infection.
Volume: 7
Issue: 1
Pages: 5876
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Publication
28063949 | J:252221
 
First Author: Manna P
Year: 2017
Journal: Arch Biochem Biophys
Title: Vitamin D supplementation inhibits oxidative stress and upregulate SIRT1/AMPK/GLUT4 cascade in high glucose-treated 3T3L1 adipocytes and in adipose tissue of high fat diet-fed diabetic mice.
Volume: 615
Pages: 22-34
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Publication
27246173 | J:249133
 
First Author: Ding Y
Year: 2016
Journal: Mol Cell Endocrinol
Title: APPL1-mediated activation of STAT3 contributes to inhibitory effect of adiponectin on hepatic gluconeogenesis.
Volume: 433
Pages: 12-9
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Publication
27824104 | J:254490
 
First Author: Zhou L
Year: 2016
Journal: Sci Rep
Title: Degeneration and energy shortage in the suprachiasmatic nucleus underlies the circadian rhythm disturbance in ApoE-/- mice: implications for Alzheimer's disease.
Volume: 6
Pages: 36335
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Publication
28300638 | J:254183
First Author: Zhang J
Year: 2017
Journal: Biochim Biophys Acta
Title: Astaxanthin attenuated pressure overload-induced cardiac dysfunction and myocardial fibrosis: Partially by activating SIRT1.
Volume: 1861
Issue: 7
Pages: 1715-1728
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Publication
27542907 | J:250631
First Author: García-Aguilar A
Year: 2016
Journal: Biochim Biophys Acta
Title: TSC2 N-terminal lysine acetylation status affects to its stability modulating mTORC1 signaling and autophagy.
Volume: 1863
Issue: 11
Pages: 2658-2667
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Publication
28477980 | J:261004
First Author: He Y
Year: 2017
Journal: Exp Cell Res
Title: SIRT6 inhibits TNF-α-induced inflammation of vascular adventitial fibroblasts through ROS and Akt signaling pathway.
Volume: 357
Issue: 1
Pages: 88-97
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Publication
28159473 | J:262103
First Author: He X
Year: 2017
Journal: Exp Cell Res
Title: Nicotinamide phosphoribosyltransferase (Nampt) may serve as the marker for osteoblast differentiation of bone marrow-derived mesenchymal stem cells.
Volume: 352
Issue: 1
Pages: 45-52
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Publication
27680548 | J:293262
 
First Author: Lin J
Year: 2016
Journal: Sci Rep
Title: Mst1 inhibits CMECs autophagy and participates in the development of diabetic coronary microvascular dysfunction.
Volume: 6
Pages: 34199
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Publication
30738214 | J:276887
 
First Author: Almeida M
Year: 2019
Journal: Bone
Title: Sirtuins and FoxOs in osteoporosis and osteoarthritis.
Volume: 121
Pages: 284-292
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Publication
30677512 | J:275552
First Author: Li S
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Fibroblast growth factor 21 protects the heart from angiotensin II-induced cardiac hypertrophy and dysfunction via SIRT1.
Volume: 1865
Issue: 6
Pages: 1241-1252
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Publication
31026620 | J:281626
 
First Author: Xiong H
Year: 2019
Journal: Neurobiol Aging
Title: Modulation of miR-34a/SIRT1 signaling protects cochlear hair cells against oxidative stress and delays age-related hearing loss through coordinated regulation of mitophagy and mitochondrial biogenesis.
Volume: 79
Pages: 30-42
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Publication
32218740 | J:288908
 
First Author: Favero G
Year: 2020
Journal: Front Physiol
Title: Sirtuin1 Role in the Melatonin Protective Effects Against Obesity-Related Heart Injury.
Volume: 11
Pages: 103
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Publication
31678070 | J:289950
 
First Author: Sim WC
Year: 2020
Journal: Metabolism
Title: Downregulation of PHGDH expression and hepatic serine level contribute to the development of fatty liver disease.
Volume: 102
Pages: 154000
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Publication
31811786 | J:297141
First Author: Yang Y
Year: 2020
Journal: Immunol Cell Biol
Title: ING4 alleviated lipopolysaccharide-induced inflammation by regulating the NF-κB pathway via a direct interaction with SIRT1.
Volume: 98
Issue: 2
Pages: 127-137
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Publication
31471557 | J:301183
First Author: Diaz-Perdigon T
Year: 2020
Journal: Neuropsychopharmacology
Title: Early sirtuin 2 inhibition prevents age-related cognitive decline in a senescence-accelerated mouse model.
Volume: 45
Issue: 2
Pages: 347-357
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Publication
32426865 | J:302049
First Author: Sun Q
Year: 2021
Journal: J Neurochem
Title: Sirtuin 3 is required for the protective effect of Resveratrol on Manganese-induced disruption of mitochondrial biogenesis in primary cultured neurons.
Volume: 156
Issue: 1
Pages: 121-135
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Publication
32509148 | J:299818
 
First Author: Zhou B
Year: 2020
Journal: Oxid Med Cell Longev
Title: FNDC5 Attenuates Oxidative Stress and NLRP3 Inflammasome Activation in Vascular Smooth Muscle Cells via Activating the AMPK-SIRT1 Signal Pathway.
Volume: 2020
Pages: 6384803
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Publication
31990656 | J:305629
First Author: Li H
Year: 2020
Journal: J Mol Endocrinol
Title: PGRN exerts inflammatory effects via SIRT1-NF-κB in adipose insulin resistance.
Volume: 64
Issue: 3
Pages: 181-193
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Publication
33069361 | J:306026
First Author: Yang Y
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Metformin ameliorates skeletal muscle atrophy in Grx1 KO mice by regulating intramuscular lipid accumulation and glucose utilization.
Volume: 533
Issue: 4
Pages: 1226-1232
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Publication
34168078 | J:343811
 
First Author: Kawasaki T
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Loss of FCHSD1 leads to amelioration of chronic obstructive pulmonary disease.
Volume: 118
Issue: 26
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Publication
30342060 | J:315634
 
First Author: Aten S
Year: 2019
Journal: Neuropharmacology
Title: miR-132/212 is induced by stress and its dysregulation triggers anxiety-related behavior.
Volume: 144
Pages: 256-270
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Publication
24688469 | J:310212
 
First Author: Cosín-Tomás M
Year: 2014
Journal: Front Aging Neurosci
Title: Epigenetic alterations in hippocampus of SAMP8 senescent mice and modulation by voluntary physical exercise.
Volume: 6
Pages: 51
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Publication
25855408 | J:310274
First Author: Zawada I
Year: 2015
Journal: Aging (Albany NY)
Title: Gene expression of key regulators of mitochondrial biogenesis is sex dependent in mice with growth hormone receptor deletion in liver.
Volume: 7
Issue: 3
Pages: 195-204
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Publication
24922076 | J:318186
 
First Author: Kim HJ
Year: 2014
Journal: Cell Death Dis
Title: Augmentation of NAD(+) by NQO1 attenuates cisplatin-mediated hearing impairment.
Volume: 5
Pages: e1292
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Publication
28963101 | J:317680
 
First Author: Piao L
Year: 2017
Journal: J Am Heart Assoc
Title: Chronic Psychological Stress Accelerates Vascular Senescence and Impairs Ischemia-Induced Neovascularization: The Role of Dipeptidyl Peptidase-4/Glucagon-Like Peptide-1-Adiponectin Axis.
Volume: 6
Issue: 10
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Publication
37399120 | J:342649
First Author: Ito J
Year: 2023
Journal: Biol Reprod
Title: Age-related advanced glycation end-product accumulation impairs mitochondrial regulation after vitrification†.
Volume: 109
Issue: 3
Pages: 271-281
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Protein
Q9Z1M6
Organism: Mus musculus/domesticus
Length: 141  
Fragment?: true
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Protein
Q9Z188
Organism: Mus musculus/domesticus
Length: 629  
Fragment?: false
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Protein
Q61214
Organism: Mus musculus/domesticus
Length: 763  
Fragment?: false
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Protein
F6U6X3
Organism: Mus musculus/domesticus
Length: 725  
Fragment?: false
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Protein
Q8K006
Organism: Mus musculus/domesticus
Length: 593  
Fragment?: true
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Protein
A9C475
Organism: Mus musculus/domesticus
Length: 763  
Fragment?: false
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Protein
Q8C774
Organism: Mus musculus/domesticus
Length: 523  
Fragment?: false
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Protein
A1L341
Organism: Mus musculus/domesticus
Length: 754  
Fragment?: false
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Publication
15965484 | -
First Author: Kustatscher G
Year: 2005
Journal: Nat Struct Mol Biol
Title: Splicing regulates NAD metabolite binding to histone macroH2A.
Volume: 12
Issue: 7
Pages: 624-5
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Publication
24717514 | J:208844
First Author: Kraus D
Year: 2014
Journal: Nature
Title: Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.
Volume: 508
Issue: 7495
Pages: 258-62
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Publication
22020252 | J:178703
First Author: Berkovits BD
Year: 2011
Journal: Dev Biol
Title: The first bromodomain of the testis-specific double bromodomain protein Brdt is required for chromocenter organization that is modulated by genetic background.
Volume: 360
Issue: 2
Pages: 358-68
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Publication
22829911 | J:189585
First Author: Xiao Y
Year: 2012
Journal: PLoS One
Title: Cre-mediated stress affects sirtuin expression levels, peroxisome biogenesis and metabolism, antioxidant and proinflammatory signaling pathways.
Volume: 7
Issue: 7
Pages: e41097
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Publication
23797704 | J:271335
First Author: Fiorentino L
Year: 2013
Journal: Acta Diabetol
Title: Regulation of TIMP3 in diabetic nephropathy: a role for microRNAs.
Volume: 50
Issue: 6
Pages: 965-9
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Publication
32863939 | J:313352
First Author: Du L
Year: 2020
Journal: Theranostics
Title: Loss of SIRT4 promotes the self-renewal of Breast Cancer Stem Cells.
Volume: 10
Issue: 21
Pages: 9458-9476
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Publication
30291911 | J:270094
 
First Author: Khadka D
Year: 2018
Journal: J Mol Cell Cardiol
Title: Augmentation of NAD+ levels by enzymatic action of NAD(P)H quinone oxidoreductase 1 attenuates adriamycin-induced cardiac dysfunction in mice.
Volume: 124
Pages: 45-57
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Publication
33569381 | J:339394
 
First Author: Gentile G
Year: 2020
Journal: Front Cell Dev Biol
Title: miRNA and mRNA Profiling Links Connexin Deficiency to Deafness via Early Oxidative Damage in the Mouse Stria Vascularis.
Volume: 8
Pages: 616878
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Publication
27500833 | J:251640
First Author: Wang X
Year: 2016
Journal: PLoS One
Title: Sirtuin-2 Regulates Sepsis Inflammation in ob/ob Mice.
Volume: 11
Issue: 8
Pages: e0160431
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Publication
31861667 | J:292304
 
First Author: Endo K
Year: 2019
Journal: Int J Mol Sci
Title: Possible Contribution of Inflammation-Associated Hypoxia to Increased K2P5.1 K+ Channel Expression in CD4+ T cells of the Mouse Model for Inflammatory Bowel Disease.
Volume: 21
Issue: 1
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Publication
27094343 | J:260650
First Author: Selsby JT
Year: 2016
Journal: J Physiol
Title: Oral quercetin administration transiently protects respiratory function in dystrophin-deficient mice.
Volume: 594
Issue: 20
Pages: 6037-6053
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Publication
21940670 | J:180633
First Author: Ljubicic V
Year: 2012
Journal: Am J Physiol Cell Physiol
Title: Chronic AMPK stimulation attenuates adaptive signaling in dystrophic skeletal muscle.
Volume: 302
Issue: 1
Pages: C110-21
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Publication
24797518 | J:214252
First Author: Brown DI
Year: 2014
Journal: PLoS One
Title: Poldip2 knockout results in perinatal lethality, reduced cellular growth and increased autophagy of mouse embryonic fibroblasts.
Volume: 9
Issue: 5
Pages: e96657
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Publication
29807366 | J:272672
First Author: Bujak M
Year: 2018
Journal: Cell Physiol Biochem
Title: Trefoil Factor 3 Deficiency Affects Liver Lipid Metabolism.
Volume: 47
Issue: 2
Pages: 827-841
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Publication
20548306 | J:273441
First Author: Froy O
Year: 2011
Journal: Int J Obes (Lond)
Title: Spontaneous caloric restriction associated with increased leptin levels in obesity-resistant αMUPA mice.
Volume: 35
Issue: 2
Pages: 226-35
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Publication
26836609 | J:259763
First Author: Duarte DA
Year: 2016
Journal: PLoS One
Title: Conditioned Medium from Early-Outgrowth Bone Marrow Cells Is Retinal Protective in Experimental Model of Diabetes.
Volume: 11
Issue: 2
Pages: e0147978
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Publication
22456698 | J:183536
First Author: Chen WL
Year: 2012
Journal: Diabetologia
Title: α-Lipoic acid regulates lipid metabolism through induction of sirtuin 1 (SIRT1) and activation of AMP-activated protein kinase.
Volume: 55
Issue: 6
Pages: 1824-35
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Publication
30359575 | J:268235
First Author: Waldman M
Year: 2018
Journal: Exp Cell Res
Title: PARP-1 inhibition protects the diabetic heart through activation of SIRT1-PGC-1α axis.
Volume: 373
Issue: 1-2
Pages: 112-118
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Publication
25875775 | J:233492
First Author: Jones HD
Year: 2015
Journal: PLoS One
Title: Nicotinamide exacerbates hypoxemia in ventilator-induced lung injury independent of neutrophil infiltration.
Volume: 10
Issue: 4
Pages: e0123460
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Publication
35959709 | J:334995
First Author: Fontana Estevez FS
Year: 2022
Journal: Cell Physiol Biochem
Title: Genetic Deletion of Galectin-3 Exacerbates Age-Related Myocardial Hypertrophy and Fibrosis in Mice.
Volume: 56
Issue: 4
Pages: 353-366
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Publication
28887652 | J:272344
First Author: Guers JJ
Year: 2017
Journal: Basic Res Cardiol
Title: Disruption of adenylyl cyclase type 5 mimics exercise training.
Volume: 112
Issue: 6
Pages: 59
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Publication
21609322 | J:175395
First Author: Caton PW
Year: 2011
Journal: Biochem J
Title: PPARα-LXR as a novel metabolostatic signalling axis in skeletal muscle that acts to optimize substrate selection in response to nutrient status.
Volume: 437
Issue: 3
Pages: 521-30
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Publication
23523784 | J:201222
First Author: Luo N
Year: 2013
Journal: Biochem Biophys Res Commun
Title: AdR1-TG/TALLYHO mice have improved lipid accumulation and insulin sensitivity.
Volume: 433
Issue: 4
Pages: 567-72
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Publication
24120971 | J:205343
 
First Author: Taheripak G
Year: 2013
Journal: Free Radic Biol Med
Title: Protein tyrosine phosphatase 1B inhibition ameliorates palmitate-induced mitochondrial dysfunction and apoptosis in skeletal muscle cells.
Volume: 65
Pages: 1435-46
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Publication
24567379 | J:207402
First Author: Cai W
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Oral glycotoxins are a modifiable cause of dementia and the metabolic syndrome in mice and humans.
Volume: 111
Issue: 13
Pages: 4940-5
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Publication
24321770 | J:210028
First Author: Huang CT
Year: 2014
Journal: Biochim Biophys Acta
Title: Energy adaptive response during parthanatos is enhanced by PD98059 and involves mitochondrial function but not autophagy induction.
Volume: 1843
Issue: 3
Pages: 531-43
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Publication
31295467 | J:282146
 
First Author: Sarkar S
Year: 2019
Journal: Brain Res
Title: Over-expression of miR-34a induces rapid cognitive impairment and Alzheimer's disease-like pathology.
Volume: 1721
Pages: 146327
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Publication
31724338 | J:295888
First Author: Kumar A
Year: 2019
Journal: Physiol Rep
Title: Alpha-calcitonin gene-related peptide prevents pressure-overload induced heart failure: role of apoptosis and oxidative stress.
Volume: 7
Issue: 21
Pages: e14269
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Publication
30556210 | J:295661
First Author: Hao S
Year: 2019
Journal: J Cell Biochem
Title: Rs1894720 polymorphism in MIAT increased susceptibility to age-related hearing loss by modulating the activation of miR-29b/SIRT1/PGC-1α signaling.
Volume: 120
Issue: 4
Pages: 4975-4986
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Publication
32259637 | J:296873
 
First Author: Santos FO
Year: 2020
Journal: Mol Cell Endocrinol
Title: Anti-steatotic linagliptin pleiotropic effects encompasses suppression of de novo lipogenesis and ER stress in high-fat-fed mice.
Volume: 509
Pages: 110804
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Publication
31632286 | J:313108
 
First Author: Wang X
Year: 2019
Journal: Front Physiol
Title: QiDiTangShen Granules Activate Renal Nutrient-Sensing Associated Autophagy in db/db Mice.
Volume: 10
Pages: 1224
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Publication
35096807 | J:319719
 
First Author: Cuomo F
Year: 2021
Journal: Front Cell Dev Biol
Title: HIF3A Inhibition Triggers Browning of White Adipocytes via Metabolic Rewiring.
Volume: 9
Pages: 740203
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Protein
Q8CCK0
Organism: Mus musculus/domesticus
Length: 372  
Fragment?: false
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Protein
Q9QZQ8
Organism: Mus musculus/domesticus
Length: 372  
Fragment?: false
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Protein
Q8CH18
Organism: Mus musculus/domesticus
Length: 1146  
Fragment?: false
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Publication
37730113 | J:342071
 
First Author: Wang ZJ
Year: 2023
Journal: Neuropharmacology
Title: Semaglutide ameliorates cognition and glucose metabolism dysfunction in the 3xTg mouse model of Alzheimer's disease via the GLP-1R/SIRT1/GLUT4 pathway.
Volume: 240
Pages: 109716
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Publication
31347918 | J:280087
First Author: Byun J
Year: 2019
Journal: Am J Physiol Heart Circ Physiol
Title: Both gain and loss of Nampt function promote pressure overload-induced heart failure.
Volume: 317
Issue: 4
Pages: H711-H725
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Publication
32292498 | J:302408
First Author: Shen G
Year: 2020
Journal: Theranostics
Title: miR-128 plays a critical role in murine osteoclastogenesis and estrogen deficiency-induced bone loss.
Volume: 10
Issue: 10
Pages: 4334-4348
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Protein
H3BJ41
Organism: Mus musculus/domesticus
Length: 52  
Fragment?: false
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Protein
E0CZH5
Organism: Mus musculus/domesticus
Length: 90  
Fragment?: true
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Protein
Q3UYT2
Organism: Mus musculus/domesticus
Length: 385  
Fragment?: true
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Protein
Q61158
Organism: Mus musculus/domesticus
Length: 87  
Fragment?: true
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Publication
12383504 | J:79579
First Author: Su HL
Year: 2002
Journal: Gene
Title: Molecular features of human ubiquitin-like SUMO genes and their encoded proteins.
Volume: 296
Issue: 1-2
Pages: 65-73
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Protein
Q9R1Y5
Organism: Mus musculus/domesticus
Length: 733  
Fragment?: false
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•
•
•
Protein
Z4YJP0
Organism: Mus musculus/domesticus
Length: 714  
Fragment?: false
•
•
•
•
•
Protein
A0PJB8
Organism: Mus musculus/domesticus
Length: 192  
Fragment?: true
•
•
•
•
•
Publication
15902274 | -
First Author: Karras GI
Year: 2005
Journal: EMBO J
Title: The macro domain is an ADP-ribose binding module.
Volume: 24
Issue: 11
Pages: 1911-20
•
•
•
•
•
Publication
30209975 | J:329573
First Author: Yau WW
Year: 2019
Journal: Autophagy
Title: Thyroid hormone (T3) stimulates brown adipose tissue activation via mitochondrial biogenesis and MTOR-mediated mitophagy.
Volume: 15
Issue: 1
Pages: 131-150
•
•
•
•
•
Protein
O54714
Organism: Mus musculus/domesticus
Length: 628  
Fragment?: false
•
•
•
•
•
Protein
Q8BP16
Organism: Mus musculus/domesticus
Length: 356  
Fragment?: false
•
•
•
•
•
Protein
Q9D3V6
Organism: Mus musculus/domesticus
Length: 382  
Fragment?: false
•
•
•
•
•
Protein
E0CZ31
Organism: Mus musculus/domesticus
Length: 430  
Fragment?: false
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•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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