Brain mitochondrial carrier protein 1 (SLC25A14, also known as UCP5) is a member of the SLC25 family. UCP5 may be involved in tissue-specific thermoregulation and metabolic changes associated with nutritional status []. Overexpression of UCP5 resulted in reduced mitochondrial membrane potential (MMP), reduced intracellular ATP content, and reduced levels of ROS [].Mitochondrial solute carrier 25 (SLC25) family proteins function as transporters of a large variety of molecules, including ATP, ADP and amino acids [].
