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Search results 1701 to 1800 out of 2322 for Erbb2

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Hits by Pathway

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Hits by Category

Type Details Score
Genotype
Symbol: Ccnd1/Ccnd1 Tg(MMTVneu)202Mul/? Tg(tetO-Ccnd1*T286A,-luc)11233Kuw/?
Background: involves: 129S2/SvPas * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Ccnd1/Ccnd1 Tg(MMTVneu)202Mul/? Tg(tetO-Ccnd1*T286A,-luc)10897Kuw/?
Background: involves: 129S2/SvPas * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Ccnd1/Ccnd1 Tg(MMTVneu)202Mul/?
Background: involves: 129S2/SvPas * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(MMTV-ERBB2*)#Arbs/?
Background: FVB-Tg(MMTV-ERBB2*)#Arbs
Zygosity: ot
Has Mutant Allele: true
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 481  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 189  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 189  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 189  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1068  
Fragment?: false
Publication
First Author: Sukhanova A
Year: 2013
Journal: Cancer Discov
Title: Targeting C4-demethylating genes in the cholesterol pathway sensitizes cancer cells to EGF receptor inhibitors via increased EGF receptor degradation.
Volume: 3
Issue: 1
Pages: 96-111
Publication
First Author: Porzia A
Year: 2010
Journal: J Immunol
Title: Attenuation of PI3K/Akt-mediated tumorigenic signals through PTEN activation by DNA vaccine-induced anti-ErbB2 antibodies.
Volume: 184
Issue: 8
Pages: 4170-7
Publication
First Author: Yang C
Year: 2004
Journal: Am J Pathol
Title: The role of the cyclin D1-dependent kinases in ErbB2-mediated breast cancer.
Volume: 164
Issue: 3
Pages: 1031-8
Publication  
First Author: Le TL
Year: 2021
Journal: J Clin Invest
Title: Dysregulation of the NRG1/ERBB pathway causes a developmental disorder with gastrointestinal dysmotility in humans.
Volume: 131
Issue: 6
Publication
First Author: Sinha VC
Year: 2015
Journal: Mol Cancer Res
Title: A p53/ARF-dependent anticancer barrier activates senescence and blocks tumorigenesis without impacting apoptosis.
Volume: 13
Issue: 2
Pages: 231-8
Publication
First Author: Lee D
Year: 2009
Journal: J Clin Invest
Title: Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium.
Volume: 119
Issue: 9
Pages: 2702-13
Publication
First Author: Song X
Year: 2015
Journal: Cancer Res
Title: ERBB3-independent activation of the PI3K pathway in EGFR-mutant lung adenocarcinomas.
Volume: 75
Issue: 6
Pages: 1035-45
Publication
First Author: Yoshioka T
Year: 2013
Journal: J Clin Invest
Title: β4 Integrin signaling induces expansion of prostate tumor progenitors.
Volume: 123
Issue: 2
Pages: 682-99
Publication
First Author: Liu FF
Year: 2005
Journal: Am J Physiol Heart Circ Physiol
Title: Heterozygous knockout of neuregulin-1 gene in mice exacerbates doxorubicin-induced heart failure.
Volume: 289
Issue: 2
Pages: H660-6
Publication
First Author: Seshadri S
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade.
Volume: 107
Issue: 12
Pages: 5622-7
Publication
First Author: Limpert AS
Year: 2010
Journal: J Biol Chem
Title: Axonal neuregulin 1 type III activates NF-kappaB in Schwann cells during myelin formation.
Volume: 285
Issue: 22
Pages: 16614-22
Publication
First Author: Cook RS
Year: 2011
Journal: Cancer Res
Title: ErbB3 ablation impairs PI3K/Akt-dependent mammary tumorigenesis.
Volume: 71
Issue: 11
Pages: 3941-51
Publication
First Author: Usui M
Year: 2002
Journal: J Bone Miner Res
Title: Enhancing effect of Tob deficiency on bone formation is specific to bone morphogenetic protein-induced osteogenesis.
Volume: 17
Issue: 6
Pages: 1026-33
Publication
First Author: Schmucker J
Year: 2003
Journal: Glia
Title: erbB3 is dispensable for oligodendrocyte development in vitro and in vivo.
Volume: 44
Issue: 1
Pages: 67-75
Publication
First Author: Ghidinelli M
Year: 2017
Journal: PLoS Biol
Title: Laminin 211 inhibits protein kinase A in Schwann cells to modulate neuregulin 1 type III-driven myelination.
Volume: 15
Issue: 6
Pages: e2001408
Publication
First Author: Huebner RJ
Year: 2014
Journal: Development
Title: Developmental stratification of the mammary epithelium occurs through symmetry-breaking vertical divisions of apically positioned luminal cells.
Volume: 141
Issue: 5
Pages: 1085-94
Publication  
First Author: Ueda O
Year: 2017
Journal: Sci Rep
Title: Entire CD3ε, δ, and γ humanized mouse to evaluate human CD3-mediated therapeutics.
Volume: 7
Pages: 45839
Publication
First Author: Dahlhoff M
Year: 2013
Journal: Biochim Biophys Acta
Title: Increased activation of the epidermal growth factor receptor in transgenic mice overexpressing epigen causes peripheral neuropathy.
Volume: 1832
Issue: 12
Pages: 2068-76
Publication
First Author: Cicchini M
Year: 2014
Journal: Autophagy
Title: Autophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity.
Volume: 10
Issue: 11
Pages: 2036-52
Publication
First Author: Hoesl C
Year: 2018
Journal: Biochim Biophys Acta
Title: The receptor tyrosine kinase ERBB4 is expressed in skin keratinocytes and influences epidermal proliferation.
Volume: 1862
Issue: 4
Pages: 958-966
Publication
First Author: Kuns R
Year: 2005
Journal: Oncogene
Title: Protein 4.1B expression is induced in mammary epithelial cells during pregnancy and regulates their proliferation.
Volume: 24
Issue: 43
Pages: 6502-15
Publication
First Author: Stankovic K
Year: 2004
Journal: J Neurosci
Title: Survival of adult spiral ganglion neurons requires erbB receptor signaling in the inner ear.
Volume: 24
Issue: 40
Pages: 8651-61
Publication
First Author: Tao Y
Year: 2016
Journal: Carcinogenesis
Title: Hsp70 exerts oncogenic activity in the Apc mutant Min mouse model.
Volume: 37
Issue: 7
Pages: 731-739
Publication
First Author: Ruan YC
Year: 2014
Journal: J Cell Sci
Title: CFTR interacts with ZO-1 to regulate tight junction assembly and epithelial differentiation through the ZONAB pathway.
Volume: 127
Issue: Pt 20
Pages: 4396-408
Publication
First Author: Vandekerckhove L
Year: 2016
Journal: Am J Physiol Endocrinol Metab
Title: Neuregulin-1 attenuates development of nephropathy in a type 1 diabetes mouse model with high cardiovascular risk.
Volume: 310
Issue: 7
Pages: E495-504
Publication
First Author: Liu J
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Trichostatin A suppresses lung adenocarcinoma development in Grg1 overexpressing transgenic mice.
Volume: 463
Issue: 4
Pages: 1230-6
Publication
First Author: Logan AM
Year: 2017
Journal: Glia
Title: Schwann cell-specific deletion of the endosomal PI 3-kinase Vps34 leads to delayed radial sorting of axons, arrested myelination, and abnormal ErbB2-ErbB3 tyrosine kinase signaling.
Volume: 65
Issue: 9
Pages: 1452-1470
Publication
First Author: Cadieux C
Year: 2009
Journal: Cancer Res
Title: Mouse mammary tumor virus p75 and p110 CUX1 transgenic mice develop mammary tumors of various histologic types.
Volume: 69
Issue: 18
Pages: 7188-97
Publication
First Author: Young CD
Year: 2011
Journal: PLoS One
Title: Modulation of glucose transporter 1 (GLUT1) expression levels alters mouse mammary tumor cell growth in vitro and in vivo.
Volume: 6
Issue: 8
Pages: e23205
Publication
First Author: Lemmens K
Year: 2011
Journal: Am J Physiol Heart Circ Physiol
Title: Activation of the neuregulin/ErbB system during physiological ventricular remodeling in pregnancy.
Volume: 300
Issue: 3
Pages: H931-42
Publication
First Author: Jo SA
Year: 1995
Journal: Nature
Title: Neuregulins are concentrated at nerve-muscle synapses and activate ACh-receptor gene expression.
Volume: 373
Issue: 6510
Pages: 158-61
Publication
First Author: Bafico A
Year: 1998
Journal: Oncogene
Title: Characterization of Wnt-1 and Wnt-2 induced growth alterations and signaling pathways in NIH3T3 fibroblasts.
Volume: 16
Issue: 21
Pages: 2819-25
Publication
First Author: Wagner M
Year: 2002
Journal: Gastroenterology
Title: Transgenic overexpression of amphiregulin induces a mitogenic response selectively in pancreatic duct cells.
Volume: 122
Issue: 7
Pages: 1898-912
Publication
First Author: Yang C
Year: 2006
Journal: Cancer Res
Title: Identification of cyclin D1- and estrogen-regulated genes contributing to breast carcinogenesis and progression.
Volume: 66
Issue: 24
Pages: 11649-58
Publication
First Author: Wu Q
Year: 2007
Journal: Cancer Res
Title: Therapeutic effect of rapamycin on gallbladder cancer in a transgenic mouse model.
Volume: 67
Issue: 8
Pages: 3794-800
Publication
First Author: Barrick CJ
Year: 2008
Journal: Toxicol Appl Pharmacol
Title: Chronic pharmacologic inhibition of EGFR leads to cardiac dysfunction in C57BL/6J mice.
Volume: 228
Issue: 3
Pages: 315-25
Publication
First Author: Fehrenbacher N
Year: 2008
Journal: Cancer Res
Title: Sensitization to the lysosomal cell death pathway by oncogene-induced down-regulation of lysosome-associated membrane proteins 1 and 2.
Volume: 68
Issue: 16
Pages: 6623-33
Publication
First Author: Liu M
Year: 2009
Journal: Am J Pathol
Title: Nuclear factor-kappaB enhances ErbB2-induced mammary tumorigenesis and neoangiogenesis in vivo.
Volume: 174
Issue: 5
Pages: 1910-20
Publication
First Author: Ingalla EQ
Year: 2010
Journal: J Biol Chem
Title: Post-transcriptional mechanisms contribute to the suppression of the ErbB3 negative regulator protein Nrdp1 in mammary tumors.
Volume: 285
Issue: 37
Pages: 28691-7
Publication
First Author: Liu M
Year: 2010
Journal: Cancer Res
Title: The canonical NF-kappaB pathway governs mammary tumorigenesis in transgenic mice and tumor stem cell expansion.
Volume: 70
Issue: 24
Pages: 10464-73
Publication
First Author: Liu Y
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Neuregulin 1-β regulates cell adhesion molecule L1 expression in the cortex and hippocampus of mice.
Volume: 441
Issue: 1
Pages: 7-12
Publication
First Author: Haricharan S
Year: 2014
Journal: Oncogene
Title: Contribution of an alveolar cell of origin to the high-grade malignant phenotype of pregnancy-associated breast cancer.
Volume: 33
Issue: 50
Pages: 5729-39
Publication
First Author: Torii T
Year: 2014
Journal: Biochem Biophys Res Commun
Title: In vivo knockdown of ErbB3 in mice inhibits Schwann cell precursor migration.
Volume: 452
Issue: 3
Pages: 782-8
Publication
First Author: Memmi EM
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: p63 Sustains self-renewal of mammary cancer stem cells through regulation of Sonic Hedgehog signaling.
Volume: 112
Issue: 11
Pages: 3499-504
Publication
First Author: Boulay PL
Year: 2016
Journal: Cancer Res
Title: Rab11-FIP1C Is a Critical Negative Regulator in ErbB2-Mediated Mammary Tumor Progression.
Volume: 76
Issue: 9
Pages: 2662-74
Publication
First Author: Yang L
Year: 2016
Journal: Am J Hum Genet
Title: Analyzing Somatic Genome Rearrangements in Human Cancers by Using Whole-Exome Sequencing.
Volume: 98
Issue: 5
Pages: 843-856
Publication
First Author: Horiuchi D
Year: 2016
Journal: Nat Med
Title: PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression.
Volume: 22
Issue: 11
Pages: 1321-1329
Publication
First Author: Alizadeh A
Year: 2017
Journal: Glia
Title: Neuregulin-1 positively modulates glial response and improves neurological recovery following traumatic spinal cord injury.
Volume: 65
Issue: 7
Pages: 1152-1175
Publication
First Author: Simonis A
Year: 2014
Journal: PLoS Pathog
Title: Differential activation of acid sphingomyelinase and ceramide release determines invasiveness of Neisseria meningitidis into brain endothelial cells.
Volume: 10
Issue: 6
Pages: e1004160
Publication
First Author: Gupta MK
Year: 2021
Journal: Sci Rep
Title: Cardiac expression of microRNA-7 is associated with adverse cardiac remodeling.
Volume: 11
Issue: 1
Pages: 22018
Publication
First Author: Andrade-Vieira R
Year: 2014
Journal: Oncotarget
Title: Pre-clinical study of drug combinations that reduce breast cancer burden due to aberrant mTOR and metabolism promoted by LKB1 loss.
Volume: 5
Issue: 24
Pages: 12738-52
Publication
First Author: Lyu H
Year: 2015
Journal: Int J Clin Exp Pathol
Title: Increased erbB3 promotes erbB2/neu-driven mammary tumor proliferation and co-targeting of erbB2/erbB3 receptors exhibits potent inhibitory effects on breast cancer cells.
Volume: 8
Issue: 6
Pages: 6143-56
Publication  
First Author: Purazo ML
Year: 2023
Journal: Cancers (Basel)
Title: NEDD9 Overexpression Causes Hyperproliferation of Luminal Cells and Cooperates with HER2 Oncogene in Tumor Initiation: A Novel Prognostic Marker in Breast Cancer.
Volume: 15
Issue: 4
Publication
First Author: Macdonald-Obermann JL
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Mechanics of EGF receptor/ErbB2 kinase activation revealed by luciferase fragment complementation imaging.
Volume: 109
Issue: 1
Pages: 137-42
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory