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Search results 1 to 100 out of 223 for Lrp2

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Category: Publication
Type Details Score
Publication
First Author: Oh SJ
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Progesterone induces expression of Lrp2 in the murine uterus.
Volume: 441
Issue: 1
Pages: 175-9
Publication
First Author: Kur E
Year: 2014
Journal: J Cell Sci
Title: LRP2 mediates folate uptake in the developing neural tube.
Volume: 127
Issue: Pt 10
Pages: 2261-8
Publication
First Author: Christ A
Year: 2012
Journal: Dev Cell
Title: LRP2 is an auxiliary SHH receptor required to condition the forebrain ventral midline for inductive signals.
Volume: 22
Issue: 2
Pages: 268-78
Publication
First Author: Baardman ME
Year: 2016
Journal: Dis Model Mech
Title: Common arterial trunk and ventricular non-compaction in Lrp2 knockout mice indicate a crucial role of LRP2 in cardiac development.
Volume: 9
Issue: 4
Pages: 413-25
Publication
First Author: Gajera CR
Year: 2010
Journal: J Cell Sci
Title: LRP2 in ependymal cells regulates BMP signaling in the adult neurogenic niche.
Volume: 123
Issue: Pt 11
Pages: 1922-30
Publication  
First Author: Mai S
Year: 2022
Journal: Development
Title: Postnatal eye size in mice is controlled by SREBP2-mediated transcriptional repression of Lrp2 and Bmp2.
Volume: 149
Issue: 14
Publication
First Author: Gerbe F
Year: 2008
Journal: Dev Biol
Title: Dynamic expression of Lrp2 pathway members reveals progressive epithelial differentiation of primitive endoderm in mouse blastocyst.
Volume: 313
Issue: 2
Pages: 594-602
Publication
First Author: Christ A
Year: 2015
Journal: Dev Cell
Title: LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli.
Volume: 35
Issue: 1
Pages: 36-48
Publication  
First Author: Kowalczyk I
Year: 2021
Journal: Development
Title: Neural tube closure requires the endocytic receptor Lrp2 and its functional interaction with intracellular scaffolds.
Volume: 148
Issue: 2
Publication
First Author: Christ A
Year: 2020
Journal: Hum Mol Genet
Title: LRP2 controls sonic hedgehog-dependent differentiation of cardiac progenitor cells during outflow tract formation.
Volume: 29
Issue: 19
Pages: 3183-3196
Publication
First Author: Cases O
Year: 2015
Journal: PLoS One
Title: Foxg1-Cre Mediated Lrp2 Inactivation in the Developing Mouse Neural Retina, Ciliary and Retinal Pigment Epithelia Models Congenital High Myopia.
Volume: 10
Issue: 6
Pages: e0129518
Publication    
First Author: Hammad SM
Year: 2000
Journal: GenBank Submission
Title: Mus musculus low density lipoprotein receptor-related protein 2 LRP2 (Lrp2) mRNA, partial cds
Pages: AF197160
Publication
First Author: Petersen HH
Year: 2003
Journal: J Cell Sci
Title: Functional interaction of megalin with the megalinbinding protein (MegBP), a novel tetratrico peptide repeat-containing adaptor molecule.
Volume: 116
Issue: Pt 3
Pages: 453-61
Publication
First Author: Christ A
Year: 2010
Journal: Kidney Int
Title: The soluble intracellular domain of megalin does not affect renal proximal tubular function in vivo.
Volume: 78
Issue: 5
Pages: 473-7
Publication
First Author: Storm T
Year: 2019
Journal: Invest Ophthalmol Vis Sci
Title: Selective Ablation of Megalin in the Retinal Pigment Epithelium Results in Megaophthalmos, Macromelanosome Formation and Severe Retina Degeneration.
Volume: 60
Issue: 1
Pages: 322-330
Publication
First Author: Cases O
Year: 2017
Journal: Biochim Biophys Acta
Title: Impaired vitreous composition and retinal pigment epithelium function in the FoxG1::LRP2 myopic mice.
Volume: 1863
Issue: 6
Pages: 1242-1254
Publication
First Author: Charlton JR
Year: 2020
Journal: Am J Physiol Renal Physiol
Title: Beyond the tubule: pathological variants of LRP2, encoding the megalin receptor, result in glomerular loss and early progressive chronic kidney disease.
Volume: 319
Issue: 6
Pages: F988-F999
Publication
First Author: Long KR
Year: 2022
Journal: Am J Physiol Renal Physiol
Title: Cubilin-, megalin-, and Dab2-dependent transcription revealed by CRISPR/Cas9 knockout in kidney proximal tubule cells.
Volume: 322
Issue: 1
Pages: F14-F26
Publication
First Author: Lighthouse JK
Year: 2011
Journal: Dev Dyn
Title: MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.
Volume: 240
Issue: 3
Pages: 577-88
Publication  
First Author: Shen TH
Year: 2022
Journal: JCI Insight
Title: Snapshots of nascent RNA reveal cell- and stimulus-specific responses to acute kidney injury.
Volume: 7
Issue: 6
Publication
First Author: Nykjaer A
Year: 1999
Journal: Cell
Title: An endocytic pathway essential for renal uptake and activation of the steroid 25-(OH) vitamin D3.
Volume: 96
Issue: 4
Pages: 507-15
Publication
First Author: Gburek J
Year: 2003
Journal: Am J Physiol Renal Physiol
Title: Renal uptake of myoglobin is mediated by the endocytic receptors megalin and cubilin.
Volume: 285
Issue: 3
Pages: F451-8
Publication
First Author: Hammes A
Year: 2005
Journal: Cell
Title: Role of endocytosis in cellular uptake of sex steroids.
Volume: 122
Issue: 5
Pages: 751-62
Publication
First Author: Gonzalez-Villalobos R
Year: 2006
Journal: Am J Physiol Renal Physiol
Title: Megalin binds and internalizes angiotensin-(1-7).
Volume: 290
Issue: 5
Pages: F1270-5
Publication
First Author: König O
Year: 2008
Journal: FASEB J
Title: Estrogen and the inner ear: megalin knockout mice suffer progressive hearing loss.
Volume: 22
Issue: 2
Pages: 410-7
Publication
First Author: Dietrich M
Year: 2014
Journal: J Alzheimers Dis
Title: Alzheimer's disease-like impaired cognition in endothelial-specific megalin-null mice.
Volume: 39
Issue: 4
Pages: 711-7
Publication
First Author: Dietrich MO
Year: 2008
Journal: Neurobiol Aging
Title: Megalin mediates the transport of leptin across the blood-CSF barrier.
Volume: 29
Issue: 6
Pages: 902-12
Publication
First Author: Leheste JR
Year: 2003
Journal: FASEB J
Title: Hypocalcemia and osteopathy in mice with kidney-specific megalin gene defect.
Volume: 17
Issue: 2
Pages: 247-9
Publication
First Author: Bachmann S
Year: 2004
Journal: J Am Soc Nephrol
Title: Kidney-specific inactivation of the megalin gene impairs trafficking of renal inorganic sodium phosphate cotransporter (NaPi-IIa).
Volume: 15
Issue: 4
Pages: 892-900
Publication
First Author: Theilig F
Year: 2007
Journal: J Am Soc Nephrol
Title: Abrogation of protein uptake through megalin-deficient proximal tubules does not safeguard against tubulointerstitial injury.
Volume: 18
Issue: 6
Pages: 1824-34
Publication
First Author: Kuwahara S
Year: 2016
Journal: J Am Soc Nephrol
Title: Megalin-Mediated Tubuloglomerular Alterations in High-Fat Diet-Induced Kidney Disease.
Volume: 27
Issue: 7
Pages: 1996-2008
Publication
First Author: Raila J
Year: 2005
Journal: J Nutr
Title: Megalin-mediated reuptake of retinol in the kidneys of mice is essential for vitamin A homeostasis.
Volume: 135
Issue: 11
Pages: 2512-6
Publication
First Author: Motoyoshi Y
Year: 2008
Journal: Kidney Int
Title: Megalin contributes to the early injury of proximal tubule cells during nonselective proteinuria.
Volume: 74
Issue: 10
Pages: 1262-9
Publication
First Author: Bartolome F
Year: 2017
Journal: J Neuroinflammation
Title: Obesity and neuroinflammatory phenotype in mice lacking endothelial megalin.
Volume: 14
Issue: 1
Pages: 26
Publication
First Author: Bartolome F
Year: 2020
Journal: J Neuroinflammation
Title: Endothelial-specific deficiency of megalin in the brain protects mice against high-fat diet challenge.
Volume: 17
Issue: 1
Pages: 22
Publication
First Author: Willnow TE
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Defective forebrain development in mice lacking gp330/megalin.
Volume: 93
Issue: 16
Pages: 8460-4
Publication
First Author: Zywitza V
Year: 2018
Journal: Cell Rep
Title: Single-Cell Transcriptomics Characterizes Cell Types in the Subventricular Zone and Uncovers Molecular Defects Impairing Adult Neurogenesis.
Volume: 25
Issue: 9
Pages: 2457-2469.e8
Publication
First Author: Moestrup SK
Year: 1998
Journal: J Clin Invest
Title: beta2-glycoprotein-I (apolipoprotein H) and beta2-glycoprotein-I-phospholipid complex harbor a recognition site for the endocytic receptor megalin.
Volume: 102
Issue: 5
Pages: 902-9
Publication
First Author: Vohwinkel CU
Year: 2017
Journal: Am J Respir Cell Mol Biol
Title: Restoration of Megalin-Mediated Clearance of Alveolar Protein as a Novel Therapeutic Approach for Acute Lung Injury.
Volume: 57
Issue: 5
Pages: 589-602
Publication
First Author: Birn H
Year: 2000
Journal: J Clin Invest
Title: Cubilin is an albumin binding protein important for renal tubular albumin reabsorption.
Volume: 105
Issue: 10
Pages: 1353-61
Publication
First Author: Birn H
Year: 2002
Journal: Am J Physiol Renal Physiol
Title: Megalin is essential for renal proximal tubule reabsorption and accumulation of transcobalamin-B(12).
Volume: 282
Issue: 3
Pages: F408-16
Publication
First Author: Leheste JR
Year: 1999
Journal: Am J Pathol
Title: Megalin knockout mice as an animal model of low molecular weight proteinuria.
Volume: 155
Issue: 4
Pages: 1361-70
Publication
First Author: Christensen EI
Year: 1999
Journal: J Am Soc Nephrol
Title: Evidence for an essential role of megalin in transepithelial transport of retinol.
Volume: 10
Issue: 4
Pages: 685-95
Publication
First Author: Leshchiner I
Year: 2012
Journal: Genome Res
Title: Mutation mapping and identification by whole-genome sequencing.
Volume: 22
Issue: 8
Pages: 1541-8
Publication
First Author: Lisi S
Year: 2005
Journal: Mol Cell Endocrinol
Title: Thyroid dysfunction in megalin deficient mice.
Volume: 236
Issue: 1-2
Pages: 43-7
Publication
First Author: Chiu-Ugalde J
Year: 2010
Journal: Biochem J
Title: Mutation of megalin leads to urinary loss of selenoprotein P and selenium deficiency in serum, liver, kidneys and brain.
Volume: 431
Issue: 1
Pages: 103-11
Publication
First Author: Gueth-Hallonet C
Year: 1994
Journal: Development
Title: Gp330 is specifically expressed in outer cells during epithelial differentiation in the preimplantation mouse embryo.
Volume: 120
Issue: 11
Pages: 3289-99
Publication
First Author: Chowdhary BP
Year: 1995
Journal: Cytogenet Cell Genet
Title: In situ hybridization mapping of a 500-kDa calcium-sensing protein gene (LRP2) to human chromosome region 2q31-->q32.1 and porcine chromosome region 15q22-->q24.
Volume: 71
Issue: 2
Pages: 120-3
Publication
First Author: Niemeier A
Year: 1999
Journal: Arterioscler Thromb Vasc Biol
Title: Identification of megalin/gp330 as a receptor for lipoprotein(a) in vitro.
Volume: 19
Issue: 3
Pages: 552-61
Publication
First Author: De S
Year: 2017
Journal: Diabetes
Title: Exocytosis-Mediated Urinary Full-Length Megalin Excretion Is Linked With the Pathogenesis of Diabetic Nephropathy.
Volume: 66
Issue: 5
Pages: 1391-1404
Publication
First Author: Hammad SM
Year: 2000
Journal: J Biol Chem
Title: Megalin acts in concert with cubilin to mediate endocytosis of high density lipoproteins.
Volume: 275
Issue: 16
Pages: 12003-8
Publication
First Author: Drake CJ
Year: 2004
Journal: Anat Rec A Discov Mol Cell Evol Biol
Title: Differential distribution of cubilin and megalin expression in the mouse embryo.
Volume: 277
Issue: 1
Pages: 163-70
Publication
First Author: Assémat E
Year: 2005
Journal: Biol Reprod
Title: Expression and role of cubilin in the internalization of nutrients during the peri-implantation development of the rodent embryo.
Volume: 72
Issue: 5
Pages: 1079-86
Publication
First Author: Faber K
Year: 2006
Journal: Mol Endocrinol
Title: Megalin is a receptor for apolipoprotein M, and kidney-specific megalin-deficiency confers urinary excretion of apolipoprotein M.
Volume: 20
Issue: 1
Pages: 212-8
Publication
First Author: Kaseda R
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Megalin-mediated endocytosis of cystatin C in proximal tubule cells.
Volume: 357
Issue: 4
Pages: 1130-4
Publication
First Author: Jobst-Schwan T
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Renal uptake of the antiapoptotic protein survivin is mediated by megalin at the apical membrane of the proximal tubule.
Volume: 305
Issue: 5
Pages: F734-44
Publication
First Author: Hirano M
Year: 2017
Journal: Biochim Biophys Acta
Title: N-Glycoform-dependent interactions of megalin with its ligands.
Volume: 1861
Issue: 1 Pt A
Pages: 3106-3118
Publication
First Author: Johanns M
Year: 2017
Journal: Sci Rep
Title: Cellular uptake of proMMP-2:TIMP-2 complexes by the endocytic receptor megalin/LRP-2.
Volume: 7
Issue: 1
Pages: 4328
Publication
First Author: Arora K
Year: 2017
Journal: FASEB J
Title: Maternofetal transport of vitamin B12: role of TCblR/CD320 and megalin.
Volume: 31
Issue: 7
Pages: 3098-3106
Publication
First Author: Lai SC
Year: 2013
Journal: FASEB J
Title: The transcobalamin receptor knockout mouse: a model for vitamin B12 deficiency in the central nervous system.
Volume: 27
Issue: 6
Pages: 2468-75
Publication
First Author: Nielsen R
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells.
Volume: 104
Issue: 13
Pages: 5407-12
Publication
First Author: Fleming CE
Year: 2009
Journal: J Neurosci
Title: Transthyretin internalization by sensory neurons is megalin mediated and necessary for its neuritogenic activity.
Volume: 29
Issue: 10
Pages: 3220-32
Publication
First Author: Storm T
Year: 2014
Journal: Cell Tissue Res
Title: Megalin-deficiency causes high myopia, retinal pigment epithelium-macromelanosomes and abnormal development of the ciliary body in mice.
Volume: 358
Issue: 1
Pages: 99-107
Publication  
First Author: Barasch J
Year: 2016
Journal: Nat Commun
Title: Disposal of iron by a mutant form of lipocalin 2.
Volume: 7
Pages: 12973
Publication
First Author: Bouchard G
Year: 1999
Journal: Mamm Genome
Title: High-resolution maps of the murine Chromosome 2 region containing the cholesterol gallstone locus, Lith1.
Volume: 10
Issue: 11
Pages: 1070-4
Publication
First Author: Moll S
Year: 1998
Journal: Am J Pathol
Title: Tubular up-regulation of clusterin mRNA in murine lupus-like nephritis.
Volume: 152
Issue: 4
Pages: 953-62
Publication
First Author: Birn H
Year: 2000
Journal: J Am Soc Nephrol
Title: Receptor-associated protein is important for normal processing of megalin in kidney proximal tubules.
Volume: 11
Issue: 2
Pages: 191-202
Publication
First Author: Zhang H
Year: 2008
Journal: Biochim Biophys Acta
Title: Core 2 GlcNAc modification and megalin ligand-binding activity.
Volume: 1780
Issue: 3
Pages: 479-85
Publication
First Author: Strope S
Year: 2004
Journal: Development
Title: Mouse amnionless, which is required for primitive streak assembly, mediates cell-surface localization and endocytic function of cubilin on visceral endoderm and kidney proximal tubules.
Volume: 131
Issue: 19
Pages: 4787-95
Publication
First Author: Olson GE
Year: 2008
Journal: J Biol Chem
Title: Megalin mediates selenoprotein P uptake by kidney proximal tubule epithelial cells.
Volume: 283
Issue: 11
Pages: 6854-60
Publication
First Author: Follit JA
Year: 2010
Journal: J Cell Biol
Title: The cytoplasmic tail of fibrocystin contains a ciliary targeting sequence.
Volume: 188
Issue: 1
Pages: 21-8
Publication
First Author: van Hoek AN
Year: 2000
Journal: Am J Physiol Renal Physiol
Title: Aquaporin-4 is expressed in basolateral membranes of proximal tubule S3 segments in mouse kidney.
Volume: 278
Issue: 2
Pages: F310-6
Publication  
First Author: Gelineau-van Waes J
Year: 2008
Journal: BMC Genomics
Title: Microarray analysis of E9.5 reduced folate carrier (RFC1; Slc19a1) knockout embryos reveals altered expression of genes in the cubilin-megalin multiligand endocytic receptor complex.
Volume: 9
Pages: 156
Publication
First Author: Pohl M
Year: 2015
Journal: J Am Soc Nephrol
Title: Short-term functional adaptation of aquaporin-1 surface expression in the proximal tubule, a component of glomerulotubular balance.
Volume: 26
Issue: 6
Pages: 1269-78
Publication
First Author: Nagai J
Year: 2005
Journal: Am J Physiol Renal Physiol
Title: Mutually dependent localization of megalin and Dab2 in the renal proximal tubule.
Volume: 289
Issue: 3
Pages: F569-76
Publication
First Author: Ren Q
Year: 2020
Journal: Am J Physiol Renal Physiol
Title: Distinct functions of megalin and cubilin receptors in recovery of normal and nephrotic levels of filtered albumin.
Volume: 318
Issue: 5
Pages: F1284-F1294
Publication
First Author: Gomes JR
Year: 2016
Journal: Cell Death Differ
Title: Transthyretin provides trophic support via megalin by promoting neurite outgrowth and neuroprotection in cerebral ischemia.
Volume: 23
Issue: 11
Pages: 1749-1764
Publication  
First Author: Liang S
Year: 2023
Journal: Front Cell Dev Biol
Title: Generation and characterization of an inducible renal proximal tubule-specific CreERT2 mouse.
Volume: 11
Pages: 1171637
Publication
First Author: Kawakami R
Year: 2021
Journal: J Pathol
Title: Urinary FABP1 is a biomarker for impaired proximal tubular protein reabsorption and is synergistically enhanced by concurrent liver injury.
Volume: 255
Issue: 4
Pages: 362-373
Publication  
First Author: Otomo H
Year: 2020
Journal: Metabolism
Title: Sodium-glucose cotransporter 2 inhibition attenuates protein overload in renal proximal tubule via suppression of megalin O-GlcNacylation in progressive diabetic nephropathy.
Volume: 113
Pages: 154405
Publication
First Author: Jensen D
Year: 2017
Journal: PLoS One
Title: Megalin dependent urinary cystatin C excretion in ischemic kidney injury in rats.
Volume: 12
Issue: 6
Pages: e0178796
Publication
First Author: Weyer K
Year: 2011
Journal: Nephrol Dial Transplant
Title: Mouse model of proximal tubule endocytic dysfunction.
Volume: 26
Issue: 11
Pages: 3446-51
Publication
First Author: Janssens V
Year: 2019
Journal: J Am Soc Nephrol
Title: Protection of Cystinotic Mice by Kidney-Specific Megalin Ablation Supports an Endocytosis-Based Mechanism for Nephropathic Cystinosis Progression.
Volume: 30
Issue: 11
Pages: 2177-2190
Publication
First Author: Amsellem S
Year: 2010
Journal: J Am Soc Nephrol
Title: Cubilin is essential for albumin reabsorption in the renal proximal tubule.
Volume: 21
Issue: 11
Pages: 1859-67
Publication
First Author: Christensen EI
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules.
Volume: 100
Issue: 14
Pages: 8472-7
Publication
First Author: Shrestha S
Year: 2018
Journal: Sci Rep
Title: Circulating FABP4 is eliminated by the kidney via glomerular filtration followed by megalin-mediated reabsorption.
Volume: 8
Issue: 1
Pages: 16451
Publication
First Author: Bacic D
Year: 2003
Journal: Pflugers Arch
Title: Impaired PTH-induced endocytotic down-regulation of the renal type IIa Na+/Pi-cotransporter in RAP-deficient mice with reduced megalin expression.
Volume: 446
Issue: 4
Pages: 475-84
Publication  
First Author: Smith BT
Year: 2006
Journal: BMC Dev Biol
Title: Targeted disruption of cubilin reveals essential developmental roles in the structure and function of endoderm and in somite formation.
Volume: 6
Pages: 30
Publication
First Author: Xia YR
Year: 1993
Journal: Genomics
Title: Mapping of the glycoprotein 330 (Gp330) gene to mouse chromosome 2.
Volume: 17
Issue: 3
Pages: 780-1
Publication
First Author: Schulz LC
Year: 2011
Journal: Reproduction
Title: Dynamic changes in leptin distribution in the progression from ovum to blastocyst of the pre-implantation mouse embryo.
Volume: 141
Issue: 6
Pages: 767-77
Publication
First Author: Shah M
Year: 2013
Journal: J Cell Biol
Title: ARH directs megalin to the endocytic recycling compartment to regulate its proteolysis and gene expression.
Volume: 202
Issue: 1
Pages: 113-27
Publication  
First Author: Jakovac H
Year: 2018
Journal: Neuroscience
Title: Expression Profiles of Metallothionein I/II and Megalin in Cuprizone Model of De- and Remyelination.
Volume: 388
Pages: 69-86
Publication
First Author: Causeret F
Year: 2016
Journal: Cell Death Differ
Title: Kremen1 and Dickkopf1 control cell survival in a Wnt-independent manner.
Volume: 23
Issue: 2
Pages: 323-32
Publication
First Author: Muramatsu H
Year: 2000
Journal: Biochem Biophys Res Commun
Title: LDL receptor-related protein as a component of the midkine receptor.
Volume: 270
Issue: 3
Pages: 936-41
Publication
First Author: Nada S
Year: 2009
Journal: EMBO J
Title: The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK-ERK pathway to late endosomes.
Volume: 28
Issue: 5
Pages: 477-89
Publication
First Author: Yang DH
Year: 2002
Journal: Dev Biol
Title: Disabled-2 is essential for endodermal cell positioning and structure formation during mouse embryogenesis.
Volume: 251
Issue: 1
Pages: 27-44
Publication
First Author: Maurer ME
Year: 2005
Journal: J Cell Sci
Title: Endocytosis of megalin by visceral endoderm cells requires the Dab2 adaptor protein.
Volume: 118
Issue: Pt 22
Pages: 5345-55
Publication
First Author: Dubreuil V
Year: 2007
Journal: J Cell Biol
Title: Midbody and primary cilium of neural progenitors release extracellular membrane particles enriched in the stem cell marker prominin-1.
Volume: 176
Issue: 4
Pages: 483-95
Publication
First Author: Alvira-Botero X
Year: 2010
Journal: Mol Cell Neurosci
Title: Megalin interacts with APP and the intracellular adapter protein FE65 in neurons.
Volume: 45
Issue: 3
Pages: 306-15
Publication
First Author: Ye F
Year: 2019
Journal: Arterioscler Thromb Vasc Biol
Title: Angiotensinogen and Megalin Interactions Contribute to Atherosclerosis-Brief Report.
Volume: 39
Issue: 2
Pages: 150-155