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Search results 1 to 100 out of 191 for Acvr1

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Category: Publication
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Type Details Score
Publication
- | J:71753
     
First Author: Shimizu T
Year: 2001
Journal: MGI Direct Data Submission
Title: Mapping of Acvr1 to mouse Chromosome 2
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Publication
22508565 | J:194134
First Author: Chakkalakal SA
Year: 2012
Journal: J Bone Miner Res
Title: An Acvr1 R206H knock-in mouse has fibrodysplasia ossificans progressiva.
Volume: 27
Issue: 8
Pages: 1746-56
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Publication
26116174 | J:233662
First Author: Noda K
Year: 2016
Journal: Dev Biol
Title: Constitutively active mutation of ACVR1 in oral epithelium causes submucous cleft palate in mice.
Volume: 415
Issue: 2
Pages: 306-313
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Publication
32142668 | J:285841
First Author: Fortin J
Year: 2020
Journal: Cancer Cell
Title: Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas.
Volume: 37
Issue: 3
Pages: 308-323.e12
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Publication
30833574 | J:273261
First Author: Hoeman CM
Year: 2019
Journal: Nat Commun
Title: ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis.
Volume: 10
Issue: 1
Pages: 1023
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Publication
32515349 | J:291093
   
First Author: Aykul S
Year: 2020
Journal: Elife
Title: Activin A forms a non-signaling complex with ACVR1 and type II Activin/BMP receptors via its finger 2 tip loop.
Volume: 9
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Publication
33217406 | J:302550
 
First Author: Towler OW
Year: 2021
Journal: Dev Biol
Title: Dysregulated BMP signaling through ACVR1 impairs digit joint development in fibrodysplasia ossificans progressiva (FOP).
Volume: 470
Pages: 136-146
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Publication
18566469 | J:141762
First Author: Rajagopal R
Year: 2008
Journal: Invest Ophthalmol Vis Sci
Title: Functions of the type 1 BMP receptor Acvr1 (Alk2) in lens development: cell proliferation, terminal differentiation, and survival.
Volume: 49
Issue: 11
Pages: 4953-60
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Publication
30519900 | J:325430
First Author: Zhang X
Year: 2019
Journal: J Mol Histol
Title: Distinctive role of ACVR1 in dentin formation: requirement for dentin thickness in molars and prevention of osteodentin formation in incisors of mice.
Volume: 50
Issue: 1
Pages: 43-61
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Publication
21945937 | J:178480
First Author: Kamiya N
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Loss-of-function of ACVR1 in osteoblasts increases bone mass and activates canonical Wnt signaling through suppression of Wnt inhibitors SOST and DKK1.
Volume: 414
Issue: 2
Pages: 326-30
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Publication
21504908 | J:174241
First Author: Wiley LA
Year: 2011
Journal: Dis Model Mech
Title: The tumor suppressor gene Trp53 protects the mouse lens against posterior subcapsular cataracts and the BMP receptor Acvr1 acts as a tumor suppressor in the lens.
Volume: 4
Issue: 4
Pages: 484-95
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Publication
23115204 | J:193724
First Author: Kaplan FS
Year: 2012
Journal: Dis Model Mech
Title: Fibrodysplasia ossificans progressiva: mechanisms and models of skeletal metamorphosis.
Volume: 5
Issue: 6
Pages: 756-62
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Publication
25722188 | J:221139
First Author: Agarwal S
Year: 2015
Journal: Dev Biol
Title: BMP signaling mediated by constitutively active Activin type 1 receptor (ACVR1) results in ectopic bone formation localized to distal extremity joints.
Volume: 400
Issue: 2
Pages: 202-9
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Publication
28851540 | J:262510
 
First Author: Brennan TA
Year: 2018
Journal: Bone
Title: Mast cell inhibition as a therapeutic approach in fibrodysplasia ossificans progressiva (FOP).
Volume: 109
Pages: 259-266
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Publication
27881824 | J:239135
First Author: Dey D
Year: 2016
Journal: Sci Transl Med
Title: Two tissue-resident progenitor lineages drive distinct phenotypes of heterotopic ossification.
Volume: 8
Issue: 366
Pages: 366ra163
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Publication
33705358 | J:322265
 
First Author: Williams E
Year: 2021
Journal: JCI Insight
Title: Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva.
Volume: 6
Issue: 8
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Publication
26333933 | J:234069
First Author: Hatsell SJ
Year: 2015
Journal: Sci Transl Med
Title: ACVR1R206H receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A.
Volume: 7
Issue: 303
Pages: 303ra137
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Publication
35503416 | J:340538
 
First Author: Lees-Shepard JB
Year: 2022
Journal: J Clin Invest
Title: An anti-ACVR1 antibody exacerbates heterotopic ossification by fibro-adipogenic progenitors in fibrodysplasia ossificans progressiva mice.
Volume: 132
Issue: 12
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Publication
30379592 | J:318526
First Author: Haupt J
Year: 2019
Journal: Mol Biol Cell
Title: ACVR1R206H FOP mutation alters mechanosensing and tissue stiffness during heterotopic ossification.
Volume: 30
Issue: 1
Pages: 17-29
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23572558 | J:204497
First Author: Bagarova J
Year: 2013
Journal: Mol Cell Biol
Title: Constitutively active ALK2 receptor mutants require type II receptor cooperation.
Volume: 33
Issue: 12
Pages: 2413-24
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25232183 | J:232455
First Author: Peterson JR
Year: 2014
Journal: Stem Cells Transl Med
Title: Targeting of ALK2, a Receptor for Bone Morphogenetic Proteins, Using the Cre/lox System to Enhance Osseous Regeneration by Adipose-Derived Stem Cells.
Volume: 3
Issue: 11
Pages: 1375-80
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29396429 | J:257905
First Author: Lees-Shepard JB
Year: 2018
Journal: Nat Commun
Title: Activin-dependent signaling in fibro/adipogenic progenitors causes fibrodysplasia ossificans progressiva.
Volume: 9
Issue: 1
Pages: 471
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36116371 | J:330323
 
First Author: Yamaguchi H
Year: 2022
Journal: Biochem Biophys Res Commun
Title: Enhanced BMP signaling through ALK2 attenuates keratinocyte differentiation.
Volume: 629
Pages: 101-105
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15531373 | J:95020
First Author: Kishigami S
Year: 2004
Journal: Dev Biol
Title: BMP signaling through ACVRI is required for left-right patterning in the early mouse embryo.
Volume: 276
Issue: 1
Pages: 185-93
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31571391 | J:302777
First Author: Ishan M
Year: 2020
Journal: Genesis
Title: Increased activity of mesenchymal ALK2-BMP signaling causes posteriorly truncated microglossia and disorganization of lingual tissues.
Volume: 58
Issue: 1
Pages: e23337
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27029473 | J:294378
First Author: Zhou X
Year: 2016
Journal: J Endocrinol
Title: Normal gonadotropin production and fertility in gonadotrope-specific Bmpr1a knockout mice.
Volume: 229
Issue: 3
Pages: 331-41
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25413979 | J:233359
First Author: Rigueur D
Year: 2015
Journal: J Bone Miner Res
Title: The type I BMP receptor ACVR1/ALK2 is required for chondrogenesis during development.
Volume: 30
Issue: 4
Pages: 733-41
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Publication
31619522 | J:282968
First Author: Omi M
Year: 2019
Journal: J Biol Chem
Title: Activin A receptor type 1-mediated BMP signaling regulates RANKL-induced osteoclastogenesis via canonical SMAD-signaling pathway.
Volume: 294
Issue: 47
Pages: 17818-17836
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Publication
27048979 | J:251344
 
First Author: Shi C
Year: 2016
Journal: Sci Rep
Title: Deletion of BMP receptor type IB decreased bone mass in association with compromised osteoblastic differentiation of bone marrow mesenchymal progenitors.
Volume: 6
Pages: 24256
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19733164 | J:154465
First Author: Rajagopal R
Year: 2009
Journal: Dev Biol
Title: The type I BMP receptors, Bmpr1a and Acvr1, activate multiple signaling pathways to regulate lens formation.
Volume: 335
Issue: 2
Pages: 305-16
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23595735 | J:196652
First Author: Choe Y
Year: 2013
Journal: J Neurosci
Title: Bone morphogenic protein signaling is a major determinant of dentate development.
Volume: 33
Issue: 16
Pages: 6766-75
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30854720 | J:276702
First Author: Hildebrand L
Year: 2019
Journal: Dev Dyn
Title: Limb specific Acvr1-knockout during embryogenesis in mice exhibits great toe malformation as seen in Fibrodysplasia Ossificans Progressiva (FOP).
Volume: 248
Issue: 5
Pages: 396-403
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Publication
34206078 | J:336074
 
First Author: Lyu H
Year: 2021
Journal: Biomedicines
Title: MyD88 Is Not Required for Muscle Injury-Induced Endochondral Heterotopic Ossification in a Mouse Model of Fibrodysplasia Ossificans Progressiva.
Volume: 9
Issue: 6
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Publication
28641928 | J:248982
First Author: Pan H
Year: 2017
Journal: Dev Biol
Title: BmpR1A is a major type 1 BMP receptor for BMP-Smad signaling during skull development.
Volume: 429
Issue: 1
Pages: 260-270
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24680892 | J:212416
First Author: Thomas PS
Year: 2014
Journal: Dev Biol
Title: AcvR1-mediated BMP signaling in second heart field is required for arterial pole development: implications for myocardial differentiation and regional identity.
Volume: 390
Issue: 2
Pages: 191-207
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21831921 | J:175828
First Author: Komatsu Y
Year: 2011
Journal: Development
Title: Cell cycle arrest in node cells governs ciliogenesis at the node to break left-right symmetry.
Volume: 138
Issue: 18
Pages: 3915-20
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8388127 | J:25557
First Author: Ebner R
Year: 1993
Journal: Science
Title: Cloning of a type I TGF-beta receptor and its effect on TGF-beta binding to the type II receptor.
Volume: 260
Issue: 5112
Pages: 1344-8
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16140292 | J:103532
First Author: Wang J
Year: 2005
Journal: Dev Biol
Title: Atrioventricular cushion transformation is mediated by ALK2 in the developing mouse heart.
Volume: 286
Issue: 1
Pages: 299-310
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26896819 | J:239136
First Author: Chakkalakal SA
Year: 2016
Journal: J Bone Miner Res
Title: Palovarotene Inhibits Heterotopic Ossification and Maintains Limb Mobility and Growth in Mice With the Human ACVR1(R206H) Fibrodysplasia Ossificans Progressiva (FOP) Mutation.
Volume: 31
Issue: 9
Pages: 1666-75
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24449086 | J:225253
First Author: Culbert AL
Year: 2014
Journal: Stem Cells
Title: Alk2 regulates early chondrogenic fate in fibrodysplasia ossificans progressiva heterotopic endochondral ossification.
Volume: 32
Issue: 5
Pages: 1289-300
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Publication
11747203 | J:73148
First Author: Kaartinen V
Year: 2001
Journal: Genesis
Title: Removal of the floxed neo gene from a conditional knockout allele by the adenoviral Cre recombinase in vivo.
Volume: 31
Issue: 3
Pages: 126-9
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30698141 | J:275848
   
First Author: Pacifici M
Year: 2019
Journal: Elife
Title: Comment on 'Palovarotene reduces heterotopic ossification in juvenile FOP mice but exhibits pronounced skeletal toxicity'.
Volume: 8
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30698142 | J:275997
   
First Author: Goldhamer DJ
Year: 2019
Journal: Elife
Title: Response to comment on 'Palovarotene reduces heterotopic ossification in juvenile FOP mice but exhibits pronounced skeletal toxicity'.
Volume: 8
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Publication
10704880 | J:61348
First Author: Yoshikawa SI
Year: 2000
Journal: Mech Dev
Title: The ActR-I activin receptor protein is expressed in notochord, lens placode and pituitary primordium cells in the mouse embryo.
Volume: 91
Issue: 1-2
Pages: 439-44
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Publication
12054694 | J:77383
First Author: de Caestecker MP
Year: 2002
Journal: Biochem Biophys Res Commun
Title: The novel type I serine-threonine kinase receptor Alk8 binds TGF-beta in the presence of TGF-betaRII.
Volume: 293
Issue: 5
Pages: 1556-65
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10949078 | J:63647
First Author: Peng C
Year: 2000
Journal: Biochem Cell Biol
Title: Activins and their receptors in female reproduction.
Volume: 78
Issue: 3
Pages: 261-79
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21377447 | J:171940
First Author: Ohte S
Year: 2011
Journal: Biochem Biophys Res Commun
Title: A novel mutation of ALK2, L196P, found in the most benign case of fibrodysplasia ossificans progressiva activates BMP-specific intracellular signaling equivalent to a typical mutation, R206H.
Volume: 407
Issue: 1
Pages: 213-8
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Publication
33851764 | J:304330
   
First Author: Yang J
Year: 2021
Journal: Genesis
Title: Generation of a new mouse line with conditionally activated signaling through the BMP receptor, ACVR1: A tool to characterize pleiotropic roles of BMP functions.
Pages: e23419
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15037318 | J:90453
First Author: Dudas M
Year: 2004
Journal: Mech Dev
Title: Craniofacial defects in mice lacking BMP type I receptor Alk2 in neural crest cells.
Volume: 121
Issue: 2
Pages: 173-82
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24244176 | J:223045
First Author: Clementi C
Year: 2013
Journal: PLoS Genet
Title: Activin-like kinase 2 functions in peri-implantation uterine signaling in mice and humans.
Volume: 9
Issue: 11
Pages: e1003863
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Publication
24501215 | J:210176
First Author: Mayeur C
Year: 2014
Journal: Blood
Title: The type I BMP receptor Alk3 is required for the induction of hepatic hepcidin gene expression by interleukin-6.
Volume: 123
Issue: 14
Pages: 2261-8
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Publication
26148958 | J:228773
First Author: Chen SY
Year: 2015
Journal: Stem Cells
Title: HC-HA/PTX3 Purified From Amniotic Membrane Promotes BMP Signaling in Limbal Niche Cells to Maintain Quiescence of Limbal Epithelial Progenitor/Stem Cells.
Volume: 33
Issue: 11
Pages: 3341-55
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11290335 | J:68348
First Author: Izon DJ
Year: 2001
Journal: Immunity
Title: Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength.
Volume: 14
Issue: 3
Pages: 253-64
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7639738 | J:27982
First Author: Schmitt J
Year: 1995
Journal: Biochem Biophys Res Commun
Title: Genomic organization of a mouse type I activin receptor.
Volume: 213
Issue: 1
Pages: 211-7
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1646080 | J:11226
First Author: Mathews LS
Year: 1991
Journal: Cell
Title: Expression cloning of an activin receptor, a predicted transmembrane serine kinase.
Volume: 65
Issue: 6
Pages: 973-82
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33741934 | J:303825
First Author: Ryanto GRT
Year: 2021
Journal: Nat Commun
Title: An endothelial activin A-bone morphogenetic protein receptor type 2 link is overdriven in pulmonary hypertension.
Volume: 12
Issue: 1
Pages: 1720
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23485971 | J:195128
First Author: Schulz TJ
Year: 2013
Journal: Nature
Title: Brown-fat paucity due to impaired BMP signalling induces compensatory browning of white fat.
Volume: 495
Issue: 7441
Pages: 379-83
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21841161 | J:178403
First Author: Steinbicker AU
Year: 2011
Journal: Blood
Title: Perturbation of hepcidin expression by BMP type I receptor deletion induces iron overload in mice.
Volume: 118
Issue: 15
Pages: 4224-30
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28191871 | J:241217
   
First Author: Coda DM
Year: 2017
Journal: Elife
Title: Distinct modes of SMAD2 chromatin binding and remodeling shape the transcriptional response to NODAL/Activin signaling.
Volume: 6
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28864813 | J:251859
First Author: Colucci S
Year: 2017
Journal: Blood
Title: The immunophilin FKBP12 inhibits hepcidin expression by binding the BMP type I receptor ALK2 in hepatocytes.
Volume: 130
Issue: 19
Pages: 2111-2120
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30227271 | J:295633
 
First Author: Traeger L
Year: 2018
Journal: Free Radic Biol Med
Title: ALK3 undergoes ligand-independent homodimerization and BMP-induced heterodimerization with ALK2.
Volume: 129
Pages: 127-137
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28468752 | J:243432
First Author: Zhou F
Year: 2017
Journal: EMBO J
Title: USP4 inhibits SMAD4 monoubiquitination and promotes activin and BMP signaling.
Volume: 36
Issue: 11
Pages: 1623-1639
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26873969 | J:232934
First Author: Shahid M
Year: 2016
Journal: Am J Physiol Heart Circ Physiol
Title: BMP type I receptor ALK2 is required for angiotensin II-induced cardiac hypertrophy.
Volume: 310
Issue: 8
Pages: H984-94
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Publication
24116187 | J:209027
First Author: Leyton PA
Year: 2013
Journal: PLoS One
Title: Deletion of the sequence encoding the tail domain of the bone morphogenetic protein type 2 receptor reveals a bone morphogenetic protein 7-specific gain of function.
Volume: 8
Issue: 10
Pages: e76947
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1326537 | J:2521
First Author: Nakamura T
Year: 1992
Journal: J Biol Chem
Title: Isolation and characterization of activin receptor from mouse embryonal carcinoma cells. Identification of its serine/threonine/tyrosine protein kinase activity.
Volume: 267
Issue: 26
Pages: 18924-8
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11376112 | J:69633
First Author: Visser JA
Year: 2001
Journal: Mol Endocrinol
Title: The serine/threonine transmembrane receptor ALK2 mediates Müllerian inhibiting substance signaling.
Volume: 15
Issue: 6
Pages: 936-45
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8605036 | J:164795
First Author: Agrotis A
Year: 1996
Journal: Biochem Biophys Res Commun
Title: Vascular smooth muscle cells express multiple type I receptors for TGF-beta, activin, and bone morphogenetic proteins.
Volume: 219
Issue: 2
Pages: 613-8
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20628059 | J:166395
First Author: Luo J
Year: 2010
Journal: J Biol Chem
Title: TGFbeta/BMP type I receptors ALK1 and ALK2 are essential for BMP9-induced osteogenic signaling in mesenchymal stem cells.
Volume: 285
Issue: 38
Pages: 29588-98
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24141051 | J:215732
 
First Author: Podkowa M
Year: 2013
Journal: Mol Cell Neurosci
Title: p21-Activated kinase (PAK) is required for Bone Morphogenetic Protein (BMP)-induced dendritogenesis in cortical neurons.
Volume: 57
Pages: 83-92
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26083127 | J:225912
First Author: Liang GJ
Year: 2015
Journal: Stem Cells Dev
Title: Activin A accelerates the progression of fetal oocytes throughout meiosis and early oogenesis in the mouse.
Volume: 24
Issue: 20
Pages: 2455-65
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10479450 | J:57670
First Author: Mishina Y
Year: 1999
Journal: Dev Biol
Title: Multiple roles for activin-like kinase-2 signaling during mouse embryogenesis.
Volume: 213
Issue: 2
Pages: 314-26
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7577669 | J:27756
First Author: Verschueren K
Year: 1995
Journal: Mech Dev
Title: Expression of type I and type IB receptors for activin in midgestation mouse embryos suggests distinct functions in organogenesis.
Volume: 52
Issue: 1
Pages: 109-23
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18322278 | J:140810
First Author: Orvis GD
Year: 2008
Journal: Biol Reprod
Title: Functional redundancy of TGF-beta family type I receptors and receptor-Smads in mediating anti-Mullerian hormone-induced Mullerian duct regression in the mouse.
Volume: 78
Issue: 6
Pages: 994-1001
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12141440 | J:80723
First Author: Martinez G
Year: 2002
Journal: Int J Dev Biol
Title: BMPs and BMP receptors in mouse metanephric development: in vivo and in vitro studies.
Volume: 46
Issue: 4
Pages: 525-33
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Publication
17078885 | J:119667
 
First Author: Wang J
Year: 2006
Journal: BMC Dev Biol
Title: Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects.
Volume: 6
Pages: 51
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Publication
25641697 | J:221163
First Author: Lim J
Year: 2015
Journal: Dev Biol
Title: BMP-Smad4 signaling is required for precartilaginous mesenchymal condensation independent of Sox9 in the mouse.
Volume: 400
Issue: 1
Pages: 132-8
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Publication
30548566 | J:273379
First Author: Kronander E
Year: 2019
Journal: Dev Neurobiol
Title: Role of BMP Signaling for the Formation of Auditory Brainstem Nuclei and Large Auditory Relay Synapses.
Volume: 79
Issue: 2
Pages: 155-174
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Publication
28232325 | J:263613
First Author: Lee HW
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: Alk2/ACVR1 and Alk3/BMPR1A Provide Essential Function for Bone Morphogenetic Protein-Induced Retinal Angiogenesis.
Volume: 37
Issue: 4
Pages: 657-663
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Publication
31800957 | J:335613
First Author: Wang CY
Year: 2020
Journal: Blood
Title: Erythroferrone lowers hepcidin by sequestering BMP2/6 heterodimer from binding to the BMP type I receptor ALK3.
Volume: 135
Issue: 6
Pages: 453-456
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Publication
10226013 | J:54394
First Author: Gu Z
Year: 1999
Journal: Development
Title: The type I serine/threonine kinase receptor ActRIA (ALK2) is required for gastrulation of the mouse embryo.
Volume: 126
Issue: 11
Pages: 2551-61
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Publication
12151307 | J:116258
First Author: Rosendahl A
Year: 2002
Journal: Am J Respir Cell Mol Biol
Title: Activation of bone morphogenetic protein/Smad signaling in bronchial epithelial cells during airway inflammation.
Volume: 27
Issue: 2
Pages: 160-9
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Publication
16157679 | J:105164
First Author: Fernández-Valdivia R
Year: 2006
Journal: Genetics
Title: l7Rn6 encodes a novel protein required for clara cell function in mouse lung development.
Volume: 172
Issue: 1
Pages: 389-99
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Publication
21451961 | J:171917
First Author: Mollah MB
Year: 2011
Journal: Mamm Genome
Title: Intersubspecific subcongenic mouse strain analysis reveals closely linked QTLs with opposite effects on body weight.
Volume: 22
Issue: 5-6
Pages: 282-9
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Publication
17117439 | J:117234
First Author: Komatsu Y
Year: 2007
Journal: Dev Dyn
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