|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 336 for Blm

<< First    < Previous  |  Next >    Last >>
0.021s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: frog, western clawed
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Goss KH
Year: 2002
Journal: Science
Title: Enhanced tumor formation in mice heterozygous for Blm mutation.
Volume: 297
Issue: 5589
Pages: 2051-3
Publication
First Author: van Wietmarschen N
Year: 2018
Journal: Nat Commun
Title: BLM helicase suppresses recombination at G-quadruplex motifs in transcribed genes.
Volume: 9
Issue: 1
Pages: 271
Publication
First Author: McDaniel LD
Year: 2003
Journal: DNA Repair (Amst)
Title: Chromosome instability and tumor predisposition inversely correlate with BLM protein levels.
Volume: 2
Issue: 12
Pages: 1387-404
Publication
First Author: Drosopoulos WC
Year: 2015
Journal: J Cell Biol
Title: BLM helicase facilitates telomere replication during leading strand synthesis of telomeres.
Volume: 210
Issue: 2
Pages: 191-208
Publication
First Author: Davari P
Year: 2010
Journal: Carcinogenesis
Title: Loss of Blm enhances basal cell carcinoma and rhabdomyosarcoma tumorigenesis in Ptch1+/- mice.
Volume: 31
Issue: 6
Pages: 968-73
Publication
First Author: Bahr A
Year: 1998
Journal: Oncogene
Title: Point mutations causing Bloom's syndrome abolish ATPase and DNA helicase activities of the BLM protein.
Volume: 17
Issue: 20
Pages: 2565-71
Publication
First Author: Chen CF
Year: 2010
Journal: EMBO J
Title: An essential DNA strand-exchange activity is conserved in the divergent N-termini of BLM orthologs.
Volume: 29
Issue: 10
Pages: 1713-25
Publication
First Author: Patel DS
Year: 2017
Journal: J Cell Biol
Title: BLM helicase regulates DNA repair by counteracting RAD51 loading at DNA double-strand break sites.
Volume: 216
Issue: 11
Pages: 3521-3534
Publication
First Author: Holloway JK
Year: 2010
Journal: J Cell Biol
Title: Mammalian BLM helicase is critical for integrating multiple pathways of meiotic recombination.
Volume: 188
Issue: 6
Pages: 779-89
Publication
First Author: El Ghamrasni S
Year: 2015
Journal: Oncogene
Title: Cooperation of Blm and Mus81 in development, fertility, genomic integrity and cancer suppression.
Volume: 34
Issue: 14
Pages: 1780-9
Publication
First Author: Chu WK
Year: 2010
Journal: Oncogene
Title: BLM has early and late functions in homologous recombination repair in mouse embryonic stem cells.
Volume: 29
Issue: 33
Pages: 4705-14
Publication
First Author: Babbe H
Year: 2009
Journal: J Immunol
Title: Genomic instability resulting from Blm deficiency compromises development, maintenance, and function of the B cell lineage.
Volume: 182
Issue: 1
Pages: 347-60
Publication
First Author: Kim TM
Year: 2015
Journal: Nucleic Acids Res
Title: RECQL5 and BLM exhibit divergent functions in cells defective for the Fanconi anemia pathway.
Volume: 43
Issue: 2
Pages: 893-903
Publication
First Author: Sengupta S
Year: 2004
Journal: J Cell Biol
Title: Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest.
Volume: 166
Issue: 6
Pages: 801-13
Publication
First Author: Zimmermann M
Year: 2014
Journal: Genes Dev
Title: TRF1 negotiates TTAGGG repeat-associated replication problems by recruiting the BLM helicase and the TPP1/POT1 repressor of ATR signaling.
Volume: 28
Issue: 22
Pages: 2477-91
Publication
First Author: Seki T
Year: 1998
Journal: Biochim Biophys Acta
Title: cDNA cloning of mouse BLM gene, the homologue to human Bloom's syndrome gene, which is highly expressed in the testis at the mRNA level.
Volume: 1398
Issue: 3
Pages: 377-81
GXD Expression  
Probe: MGI:7544968
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-01
Strength: Present
Sex: Female
Emaps: EMAPS:1657819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:7545025
Age: embryonic day 11.5
Note: The proportion of Blm positive cells was significantly decreased compared with the wild-type (quantified in Fig 8B).
Specimen Label: 8A E11.5 -/-
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:7544968
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-01
Strength: Present
Sex: Female
Emaps: EMAPS:1657820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7545025
Age: embryonic day 12.5
Note: The proportion of Blm positive cells was significantly decreased compared with the wild-type (quantified in Fig 8B).
Specimen Label: 8A E12.5 -/-
Detected: true
Specimen Num: 4
Publication
First Author: Bononi A
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Heterozygous germline BLM mutations increase susceptibility to asbestos and mesothelioma.
Volume: 117
Issue: 52
Pages: 33466-33473
Publication
First Author: Yusa K
Year: 2004
Journal: Nature
Title: Genome-wide phenotype analysis in ES cells by regulated disruption of Bloom's syndrome gene.
Volume: 429
Issue: 6994
Pages: 896-9
Publication
First Author: LaRocque JR
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Interhomolog recombination and loss of heterozygosity in wild-type and Bloom syndrome helicase (BLM)-deficient mammalian cells.
Volume: 108
Issue: 29
Pages: 11971-6
Publication  
First Author: Hayakawa T
Year: 2006
Journal: Gene
Title: Bloom's syndrome gene-deficient phenotype in mouse primary cells induced by a modified tetracycline-controlled trans-silencer.
Volume: 369
Pages: 80-9
Publication
First Author: Schlacher K
Year: 2012
Journal: Cancer Cell
Title: A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2.
Volume: 22
Issue: 1
Pages: 106-16
Publication
First Author: Walpita D
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Bloom's syndrome protein, BLM, colocalizes with replication protein A in meiotic prophase nuclei of mammalian spermatocytes.
Volume: 96
Issue: 10
Pages: 5622-7
Publication
First Author: Yamanishi A
Year: 2013
Journal: Genome Res
Title: Enhancement of microhomology-mediated genomic rearrangements by transient loss of mouse Bloom syndrome helicase.
Volume: 23
Issue: 9
Pages: 1462-73
Publication
First Author: Chester N
Year: 2006
Journal: Mol Cell Biol
Title: Mutation of the murine Bloom's syndrome gene produces global genome destabilization.
Volume: 26
Issue: 17
Pages: 6713-26
Publication
First Author: Babbe H
Year: 2007
Journal: Mol Cell Biol
Title: The Bloom's syndrome helicase is critical for development and function of the alphabeta T-cell lineage.
Volume: 27
Issue: 5
Pages: 1947-59
Publication
First Author: Wang Y
Year: 2004
Journal: Mutat Res
Title: Spontaneous and induced chromosomal damage and mutations in Bloom Syndrome mice.
Volume: 554
Issue: 1-2
Pages: 131-7
Publication
First Author: Urtishak KA
Year: 2009
Journal: J Biol Chem
Title: Timeless Maintains Genomic Stability and Suppresses Sister Chromatid Exchange during Unperturbed DNA Replication.
Volume: 284
Issue: 13
Pages: 8777-85
Publication
First Author: Du X
Year: 2004
Journal: Mol Cell Biol
Title: Telomere shortening exposes functions for the mouse Werner and Bloom syndrome genes.
Volume: 24
Issue: 19
Pages: 8437-46
Publication
First Author: Chester N
Year: 1998
Journal: Genes Dev
Title: Stage-specific apoptosis, developmental delay, and embryonic lethality in mice homozygous for a targeted disruption in the murine Bloom's syndrome gene.
Volume: 12
Issue: 21
Pages: 3382-93
Publication
First Author: Wilson C
Year: 2005
Journal: Cancer Res
Title: Induction of renal tumorigenesis with elevated levels of somatic loss of heterozygosity in Tsc1+/- mice on a Blm-deficient background.
Volume: 65
Issue: 22
Pages: 10179-82
Publication
First Author: Brown AD
Year: 2011
Journal: Mol Cell Biol
Title: A conditional mouse model for measuring the frequency of homologous recombination events in vivo in the absence of essential genes.
Volume: 31
Issue: 17
Pages: 3593-602
Publication
First Author: Zhao B
Year: 2018
Journal: Cell Res
Title: Mouse embryonic stem cells have increased capacity for replication fork restart driven by the specific Filia-Floped protein complex.
Volume: 28
Issue: 1
Pages: 69-89
Publication
First Author: Jacome A
Year: 2015
Journal: EMBO J
Title: NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activity.
Volume: 34
Issue: 21
Pages: 2604-19
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Weber J
Year: 2019
Journal: Nat Commun
Title: PiggyBac transposon tools for recessive screening identify B-cell lymphoma drivers in mice.
Volume: 10
Issue: 1
Pages: 1415
Publication
First Author: Suzuki T
Year: 2006
Journal: EMBO J
Title: Tumor suppressor gene identification using retroviral insertional mutagenesis in Blm-deficient mice.
Volume: 25
Issue: 14
Pages: 3422-31
GXD Expression      
Probe: MGI:1334598
Assay Type: Northern blot
Annotation Date: 1999-06-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:1337786
Age: postnatal month 2
Specimen Label: SP
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:1334598
Assay Type: Northern blot
Annotation Date: 1999-06-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:1337786
Age: postnatal month 2
Specimen Label: K
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:1334598
Assay Type: Northern blot
Annotation Date: 1999-06-14
Strength: Present
Sex: Female
Emaps: EMAPS:1775928
Stage: TS28
Assay Id: MGI:1337786
Age: postnatal month 2
Specimen Label: MG
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:1334598
Assay Type: Northern blot
Annotation Date: 1999-06-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1925228
Stage: TS28
Assay Id: MGI:1337786
Age: postnatal month 2
Specimen Label: LI
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:1334598
Assay Type: Northern blot
Annotation Date: 1999-06-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:1337786
Age: postnatal month 2
Specimen Label: C
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:1334598
Assay Type: Northern blot
Annotation Date: 1999-06-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:1337786
Age: postnatal month 2
Specimen Label: LG
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:1334598
Assay Type: Northern blot
Annotation Date: 1999-06-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:1337786
Age: postnatal month 2
Specimen Label: H
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:1334598
Assay Type: Northern blot
Annotation Date: 1999-06-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:1337785
Age: embryonic day 9.5
Specimen Label: 9.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:1334598
Assay Type: Northern blot
Annotation Date: 1999-06-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:1337785
Age: embryonic day 10.5
Specimen Label: 10.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:1334598
Assay Type: Northern blot
Annotation Date: 1999-06-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:1337785
Age: embryonic day 11.5
Specimen Label: 11.5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:1334598
Assay Type: Northern blot
Annotation Date: 1999-06-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:1337785
Age: embryonic day 12.5
Specimen Label: 12.5
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:1334598
Assay Type: Northern blot
Annotation Date: 1999-06-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:1337785
Age: embryonic day 13.5
Specimen Label: 13.5
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:1334598
Assay Type: Northern blot
Annotation Date: 1999-06-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603924
Stage: TS24
Assay Id: MGI:1337785
Age: embryonic day 16.5
Specimen Label: 16.5
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3511252
Assay Type: Western blot
Annotation Date: 2004-12-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:3511296
Age: embryonic day 13.5
Specimen Label: -/-
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3511252
Assay Type: Western blot
Annotation Date: 2004-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:3511296
Age: embryonic day 13.5
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3511252
Assay Type: Western blot
Annotation Date: 2004-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:3511296
Age: embryonic day 13.5
Specimen Label: +/+
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7569051
Assay Type: RT-PCR
Annotation Date: 2023-12-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:7569058
Age: embryonic day 9.5
Specimen Label: wt
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7569051
Assay Type: RT-PCR
Annotation Date: 2023-12-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:7569058
Age: embryonic day 9.5
Specimen Label: ht/ht
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3511252
Assay Type: Western blot
Annotation Date: 2004-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684621
Stage: TS21
Assay Id: MGI:3511296
Age: embryonic day 13.5
Specimen Label: +/+
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3511252
Assay Type: Western blot
Annotation Date: 2004-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684621
Stage: TS21
Assay Id: MGI:3511296
Age: embryonic day 13.5
Specimen Label: +/-
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3511252
Assay Type: Western blot
Annotation Date: 2004-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684621
Stage: TS21
Assay Id: MGI:3511296
Age: embryonic day 13.5
Specimen Label: -/-
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3511252
Assay Type: Western blot
Annotation Date: 2004-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684621
Stage: TS21
Assay Id: MGI:3511296
Age: embryonic day 13.5
Specimen Label: -/-
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3511252
Assay Type: Western blot
Annotation Date: 2004-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684621
Stage: TS21
Assay Id: MGI:3511296
Age: embryonic day 13.5
Specimen Label: -/-
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:3511252
Assay Type: Western blot
Annotation Date: 2004-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684621
Stage: TS21
Assay Id: MGI:3511296
Age: embryonic day 13.5
Specimen Label: +/-
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:3511252
Assay Type: Western blot
Annotation Date: 2004-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684621
Stage: TS21
Assay Id: MGI:3511296
Age: embryonic day 13.5
Specimen Label: +/+
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:3511252
Assay Type: Western blot
Annotation Date: 2004-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684621
Stage: TS21
Assay Id: MGI:3511297
Age: embryonic day 13.5
Specimen Label: 8, +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3511252
Assay Type: Western blot
Annotation Date: 2004-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684621
Stage: TS21
Assay Id: MGI:3511297
Age: embryonic day 13.5
Specimen Label: 4, +/+
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3511252
Assay Type: Western blot
Annotation Date: 2004-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684621
Stage: TS21
Assay Id: MGI:3511297
Age: embryonic day 13.5
Specimen Label: 2, +/+
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3511252
Assay Type: Western blot
Annotation Date: 2004-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684621
Stage: TS21
Assay Id: MGI:3511297
Age: embryonic day 13.5
Specimen Label: 1, +/+
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3511252
Assay Type: Western blot
Annotation Date: 2004-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684621
Stage: TS21
Assay Id: MGI:3511297
Age: embryonic day 13.5
Specimen Label: 1, -/-
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3511252
Assay Type: Western blot
Annotation Date: 2004-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684621
Stage: TS21
Assay Id: MGI:3511299
Age: embryonic day 13.5
Specimen Label: +/+, 8
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3511252
Assay Type: Western blot
Annotation Date: 2004-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684621
Stage: TS21
Assay Id: MGI:3511299
Age: embryonic day 13.5
Specimen Label: +/+, 4
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3511252
Assay Type: Western blot
Annotation Date: 2004-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684621
Stage: TS21
Assay Id: MGI:3511299
Age: embryonic day 13.5
Specimen Label: +/+, 2
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3511252
Assay Type: Western blot
Annotation Date: 2004-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684621
Stage: TS21
Assay Id: MGI:3511299
Age: embryonic day 13.5
Specimen Label: +/+, 1
Detected: true
Specimen Num: 1