|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 127 out of 127 for Bms1

<< First    < Previous  |  Next >    Last >>
0.019s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
114680585 | LOC114680585
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Gene
114669953 | LOC114669953
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Gene
114676082 | LOC114676082
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Gene
114675814 | LOC114675814
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Gene
119866554 | LOC119866554
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
129135999 | LOC129135999
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
129136200 | LOC129136200
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
129136947 | LOC129136947
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
129137187 | LOC129137187
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
129137325 | LOC129137325
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
134807779 | LOC134807779
Type: gene
Organism: chimpanzee
•
•
•
•
•
DO Term
DOID:0080661 | nonsyndromic aplasia cutis congenita
•
•
•
•
•
Publication
16376378 | -
First Author: Karbstein K
Year: 2006
Journal: J Mol Biol
Title: GTP-dependent formation of a ribonucleoprotein subcomplex required for ribosome biogenesis.
Volume: 356
Issue: 2
Pages: 432-43
•
•
•
•
•
Protein Domain
IPR037875 | Bms1_N
Type: Domain
Description: Bms1 is an essential, evolutionarily conserved, nucleolar protein. Its depletion interferes with processing of the 35S pre-rRNA at sites A0, A1, and A2, and the formation of 40S subunits. Bms1, the putative endonuclease Rc11, and the essential U3 small nucleolar RNA form a stable subcomplex that is believed to control an early step in the formation of the 40S subunit []. The N terminus of Bms1 contains a guanine nucleotide-binding (G) domain that functions intramolecularly. It is believed that Rc11 activates Bms1 by acting as a guanine-nucleotide exchange factor (GEF) to promote GDP/GTP exchange, and that activated (GTP-bound) Bms1 delivers Rc11 to the preribosomes [].This entry represents the N-terminal domain of Bms1.
•
•
•
•
•
Protein Domain
IPR007034 | BMS1_TSR1_C
Type: Domain
Description: This domain is found at the C terminus of the ribosome biogenesis protein BMS1 and TSR1 families, which may act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus.
•
•
•
•
•
Publication
11565748 | -
First Author: Wegierski T
Year: 2001
Journal: RNA
Title: Bms1p, a G-domain-containing protein, associates with Rcl1p and is required for 18S rRNA biogenesis in yeast.
Volume: 7
Issue: 9
Pages: 1254-67
•
•
•
•
•
Protein
Q5SWD9
Organism: Mus musculus/domesticus
Length: 803  
Fragment?: false
•
•
•
•
•
Protein
Q6PGF5
Organism: Mus musculus/domesticus
Length: 1284  
Fragment?: false
•
•
•
•
•
Protein
Q6ZQH0
Organism: Mus musculus/domesticus
Length: 1287  
Fragment?: true
•
•
•
•
•
Protein
Q3V0N4
Organism: Mus musculus/domesticus
Length: 1223  
Fragment?: true
•
•
•
•
•
Protein Domain
IPR030387 | G_Bms1/Tsr1_dom
Type: Domain
Description: Bms1p and Tsr1p represent a new family of factors required for ribosomebiogenesis. They are each independently required for 40S ribosomal subunitbiogenesis. Bms1p, a protein required for pre-rRNA processing, contains anevolutionarily conserved guanine nucleotide-binding (G) domain with five conserved polypeptide loopsdesignated G1 through G5, which form contact sites with the guanine nucleotideor coordinate the Mg(2+) ion. Sequences resembling G1 (consensus [GA]-x(4)-G-K-[ST]; also known as a P-loop), G4 (consensus [NT]-K-x-D), and G5 (consensusS-[AG]are present in all Bms1 proteins, and either fully conform with theconsensus or contain, at most, single conservative substitutions. The G2 motif(consensus G-P-[IV]-T) contains a T residue involved in the coordination ofthe Mg(2+) required for GTP hydrolysis. The G3 motif diverges from theconsensus found in G proteins, D-x(2)-G; however, the D residue is replacedwith the conserved E residue. In contrast, Tsr1p lacks a P-loop and is notpredicted to bind GTP. It functions at a later step of 40S ribosomeproduction, possibly in assembly and/or export of 43S pre-ribosomal subunitsto the cytosol [, , ].This entry represents a domain found in Bms1 and Tsr1, and includes cases, such as Tsr1, where it may not function as a guanine nucleotide-binding domain.
•
•
•
•
•
Protein
Q3UYW7
Organism: Mus musculus/domesticus
Length: 830  
Fragment?: true
•
•
•
•
•
Protein
Q8CEG3
Organism: Mus musculus/domesticus
Length: 416  
Fragment?: true
•
•
•
•
•
Publication
11565749 | -
First Author: Gelperin D
Year: 2001
Journal: RNA
Title: Bms1p, a novel GTP-binding protein, and the related Tsr1p are required for distinct steps of 40S ribosome biogenesis in yeast.
Volume: 7
Issue: 9
Pages: 1268-83
•
•
•
•
•
Protein Domain
IPR039761 | Bms1/Tsr1
Type: Family
Description: Bms1p and Tsr1p represent a new family of factors required for ribosomebiogenesis. They are each independently required for 40S ribosomal subunitbiogenesis. Bms1p, a protein required for pre-rRNA processing, contains anevolutionarily conserved guanine nucleotide-binding (G) domain with five conserved polypeptide loopsdesignated G1 through G5, which form contact sites with the guanine nucleotideor coordinate the Mg(2+) ion. Sequences resembling G1 (consensus [GA]-x(4)-G-K-[ST]; also known as a P-loop), G4 (consensus [NT]-K-x-D), and G5 (consensusS-[AG]are present in all Bms1 proteins, and either fully conform with theconsensus or contain, at most, single conservative substitutions. The G2 motif(consensus G-P-[IV]-T) contains a T residue involved in the coordination ofthe Mg(2+) required for GTP hydrolysis. The G3 motif diverges from theconsensus found in G proteins, D-x(2)-G; however, the D residue is replacedwith the conserved E residue. In contrast, Tsr1p lacks a P-loop and is notpredicted to bind GTP. It functions at a later step of 40S ribosomeproduction, possibly in assembly and/or export of 43S pre-ribosomal subunitsto the cytosol [, , ].
•
•
•
•
•
Publication
11916378 | -
First Author: Leipe DD
Year: 2002
Journal: J Mol Biol
Title: Classification and evolution of P-loop GTPases and related ATPases.
Volume: 317
Issue: 1
Pages: 41-72
•
•
•
•
•
Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom