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Search results 101 to 148 out of 148 for Cbx7

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Type Details Score
Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
18701502 | J:139142
First Author: Pallante P
Year: 2008
Journal: Cancer Res
Title: Loss of the CBX7 gene expression correlates with a highly malignant phenotype in thyroid cancer.
Volume: 68
Issue: 16
Pages: 6770-8
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Interaction Experiment
Forzati F (2012)
Description: CBX7 is a tumor suppressor in mice and humans.
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Allele
Cbx7<tm1Smoc> | MGI:7288671
Name: chromobox 7; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Publication
20541999 | -
First Author: Yap KL
Year: 2010
Journal: Mol Cell
Title: Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a.
Volume: 38
Issue: 5
Pages: 662-74
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Strain
MGI:6354361 | B6;129S-Cbx7<tm1Smoc>/Smoc
Attribute String: targeted mutation, mutant stock
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Protein
Q8BPY2
Organism: Mus musculus/domesticus
Length: 193  
Fragment?: true
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Publication
18588675 | -
 
First Author: Sanchez-Pulido L
Year: 2008
Journal: BMC Genomics
Title: RAWUL: a new ubiquitin-like domain in PRC1 ring finger proteins that unveils putative plant and worm PRC1 orthologs.
Volume: 9
Pages: 308
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Protein Domain
IPR033773 | CBX7_C
Type: Conserved_site
Description: CBX7 and RING1B are components of a Polycomb group (PcG) multiprotein PRC1-like complex which maintains many genes, including Hox genes, transcriptionally repressed during development, signalling and cancer by recognizing trimethylated lysines on histones []. This motif is found at the C terminus of CBX7 where it binds the RAWUL domain of the RING1B protein [, ].
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Protein
Q3URA3
Organism: Mus musculus/domesticus
Length: 136  
Fragment?: true
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Protein
Q8C9Z5
Organism: Mus musculus/domesticus
Length: 117  
Fragment?: true
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Publication
23680149 | J:199004
First Author: Gargiulo G
Year: 2013
Journal: Cancer Cell
Title: In vivo RNAi screen for BMI1 targets identifies TGF-β/BMP-ER stress pathways as key regulators of neural- and malignant glioma-stem cell homeostasis.
Volume: 23
Issue: 5
Pages: 660-76
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Publication
19791798 | -
First Author: Bezsonova I
Year: 2009
Journal: Biochemistry
Title: Ring1B contains a ubiquitin-like docking module for interaction with Cbx proteins.
Volume: 48
Issue: 44
Pages: 10542-8
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Publication
25500566 | J:222656
First Author: Creppe C
Year: 2014
Journal: PLoS Genet
Title: A Cbx8-containing polycomb complex facilitates the transition to gene activation during ES cell differentiation.
Volume: 10
Issue: 12
Pages: e1004851
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Protein
Q3U240
Organism: Mus musculus/domesticus
Length: 302  
Fragment?: true
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Protein
D3YY71
Organism: Mus musculus/domesticus
Length: 61  
Fragment?: true
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Publication
12679040 | -
First Author: Kagey MH
Year: 2003
Journal: Cell
Title: The polycomb protein Pc2 is a SUMO E3.
Volume: 113
Issue: 1
Pages: 127-37
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Protein Domain
IPR043531 | CBX4
Type: Family
Description: Polycomb group (PcG) proteins were first identified in Drosophila but mammalian homologs have been identified. They interact with each other to form multimeric, chromatin-associated protein complexes. The human orthologs of the Drosophila PcG proteins are CBX2, CBX4, CBX6, CBX7 and CBX8, which exhibit distinct nuclear localisations and they contribute differently to transcriptional repression. They have been described as regulators of homeotic gene expression. It has been demonstrated that these proteins maintain the repressed state of these genes, involved in development, signalling or cancer []. PcG complexes can be recruited to DNA by interactions with specific DNA binding proteins [].Sumoylation is a reversible conjugation process similar to ubiquitination, in which proteins involved in a wide range of processes are modified, such as DNA repair, chromosome segregation and gene expression. It implies an activating enzyme (E1), a conjugating enzyme (E2), and a ligase (E3) As well as in the ubiquitination process, the E3 ligase determines substrate specificity. Polycomb protein Pc2, also known as CBX4, is a SUMO (small ubiquitin-related modifier) ligase E3. DNA damage activates CBX4 which sumoylates the heterogeneous nuclear ribonucleoprotein K (hnRNP K), a p53 cofactor required for transcriptional regulation of p53 target genes [].This entry includes de E3 SUMO-protein ligase CBX4 (also known as Pc2).
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Publication
22825850 | -
First Author: Pelisch F
Year: 2012
Journal: J Biol Chem
Title: DNA damage-induced heterogeneous nuclear ribonucleoprotein K sumoylation regulates p53 transcriptional activation.
Volume: 287
Issue: 36
Pages: 30789-99
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Protein
O55187
Organism: Mus musculus/domesticus
Length: 551  
Fragment?: false
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Protein
Q9QXV1
Organism: Mus musculus/domesticus
Length: 362  
Fragment?: false
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Protein
P30658
Organism: Mus musculus/domesticus
Length: 519  
Fragment?: false
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Protein
Q3TZG6
Organism: Mus musculus/domesticus
Length: 519  
Fragment?: false
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Protein
Q9DBY5
Organism: Mus musculus/domesticus
Length: 414  
Fragment?: false
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Protein
Q3UK98
Organism: Mus musculus/domesticus
Length: 396  
Fragment?: false
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Protein
Q6TKP2
Organism: Mus musculus/domesticus
Length: 672  
Fragment?: false
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Protein
Q05BI5
Organism: Mus musculus/domesticus
Length: 258  
Fragment?: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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