This entry represents the DNA-binding domain of COE1, COE2, COE3 and COE4 (also known as Ebf1, Ebf2, Ebf3 and Ebf4), they belong to the early B cell factor family. COE1 is a key transcriptional determinant of B-lymphocyte differentiation []. COE3 is a transcription factor involved in neuronal differentiation and maturation [].
This entry represents the DNA-binding domain of COE1, COE2, COE3 and COE4 (also known as Ebf1, Ebf2, Ebf3 and Ebf4), they belong to the early B cell factor family. COE1 is a key transcriptional determinant of B-lymphocyte differentiation []. COE3 isa transcription factor involved in neuronal differentiation and maturation [].Structurally, this domain consists of 4 alpha helices and 9 beta strands, where the beta strands are arranged into a 9-membered antiparallel barrel.
