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Search results 1 to 100 out of 154 for Tln1

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Type Details Score
Publication
- | J:131145
     
First Author: Monkley SJ
Year: 2008
Journal: MGI Direct Data Submission
Title: Creation of a conditional knock-out allele of Tln1
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Publication
38102166 | J:343630
First Author: Latour YL
Year: 2023
Journal: Sci Rep
Title: Myeloid deletion of talin-1 reduces mucosal macrophages and protects mice from colonic inflammation.
Volume: 13
Issue: 1
Pages: 22368
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Publication
21081121 | J:168021
First Author: Monkley SJ
Year: 2011
Journal: Dev Biol
Title: Endothelial cell talin1 is essential for embryonic angiogenesis.
Volume: 349
Issue: 2
Pages: 494-502
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Publication
28698364 | J:244212
First Author: Manso AM
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Loss of mouse cardiomyocyte talin-1 and talin-2 leads to β-1 integrin reduction, costameric instability, and dilated cardiomyopathy.
Volume: 114
Issue: 30
Pages: E6250-E6259
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Publication
23266827 | J:195652
First Author: Manso AM
Year: 2013
Journal: J Biol Chem
Title: Talin1 has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload.
Volume: 288
Issue: 6
Pages: 4252-64
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Publication
23230271 | J:194413
First Author: Zou W
Year: 2013
Journal: Mol Cell Biol
Title: Talin1 and Rap1 are critical for osteoclast function.
Volume: 33
Issue: 4
Pages: 830-44
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Publication
2120593 | J:43417
First Author: Rees DJ
Year: 1990
Journal: Nature
Title: Sequence and domain structure of talin.
Volume: 347
Issue: 6294
Pages: 685-9
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Publication
15272303 | J:116247
First Author: Papagrigoriou E
Year: 2004
Journal: EMBO J
Title: Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle.
Volume: 23
Issue: 15
Pages: 2942-51
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Publication
15642262 | J:247412
First Author: Fillingham I
Year: 2005
Journal: Structure
Title: A vinculin binding domain from the talin rod unfolds to form a complex with the vinculin head.
Volume: 13
Issue: 1
Pages: 65-74
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Publication
20399778 | J:160366
First Author: Goult BT
Year: 2010
Journal: FEBS Lett
Title: The domain structure of talin: residues 1815-1973 form a five-helix bundle containing a cryptic vinculin-binding site.
Volume: 584
Issue: 11
Pages: 2237-41
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Publication
20150896 | J:158602
First Author: Goult BT
Year: 2010
Journal: EMBO J
Title: Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation.
Volume: 29
Issue: 6
Pages: 1069-80
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Publication
22210111 | J:245251
First Author: Moore DT
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Affinity of talin-1 for the β3-integrin cytosolic domain is modulated by its phospholipid bilayer environment.
Volume: 109
Issue: 3
Pages: 793-8
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Publication
20971947 | J:177971
First Author: Haling JR
Year: 2011
Journal: Blood
Title: Talin-dependent integrin activation is required for fibrin clot retraction by platelets.
Volume: 117
Issue: 5
Pages: 1719-22
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33157226 | J:306865
 
First Author: Al-Yafeai Z
Year: 2021
Journal: Matrix Biol
Title: Integrin affinity modulation critically regulates atherogenic endothelial activation in vitro and in vivo.
Volume: 96
Pages: 87-103
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22075696 | J:180412
First Author: Wernimont SA
Year: 2011
Journal: J Immunol
Title: Contact-dependent T cell activation and T cell stopping require talin1.
Volume: 187
Issue: 12
Pages: 6256-67
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28743899 | J:249694
First Author: Stegner D
Year: 2017
Journal: Nat Commun
Title: Thrombopoiesis is spatially regulated by the bone marrow vasculature.
Volume: 8
Issue: 1
Pages: 127
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18434420 | J:134979
First Author: Conti FJ
Year: 2008
Journal: Development
Title: Progressive myopathy and defects in the maintenance of myotendinous junctions in mice that lack talin 1 in skeletal muscle.
Volume: 135
Issue: 11
Pages: 2043-53
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24531545 | J:209643
First Author: Tian X
Year: 2014
Journal: J Clin Invest
Title: Podocyte-associated talin1 is critical for glomerular filtration barrier maintenance.
Volume: 124
Issue: 3
Pages: 1098-113
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32438408 | J:294933
 
First Author: Lim TJF
Year: 2020
Journal: J Exp Med
Title: Talin1 controls dendritic cell activation by regulating TLR complex assembly and signaling.
Volume: 217
Issue: 8
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18086864 | J:129708
First Author: Nieswandt B
Year: 2007
Journal: J Exp Med
Title: Loss of talin1 in platelets abrogates integrin activation, platelet aggregation, and thrombus formation in vitro and in vivo.
Volume: 204
Issue: 13
Pages: 3113-8
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30485809 | J:271017
First Author: Haage A
Year: 2018
Journal: Cell Rep
Title: Talin Autoinhibition Regulates Cell-ECM Adhesion Dynamics and Wound Healing In Vivo.
Volume: 25
Issue: 9
Pages: 2401-2416.e5
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17218263 | J:118784
First Author: Wegener KL
Year: 2007
Journal: Cell
Title: Structural basis of integrin activation by talin.
Volume: 128
Issue: 1
Pages: 171-82
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7635475 | J:27988
First Author: Gilmore AP
Year: 1995
Journal: Hum Genet
Title: Localisation of the human gene encoding the cytoskeletal protein talin to chromosome 9p.
Volume: 96
Issue: 2
Pages: 221-4
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9182713 | J:41000
 
First Author: Adey NB
Year: 1997
Journal: Biochem J
Title: Isolation of peptides from phage-displayed random peptide libraries that interact with the talin-binding domain of vinculin.
Volume: 324 ( Pt 2)
Pages: 523-8
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17430904 | J:122776
First Author: Moes M
Year: 2007
Journal: J Biol Chem
Title: The integrin binding site 2 (IBS2) in the talin rod domain is essential for linking integrin beta subunits to the cytoskeleton.
Volume: 282
Issue: 23
Pages: 17280-8
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27384267 | J:240780
 
First Author: Yao M
Year: 2016
Journal: Nat Commun
Title: The mechanical response of talin.
Volume: 7
Pages: 11966
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29170462 | J:256314
First Author: Zhu L
Year: 2017
Journal: Nat Commun
Title: Structure of Rap1b bound to talin reveals a pathway for triggering integrin activation.
Volume: 8
Issue: 1
Pages: 1744
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32518959 | J:301394
First Author: Lagarrigue F
Year: 2020
Journal: Blood
Title: Talin-1 is the principal platelet Rap1 effector of integrin activation.
Volume: 136
Issue: 10
Pages: 1180-1190
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30442677 | J:269782
First Author: Bromberger T
Year: 2018
Journal: Blood
Title: Direct Rap1/Talin1 interaction regulates platelet and neutrophil integrin activity in mice.
Volume: 132
Issue: 26
Pages: 2754-2762
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30420438 | J:268313
First Author: Lim TJF
Year: 2018
Journal: J Immunol
Title: Talin1 Methylation Is Required for Neutrophil Infiltration and Lipopolysaccharide-Induced Lethality.
Volume: 201
Issue: 12
Pages: 3651-3661
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20472831 | J:163495
First Author: Mace EM
Year: 2010
Journal: Blood
Title: Elucidation of the integrin LFA-1-mediated signaling pathway of actin polarization in natural killer cells.
Volume: 116
Issue: 8
Pages: 1272-9
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22306379 | J:316807
First Author: Praekelt U
Year: 2012
Journal: Eur J Cell Biol
Title: New isoform-specific monoclonal antibodies reveal different sub-cellular localisations for talin1 and talin2.
Volume: 91
Issue: 3
Pages: 180-91
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25465129 | J:245320
First Author: Chang YC
Year: 2014
Journal: Structure
Title: Structural and mechanistic insights into the recruitment of talin by RIAM in integrin signaling.
Volume: 22
Issue: 12
Pages: 1810-1820
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27150043 | J:245362
First Author: Zhang H
Year: 2016
Journal: Structure
Title: Structural and Functional Analysis of a Talin Triple-Domain Module Suggests an Alternative Talin Autoinhibitory Configuration.
Volume: 24
Issue: 5
Pages: 721-729
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21134644 | J:245286
First Author: Anthis NJ
Year: 2010
Journal: Structure
Title: Structural diversity in integrin/talin interactions.
Volume: 18
Issue: 12
Pages: 1654-66
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17202407 | J:123888
First Author: Lim J
Year: 2007
Journal: Mol Biol Cell
Title: An essential role for talin during alpha(M)beta(2)-mediated phagocytosis.
Volume: 18
Issue: 3
Pages: 976-85
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19124737 | J:143492
First Author: Mace EM
Year: 2009
Journal: J Immunol
Title: A dual role for talin in NK cell cytotoxicity: activation of LFA-1-mediated cell adhesion and polarization of NK cells.
Volume: 182
Issue: 2
Pages: 948-56
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22665520 | J:185189
First Author: Zhang F
Year: 2012
Journal: J Cell Biol
Title: Arginylation-dependent regulation of a proteolytic product of talin is essential for cell-cell adhesion.
Volume: 197
Issue: 6
Pages: 819-36
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22795696 | J:199768
First Author: Margadant C
Year: 2012
Journal: Curr Biol
Title: Distinct roles of talin and kindlin in regulating integrin α5β1 function and trafficking.
Volume: 22
Issue: 17
Pages: 1554-63
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26523364 | J:237578
First Author: Austen K
Year: 2015
Journal: Nat Cell Biol
Title: Extracellular rigidity sensing by talin isoform-specific mechanical linkages.
Volume: 17
Issue: 12
Pages: 1597-606
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29141864 | J:253408
First Author: Shiratori T
Year: 2018
Journal: J Immunol
Title: IL-1β Induces Pathologically Activated Osteoclasts Bearing Extremely High Levels of Resorbing Activity: A Possible Pathological Subpopulation of Osteoclasts, Accompanied by Suppressed Expression of Kindlin-3 and Talin-1.
Volume: 200
Issue: 1
Pages: 218-228
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31804547 | J:297892
First Author: Wang P
Year: 2019
Journal: Sci Rep
Title: Vinculins interaction with talin is essential for mammary epithelial differentiation.
Volume: 9
Issue: 1
Pages: 18400
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26905930 | J:319147
 
First Author: Lim D
Year: 2016
Journal: Immunol Lett
Title: Non-cleavable talin rescues defect in the T-cell conjugation of T-cells deficient in the immune adaptor SKAP1.
Volume: 172
Pages: 40-6
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12606711 | J:230357
First Author: Calderwood DA
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling.
Volume: 100
Issue: 5
Pages: 2272-7
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20610383 | J:240268
First Author: Gingras AR
Year: 2010
Journal: J Biol Chem
Title: Central region of talin has a unique fold that binds vinculin and actin.
Volume: 285
Issue: 38
Pages: 29577-87
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29703862 | J:263318
First Author: Klann JE
Year: 2018
Journal: J Immunol
Title: Integrin Activation Controls Regulatory T Cell-Mediated Peripheral Tolerance.
Volume: 200
Issue: 12
Pages: 4012-4023
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28515282 | J:247669
First Author: Klann JE
Year: 2017
Journal: J Immunol
Title: Talin Plays a Critical Role in the Maintenance of the Regulatory T Cell Pool.
Volume: 198
Issue: 12
Pages: 4639-4651
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16247034 | J:104522
First Author: Cluzel C
Year: 2005
Journal: J Cell Biol
Title: The mechanisms and dynamics of (alpha)v(beta)3 integrin clustering in living cells.
Volume: 171
Issue: 2
Pages: 383-92
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18792400 | J:141233
First Author: Cham CM
Year: 2008
Journal: Eur J Immunol
Title: Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells.
Volume: 38
Issue: 9
Pages: 2438-50
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18638481 | J:168870
First Author: Wegener KL
Year: 2008
Journal: J Mol Biol
Title: Structural basis for the interaction between the cytoplasmic domain of the hyaluronate receptor layilin and the talin F3 subdomain.
Volume: 382
Issue: 1
Pages: 112-26
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23071154 | J:193930
First Author: Wang S
Year: 2012
Journal: J Cell Biol
Title: Tiam1 interaction with the PAR complex promotes talin-mediated Rac1 activation during polarized cell migration.
Volume: 199
Issue: 2
Pages: 331-45
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26634421 | J:228315
 
First Author: Atherton P
Year: 2015
Journal: Nat Commun
Title: Vinculin controls talin engagement with the actomyosin machinery.
Volume: 6
Pages: 10038
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23389036 | J:203509
First Author: Goult BT
Year: 2013
Journal: J Biol Chem
Title: RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover.
Volume: 288
Issue: 12
Pages: 8238-49
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26169939 | J:226439
First Author: Yago T
Year: 2015
Journal: J Exp Med
Title: Blocking neutrophil integrin activation prevents ischemia-reperfusion injury.
Volume: 212
Issue: 8
Pages: 1267-81
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Publication
30242097 | J:322715
First Author: Lagarrigue F
Year: 2018
Journal: Blood Adv
Title: Rap1 binding to the talin 1 F0 domain makes a minimal contribution to murine platelet GPIIb-IIIa activation.
Volume: 2
Issue: 18
Pages: 2358-2368
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26438512 | J:229952
First Author: Klapproth S
Year: 2015
Journal: Blood
Title: Minimal amounts of kindlin-3 suffice for basal platelet and leukocyte functions in mice.
Volume: 126
Issue: 24
Pages: 2592-600
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26337492 | J:229954
First Author: Klapproth S
Year: 2015
Journal: Blood
Title: Loss of the Rap1 effector RIAM results in leukocyte adhesion deficiency due to impaired β2 integrin function in mice.
Volume: 126
Issue: 25
Pages: 2704-12
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18188447 | J:131289
First Author: Wang Y
Year: 2008
Journal: J Clin Invest
Title: Loss of PIP5KIgamma, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes.
Volume: 118
Issue: 2
Pages: 812-9
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27760339 | J:259939
First Author: Meli AP
Year: 2016
Journal: Immunity
Title: The Integrin LFA-1 Controls T Follicular Helper Cell Generation and Maintenance.
Volume: 45
Issue: 4
Pages: 831-846
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20923969 | J:167382
First Author: Manevich-Mendelson E
Year: 2010
Journal: Blood
Title: Talin1 is required for integrin-dependent B lymphocyte homing to lymph nodes and the bone marrow but not for follicular B-cell maturation in the spleen.
Volume: 116
Issue: 26
Pages: 5907-18
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28157452 | J:260512
First Author: Wilson ZS
Year: 2017
Journal: Am J Respir Cell Mol Biol
Title: Activated β2 Integrins Restrict Neutrophil Recruitment during Murine Acute Pseudomonal Pneumonia.
Volume: 56
Issue: 5
Pages: 620-627
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24162846 | J:206751
First Author: Shen B
Year: 2013
Journal: Nature
Title: A directional switch of integrin signalling and a new anti-thrombotic strategy.
Volume: 503
Issue: 7474
Pages: 131-5
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30131434 | J:269939
First Author: Stefanini L
Year: 2018
Journal: Blood
Title: Functional redundancy between RAP1 isoforms in murine platelet production and function.
Volume: 132
Issue: 18
Pages: 1951-1962
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32238906 | J:297988
First Author: Liu Y
Year: 2020
Journal: Lab Invest
Title: Increased talin-vinculin spatial proximities in livers in response to spotted fever group rickettsial and Ebola virus infections.
Volume: 100
Issue: 8
Pages: 1030-1041
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25751747 | J:231641
First Author: Gunawan M
Year: 2015
Journal: Nat Immunol
Title: The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin.
Volume: 16
Issue: 5
Pages: 505-16
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30707047 | J:294962
First Author: Pulous FE
Year: 2019
Journal: Circ Res
Title: Talin-Dependent Integrin Activation Regulates VE-Cadherin Localization and Endothelial Cell Barrier Function.
Volume: 124
Issue: 6
Pages: 891-903
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Publication
37903776 | J:342233
First Author: Hou X
Year: 2023
Journal: Cell Death Dis
Title: Talin-1 inhibits Smurf1-mediated Stat3 degradation to modulate β-cell proliferation and mass in mice.
Volume: 14
Issue: 10
Pages: 709
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18278053 | J:133659
First Author: Moser M
Year: 2008
Journal: Nat Med
Title: Kindlin-3 is essential for integrin activation and platelet aggregation.
Volume: 14
Issue: 3
Pages: 325-30
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24585775 | J:210743
First Author: Stefanini L
Year: 2014
Journal: Blood
Title: A talin mutant that impairs talin-integrin binding in platelets decelerates αIIbβ3 activation without pathological bleeding.
Volume: 123
Issue: 17
Pages: 2722-31
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26821125 | J:230650
 
First Author: Theodosiou M
Year: 2016
Journal: Elife
Title: Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin.
Volume: 5
Pages: e10130
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22431571 | J:185175
First Author: Lefort CT
Year: 2012
Journal: Blood
Title: Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation.
Volume: 119
Issue: 18
Pages: 4275-82
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31826978 | J:283554
 
First Author: Lee RH
Year: 2019
Journal: Sci Transl Med
Title: Impaired hemostatic activity of healthy transfused platelets in inherited and acquired platelet disorders: Mechanisms and implications.
Volume: 11
Issue: 522
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25795918 | J:224116
First Author: Lorenz V
Year: 2015
Journal: Blood
Title: Targeted downregulation of platelet CLEC-2 occurs through Syk-independent internalization.
Volume: 125
Issue: 26
Pages: 4069-77
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12867986 | J:84472
First Author: Jiang G
Year: 2003
Journal: Nature
Title: Two-piconewton slip bond between fibronectin and the cytoskeleton depends on talin.
Volume: 424
Issue: 6946
Pages: 334-7
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20308429 | J:200373
First Author: Pasapera AM
Year: 2010
Journal: J Cell Biol
Title: Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation.
Volume: 188
Issue: 6
Pages: 877-90
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Publication
21947080 | J:180707
First Author: Rantala JK
Year: 2011
Journal: Nat Cell Biol
Title: SHARPIN is an endogenous inhibitor of β1-integrin activation.
Volume: 13
Issue: 11
Pages: 1315-24
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16000373 | J:104081
First Author: Gallant ND
Year: 2005
Journal: Mol Biol Cell
Title: Cell adhesion strengthening: contributions of adhesive area, integrin binding, and focal adhesion assembly.
Volume: 16
Issue: 9
Pages: 4329-40
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18216331 | J:131855
First Author: Parsons M
Year: 2008
Journal: J Cell Sci
Title: Quantification of integrin receptor agonism by fluorescence lifetime imaging.
Volume: 121
Issue: Pt 3
Pages: 265-71
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21670148 | J:175092
First Author: Liu J
Year: 2011
Journal: Mol Cell Biol
Title: Talin1 regulates integrin turnover to promote embryonic epithelial morphogenesis.
Volume: 31
Issue: 16
Pages: 3366-77
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27043085 | J:236640
First Author: Nader GP
Year: 2016
Journal: Nat Cell Biol
Title: FAK, talin and PIPKIγ regulate endocytosed integrin activation to polarize focal adhesion assembly.
Volume: 18
Issue: 5
Pages: 491-503
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11807098 | J:80557
First Author: van der Flier A
Year: 2002
Journal: J Cell Biol
Title: Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits.
Volume: 156
Issue: 2
Pages: 361-76
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11381084 | J:69803
First Author: Palmer S
Year: 2001
Journal: J Cell Biol
Title: The small muscle-specific protein Csl modifies cell shape and promotes myocyte fusion in an insulin-like growth factor 1-dependent manner.
Volume: 153
Issue: 5
Pages: 985-98
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28993400 | J:248183
First Author: Mathew S
Year: 2017
Journal: Development
Title: Talin regulates integrin β1-dependent and -independent cell functions in ureteric bud development.
Volume: 144
Issue: 22
Pages: 4148-4158
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Publication
35197328 | J:322712
First Author: Lagarrigue F
Year: 2022
Journal: J Immunol
Title: Direct Binding of Rap1 to Talin1 and to MRL Proteins Promotes Integrin Activation in CD4+ T Cells.
Volume: 208
Issue: 6
Pages: 1378-1388
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Publication
32580934 | J:295480
 
First Author: Haage A
Year: 2020
Journal: Development
Title: Precise coordination of cell-ECM adhesion is essential for efficient melanoblast migration during development.
Volume: 147
Issue: 14
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Publication
31048328 | J:276472
First Author: Zhang N
Year: 2019
Journal: J Exp Med
Title: Expression of factor V by resident macrophages boosts host defense in the peritoneal cavity.
Volume: 216
Issue: 6
Pages: 1291-1300
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Publication
37598341 | J:341186
First Author: Sun H
Year: 2023
Journal: Cell Rep
Title: IL-2 can signal via chemokine receptors to promote regulatory T cells' suppressive function.
Volume: 42
Issue: 8
Pages: 112996
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