Chondroitin sulfate proteoglycan 5 (CSPG5), also known as Neuroglycan C or NGC, is a transmembrane chondroitin sulfate proteoglycan that promotes neurite outgrowth []. It has been shown to interacts with pleiotrophin, a heparin-binding growth factor []. Overexpression of NGC has been shown to enhance neuron dendritic branching and increases the complexity of dendritic spines and filopodia [].