|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 301 to 400 out of 409 for Tlx3

0.037s
Type Details Score
Publication
First Author: Storm R
Year: 2009
Journal: Development
Title: The bHLH transcription factor Olig3 marks the dorsal neuroepithelium of the hindbrain and is essential for the development of brainstem nuclei.
Volume: 136
Issue: 2
Pages: 295-305
Publication
First Author: Zechner D
Year: 2007
Journal: Dev Biol
Title: Bmp and Wnt/beta-catenin signals control expression of the transcription factor Olig3 and the specification of spinal cord neurons.
Volume: 303
Issue: 1
Pages: 181-90
Publication
First Author: Kriks S
Year: 2005
Journal: Development
Title: Gsh2 is required for the repression of Ngn1 and specification of dorsal interneuron fate in the spinal cord.
Volume: 132
Issue: 13
Pages: 2991-3002
Publication
First Author: Bröhl D
Year: 2008
Journal: Dev Biol
Title: A transcriptional network coordinately determines transmitter and peptidergic fate in the dorsal spinal cord.
Volume: 322
Issue: 2
Pages: 381-93
Publication
First Author: Stolt CC
Year: 2006
Journal: Dev Cell
Title: SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function.
Volume: 11
Issue: 5
Pages: 697-709
Publication
First Author: Gray de Cristoforis A
Year: 2020
Journal: Mol Brain
Title: Differentiation and localization of interneurons in the developing spinal cord depends on DOT1L expression.
Volume: 13
Issue: 1
Pages: 85
Publication
First Author: Jacob J
Year: 2009
Journal: Development
Title: Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the vertebrate hindbrain.
Volume: 136
Issue: 14
Pages: 2477-85
Publication    
First Author: Chang SH
Year: 2021
Journal: Elife
Title: MicroRNAs mediate precise control of spinal interneuron populations to exert delicate sensory-to-motor outputs.
Volume: 10
Publication
First Author: Ding YQ
Year: 2004
Journal: Development
Title: Lmx1b controls the differentiation and migration of the superficial dorsal horn neurons of the spinal cord.
Volume: 131
Issue: 15
Pages: 3693-703
Publication
First Author: Desiderio S
Year: 2019
Journal: Cell Rep
Title: Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA.
Volume: 26
Issue: 13
Pages: 3522-3536.e5
Publication
First Author: Vermeiren S
Year: 2023
Journal: iScience
Title: Prdm12 represses the expression of the visceral neuron determinants Phox2a/b in developing somatosensory ganglia.
Volume: 26
Issue: 12
Pages: 108364
Publication
First Author: Hu J
Year: 2012
Journal: J Neurosci
Title: c-Maf is required for the development of dorsal horn laminae III/IV neurons and mechanoreceptive DRG axon projections.
Volume: 32
Issue: 16
Pages: 5362-73
Publication
First Author: Roome RB
Year: 2020
Journal: Cell Rep
Title: Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans.
Volume: 33
Issue: 8
Pages: 108425
Publication
First Author: Lu CC
Year: 2011
Journal: J Neurosci
Title: Developmental profiling of spiral ganglion neurons reveals insights into auditory circuit assembly.
Volume: 31
Issue: 30
Pages: 10903-18
Publication
First Author: Tulloch AJ
Year: 2019
Journal: J Comp Neurol
Title: Diverse spinal commissural neuron populations revealed by fate mapping and molecular profiling using a novel Robo3Cre mouse.
Volume: 527
Issue: 18
Pages: 2948-2972
Publication
First Author: Shi M
Year: 2012
Journal: J Cell Sci
Title: Notch-Rbpj signaling is required for the development of noradrenergic neurons in the mouse locus coeruleus.
Volume: 125
Issue: Pt 18
Pages: 4320-32
Publication
First Author: Ohayon D
Year: 2016
Journal: Cell Rep
Title: Onset of Spinal Cord Astrocyte Precursor Emigration from the Ventricular Zone Involves the Zeb1 Transcription Factor.
Volume: 17
Issue: 6
Pages: 1473-1481
Publication
First Author: Morello F
Year: 2020
Journal: Cell Rep
Title: Molecular Fingerprint and Developmental Regulation of the Tegmental GABAergic and Glutamatergic Neurons Derived from the Anterior Hindbrain.
Volume: 33
Issue: 2
Pages: 108268
Publication
First Author: Zhang Q
Year: 2018
Journal: Cell Death Dis
Title: Temporal requirements for ISL1 in sympathetic neuron proliferation, differentiation, and diversification.
Volume: 9
Issue: 2
Pages: 247
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Memic F
Year: 2018
Journal: Gastroenterology
Title: Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.
Volume: 154
Issue: 3
Pages: 624-636
Publication
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Publication
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
GXD Expression
Probe: MGI:7388596
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3667828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7388620
Age: postnatal day 30
Image: 1E
Note: Co-expression with Tlx3 in 99% of neurons.
Specimen Label: 1E
Detected: true
Specimen Num: 1
HT Experiment
Series Id: GSE82097
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
GXD Expression  
Probe: MGI:7388605
Assay Type: RNA in situ
Annotation Date: 2022-12-02
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3667828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7388627
Age: postnatal day 30
Note: Expression in17% of IB4-positive neurons.
Specimen Label: not shown PBX3 Tlx3 CKO
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:7388609
Assay Type: RNA in situ
Annotation Date: 2022-12-02
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3667728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7388630
Age: postnatal day 30
Note: Expression in thoracic DGG greatly reduced but not compltely eliminated.
Specimen Label: Tlx3 CKO thoracic DRG not shown
Detected: true
Specimen Num: 3
Allele
Name: T cell leukemia, homeobox 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Allele
Name: transgene insertion PL58, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Recombinase
Allele
Name: transgene insertion PL56, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Recombinase
Publication
First Author: King B
Year: 2012
Journal: Cancer Cell
Title: Hijacking T cell differentiation: new insights in TLX function in T-ALL.
Volume: 21
Issue: 4
Pages: 453-5
Strain
Attribute String: transgenic, mutant stock
Strain
Attribute String: congenic, mutant strain, transgenic
Strain
Attribute String: transgenic, mutant stock
Publication
First Author: Shinotsuka T
Year: 2023
Journal: J Neurosci
Title: Layer 5 Intratelencephalic Neurons in the Motor Cortex Stably Encode Skilled Movement.
Volume: 43
Issue: 43
Pages: 7130-7148
Publication
First Author: Shimizu H
Year: 2000
Journal: FEBS Lett
Title: Identification of an optimal Ncx binding sequence required for transcriptional activation.
Volume: 475
Issue: 3
Pages: 170-4
Publication
First Author: Kato Y
Year: 2009
Journal: Pediatr Surg Int
Title: Immature enteric neurons in Ncx/Hox11L.1 deficient intestinal neuronal dysplasia model mice.
Volume: 25
Issue: 11
Pages: 961-5
Publication
First Author: Koehler K
Year: 2000
Journal: Dev Dyn
Title: Hox11 is required to maintain normal Wt1 mRNA levels in the developing spleen.
Volume: 218
Issue: 1
Pages: 201-6
Protein Domain
Type: Family
Description: This entry represents a group of homeobox proteins, including Tlx1/2/3. They are transcription factors that belong to the to the Hox11 family. In general, they bind to the DNA sequence 5'-CGGTAATTGG-3' []. Tlx1 and Tlx3 are required for fate determination of glutamatergic and GABAergic neurons in the dorsal spinal cord [, ]. Tlx1, also known as Hox11, is required to maintain normal Wt1 mRNA levels in the developing spleen in mice []. Tlx2, also known as Ncx/Hox11L.1, is required for the adequate development of enteric neurons in mice [].
Publication
First Author: Bender PTR
Year: 2023
Journal: Cell Rep
Title: Synaptic zinc potentiates AMPA receptor function in mouse auditory cortex.
Volume: 42
Issue: 8
Pages: 112932
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Tlx3-cre)PL56Gsat/?
Background: involves: 129S4/SvJaeSor * FVB/N
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Chang JC
Year: 2013
Journal: Dev Cell
Title: Prdm13 mediates the balance of inhibitory and excitatory neurons in somatosensory circuits.
Volume: 25
Issue: 2
Pages: 182-95
Publication
First Author: Smits WK
Year: 2023
Journal: Cell Rep
Title: Elevated enhancer-oncogene contacts and higher oncogene expression levels by recurrent CTCF inactivating mutations in acute T cell leukemia.
Volume: 42
Issue: 4
Pages: 112373
Publication
First Author: Vanden Bempt M
Year: 2018
Journal: Cancer Cell
Title: Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia.
Volume: 34
Issue: 2
Pages: 271-285.e7
Publication
First Author: Della Gatta G
Year: 2012
Journal: Nat Med
Title: Reverse engineering of TLX oncogenic transcriptional networks identifies RUNX1 as tumor suppressor in T-ALL.
Volume: 18
Issue: 3
Pages: 436-40
Publication
First Author: Dadi S
Year: 2012
Journal: Cancer Cell
Title: TLX homeodomain oncogenes mediate T cell maturation arrest in T-ALL via interaction with ETS1 and suppression of TCRα gene expression.
Volume: 21
Issue: 4
Pages: 563-76
Publication
First Author: Kim EJ
Year: 2015
Journal: Neuron
Title: Three Types of Cortical Layer 5 Neurons That Differ in Brain-wide Connectivity and Function.
Volume: 88
Issue: 6
Pages: 1253-67
Publication      
First Author: Kim EJ
Year: 2016
Journal: Cell Rep
Title: Improved Monosynaptic Neural Circuit Tracing Using Engineered Rabies Virus Glycoproteins.
Publication
First Author: Kim EJ
Year: 2020
Journal: Neuron
Title: Extraction of Distinct Neuronal Cell Types from within a Genetically Continuous Population.
Volume: 107
Issue: 2
Pages: 274-282.e6
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Tlx3-cre)PL56Gsat/?
Background: involves: 129 * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Candelas M
Year: 2019
Journal: Sci Rep
Title: Cav3.2 T-type calcium channels shape electrical firing in mouse Lamina II neurons.
Volume: 9
Issue: 1
Pages: 3112
Publication
First Author: Tran-Van-Minh A
Year: 2023
Journal: PLoS One
Title: Quantitative analysis of rabies virus-based synaptic connectivity tracing.
Volume: 18
Issue: 3
Pages: e0278053
Publication
First Author: Hooks BM
Year: 2018
Journal: Nat Commun
Title: Topographic precision in sensory and motor corticostriatal projections varies across cell type and cortical area.
Volume: 9
Issue: 1
Pages: 3549
Publication
First Author: Takahashi N
Year: 2020
Journal: Nat Neurosci
Title: Active dendritic currents gate descending cortical outputs in perception.
Volume: 23
Issue: 10
Pages: 1277-1285
Publication
First Author: FiÅŸek M
Year: 2023
Journal: Nature
Title: Cortico-cortical feedback engages active dendrites in visual cortex.
Volume: 617
Issue: 7962
Pages: 769-776
Publication
First Author: Smith JB
Year: 2016
Journal: Neuron
Title: Genetic-Based Dissection Unveils the Inputs and Outputs of Striatal Patch and Matrix Compartments.
Volume: 91
Issue: 5
Pages: 1069-1084
Publication
First Author: Sun Y
Year: 2022
Journal: Cell Rep
Title: Single-cell transcriptomic landscapes of the otic neuronal lineage at multiple early embryonic ages.
Volume: 38
Issue: 12
Pages: 110542
Publication
First Author: Narayanan DP
Year: 2023
Journal: Cereb Cortex
Title: Biological constraints on stereotaxic targeting of functionally-defined cortical areas.
Volume: 33
Issue: 6
Pages: 3293-3310
Publication    
First Author: Yamawaki N
Year: 2021
Journal: Elife
Title: Circuit organization of the excitatory sensorimotor loop through hand/forelimb S1 and M1.
Volume: 10
Publication
First Author: Wester JC
Year: 2019
Journal: Neuron
Title: Neocortical Projection Neurons Instruct Inhibitory Interneuron Circuit Development in a Lineage-Dependent Manner.
Volume: 102
Issue: 5
Pages: 960-975.e6
Publication
First Author: Pancani T
Year: 2023
Journal: Nat Commun
Title: Cholinergic deficits selectively boost cortical intratelencephalic control of striatum in male Huntington's disease model mice.
Volume: 14
Issue: 1
Pages: 1398
Publication    
First Author: Hage TA
Year: 2022
Journal: Elife
Title: Synaptic connectivity to L2/3 of primary visual cortex measured by two-photon optogenetic stimulation.
Volume: 11
Publication
First Author: Bharioke A
Year: 2022
Journal: Neuron
Title: General anesthesia globally synchronizes activity selectively in layer 5 cortical pyramidal neurons.
Volume: 110
Issue: 12
Pages: 2024-2040.e10
Publication
First Author: Li N
Year: 2015
Journal: Nature
Title: A motor cortex circuit for motor planning and movement.
Volume: 519
Issue: 7541
Pages: 51-6
Publication
First Author: Heindorf M
Year: 2018
Journal: Neuron
Title: Mouse Motor Cortex Coordinates the Behavioral Response to Unpredicted Sensory Feedback.
Volume: 99
Issue: 5
Pages: 1040-1054.e5
Publication
First Author: Li N
Year: 2016
Journal: Nature
Title: Robust neuronal dynamics in premotor cortex during motor planning.
Volume: 532
Issue: 7600
Pages: 459-64
Protein
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 291  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 332  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 333  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 213  
Fragment?: false
Publication
First Author: de Vries SEJ
Year: 2020
Journal: Nat Neurosci
Title: A large-scale standardized physiological survey reveals functional organization of the mouse visual cortex.
Volume: 23
Issue: 1
Pages: 138-151
Publication
First Author: Abecassis ZA
Year: 2020
Journal: J Neurosci
Title: Npas1(+)-Nkx2.1(+) Neurons Are an Integral Part of the Cortico-pallido-cortical Loop.
Volume: 40
Issue: 4
Pages: 743-768
Publication
First Author: Zolnik TA
Year: 2020
Journal: Cell Rep
Title: Layer 6b Is Driven by Intracortical Long-Range Projection Neurons.
Volume: 30
Issue: 10
Pages: 3492-3505.e5
Publication
First Author: Gerfen CR
Year: 2013
Journal: Neuron
Title: GENSAT BAC cre-recombinase driver lines to study the functional organization of cerebral cortical and basal ganglia circuits.
Volume: 80
Issue: 6
Pages: 1368-83
Publication
First Author: Gouwens NW
Year: 2020
Journal: Cell
Title: Integrated Morphoelectric and Transcriptomic Classification of Cortical GABAergic Cells.
Volume: 183
Issue: 4
Pages: 935-953.e19