|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 501 to 600 out of 722 for Rptor

<< First    < Previous  |  Next >    Last >>
0.041s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Publication
37694145 | J:341110
First Author: Cortada M
Year: 2023
Journal: iScience
Title: mTORC2 regulates auditory hair cell structure and function.
Volume: 26
Issue: 9
Pages: 107687
•
•
•
•
•
Publication
20543991 | J:161591
First Author: Siuta MA
Year: 2010
Journal: PLoS Biol
Title: Dysregulation of the norepinephrine transporter sustains cortical hypodopaminergia and schizophrenia-like behaviors in neuronal rictor null mice.
Volume: 8
Issue: 6
Pages: e1000393
•
•
•
•
•
Publication
25196701 | J:218063
First Author: Chen J
Year: 2015
Journal: J Bone Miner Res
Title: mTORC2 signaling promotes skeletal growth and bone formation in mice.
Volume: 30
Issue: 2
Pages: 369-78
•
•
•
•
•
Publication
29099279 | J:333874
First Author: Liang Z
Year: 2018
Journal: Autophagy
Title: MTOR signaling is essential for the development of thymic epithelial cells and the induction of central immune tolerance.
Volume: 14
Issue: 3
Pages: 505-517
•
•
•
•
•
Publication
34541875 | J:311577
     
First Author: Castro E
Year: 2021
Journal: Am J Physiol Endocrinol Metab
Title: Adipocyte-specific mTORC2 deficiency impairs BAT and iWAT thermogenic capacity without affecting glucose uptake and energy expenditure in cold-acclimated mice.
•
•
•
•
•
Publication
20620941 | J:161995
First Author: Lee K
Year: 2010
Journal: Immunity
Title: Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways.
Volume: 32
Issue: 6
Pages: 743-53
•
•
•
•
•
Publication
22473959 | J:183849
First Author: Lee K
Year: 2012
Journal: J Exp Med
Title: Vital roles of mTOR complex 2 in Notch-driven thymocyte differentiation and leukemia.
Volume: 209
Issue: 4
Pages: 713-28
•
•
•
•
•
Publication
26635098 | J:250146
 
First Author: Aimi F
Year: 2015
Journal: Sci Rep
Title: Endothelial Rictor is crucial for midgestational development and sustained and extensive FGF2-induced neovascularization in the adult.
Volume: 5
Pages: 17705
•
•
•
•
•
Publication
19497867 | J:150064
First Author: Cybulski N
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: mTOR complex 2 in adipose tissue negatively controls whole-body growth.
Volume: 106
Issue: 24
Pages: 9902-7
•
•
•
•
•
Publication
26772600 | J:239970
First Author: Albert V
Year: 2016
Journal: EMBO Mol Med
Title: mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue.
Volume: 8
Issue: 3
Pages: 232-46
•
•
•
•
•
Publication
20332342 | J:169357
First Author: Kumar A
Year: 2010
Journal: Diabetes
Title: Fat cell-specific ablation of rictor in mice impairs insulin-regulated fat cell and whole-body glucose and lipid metabolism.
Volume: 59
Issue: 6
Pages: 1397-406
•
•
•
•
•
Publication
32905798 | J:296626
First Author: Kim CS
Year: 2020
Journal: Cell Metab
Title: Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle.
Volume: 32
Issue: 4
Pages: 629-642.e8
•
•
•
•
•
Publication
17043309 | J:113443
First Author: Yang Q
Year: 2006
Journal: Genes Dev
Title: Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity.
Volume: 20
Issue: 20
Pages: 2820-32
•
•
•
•
•
Publication
25843706 | J:228164
First Author: Sciarretta S
Year: 2015
Journal: Cell Rep
Title: mTORC2 regulates cardiac response to stress by inhibiting MST1.
Volume: 11
Issue: 1
Pages: 125-36
•
•
•
•
•
Publication
28821013 | J:246111
First Author: Huang L
Year: 2017
Journal: PLoS Biol
Title: Rictor positively regulates B cell receptor signaling by modulating actin reorganization via ezrin.
Volume: 15
Issue: 8
Pages: e2001750
•
•
•
•
•
Publication
27016480 | J:234861
First Author: Drägert K
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Basal mTORC2 activity and expression of its components display diurnal variation in mouse perivascular adipose tissue.
Volume: 473
Issue: 1
Pages: 317-322
•
•
•
•
•
Publication
28694518 | J:270960
First Author: Hu T
Year: 2017
Journal: Sci Rep
Title: PDK1 plays a vital role on hematopoietic stem cell function.
Volume: 7
Issue: 1
Pages: 4943
•
•
•
•
•
Publication
23049074 | J:191137
First Author: Carson RP
Year: 2013
Journal: Hum Mol Genet
Title: Deletion of Rictor in neural progenitor cells reveals contributions of mTORC2 signaling to tuberous sclerosis complex.
Volume: 22
Issue: 1
Pages: 140-52
•
•
•
•
•
Publication
23030823 | J:190940
First Author: Najafov A
Year: 2012
Journal: Biochem J
Title: Akt is efficiently activated by PIF-pocket- and PtdIns(3,4,5)P3-dependent mechanisms leading to resistance to PDK1 inhibitors.
Volume: 448
Issue: 2
Pages: 285-95
•
•
•
•
•
Publication
27225119 | J:235750
First Author: Zhou F
Year: 2016
Journal: Nature
Title: Tracing haematopoietic stem cell formation at single-cell resolution.
Volume: 533
Issue: 7604
Pages: 487-92
•
•
•
•
•
Publication
31668132 | J:294138
First Author: Wang H
Year: 2019
Journal: Virulence
Title: T-cell-specific mTOR deletion in mice ameliorated CD4+ T-cell survival in lethal sepsis induced by severe invasive candidiasis.
Volume: 10
Issue: 1
Pages: 892-901
•
•
•
•
•
Publication
37738689 | J:344268
First Author: Guo R
Year: 2023
Journal: Int Immunopharmacol
Title: Depletion of mTOR ameliorates CD(4)(+) T cell pyroptosis by promoting autophagy activity in septic mice.
Volume: 124
Issue: Pt B
Pages: 110964
•
•
•
•
•
Publication
26598511 | J:252582
First Author: Shende P
Year: 2016
Journal: Cardiovasc Res
Title: Cardiac mTOR complex 2 preserves ventricular function in pressure-overload hypertrophy.
Volume: 109
Issue: 1
Pages: 103-14
•
•
•
•
•
Publication
29161318 | J:251217
First Author: Grier MD
Year: 2017
Journal: PLoS One
Title: Loss of mTORC2 signaling in oligodendrocyte precursor cells delays myelination.
Volume: 12
Issue: 11
Pages: e0188417
•
•
•
•
•
Allele
Rptor<em1Smoc> | MGI:7292121
Name: regulatory associated protein of MTOR, complex 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
•
•
•
•
•
Publication
24740015 | J:215205
First Author: Festuccia WT
Year: 2014
Journal: PLoS One
Title: Myeloid-specific Rictor deletion induces M1 macrophage polarization and potentiates in vivo pro-inflammatory response to lipopolysaccharide.
Volume: 9
Issue: 4
Pages: e95432
•
•
•
•
•
Publication
24705297 | J:209960
First Author: Heikamp EB
Year: 2014
Journal: Nat Immunol
Title: The AGC kinase SGK1 regulates TH1 and TH2 differentiation downstream of the mTORC2 complex.
Volume: 15
Issue: 5
Pages: 457-64
•
•
•
•
•
Publication
28078715 | J:246561
First Author: Sklarz T
Year: 2017
Journal: Eur J Immunol
Title: mTORC2 regulates multiple aspects of NKT-cell development and function.
Volume: 47
Issue: 3
Pages: 516-526
•
•
•
•
•
Publication
33027655 | J:304671
First Author: Hsiao WY
Year: 2020
Journal: Cell Rep
Title: The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development.
Volume: 33
Issue: 1
Pages: 108223
•
•
•
•
•
Publication
27098609 | J:236883
 
First Author: Tang Y
Year: 2016
Journal: Nat Commun
Title: Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism.
Volume: 7
Pages: 11365
•
•
•
•
•
Publication
24662050 | J:215360
First Author: Zhao X
Year: 2014
Journal: Mol Cell Biol
Title: Phosphoinositide-dependent kinase 1 and mTORC2 synergistically maintain postnatal heart growth and heart function in mice.
Volume: 34
Issue: 11
Pages: 1966-75
•
•
•
•
•
Publication
25559258 | J:259466
First Author: Shrestha S
Year: 2015
Journal: Nat Immunol
Title: Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses.
Volume: 16
Issue: 2
Pages: 178-87
•
•
•
•
•
Publication
25564616 | J:244133
First Author: Chen Z
Year: 2015
Journal: J Biol Chem
Title: Rictor/mTORC2 pathway in oocytes regulates folliculogenesis, and its inactivation causes premature ovarian failure.
Volume: 290
Issue: 10
Pages: 6387-96
•
•
•
•
•
Publication
26833095 | J:254440
 
First Author: Wu T
Year: 2016
Journal: Sci Rep
Title: mTOR masters monocytic myeloid-derived suppressor cells in mice with allografts or tumors.
Volume: 6
Pages: 20250
•
•
•
•
•
Publication
28128208 | J:244249
 
First Author: Hallowell RW
Year: 2017
Journal: Nat Commun
Title: mTORC2 signalling regulates M2 macrophage differentiation in response to helminth infection and adaptive thermogenesis.
Volume: 8
Pages: 14208
•
•
•
•
•
Publication
25740823 | J:220234
First Author: Carr TD
Year: 2015
Journal: Carcinogenesis
Title: Conditional disruption of rictor demonstrates a direct requirement for mTORC2 in skin tumor development and continued growth of established tumors.
Volume: 36
Issue: 4
Pages: 487-97
•
•
•
•
•
Publication
23958952 | J:203260
First Author: Lee K
Year: 2013
Journal: Blood
Title: Requirement for Rictor in homeostasis and function of mature B lymphoid cells.
Volume: 122
Issue: 14
Pages: 2369-79
•
•
•
•
•
Publication
33388318 | J:314686
First Author: Zhao Y
Year: 2021
Journal: Gastroenterology
Title: mTORC1 and mTORC2 Converge on the Arp2/3 Complex to Promote KrasG12D-Induced Acinar-to-Ductal Metaplasia and Early Pancreatic Carcinogenesis.
Volume: 160
Issue: 5
Pages: 1755-1770.e17
•
•
•
•
•
Allele
Rictor<+> | MGI:3845877
 
Name: RPTOR independent companion of MTOR, complex 2; wild type
Allele Type: Not Specified
•
•
•
•
•
Publication
22521878 | J:184605
First Author: Hagiwara A
Year: 2012
Journal: Cell Metab
Title: Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c.
Volume: 15
Issue: 5
Pages: 725-38
•
•
•
•
•
Publication
34784501 | J:321718
First Author: Gerlach BD
Year: 2021
Journal: Cell Metab
Title: Efferocytosis induces macrophage proliferation to help resolve tissue injury.
Volume: 33
Issue: 12
Pages: 2445-2463.e8
•
•
•
•
•
Publication
25059582 | J:215384
First Author: Lamming DW
Year: 2014
Journal: Aging Cell
Title: Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan.
Volume: 13
Issue: 5
Pages: 911-7
•
•
•
•
•
Publication
21765414 | J:176473
First Author: Yang K
Year: 2011
Journal: Nat Immunol
Title: The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function.
Volume: 12
Issue: 9
Pages: 888-97
•
•
•
•
•
Publication
27690224 | J:238500
   
First Author: Yang J
Year: 2016
Journal: Elife
Title: Critical roles of mTOR Complex 1 and 2 for T follicular helper cell differentiation and germinal center responses.
Volume: 5
•
•
•
•
•
Publication
25893604 | J:222700
First Author: Pollizzi KN
Year: 2015
Journal: J Clin Invest
Title: mTORC1 and mTORC2 selectively regulate CD8⁺ T cell differentiation.
Volume: 125
Issue: 5
Pages: 2090-108
•
•
•
•
•
Publication
29988091 | J:282530
First Author: Newton RH
Year: 2018
Journal: Nat Immunol
Title: Maintenance of CD4 T cell fitness through regulation of Foxo1.
Volume: 19
Issue: 8
Pages: 838-848
•
•
•
•
•
Publication
29425506 | J:271571
First Author: Menk AV
Year: 2018
Journal: Cell Rep
Title: Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions.
Volume: 22
Issue: 6
Pages: 1509-1521
•
•
•
•
•
Publication
24056770 | J:202319
First Author: Canaud G
Year: 2013
Journal: Nat Med
Title: AKT2 is essential to maintain podocyte viability and function during chronic kidney disease.
Volume: 19
Issue: 10
Pages: 1288-96
•
•
•
•
•
Publication
36456551 | J:335152
First Author: Werlen G
Year: 2022
Journal: Nat Commun
Title: Dietary glucosamine overcomes the defects in αβ-T cell ontogeny caused by the loss of de novo hexosamine biosynthesis.
Volume: 13
Issue: 1
Pages: 7404
•
•
•
•
•
Publication
22674026 | J:188431
First Author: Armour EA
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Cystogenesis and elongated primary cilia in Tsc1-deficient distal convoluted tubules.
Volume: 303
Issue: 4
Pages: F584-92
•
•
•
•
•
Publication
29232555 | J:252270
First Author: Guri Y
Year: 2017
Journal: Cancer Cell
Title: mTORC2 Promotes Tumorigenesis via Lipid Synthesis.
Volume: 32
Issue: 6
Pages: 807-823.e12
•
•
•
•
•
Publication
35579957 | J:327151
 
First Author: Wong C
Year: 2022
Journal: J Clin Invest
Title: mTORC2 mediates structural plasticity in distal nociceptive endings that contributes to pain hypersensitivity following inflammation.
Volume: 132
Issue: 15
•
•
•
•
•
Protein Coding Gene
MGP_CAROLIEiJ_G0019642 | -
Type: protein_coding_gene
Organism: Mus caroli
•
•
•
•
•
Protein Coding Gene
MGP_129S1SvImJ_G0021698 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AJ_G0021659 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AKRJ_G0021637 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_BALBcJ_G0021666 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C3HHeJ_G0021442 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI_C57BL6J_1926007 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C57BL6NJ_G0022105 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CASTEiJ_G0020958 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CBAJ_G0021411 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_DBA2J_G0021535 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_FVBNJ_G0021513 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_LPJ_G0021603 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NODShiLtJ_G0021538 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NZOHlLtJ_G0022128 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PWKPhJ_G0020701 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_WSBEiJ_G0021014 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PahariEiJ_G0016023 | -
Type: protein_coding_gene
Organism: Mus pahari
•
•
•
•
•
Protein Coding Gene
MGP_SPRETEiJ_G0020539 | -
Type: protein_coding_gene
Organism: Mus spretus
•
•
•
•
•
Publication
23077666 | J:192206
First Author: Bashir T
Year: 2012
Journal: PLoS One
Title: Conditional astroglial Rictor overexpression induces malignant glioma in mice.
Volume: 7
Issue: 10
Pages: e47741
•
•
•
•
•
Publication
19564418 | J:152614
First Author: Shu L
Year: 2009
Journal: Mol Cell Biol
Title: The mTORC2 complex regulates terminal differentiation of C2C12 myoblasts.
Volume: 29
Issue: 17
Pages: 4691-700
•
•
•
•
•
Publication
25970154 | J:315366
First Author: Li J
Year: 2015
Journal: Kidney Int
Title: Rictor/mTORC2 signaling mediates TGFβ1-induced fibroblast activation and kidney fibrosis.
Volume: 88
Issue: 3
Pages: 515-27
•
•
•
•
•
Publication
29949787 | J:318482
First Author: Qin B
Year: 2018
Journal: Cell Physiol Biochem
Title: MicroRNA-142-3p Induces Atherosclerosis-Associated Endothelial Cell Apoptosis by Directly Targeting Rictor.
Volume: 47
Issue: 4
Pages: 1589-1603
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5304388
Assay Type: Western blot
Annotation Date: 2012-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5304574
Age: postnatal
Image: 5
Specimen Label: Normal1
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5304388
Assay Type: Western blot
Annotation Date: 2012-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5304574
Age: postnatal
Image: 5
Specimen Label: Normal2
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5304388
Assay Type: Western blot
Annotation Date: 2012-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5304574
Age: postnatal
Image: 5
Specimen Label: Normal3
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5304388
Assay Type: Western blot
Annotation Date: 2012-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5304574
Age: postnatal
Image: 5
Specimen Label: Normal4
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6754092
Assay Type: Western blot
Annotation Date: 2021-08-30
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:6754099
Age: postnatal adult
Specimen Label: O
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6754092
Assay Type: Western blot
Annotation Date: 2021-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:6754099
Age: embryonic day 0.5
Specimen Label: 1C
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6754092
Assay Type: Western blot
Annotation Date: 2021-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:6754099
Age: embryonic day 1.0
Specimen Label: 2C
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6754092
Assay Type: Western blot
Annotation Date: 2021-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:6754099
Age: embryonic day 2.0
Specimen Label: 4C
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6754092
Assay Type: Western blot
Annotation Date: 2021-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:6754099
Age: embryonic day 2.5
Specimen Label: 8C
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6754092
Assay Type: Western blot
Annotation Date: 2021-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:6754099
Age: embryonic day 3.0
Specimen Label: MO
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6754092
Assay Type: Western blot
Annotation Date: 2021-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:6754099
Age: embryonic day 3.5
Specimen Label: BL
Detected: true
Specimen Num: 7
•
•
•
•
•
Publication
21266327 | J:170129
First Author: Gu Y
Year: 2011
Journal: Diabetes
Title: Rictor/mTORC2 is essential for maintaining a balance between beta-cell proliferation and cell size.
Volume: 60
Issue: 3
Pages: 827-37
•
•
•
•
•
Publication
30154246 | J:292349
First Author: Gui Y
Year: 2018
Journal: J Biol Chem
Title: Yap/Taz mediates mTORC2-stimulated fibroblast activation and kidney fibrosis.
Volume: 293
Issue: 42
Pages: 16364-16375
•
•
•
•
•
Publication
27593484 | J:333623
First Author: Yang T
Year: 2016
Journal: Cell Mol Immunol
Title: TSC1 controls IL-1β expression in macrophages via mTORC1-dependent C/EBPβ pathway.
Volume: 13
Issue: 5
Pages: 640-50
•
•
•
•
•
Publication
25175012 | J:274167
 
First Author: Zhu L
Year: 2014
Journal: Nat Commun
Title: TSC1 controls macrophage polarization to prevent inflammatory disease.
Volume: 5
Pages: 4696
•
•
•
•
•
Publication
21464307 | J:171369
First Author: Xie X
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: IkappaB kinase epsilon and TANK-binding kinase 1 activate AKT by direct phosphorylation.
Volume: 108
Issue: 16
Pages: 6474-9
•
•
•
•
•
Publication
29463562 | J:262092
First Author: Zhao Y
Year: 2018
Journal: Blood
Title: mTOR masters monocyte development in bone marrow by decreasing the inhibition of STAT5 on IRF8.
Volume: 131
Issue: 14
Pages: 1587-1599
•
•
•
•
•
Publication
21358638 | J:170683
First Author: Delgoffe GM
Year: 2011
Journal: Nat Immunol
Title: The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.
Volume: 12
Issue: 4
Pages: 295-303
•
•
•
•
•
Publication
34031386 | J:337333
First Author: Deng J
Year: 2021
Journal: Nat Commun
Title: The metabolic hormone leptin promotes the function of T(FH) cells and supports vaccine responses.
Volume: 12
Issue: 1
Pages: 3073
•
•
•
•
•
Publication
24282297 | J:205513
First Author: Wang Y
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Tuberous sclerosis 1 (Tsc1)-dependent metabolic checkpoint controls development of dendritic cells.
Volume: 110
Issue: 50
Pages: E4894-903
•
•
•
•
•
Publication
22958933 | J:191342
First Author: Magee JA
Year: 2012
Journal: Cell Stem Cell
Title: Temporal changes in PTEN and mTORC2 regulation of hematopoietic stem cell self-renewal and leukemia suppression.
Volume: 11
Issue: 3
Pages: 415-28
•
•
•
•
•
Allele
Rictor<Gt(CSD163)Byg> | MGI:3877685
 
Name: RPTOR independent companion of MTOR, complex 2; gene trap CSD163, BayGenomics
Allele Type: Gene trapped
•
•
•
•
•
Allele
Rictor<Gt(E122D06)Wrst> | MGI:3896218
 
Name: RPTOR independent companion of MTOR, complex 2; gene trap E122D06, German Gene Trap Consortium
Allele Type: Gene trapped
•
•
•
•
•
Allele
Rictor<Gt(AZ0553)Wtsi> | MGI:3857651
 
Name: RPTOR independent companion of MTOR, complex 2; gene trap AZ0553, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
•
•
•
•
•
Allele
Rictor<tm1.2Mgn> | MGI:3703322
Name: RPTOR independent companion of MTOR, complex 2; targeted mutation 1.2, Mark A Magnuson
Allele Type: Targeted
Attribute String: Null/knockout
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom