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Search results 201 to 300 out of 372 for Pikfyve

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:3714829
Assay Type: RNA in situ
Annotation Date: 2007-07-16
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3714854
Age: postnatal day 21
Image: 8b
Specimen Label: 8b
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3714829
Assay Type: RNA in situ
Annotation Date: 2007-07-16
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3714854
Age: postnatal day 56
Specimen Label: Not shown
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5310169
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3280922
Stage: TS22
Assay Id: MGI:5423493
Age: embryonic day 14.5
Specimen Label: EH1882; Specimen C2744
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5310169
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1833322
Stage: TS22
Assay Id: MGI:5423493
Age: embryonic day 14.5
Specimen Label: EH1882; Specimen C2744
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3714829
Assay Type: RNA in situ
Annotation Date: 2007-07-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287028
Stage: TS28
Assay Id: MGI:3714854
Age: postnatal day 21
Specimen Label: Table 1
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5310169
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287022
Stage: TS22
Assay Id: MGI:5423493
Age: embryonic day 14.5
Specimen Label: EH1882; Specimen C2744
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5310169
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423493
Age: embryonic day 14.5
Image: EH1882; Specimen C2744
Specimen Label: EH1882; Specimen C2744
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3714829
Assay Type: RNA in situ
Annotation Date: 2007-07-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3279028
Stage: TS28
Assay Id: MGI:3714854
Age: postnatal day 21
Image: 8b
Specimen Label: 8b
Detected: false
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3714829
Assay Type: RNA in situ
Annotation Date: 2007-07-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3279028
Stage: TS28
Assay Id: MGI:3714854
Age: postnatal day 56
Specimen Label: Not shown
Detected: false
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5310169
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1821522
Stage: TS22
Assay Id: MGI:5423493
Age: embryonic day 14.5
Specimen Label: EH1882; Specimen C2744
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5310169
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3557722
Stage: TS22
Assay Id: MGI:5423493
Age: embryonic day 14.5
Specimen Label: EH1882; Specimen C2744
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5310169
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1702122
Stage: TS22
Assay Id: MGI:5423493
Age: embryonic day 14.5
Specimen Label: EH1882; Specimen C2744
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507060
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5540017
Age: embryonic day 15.5
Image: GUDMAP:6502
Specimen Label: GUDMAP:6502
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3507060
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2874723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540017
Age: embryonic day 15.5
Image: GUDMAP:6502
Specimen Label: GUDMAP:6502
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5310169
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1756322
Stage: TS22
Assay Id: MGI:5423493
Age: embryonic day 14.5
Specimen Label: EH1882; Specimen C2744
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5310169
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1668822
Stage: TS22
Assay Id: MGI:5423493
Age: embryonic day 14.5
Specimen Label: EH1882; Specimen C2744
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5310169
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757722
Stage: TS22
Assay Id: MGI:5423493
Age: embryonic day 14.5
Specimen Label: EH1882; Specimen C2744
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3714829
Assay Type: RNA in situ
Annotation Date: 2007-07-16
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3525628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3714854
Age: postnatal day 21
Specimen Label: Table 1
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5310169
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757522
Stage: TS22
Assay Id: MGI:5423493
Age: embryonic day 14.5
Specimen Label: EH1882; Specimen C2744
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507060
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5540017
Age: embryonic day 15.5
Image: GUDMAP:6502
Specimen Label: GUDMAP:6502
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5310169
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738322
Stage: TS22
Assay Id: MGI:5423493
Age: embryonic day 14.5
Specimen Label: EH1882; Specimen C2744
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5310169
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1802422
Stage: TS22
Assay Id: MGI:5423493
Age: embryonic day 14.5
Specimen Label: EH1882; Specimen C2744
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3714829
Assay Type: RNA in situ
Annotation Date: 2007-07-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3521728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3714854
Age: postnatal day 21
Specimen Label: Table 1
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3714829
Assay Type: RNA in situ
Annotation Date: 2007-07-16
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3521728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3714854
Age: postnatal day 21
Image: 8b
Specimen Label: 8b
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3714829
Assay Type: RNA in situ
Annotation Date: 2007-07-16
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3521728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3714854
Age: postnatal day 56
Specimen Label: Not shown
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3714829
Assay Type: RNA in situ
Annotation Date: 2007-07-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3521728
Pattern: Patchy
Stage: TS28
Assay Id: MGI:3714854
Age: postnatal day 21
Image: 8d
Specimen Label: 8d
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3714829
Assay Type: RNA in situ
Annotation Date: 2007-07-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3521728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3714854
Age: postnatal day 21
Image: 8g
Specimen Label: 8g
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3507060
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540017
Age: embryonic day 15.5
Image: GUDMAP:6502
Specimen Label: GUDMAP:6502
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5310169
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1768022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423493
Age: embryonic day 14.5
Image: EH1882; Specimen C2744
Note: Expression was strong in the skull (base and vault).
Specimen Label: EH1882; Specimen C2744
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5310169
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2672022
Stage: TS22
Assay Id: MGI:5423493
Age: embryonic day 14.5
Note: Expression was not detected in whisker follicle.
Specimen Label: EH1882; Specimen C2744
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3714829
Assay Type: RNA in situ
Annotation Date: 2007-07-16
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3561128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3714854
Age: postnatal day 21
Specimen Label: Table 1
Detected: true
Specimen Num: 1
•
•
•
•
•
Publication
23680464 | J:201109
 
First Author: Yamazaki M
Year: 2013
Journal: Neurosci Lett
Title: Phosphatidylinositol 4-phosphate 5-kinase β regulates growth cone morphology and semaphorin 3A-triggered growth cone collapse in mouse dorsal root ganglion neurons.
Volume: 547
Pages: 59-64
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•
•
Publication
32188273 | J:325207
First Author: Qin Y
Year: 2020
Journal: Arterioscler Thromb Vasc Biol
Title: Phosphatidylinositol-(4,5)-Bisphosphate Regulates Plasma Cholesterol Through LDL (Low-Density Lipoprotein) Receptor Lysosomal Degradation.
Volume: 40
Issue: 5
Pages: 1311-1324
•
•
•
•
•
Publication
20841379 | J:182820
First Author: Halstead JR
Year: 2010
Journal: J Cell Sci
Title: Rac controls PIP5K localisation and PtdIns(4,5)Pâ‚‚ synthesis, which modulates vinculin localisation and neurite dynamics.
Volume: 123
Issue: Pt 20
Pages: 3535-46
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•
•
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Gene
307842 | Vac14
Type: gene
Organism: rat
•
•
•
•
•
Gene
489717 | VAC14
Type: gene
Organism: dog, domestic
•
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•
•
•
Gene
454220 | VAC14
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
533202 | VAC14
Type: gene
Organism: cattle
•
•
•
•
•
Gene
708741 | VAC14
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Publication
15018809 | J:75718
First Author: Akiba Y
Year: 2002
Journal: Brain Res Gene Expr Patterns
Title: Localization of mRNAs for phosphatidylinositol phosphate kinases in the mouse brain during development.
Volume: 1
Issue: 2
Pages: 123-33
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•
•
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Publication
25754822 | J:221126
First Author: Lee HK
Year: 2015
Journal: Neuron
Title: Daam2-PIP5K is a regulatory pathway for Wnt signaling and therapeutic target for remyelination in the CNS.
Volume: 85
Issue: 6
Pages: 1227-43
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•
•
•
Publication
37380769 | J:338195
First Author: Zhang X
Year: 2023
Journal: Nature
Title: Reprogramming tumour-associated macrophages to outcompete cancer cells.
Volume: 619
Issue: 7970
Pages: 616-623
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•
•
•
Publication
23322734 | J:193689
First Author: Takasuga S
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Critical roles of type III phosphatidylinositol phosphate kinase in murine embryonic visceral endoderm and adult intestine.
Volume: 110
Issue: 5
Pages: 1726-31
•
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•
•
•
Publication
23793062 | J:205441
First Author: Liang Y
Year: 2013
Journal: Nat Immunol
Title: The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells.
Volume: 14
Issue: 8
Pages: 858-66
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•
•
•
Publication
22988430 | J:190636
 
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
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•
•
•
•
Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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•
•
•
•
Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
•
•
•
•
•
Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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•
•
•
Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
•
•
•
•
•
Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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•
•
•
•
Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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•
•
•
Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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•
•
•
Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
•
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•
•
•
Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
•
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•
•
•
Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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•
•
•
Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
•
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•
•
•
Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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•
•
•
Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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•
•
•
Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
•
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•
•
•
Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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•
•
Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
•
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•
•
•
Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
•
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•
•
•
Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
•
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•
•
•
Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
•
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•
•
•
Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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•
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•
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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•
Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
•
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•
•
•
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
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•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
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•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
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•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
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•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
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•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
15542851 | J:95120
First Author: Sbrissa D
Year: 2004
Journal: Mol Cell Biol
Title: A mammalian ortholog of Saccharomyces cerevisiae Vac14 that associates with and up-regulates PIKfyve phosphoinositide 5-kinase activity.
Volume: 24
Issue: 23
Pages: 10437-47
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Publication
27335171 | J:236424
First Author: Compton LM
Year: 2016
Journal: Am J Physiol Cell Physiol
Title: Active vacuolar H+ ATPase and functional cycle of Rab5 are required for the vacuolation defect triggered by PtdIns(3,5)P2 loss under PIKfyve or Vps34 deficiency.
Volume: 311
Issue: 3
Pages: C366-77
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UniProt Feature
UniProt Feature
Begin: 156
Description: In ingls; loss of interaction with Pikfyve but not with Fig4.
Type: sequence variant
End: 156
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Interaction Experiment
Ikonomov OC (2009)
Description: Kinesin adapter JLP links PIKfyve to microtubule-based endosome-to-trans-Golgi network traffic of furin.
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Publication
20513353 | -
First Author: Hill EV
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Regulation of PIKfyve phosphorylation by insulin and osmotic stress.
Volume: 397
Issue: 4
Pages: 650-5
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Publication
17909029 | -
First Author: Kim J
Year: 2007
Journal: Cancer Res
Title: The phosphoinositide kinase PIKfyve mediates epidermal growth factor receptor trafficking to the nucleus.
Volume: 67
Issue: 19
Pages: 9229-37
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DO Term
DOID:0060448 | Fleck corneal dystrophy
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Protein
Q9Z1T6-3
Organism: Mus musculus/domesticus
Length: 497  
Fragment?: false
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Protein
Q9Z1T6-1
Organism: Mus musculus/domesticus
Length: 2052  
Fragment?: false
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Protein Domain
IPR037378 | PIKfyve_DEP
Type: Domain
Description: PIKfyve catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate []. It is part of the PI(3,5)P2 regulatory complex that regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) []. PIKfyve contains N-terminal Fyve finger and DEP domains, a central chaperonin-like domain and a C-terminal PIPK (phosphatidylinositol phosphate kinase) domain.
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GO Term
GO:0070772 | PAS complex
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Protein Coding Gene
MGI:2157980 | Vac14
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
23389034 | -
First Author: Alghamdi TA
Year: 2013
Journal: J Biol Chem
Title: Vac14 protein multimerization is a prerequisite step for Fab1 protein complex assembly and function.
Volume: 288
Issue: 13
Pages: 9363-72
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Protein Domain
IPR026825 | Vac14
Type: Family
Description: Vac14 is a component of the PI(3,5)P2 regulatory complex, which regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) []. This complex is composed of Atg18, Fig4, Fab1, Vac14 and Vac7 in yeast. In mammals it consists of PIKfyve, FIG4 and VAC14. Fab1/PIKfyve (Fab1 in yeast and PIKfyve in mammals) is a kinase that converts PI(3)P into PI(3,5)P2 by phosphorylation at the 5-position; conversely Fig4 dephosphorylates PI(3,5)P2 back to PI(3)P. Vac14 is a scaffolding adaptor protein whose multimerisation is a prerequisite step for PI(3,5)P2 complex assembly and function [].
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Publication
25578879 | J:219972
First Author: Vicinanza M
Year: 2015
Journal: Mol Cell
Title: PI(5)P regulates autophagosome biogenesis.
Volume: 57
Issue: 2
Pages: 219-34
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Publication
28552585 | J:260958
First Author: Morioka S
Year: 2017
Journal: Exp Cell Res
Title: Phosphoinositide phosphatase Sac3 regulates the cell surface expression of scavenger receptor A and formation of lipid droplets in macrophages.
Volume: 357
Issue: 2
Pages: 252-259
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Publication
24359958 | J:265024
 
First Author: Lenk GM
Year: 2014
Journal: Methods Enzymol
Title: Mouse models of PI(3,5)P2 deficiency with impaired lysosome function.
Volume: 534
Pages: 245-60
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