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Search results 101 to 200 out of 288 for Egln1

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1619321
Stage: TS21
Assay Id: MGI:3508310
Age: embryonic day 13.5
Image: 1
Note: The tissue was inner ear and ear structures.
Specimen Label: 1
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1619327
Stage: TS27
Assay Id: MGI:3508310
Age: postnatal newborn
Image: 2
Note: The tissue was inner ear and ear structures.
Specimen Label: 2
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2845723
Stage: TS23
Assay Id: MGI:5540196
Age: embryonic day 15.5
Image: GUDMAP:6247
Specimen Label: GUDMAP:6247
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1753621
Stage: TS21
Assay Id: MGI:3508310
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1753627
Stage: TS27
Assay Id: MGI:3508310
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1795023
Stage: TS23
Assay Id: MGI:5540196
Age: embryonic day 15.5
Image: GUDMAP:6247
Specimen Label: GUDMAP:6247
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1778727
Stage: TS27
Assay Id: MGI:3508310
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754421
Stage: TS21
Assay Id: MGI:3508310
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:3508310
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6285709
Assay Type: RNA in situ
Annotation Date: 2019-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6285712
Age: postnatal adult
Image: S4A bottom
Specimen Label: S4A bottom
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1666821
Stage: TS21
Assay Id: MGI:3508310
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1666827
Stage: TS27
Assay Id: MGI:3508310
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1647021
Stage: TS21
Assay Id: MGI:3508310
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1647027
Stage: TS27
Assay Id: MGI:3508310
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1647017
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:3509571
Age: embryonic day 10.5
Image: 1
Note: Authors stated that in some instances they could not determine expression levels with certainty.
Specimen Label: 1
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2854023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540196
Age: embryonic day 15.5
Image: GUDMAP:6247
Specimen Label: GUDMAP:6247
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3185821
Stage: TS21
Assay Id: MGI:3508310
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3185827
Stage: TS27
Assay Id: MGI:3508310
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6285709
Assay Type: RNA in situ
Annotation Date: 2019-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3525928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6285712
Age: postnatal adult
Image: S4A bottom
Specimen Label: S4A bottom
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2762123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540196
Age: embryonic day 15.5
Image: GUDMAP:6247
Specimen Label: GUDMAP:6247
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1832123
Stage: TS23
Assay Id: MGI:5540196
Age: embryonic day 15.5
Image: GUDMAP:6247
Specimen Label: GUDMAP:6247
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5540196
Age: embryonic day 15.5
Image: GUDMAP:6247
Specimen Label: GUDMAP:6247
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754021
Stage: TS21
Assay Id: MGI:3508310
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754027
Stage: TS27
Assay Id: MGI:3508310
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5540196
Age: embryonic day 15.5
Image: GUDMAP:6247
Specimen Label: GUDMAP:6247
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3280927
Stage: TS27
Assay Id: MGI:3508310
Age: postnatal newborn
Image: 2
Note: The tissue was olfactory epithelium and/or bulb.
Specimen Label: 2
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3267921
Stage: TS21
Assay Id: MGI:3508310
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3267927
Stage: TS27
Assay Id: MGI:3508310
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5540196
Age: embryonic day 15.5
Image: GUDMAP:6247
Specimen Label: GUDMAP:6247
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2874723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540196
Age: embryonic day 15.5
Image: GUDMAP:6247
Specimen Label: GUDMAP:6247
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757721
Stage: TS21
Assay Id: MGI:3508310
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:3508310
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6285709
Assay Type: RNA in situ
Annotation Date: 2019-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3525628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6285712
Age: postnatal adult
Image: S4A bottom
Specimen Label: S4A bottom
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5540196
Age: embryonic day 15.5
Image: GUDMAP:6247
Specimen Label: GUDMAP:6247
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6285709
Assay Type: RNA in situ
Annotation Date: 2019-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6285712
Age: embryonic day 14.5
Image: S4A top
Specimen Label: S4A top
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6285709
Assay Type: RNA in situ
Annotation Date: 2019-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6285712
Age: postnatal adult
Image: S4A bottom
Note: Expression is also in areas outside the cerebral cortex and hippocampus.
Specimen Label: S4A bottom
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540196
Age: embryonic day 15.5
Image: GUDMAP:6247
Specimen Label: GUDMAP:6247
Detected: true
Specimen Num: 1
•
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•
•
•
Publication
27827416 | J:254086
 
First Author: Futatsugi K
Year: 2016
Journal: Sci Rep
Title: Obesity-induced kidney injury is attenuated by amelioration of aberrant PHD2 activation in proximal tubules.
Volume: 6
Pages: 36533
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Publication
25647640 | J:330470
First Author: Hellfritsch J
Year: 2015
Journal: Antioxid Redox Signal
Title: Knockout of mitochondrial thioredoxin reductase stabilizes prolyl hydroxylase 2 and inhibits tumor growth and tumor-derived angiogenesis.
Volume: 22
Issue: 11
Pages: 938-50
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Publication
24990963 | J:212076
First Author: Zheng X
Year: 2014
Journal: Genes Dev
Title: Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase.
Volume: 28
Issue: 13
Pages: 1429-44
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Publication
32715763 | J:296776
First Author: Zhao Y
Year: 2020
Journal: Am J Physiol Renal Physiol
Title: Endothelial prolyl hydroxylase 2 is necessary for angiotensin II-mediated renal fibrosis and injury.
Volume: 319
Issue: 2
Pages: F345-F357
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Publication
26868537 | J:263576
 
First Author: Zeng H
Year: 2016
Journal: Sci Rep
Title: LPS causes pericyte loss and microvascular dysfunction via disruption of Sirt3/angiopoietins/Tie-2 and HIF-2α/Notch3 pathways.
Volume: 6
Pages: 20931
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Publication
30444491 | J:267502
   
First Author: Elamaa H
Year: 2018
Journal: Elife
Title: Angiopoietin-4-dependent venous maturation and fluid drainage in the peripheral retina.
Volume: 7
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Publication
28805660 | J:247852
First Author: Sadiku P
Year: 2017
Journal: J Clin Invest
Title: Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses.
Volume: 127
Issue: 9
Pages: 3407-3420
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Publication
21346252 | J:173281
First Author: Nytko KJ
Year: 2011
Journal: Blood
Title: Vitamin C is dispensable for oxygen sensing in vivo.
Volume: 117
Issue: 20
Pages: 5485-93
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Publication
31390373 | J:279103
First Author: Lindsey RC
Year: 2019
Journal: PLoS One
Title: Vitamin C effects on 5-hydroxymethylcytosine and gene expression in osteoblasts and chondrocytes: Potential involvement of PHD2.
Volume: 14
Issue: 8
Pages: e0220653
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Publication
23778187 | J:199066
First Author: Ikeda J
Year: 2013
Journal: J Am Heart Assoc
Title: Deletion of phd2 in myeloid lineage attenuates hypertensive cardiovascular remodeling.
Volume: 2
Issue: 3
Pages: e000178
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Publication
10543731 | J:60099
First Author: Moschella MC
Year: 1999
Journal: Gene Expr
Title: SM-20 is a novel growth factor-responsive gene regulated during skeletal muscle development and differentiation.
Volume: 8
Issue: 1
Pages: 59-66
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Publication
26863487 | J:233029
First Author: Stegen S
Year: 2016
Journal: Cell Metab
Title: HIF-1α Promotes Glutamine-Mediated Redox Homeostasis and Glycogen-Dependent Bioenergetics to Support Postimplantation Bone Cell Survival.
Volume: 23
Issue: 2
Pages: 265-79
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Publication
21983962 | J:268782
First Author: Takeda Y
Year: 2011
Journal: Nature
Title: Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis.
Volume: 479
Issue: 7371
Pages: 122-6
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Publication
26848160 | J:246928
First Author: Rahtu-Korpela L
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Hypoxia-Inducible Factor Prolyl 4-Hydroxylase-2 Inhibition Protects Against Development of Atherosclerosis.
Volume: 36
Issue: 4
Pages: 608-17
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Publication
29601782 | J:280645
First Author: Luo B
Year: 2018
Journal: FASEB J
Title: Hepatic PHD2/HIF-1α axis is involved in postexercise systemic energy homeostasis.
Volume: 32
Issue: 9
Pages: 4670-4680
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Publication
23913502 | J:231998
First Author: Mamlouk S
Year: 2014
Journal: Int J Cancer
Title: Loss of prolyl hydroxylase-2 in myeloid cells and T-lymphocytes impairs tumor development.
Volume: 134
Issue: 4
Pages: 849-58
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Publication
23798557 | J:204713
First Author: Kalucka J
Year: 2013
Journal: Mol Cell Biol
Title: Loss of epithelial hypoxia-inducible factor prolyl hydroxylase 2 accelerates skin wound healing in mice.
Volume: 33
Issue: 17
Pages: 3426-38
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Publication
37140003 | J:338024
First Author: Rosiewicz KS
Year: 2023
Journal: Glia
Title: HIF prolyl hydroxylase 2/3 deletion disrupts astrocytic integrity and exacerbates neuroinflammation.
Volume: 71
Issue: 8
Pages: 2024-2044
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Publication
30575721 | J:270317
First Author: Liu S
Year: 2018
Journal: Nat Commun
Title: Loss of Phd2 cooperates with BRAFV600E to drive melanomagenesis.
Volume: 9
Issue: 1
Pages: 5426
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Publication
30651640 | J:270606
First Author: Stegen S
Year: 2019
Journal: Nature
Title: HIF-1α metabolically controls collagen synthesis and modification in chondrocytes.
Volume: 565
Issue: 7740
Pages: 511-515
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Publication
24220244 | J:206742
First Author: Laoui D
Year: 2014
Journal: Cancer Res
Title: Tumor hypoxia does not drive differentiation of tumor-associated macrophages but rather fine-tunes the M2-like macrophage population.
Volume: 74
Issue: 1
Pages: 24-30
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Publication
29967369 | J:266095
First Author: Stegen S
Year: 2018
Journal: Nat Commun
Title: Osteocytic oxygen sensing controls bone mass through epigenetic regulation of sclerostin.
Volume: 9
Issue: 1
Pages: 2557
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Publication
27821476 | J:244936
 
First Author: Myllymäki MN
Year: 2017
Journal: Mol Cell Biol
Title: Notch Downregulation and Extramedullary Erythrocytosis in Hypoxia-Inducible Factor Prolyl 4-Hydroxylase 2-Deficient Mice.
Volume: 37
Issue: 2
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Publication
10795925 | J:62450
 
First Author: Murphy D
Year: 2000
Journal: Exp Physiol
Title: Transgenic studies in rats and mice on the osmotic regulation of vasopressin gene expression.
Volume: 85 Spec No
Pages: 211S-222S
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Publication
37847687 | J:342470
First Author: Barnes EA
Year: 2023
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Loss of prolyl hydroxylase 1 and 2 in SM22α-expressing cells prevents Hypoxia-Induced pulmonary hypertension.
Volume: 325
Issue: 6
Pages: L741-L755
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Publication
19720742 | J:153985
First Author: Minamishima YA
Year: 2009
Journal: Mol Cell Biol
Title: A feedback loop involving the Phd3 prolyl hydroxylase tunes the mammalian hypoxic response in vivo.
Volume: 29
Issue: 21
Pages: 5729-41
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Publication
26818499 | J:229447
First Author: Rajagopalan S
Year: 2016
Journal: J Neurosci
Title: Regulation of ATP13A2 via PHD2-HIF1α Signaling Is Critical for Cellular Iron Homeostasis: Implications for Parkinson's Disease.
Volume: 36
Issue: 4
Pages: 1086-95
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Publication
31029587 | J:274809
 
First Author: Leinonen H
Year: 2019
Journal: Neuropharmacology
Title: Null mutation in P4h-tm leads to decreased fear and anxiety and increased social behavior in mice.
Volume: 153
Pages: 63-72
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Publication
27082941 | J:332230
First Author: Rauner M
Year: 2016
Journal: J Bone Miner Res
Title: Increased EPO Levels Are Associated With Bone Loss in Mice Lacking PHD2 in EPO-Producing Cells.
Volume: 31
Issue: 10
Pages: 1877-1887
•
•
•
•
•
Publication
20733101 | J:179490
First Author: Moslehi J
Year: 2010
Journal: Circulation
Title: Loss of hypoxia-inducible factor prolyl hydroxylase activity in cardiomyocytes phenocopies ischemic cardiomyopathy.
Volume: 122
Issue: 10
Pages: 1004-16
•
•
•
•
•
Publication
23476056 | J:213317
First Author: Matsushima S
Year: 2013
Journal: Circ Res
Title: Broad suppression of NADPH oxidase activity exacerbates ischemia/reperfusion injury through inadvertent downregulation of hypoxia-inducible factor-1α and upregulation of peroxisome proliferator-activated receptor-α.
Volume: 112
Issue: 8
Pages: 1135-49
•
•
•
•
•
Publication
27981571 | J:241898
First Author: Van Welden S
Year: 2017
Journal: J Pathol
Title: Haematopoietic prolyl hydroxylase-1 deficiency promotes M2 macrophage polarization and is both necessary and sufficient to protect against experimental colitis.
Volume: 241
Issue: 4
Pages: 547-558
•
•
•
•
•
Publication
28716863 | J:247886
First Author: Tavernier SJ
Year: 2017
Journal: J Leukoc Biol
Title: Opposing regulation and roles for PHD3 in lung dendritic cells and alveolar macrophages.
Volume: 102
Issue: 4
Pages: 1115-1126
•
•
•
•
•
Publication
32814068 | J:301250
 
First Author: Smaila BD
Year: 2020
Journal: Exp Neurol
Title: Systemic hypoxia mimicry enhances axonal regeneration and functional recovery following peripheral nerve injury.
Volume: 334
Pages: 113436
•
•
•
•
•
Publication
24508125 | J:208042
First Author: Duan LJ
Year: 2014
Journal: Am J Pathol
Title: Hematological, hepatic, and retinal phenotypes in mice deficient for prolyl hydroxylase domain proteins in the liver.
Volume: 184
Issue: 4
Pages: 1240-50
•
•
•
•
•
Publication
33819286 | J:304962
First Author: Wei GZ
Year: 2021
Journal: PLoS One
Title: Hypoxia-inducible factor prolyl hydroxylase domain (PHD) inhibition after contusive spinal cord injury does not improve locomotor recovery.
Volume: 16
Issue: 4
Pages: e0249591
•
•
•
•
•
Publication
24440788 | J:206444
First Author: Takeda K
Year: 2014
Journal: Am J Pathol
Title: Improved vascular survival and growth in the mouse model of hindlimb ischemia by a remote signaling mechanism.
Volume: 184
Issue: 3
Pages: 686-96
•
•
•
•
•
Publication
24037093 | J:202021
First Author: Taniguchi CM
Year: 2013
Journal: Nat Med
Title: Cross-talk between hypoxia and insulin signaling through Phd3 regulates hepatic glucose and lipid metabolism and ameliorates diabetes.
Volume: 19
Issue: 10
Pages: 1325-30
•
•
•
•
•
Publication
33298456 | J:313923
 
First Author: Byts N
Year: 2021
Journal: eNeuro
Title: Transmembrane Prolyl 4-Hydroxylase is a Novel Regulator of Calcium Signaling in Astrocytes.
Volume: 8
Issue: 1
•
•
•
•
•
Publication
30248340 | J:270770
First Author: Strowitzki MJ
Year: 2018
Journal: Am J Pathol
Title: Loss of Prolyl-Hydroxylase 1 Protects against Biliary Fibrosis via Attenuated Activation of Hepatic Stellate Cells.
Volume: 188
Issue: 12
Pages: 2826-2838
•
•
•
•
•
Publication
28418093 | J:243598
First Author: Hulley PA
Year: 2017
Journal: J Pathol
Title: Hypoxia-inducible factor 1-alpha does not regulate osteoclastogenesis but enhances bone resorption activity via prolyl-4-hydroxylase 2.
Volume: 242
Issue: 3
Pages: 322-333
•
•
•
•
•
Publication
26774962 | J:232857
First Author: Quaegebeur A
Year: 2016
Journal: Cell Metab
Title: Deletion or Inhibition of the Oxygen Sensor PHD1 Protects against Ischemic Stroke via Reprogramming of Neuronal Metabolism.
Volume: 23
Issue: 2
Pages: 280-91
•
•
•
•
•
Publication
23690557 | J:212783
First Author: Bishop T
Year: 2013
Journal: J Physiol
Title: Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2.
Volume: 591
Issue: 14
Pages: 3565-77
•
•
•
•
•
Publication
20600011 | J:309903
First Author: Tambuwala MM
Year: 2010
Journal: Gastroenterology
Title: Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function.
Volume: 139
Issue: 6
Pages: 2093-101
•
•
•
•
•
Publication
27561929 | J:241612
 
First Author: Chowdhury R
Year: 2016
Journal: Nat Commun
Title: Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases.
Volume: 7
Pages: 12673
•
•
•
•
•
Publication
36509284 | J:332130
 
First Author: Kennel KB
Year: 2022
Journal: JCI Insight
Title: The HIF-prolyl hydroxylases have distinct and nonredundant roles in colitis-associated cancer.
Volume: 7
Issue: 22
•
•
•
•
•
Publication
22615432 | J:200057
First Author: Chen RL
Year: 2012
Journal: J Physiol
Title: Roles of individual prolyl-4-hydroxylase isoforms in the first 24 hours following transient focal cerebral ischaemia: insights from genetically modified mice.
Volume: 590
Issue: 16
Pages: 4079-91
•
•
•
•
•
Publication
18056838 | J:132720
First Author: Takeda K
Year: 2008
Journal: Blood
Title: Regulation of adult erythropoiesis by prolyl hydroxylase domain proteins.
Volume: 111
Issue: 6
Pages: 3229-35
•
•
•
•
•
Publication
17646578 | J:133568
First Author: Takeda K
Year: 2007
Journal: Circulation
Title: Essential role for prolyl hydroxylase domain protein 2 in oxygen homeostasis of the adult vascular system.
Volume: 116
Issue: 7
Pages: 774-81
•
•
•
•
•
Publication
27614241 | J:237383
First Author: Zhu K
Year: 2016
Journal: Gene
Title: Prolyl hydroxylase domain proteins regulate bone mass through their expression in osteoblasts.
Volume: 594
Issue: 1
Pages: 125-130
•
•
•
•
•
Publication
22786772 | J:189753
First Author: Kiss J
Year: 2012
Journal: J Immunol
Title: Loss of the oxygen sensor PHD3 enhances the innate immune response to abdominal sepsis.
Volume: 189
Issue: 4
Pages: 1955-65
•
•
•
•
•
Publication
36064857 | J:328341
First Author: Feng T
Year: 2022
Journal: Nat Commun
Title: Adipocyte-derived lactate is a signalling metabolite that potentiates adipose macrophage inflammation via targeting PHD2.
Volume: 13
Issue: 1
Pages: 5208
•
•
•
•
•
Publication
36625299 | J:339542
 
First Author: Duan LJ
Year: 2023
Journal: Biol Open
Title: Tailless and hypoxia inducible factor-2α cooperate to sustain proangiogenic states of retinal astrocytes in neonatal mice.
Volume: 12
Issue: 1
•
•
•
•
•
Publication
33464382 | J:306672
First Author: Watts D
Year: 2021
Journal: Cell Mol Life Sci
Title: HIF1α is a direct regulator of steroidogenesis in the adrenal gland.
Volume: 78
Issue: 7
Pages: 3577-3590
•
•
•
•
•
Publication
26075818 | J:225429
First Author: Xie L
Year: 2015
Journal: J Clin Invest
Title: PHD2/3-dependent hydroxylation tunes cardiac response to β-adrenergic stress via phospholamban.
Volume: 125
Issue: 7
Pages: 2759-71
•
•
•
•
•
Publication
22955912 | J:213191
First Author: Laitala A
Year: 2012
Journal: Blood
Title: Transmembrane prolyl 4-hydroxylase is a fourth prolyl 4-hydroxylase regulating EPO production and erythropoiesis.
Volume: 120
Issue: 16
Pages: 3336-44
•
•
•
•
•
Publication
26215701 | J:238613
First Author: Zhang CS
Year: 2015
Journal: Cell Res
Title: RHOBTB3 promotes proteasomal degradation of HIFα through facilitating hydroxylation and suppresses the Warburg effect.
Volume: 25
Issue: 9
Pages: 1025-42
•
•
•
•
•
Publication
32154744 | J:296815
First Author: Poblete JMS
Year: 2020
Journal: Am J Physiol Endocrinol Metab
Title: Macrophage HIF-1α mediates obesity-related adipose tissue dysfunction via interleukin-1 receptor-associated kinase M.
Volume: 318
Issue: 5
Pages: E689-E700
•
•
•
•
•
Publication
22262480 | J:183424
First Author: Kapitsinou PP
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Preischemic targeting of HIF prolyl hydroxylation inhibits fibrosis associated with acute kidney injury.
Volume: 302
Issue: 9
Pages: F1172-9
•
•
•
•
•
Publication
23667053 | J:200956
First Author: Singh RP
Year: 2013
Journal: Blood
Title: HIF prolyl hydroxylase 2 (PHD2) is a critical regulator of hematopoietic stem cell maintenance during steady-state and stress.
Volume: 121
Issue: 26
Pages: 5158-66
•
•
•
•
•
Publication
34718519 | J:323854
 
First Author: Hoang M
Year: 2022
Journal: Endocrinology
Title: Isoform-specific Roles of Prolyl Hydroxylases in the Regulation of Pancreatic β-Cell Function.
Volume: 163
Issue: 1
•
•
•
•
•
Publication
22611156 | J:189129
First Author: Querbes W
Year: 2012
Journal: Blood
Title: Treatment of erythropoietin deficiency in mice with systemically administered siRNA.
Volume: 120
Issue: 9
Pages: 1916-22
•
•
•
•
•
Publication
24789906 | J:212930
First Author: Kapitsinou PP
Year: 2014
Journal: J Clin Invest
Title: Endothelial HIF-2 mediates protection and recovery from ischemic kidney injury.
Volume: 124
Issue: 6
Pages: 2396-409
•
•
•
•
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