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Search results 1 to 100 out of 402 for Cth

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Hits by Pathway

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Hits by Category

Type Details Score
Gene
1491 | CTH
Type: gene
Organism: human
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Gene
539159 | CTH
Type: gene
Organism: cattle
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Gene
424716 | CTH
Type: gene
Organism: chicken
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Gene
322055 | cth
Type: gene
Organism: zebrafish
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Gene
696664 | CTH
Type: gene
Organism: macaque, rhesus
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Gene
394634 | cth
Type: gene
Organism: frog, western clawed
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Gene
24962 | Cth
Type: gene
Organism: rat
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Gene
479991 | CTH
Type: gene
Organism: dog, domestic
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Gene
456939 | CTH
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1339968 | Cth
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
31026586 | J:295527
 
First Author: Qin M
Year: 2019
Journal: Free Radic Biol Med
Title: Hydrogen sulfide protects against DSS-induced colitis by inhibiting NLRP3 inflammasome.
Volume: 137
Pages: 99-109
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Author
Nguyen CTH
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Publication
27273292 | J:269197
 
First Author: Markó L
Year: 2016
Journal: Sci Rep
Title: Role of Cystathionine Gamma-Lyase in Immediate Renal Impairment and Inflammatory Response in Acute Ischemic Kidney Injury.
Volume: 6
Pages: 27517
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Publication
37686458 | J:340533
 
First Author: Manandhar S
Year: 2023
Journal: Int J Mol Sci
Title: Pharmacological Inhibition and Genetic Deletion of Cystathionine Gamma-Lyase in Mice Protects against Organ Injury in Sepsis: A Key Role of Adhesion Molecules on Endothelial Cells.
Volume: 24
Issue: 17
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Publication
27865915 | J:251572
 
First Author: Gupta V
Year: 2017
Journal: J Mol Cell Cardiol
Title: Functional promoter polymorphisms direct the expression of cystathionine gamma-lyase gene in mouse models of essential hypertension.
Volume: 102
Pages: 61-73
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Publication
36860295 | J:335137
 
First Author: Katsouda A
Year: 2023
Journal: Front Pharmacol
Title: CTH/MPST double ablation results in enhanced vasorelaxation and reduced blood pressure via upregulation of the eNOS/sGC pathway.
Volume: 14
Pages: 1090654
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Publication
26232299 | J:232900
First Author: Madurga A
Year: 2015
Journal: Am J Physiol Lung Cell Mol Physiol
Title: The H2S-generating enzymes cystathionine β-synthase and cystathionine γ-lyase play a role in vascular development during normal lung alveolarization.
Volume: 309
Issue: 7
Pages: L710-24
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Publication
25499718 | J:219211
First Author: Hagiya Y
Year: 2015
Journal: Toxicol Appl Pharmacol
Title: Hemizygosity of transsulfuration genes confers increased vulnerability against acetaminophen-induced hepatotoxicity in mice.
Volume: 282
Issue: 2
Pages: 195-206
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Protein Coding Gene
MGP_CAROLIEiJ_G0025765 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0028013 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0027971 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0027937 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0027983 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0027713 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1339968 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0028426 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0027166 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0027688 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0027828 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0027795 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0027939 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0027828 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0028485 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0026889 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0027246 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0027215 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0026717 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
15038791 | J:91125
First Author: Ishii I
Year: 2004
Journal: Biochem J
Title: Murine cystathionine gamma-lyase: complete cDNA and genomic sequences, promoter activity, tissue distribution and developmental expression.
Volume: 381
Issue: Pt 1
Pages: 113-23
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Publication
18948540 | J:140705
First Author: Yang G
Year: 2008
Journal: Science
Title: H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase.
Volume: 322
Issue: 5901
Pages: 587-90
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Publication
33826201 | J:312261
First Author: Zhang Y
Year: 2021
Journal: FASEB J
Title: Cystathionine gamma-lyase/H2 S signaling facilitates myogenesis under aging and injury condition.
Volume: 35
Issue: 5
Pages: e21511
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Publication
24670645 | J:210468
First Author: Paul BD
Year: 2014
Journal: Nature
Title: Cystathionine γ-lyase deficiency mediates neurodegeneration in Huntington's disease.
Volume: 509
Issue: 7498
Pages: 96-100
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Publication
26271715 | J:310894
 
First Author: Syhr KMJ
Year: 2015
Journal: Brain Res
Title: The H2S-producing enzyme CSE is dispensable for the processing of inflammatory and neuropathic pain.
Volume: 1624
Pages: 380-389
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Publication
31611932 | J:288025
First Author: Jiao Y
Year: 2019
Journal: Exp Ther Med
Title: Mechanism of H2S-mediated ROCK inhibition of total flavones of Rhododendra against myocardial ischemia injury.
Volume: 18
Issue: 5
Pages: 3783-3792
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Publication
23449534 | J:288346
First Author: Bos EM
Year: 2013
Journal: J Am Soc Nephrol
Title: Cystathionine γ-lyase protects against renal ischemia/reperfusion by modulating oxidative stress.
Volume: 24
Issue: 5
Pages: 759-70
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Publication
28851593 | J:278162
 
First Author: Wang J
Year: 2017
Journal: Respir Physiol Neurobiol
Title: Role of cystathionine-γ-lyase in hypoxia-induced changes in TASK activity, intracellular [Ca2+] and ventilation in mice.
Volume: 246
Pages: 98-106
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Publication
26276101 | J:226176
First Author: Jiang H
Year: 2015
Journal: Biol Open
Title: Sex-specific dysregulation of cysteine oxidation and the methionine and folate cycles in female cystathionine gamma-lyase null mice: a serendipitous model of the methylfolate trap.
Volume: 4
Issue: 9
Pages: 1154-62
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Publication
23183179 | J:194206
First Author: Zhang L
Year: 2013
Journal: Endocrinology
Title: Hydrogen sulfide impairs glucose utilization and increases gluconeogenesis in hepatocytes.
Volume: 154
Issue: 1
Pages: 114-26
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Publication
27986657 | J:240034
First Author: Li H
Year: 2017
Journal: Am J Physiol Heart Circ Physiol
Title: The interaction of estrogen and CSE/H2S pathway in the development of atherosclerosis.
Volume: 312
Issue: 3
Pages: H406-H414
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Publication
24778456 | J:216526
First Author: Zhao K
Year: 2014
Journal: EMBO Rep
Title: S-sulfhydration of MEK1 leads to PARP-1 activation and DNA damage repair.
Volume: 15
Issue: 7
Pages: 792-800
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Publication
30002061 | J:285144
First Author: Yuan S
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Cystathionine γ-Lyase Modulates Flow-Dependent Vascular Remodeling.
Volume: 38
Issue: 9
Pages: 2126-2136
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Publication
35933902 | J:327229
 
First Author: Thanki KK
Year: 2022
Journal: Redox Biol
Title: Deletion of cystathionine-γ-lyase in bone marrow-derived cells promotes colitis-associated carcinogenesis.
Volume: 55
Pages: 102417
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Publication
32186933 | J:293460
First Author: Xue WL
Year: 2020
Journal: Am J Physiol Cell Physiol
Title: Hydrogen sulfide rescues high glucose-induced migration dysfunction in HUVECs by upregulating miR-126-3p.
Volume: 318
Issue: 5
Pages: C857-C869
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Publication
30472982 | J:288187
   
First Author: Leigh J
Year: 2018
Journal: Can Urol Assoc J
Title: Endogenous H2S production deficiencies lead to impaired renal erythropoietin production.
Pages: E210-E219
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Publication
21310231 | J:171963
First Author: Mani S
Year: 2011
Journal: Free Radic Biol Med
Title: A critical life-supporting role for cystathionine γ-lyase in the absence of dietary cysteine supply.
Volume: 50
Issue: 10
Pages: 1280-7
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Publication
23395089 | J:195776
First Author: Zhang G
Year: 2013
Journal: Am J Pathol
Title: The inhibitory role of hydrogen sulfide in airway hyperresponsiveness and inflammation in a mouse model of asthma.
Volume: 182
Issue: 4
Pages: 1188-95
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Publication
23758073 | J:320030
First Author: Shirozu K
Year: 2014
Journal: Antioxid Redox Signal
Title: Cystathionine γ-lyase deficiency protects mice from galactosamine/lipopolysaccharide-induced acute liver failure.
Volume: 20
Issue: 2
Pages: 204-16
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Publication
26194202 | J:258765
First Author: Kolluru GK
Year: 2015
Journal: Cardiovasc Res
Title: Cystathionine γ-lyase regulates arteriogenesis through NO-dependent monocyte recruitment.
Volume: 107
Issue: 4
Pages: 590-600
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Publication
27436896 | J:235138
First Author: Sbodio JI
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Transcriptional control of amino acid homeostasis is disrupted in Huntington's disease.
Volume: 113
Issue: 31
Pages: 8843-8
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Publication
27531649 | J:260278
First Author: Yuan G
Year: 2016
Journal: Sci Signal
Title: H2S production by reactive oxygen species in the carotid body triggers hypertension in a rodent model of sleep apnea.
Volume: 9
Issue: 441
Pages: ra80
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Publication
31123718 | J:289666
 
First Author: Yang J
Year: 2019
Journal: Commun Biol
Title: Non-enzymatic hydrogen sulfide production from cysteine in blood is catalyzed by iron and vitamin B6.
Volume: 2
Pages: 194
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Publication
20556885 | J:161361
First Author: Peng YJ
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: H2S mediates O2 sensing in the carotid body.
Volume: 107
Issue: 23
Pages: 10719-24
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Publication
31421132 | J:293494
 
First Author: Módis K
Year: 2019
Journal: Biochem Pharmacol
Title: Cystathionine-γ-lyase (CSE) deficiency increases erythropoiesis and promotes mitochondrial electron transport via the upregulation of coproporphyrinogen III oxidase and consequent stimulation of heme biosynthesis.
Volume: 169
Pages: 113604
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Publication
20051385 | J:176108
First Author: Yang G
Year: 2010
Journal: Cardiovasc Res
Title: Cystathionine gamma-lyase deficiency and overproliferation of smooth muscle cells.
Volume: 86
Issue: 3
Pages: 487-95
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Publication
26272431 | J:231409
First Author: Ju Y
Year: 2015
Journal: Biochim Biophys Acta
Title: H2S-induced S-sulfhydration of pyruvate carboxylase contributes to gluconeogenesis in liver cells.
Volume: 1850
Issue: 11
Pages: 2293-303
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Publication
25205851 | J:259015
First Author: Altaany Z
Year: 2014
Journal: Sci Signal
Title: The coordination of S-sulfhydration, S-nitrosylation, and phosphorylation of endothelial nitric oxide synthase by hydrogen sulfide.
Volume: 7
Issue: 342
Pages: ra87
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Publication
21718679 | J:174385
First Author: Yang G
Year: 2011
Journal: Am J Pathol
Title: The pathogenic role of cystathionine γ-lyase/hydrogen sulfide in streptozotocin-induced diabetes in mice.
Volume: 179
Issue: 2
Pages: 869-79
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Publication
21808008 | J:175609
First Author: Suzuki K
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Hydrogen sulfide replacement therapy protects the vascular endothelium in hyperglycemia by preserving mitochondrial function.
Volume: 108
Issue: 33
Pages: 13829-34
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Publication
29191638 | J:257704
First Author: Yang G
Year: 2018
Journal: Biochim Biophys Acta
Title: Cystathionine gamma-lyase/hydrogen sulfide system is essential for adipogenesis and fat mass accumulation in mice.
Volume: 1863
Issue: 2
Pages: 165-176
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Publication
21980127 | J:196558
First Author: Mustafa AK
Year: 2011
Journal: Circ Res
Title: Hydrogen sulfide as endothelium-derived hyperpolarizing factor sulfhydrates potassium channels.
Volume: 109
Issue: 11
Pages: 1259-68
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Publication
23122812 | J:191091
First Author: Fu M
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Is cystathionine gamma-lyase protein expressed in the heart?
Volume: 428
Issue: 4
Pages: 469-74
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Publication
25695633 | J:226206
First Author: Jiang Z
Year: 2015
Journal: PLoS One
Title: Role of hydrogen sulfide in early blood-brain barrier disruption following transient focal cerebral ischemia.
Volume: 10
Issue: 2
Pages: e0117982
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Publication
23904600 | J:327894
First Author: Sha L
Year: 2013
Journal: J Neurosci
Title: Hydrogen sulfide selectively potentiates central preganglionic fast nicotinic synaptic input in mouse superior mesenteric ganglion.
Volume: 33
Issue: 31
Pages: 12638-46
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Publication
19955410 | J:155522
First Author: Papapetropoulos A
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Hydrogen sulfide is an endogenous stimulator of angiogenesis.
Volume: 106
Issue: 51
Pages: 21972-7
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Publication
31319489 | J:290730
 
First Author: Akahoshi N
Year: 2019
Journal: Int J Mol Sci
Title: Preeclampsia-Like Features and Partial Lactation Failure in Mice Lacking Cystathionine γ-Lyase-An Animal Model of Cystathioninuria.
Volume: 20
Issue: 14
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Publication
24008358 | J:210565
First Author: Ang AD
Year: 2013
Journal: Am J Physiol Gastrointest Liver Physiol
Title: The effect of CSE gene deletion in caerulein-induced acute pancreatitis in the mouse.
Volume: 305
Issue: 10
Pages: G712-21
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Publication
24246677 | J:211490
First Author: Okamoto M
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Endogenous hydrogen sulfide protects pancreatic beta-cells from a high-fat diet-induced glucotoxicity and prevents the development of type 2 diabetes.
Volume: 442
Issue: 3-4
Pages: 227-33
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Publication
36285798 | J:331543
First Author: Suzuki J
Year: 2022
Journal: J Am Heart Assoc
Title: Hydrogen Sulfide Attenuates Lymphedema Via the Induction of Lymphangiogenesis Through a PI3K/Akt-Dependent Mechanism.
Volume: 11
Issue: 21
Pages: e026889
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Publication
27518439 | J:251283
First Author: Gaddam RR
Year: 2016
Journal: PLoS One
Title: Cystathionine-Gamma-Lyase Gene Deletion Protects Mice against Inflammation and Liver Sieve Injury following Polymicrobial Sepsis.
Volume: 11
Issue: 8
Pages: e0160521
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Publication
34061822 | J:312328
First Author: Sueiro-Olivares M
Year: 2021
Journal: PLoS Biol
Title: Fungal and host protein persulfidation are functionally correlated and modulate both virulence and antifungal response.
Volume: 19
Issue: 6
Pages: e3001247
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Publication
33628390 | J:315736
 
First Author: Wang G
Year: 2021
Journal: Oxid Med Cell Longev
Title: Hydrogen Sulfide Is a Regulator of Hemoglobin Oxygen-Carrying Capacity via Controlling 2,3-BPG Production in Erythrocytes.
Volume: 2021
Pages: 8877691
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Publication
22744006 | J:192679
First Author: Makarenko VV
Year: 2012
Journal: Am J Physiol Cell Physiol
Title: Endogenous H2S is required for hypoxic sensing by carotid body glomus cells.
Volume: 303
Issue: 9
Pages: C916-23
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Publication
24357058 | J:222824
First Author: Itou T
Year: 2014
Journal: Arterioscler Thromb Vasc Biol
Title: Cystathionine γ-lyase accelerates osteoclast differentiation: identification of a novel regulator of osteoclastogenesis by proteomic analysis.
Volume: 34
Issue: 3
Pages: 626-34
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Publication
29730290 | J:270488
First Author: Mo S
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Cystathionine gamma lyase-H2S contributes to osteoclastogenesis during bone remodeling induced by mechanical loading.
Volume: 501
Issue: 2
Pages: 471-477
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Publication
27848249 | J:288350
First Author: Ci L
Year: 2017
Journal: Antioxid Redox Signal
Title: Cystathionine γ-Lyase Deficiency Exacerbates CCl4-Induced Acute Hepatitis and Fibrosis in the Mouse Liver.
Volume: 27
Issue: 3
Pages: 133-149
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Publication
30986815 | J:295797
First Author: Ivanciuc T
Year: 2019
Journal: Pediatr Res
Title: Cystathionine γ-lyase deficiency enhances airway reactivity and viral-induced disease in mice exposed to side-stream tobacco smoke.
Volume: 86
Issue: 1
Pages: 39-46
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Publication
29844591 | J:313220
First Author: Wu W
Year: 2019
Journal: Cell Mol Immunol
Title: Cystathionine-γ-lyase ameliorates the histone demethylase JMJD3-mediated autoimmune response in rheumatoid arthritis.
Volume: 16
Issue: 8
Pages: 694-705
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GXD Expression
GXD Expression
     
Probe: MGI:3794608
Assay Type: Northern blot
Annotation Date: 2008-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3794609
Age: postnatal week 8
Specimen Label: Brain
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3794608
Assay Type: Northern blot
Annotation Date: 2008-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3794609
Age: postnatal week 8
Specimen Label: Heart
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3794608
Assay Type: Northern blot
Annotation Date: 2008-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3794609
Age: postnatal week 8
Specimen Label: Lung
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
       
Probe: MGI:3794608
Assay Type: Northern blot
Annotation Date: 2008-06-21
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:3794609
Age: postnatal week 8
Specimen Label: Thymus
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3794608
Assay Type: Northern blot
Annotation Date: 2008-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3794609
Age: postnatal week 8
Specimen Label: Liver
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:3794608
Assay Type: Northern blot
Annotation Date: 2008-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3794609
Age: postnatal week 8
Specimen Label: Kidney
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
       
Probe: MGI:3794608
Assay Type: Northern blot
Annotation Date: 2008-06-21
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3794609
Age: postnatal week 8
Specimen Label: Spleen
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:3794608
Assay Type: Northern blot
Annotation Date: 2008-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:3794609
Age: postnatal week 8
Specimen Label: Stomach
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:3794608
Assay Type: Northern blot
Annotation Date: 2008-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283428
Stage: TS28
Assay Id: MGI:3794609
Age: postnatal week 8
Specimen Label: S intestine
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
       
Probe: MGI:3794608
Assay Type: Northern blot
Annotation Date: 2008-06-21
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:3794609
Age: postnatal week 8
Specimen Label: S muscle
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
       
Probe: MGI:3794608
Assay Type: Northern blot
Annotation Date: 2008-06-21
Strength: Not Specified
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3794609
Age: postnatal week 8
Specimen Label: Testis
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3794608
Assay Type: Northern blot
Annotation Date: 2008-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3511228
Stage: TS28
Assay Id: MGI:3794609
Age: postnatal week 8
Specimen Label: Adipose
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
       
Probe: MGI:3794613
Assay Type: Western blot
Annotation Date: 2008-06-21
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3794616
Age: postnatal
Specimen Label: Brain
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
       
Probe: MGI:3794613
Assay Type: Western blot
Annotation Date: 2008-06-21
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3794616
Age: postnatal
Specimen Label: Heart
Specimen Num: 2
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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