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Search results 1 to 100 out of 133 for Taf4

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Type Details Score
Gene
6874 | TAF4
Type: gene
Organism: human
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Gene
682097 | Taf4
Type: gene
Organism: rat
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Gene
477280 | TAF4
Type: gene
Organism: dog, domestic
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Gene
789854 | TAF4
Type: gene
Organism: cattle
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Gene
419223 | TAF4
Type: gene
Organism: chicken
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Gene
720204 | TAF4
Type: gene
Organism: macaque, rhesus
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Gene
779738 | taf4
Type: gene
Organism: frog, western clawed
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Gene
458381 | TAF4
Type: gene
Organism: chimpanzee
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Protein Domain
IPR045144 | TAF4
Type: Family
Description: Accurate transcription initiation at protein-coding genes by RNA polymerase II requires the assembly of a multiprotein complex around the mRNA start site. Transcription factor TFIID is one of the general factors involved in this process. Yeast TFIID comprises the TATA binding protein and 14 TBP-associated factors (TAFIIs), nine of which contain histone-fold domains. The C-terminal region of the TFIID-specific yeast TAF4 (yTAF4) containing the HFD shares strong sequence similarity with Drosophila (d)TAF4 and human TAF4. A structure/function analysis of yTAF4 demonstrates that the HFD, a short conserved C-terminal domain (CCTD), and the region separating them are all required for yTAF4 function [, ].
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Protein Coding Gene
MGI:2152346 | Taf4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q8C0S6
Organism: Mus musculus/domesticus
Length: 153  
Fragment?: true
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Publication
12237303 | -
First Author: Thuault S
Year: 2002
Journal: J Biol Chem
Title: Functional analysis of the TFIID-specific yeast TAF4 (yTAF(II)48) reveals an unexpected organization of its histone-fold domain.
Volume: 277
Issue: 47
Pages: 45510-7
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Publication
30442764 | -
 
First Author: Patel AB
Year: 2018
Journal: Science
Title: Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Volume: 362
Issue: 6421
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Publication
23873942 | J:199361
First Author: Chen WY
Year: 2013
Journal: Genes Dev
Title: A TAF4 coactivator function for E proteins that involves enhanced TFIID binding.
Volume: 27
Issue: 14
Pages: 1596-609
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Publication
16015375 | J:125257
First Author: Mengus G
Year: 2005
Journal: EMBO J
Title: TAF4 inactivation in embryonic fibroblasts activates TGF beta signalling and autocrine growth.
Volume: 24
Issue: 15
Pages: 2753-67
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Publication
24498316 | J:212849
First Author: Martianov I
Year: 2014
Journal: PLoS One
Title: TAF4 inactivation reveals the 3 dimensional growth promoting activities of collagen 6A3.
Volume: 9
Issue: 2
Pages: e87365
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Publication
17626060 | J:124111
First Author: Fadloun A
Year: 2007
Journal: Development
Title: The TFIID subunit TAF4 regulates keratinocyte proliferation and has cell-autonomous and non-cell-autonomous tumour suppressor activity in mouse epidermis.
Volume: 134
Issue: 16
Pages: 2947-58
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Protein
A0A3B2W725
Organism: Mus musculus/domesticus
Length: 855  
Fragment?: false
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Protein
A0A3Q4EGS4
Organism: Mus musculus/domesticus
Length: 850  
Fragment?: false
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Protein
Q91WW6
Organism: Mus musculus/domesticus
Length: 662  
Fragment?: true
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Protein
A0A2I3BPN6
Organism: Mus musculus/domesticus
Length: 1030  
Fragment?: false
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Protein
G5E8Z2
Organism: Mus musculus/domesticus
Length: 850  
Fragment?: false
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Protein
E9QAP7
Organism: Mus musculus/domesticus
Length: 1042  
Fragment?: false
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Publication
27026076 | J:236825
 
First Author: Langer D
Year: 2016
Journal: Nat Commun
Title: Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation.
Volume: 7
Pages: 11063
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Publication
36639541 | J:333939
First Author: Säisä-Borreill S
Year: 2023
Journal: Cell Death Differ
Title: General transcription factor TAF4 antagonizes epigenetic silencing by Polycomb to maintain intestine stem cell functions.
Volume: 30
Issue: 3
Pages: 839-853
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Publication
29316427 | J:253748
First Author: Xu Y
Year: 2018
Journal: Cancer Cell
Title: A TFIID-SAGA Perturbation that Targets MYB and Suppresses Acute Myeloid Leukemia.
Volume: 33
Issue: 1
Pages: 13-28.e8
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Publication
34385420 | J:313401
First Author: Kleiber T
Year: 2021
Journal: Cell Death Dis
Title: Single cell transcriptomics reveal trans-differentiation of pancreatic beta cells following inactivation of the TFIID subunit Taf4.
Volume: 12
Issue: 8
Pages: 790
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Publication
25209997 | J:228779
 
First Author: Alpern D
Year: 2014
Journal: Elife
Title: TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation.
Volume: 3
Pages: e03613
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Publication
12665565 | J:83344
First Author: Pointud JC
Year: 2003
Journal: J Cell Sci
Title: The intracellular localisation of TAF7L, a paralogue of transcription factor TFIID subunit TAF7, is developmentally regulated during male germ-cell differentiation.
Volume: 116
Issue: Pt 9
Pages: 1847-58
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Protein Coding Gene
MGP_CAROLIEiJ_G0024769 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0026981 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0026947 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0026917 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0026956 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0026697 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2152346 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0027402 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0026156 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0026674 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0026812 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0026778 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0026913 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0026797 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0027461 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0025892 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0026228 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0026213 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0025692 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
11570813 | J:71956
First Author: Metsis M
Year: 2001
Journal: Exp Cell Res
Title: Cell-type-specific expression of the TFIID component TAF(II)135 in the nervous system.
Volume: 269
Issue: 2
Pages: 214-21
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GXD Expression
GXD Expression
   
Probe: MGI:6406319
Assay Type: RT-PCR
Annotation Date: 2020-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674815
Stage: TS15
Assay Id: MGI:6406693
Age: embryonic day 9.25
Image: S9
Specimen Label: Control
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6406319
Assay Type: RT-PCR
Annotation Date: 2020-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674815
Stage: TS15
Assay Id: MGI:6406693
Age: embryonic day 9.25
Image: S9
Specimen Label: TCre/+;Taf10
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3843922
Assay Type: Northern blot
Annotation Date: 2009-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:3843923
Age: embryonic day 13.0
Specimen Label: E13
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3843922
Assay Type: Northern blot
Annotation Date: 2009-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:3843923
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3843922
Assay Type: Northern blot
Annotation Date: 2009-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:3843923
Age: embryonic day 17.0
Specimen Label: E17
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3843922
Assay Type: Northern blot
Annotation Date: 2009-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3843923
Age: postnatal day 4
Specimen Label: P4
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3843922
Assay Type: Northern blot
Annotation Date: 2009-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3843923
Age: postnatal adult
Specimen Label: Ad
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:3843922
Assay Type: RNA in situ
Annotation Date: 2009-05-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754927
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3843924
Age: postnatal day 1
Specimen Label: 2 P1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3843922
Assay Type: RNA in situ
Annotation Date: 2009-05-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3286927
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3843924
Age: postnatal day 1
Specimen Label: 2 P1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3843922
Assay Type: RNA in situ
Annotation Date: 2009-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3843924
Age: postnatal adult
Specimen Label: 2 Ad
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:3843922
Assay Type: RNA in situ
Annotation Date: 2009-05-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3843924
Age: postnatal day 1
Specimen Label: 2 P1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3843922
Assay Type: RNA in situ
Annotation Date: 2009-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3843924
Age: postnatal adult
Specimen Label: 2 Ad
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3843922
Assay Type: RNA in situ
Annotation Date: 2009-05-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3523528
Stage: TS28
Assay Id: MGI:3843924
Age: postnatal adult
Specimen Label: 3 C,D
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:3843922
Assay Type: RNA in situ
Annotation Date: 2009-05-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3525328
Stage: TS28
Assay Id: MGI:3843924
Age: postnatal adult
Specimen Label: 3 A,B
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:3843922
Assay Type: RNA in situ
Annotation Date: 2009-05-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3284527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3843924
Age: postnatal day 1
Specimen Label: 2 P1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3843922
Assay Type: RNA in situ
Annotation Date: 2009-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3843924
Age: postnatal adult
Specimen Label: 2 Ad
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:3843922
Assay Type: RNA in situ
Annotation Date: 2009-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3843924
Age: postnatal adult
Note: Expression is in large scattered neurons of the hilar region of the hippocampus.
Specimen Label: 4 B,C
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:3843926
Assay Type: Immunohistochemistry
Annotation Date: 2009-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3843927
Age: postnatal adult
Note: Expression is in large scattered neurons of the hilar region of the hippocampus.
Specimen Label: 4A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3843922
Assay Type: RNA in situ
Annotation Date: 2009-05-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3522328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3843924
Age: postnatal adult
Specimen Label: 3 C,D
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:3843926
Assay Type: Immunohistochemistry
Annotation Date: 2009-05-12
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3522328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3843927
Age: postnatal adult
Note: Expression was nearly undetectable.
Specimen Label: Not shown
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3843922
Assay Type: RNA in situ
Annotation Date: 2009-05-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1876827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3843924
Age: postnatal day 1
Specimen Label: 2 P1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3843922
Assay Type: RNA in situ
Annotation Date: 2009-05-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3591527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3843924
Age: postnatal day 1
Specimen Label: 2 P1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3843922
Assay Type: RNA in situ
Annotation Date: 2009-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Patchy
Stage: TS28
Assay Id: MGI:3843924
Age: postnatal adult
Note: Expression is in neurons.
Specimen Label: 3 A,B
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:3843922
Assay Type: RNA in situ
Annotation Date: 2009-05-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757721
Pattern: Uniform
Stage: TS21
Assay Id: MGI:3843924
Age: embryonic day 13.0
Specimen Label: 2 E13
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3843922
Assay Type: RNA in situ
Annotation Date: 2009-05-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Uniform
Stage: TS21
Assay Id: MGI:3843924
Age: embryonic day 13.0
Specimen Label: 2 E13
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3843922
Assay Type: RNA in situ
Annotation Date: 2009-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3843924
Age: postnatal adult
Note: Expression is in most regions.
Specimen Label: 2 Ad
Detected: true
Specimen Num: 3
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Publication
11557891 | J:71679
First Author: Freiman RN
Year: 2001
Journal: Science
Title: Requirement of tissue-selective TBP-associated factor TAFII105 in ovarian development.
Volume: 293
Issue: 5537
Pages: 2084-7
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Publication
14580349 | J:86236
First Author: Guermah M
Year: 2003
Journal: Mol Cell
Title: The TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis.
Volume: 12
Issue: 4
Pages: 991-1001
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Publication
31932482 | J:292511
 
First Author: Gustafson EA
Year: 2020
Journal: Mol Cell Biol
Title: ZFP628 Is a TAF4b-Interacting Transcription Factor Required for Mouse Spermiogenesis.
Volume: 40
Issue: 7
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Publication
18722179 | J:138818
First Author: Tatarakis A
Year: 2008
Journal: Mol Cell
Title: Dominant and redundant functions of TFIID involved in the regulation of hepatic genes.
Volume: 31
Issue: 4
Pages: 531-43
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Publication
35361962 | J:337771
First Author: El-Saafin F
Year: 2022
Journal: Cell Death Differ
Title: Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death.
Volume: 29
Issue: 5
Pages: 1013-1027
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Publication
28893950 | J:245730
First Author: Bardot P
Year: 2017
Journal: Development
Title: The TAF10-containing TFIID and SAGA transcriptional complexes are dispensable for early somitogenesis in the mouse embryo.
Volume: 144
Issue: 20
Pages: 3808-3818
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Publication
22323595 | J:181994
First Author: Kamileri I
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria.
Volume: 109
Issue: 8
Pages: 2995-3000
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Publication
15741177 | J:126097
First Author: Cobellis G
Year: 2005
Journal: Nucleic Acids Res
Title: Tagging genes with cassette-exchange sites.
Volume: 33
Issue: 4
Pages: e44
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
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First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
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First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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