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Search results 101 to 200 out of 1576 for Nfe2l2

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Type Details Score
Publication
First Author: Joshi N
Year: 2017
Journal: PLoS One
Title: Nrf2 is highly expressed in neutrophils, but myeloid cell-derived Nrf2 is dispensable for wound healing in mice.
Volume: 12
Issue: 10
Pages: e0187162
Publication
First Author: Piantadosi CA
Year: 2011
Journal: J Biol Chem
Title: Heme oxygenase-1 couples activation of mitochondrial biogenesis to anti-inflammatory cytokine expression.
Volume: 286
Issue: 18
Pages: 16374-85
Publication
First Author: Xu Z
Year: 2014
Journal: Diabetologia
Title: NRF2 plays a protective role in diabetic retinopathy in mice.
Volume: 57
Issue: 1
Pages: 204-13
Publication
First Author: LaPash Daniels CM
Year: 2012
Journal: J Neurosci
Title: Beneficial effects of Nrf2 overexpression in a mouse model of Alexander disease.
Volume: 32
Issue: 31
Pages: 10507-15
Publication  
First Author: Tan RJ
Year: 2016
Journal: Sci Rep
Title: Keap1 hypomorphism protects against ischemic and obstructive kidney disease.
Volume: 6
Pages: 36185
Publication  
First Author: Blasiak J
Year: 2021
Journal: Int J Mol Sci
Title: Epithelial-Mesenchymal Transition and Senescence in the Retinal Pigment Epithelium of NFE2L2/PGC-1α Double Knock-Out Mice.
Volume: 22
Issue: 4
Publication
First Author: Wang S
Year: 2022
Journal: Autophagy
Title: Loss of acinar cell VMP1 triggers spontaneous pancreatitis in mice.
Volume: 18
Issue: 7
Pages: 1572-1582
Publication
First Author: Pajares M
Year: 2018
Journal: Autophagy
Title: Transcription factor NFE2L2/NRF2 modulates chaperone-mediated autophagy through the regulation of LAMP2A.
Volume: 14
Issue: 8
Pages: 1310-1322
Publication
First Author: Taguchi K
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Keap1 degradation by autophagy for the maintenance of redox homeostasis.
Volume: 109
Issue: 34
Pages: 13561-6
Publication
First Author: Baardman J
Year: 2018
Journal: Cell Rep
Title: A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia.
Volume: 25
Issue: 8
Pages: 2044-2052.e5
Publication
First Author: Okada K
Year: 2008
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Ursodeoxycholic acid stimulates Nrf2-mediated hepatocellular transport, detoxification, and antioxidative stress systems in mice.
Volume: 295
Issue: 4
Pages: G735-47
Publication
First Author: Gbotosho OT
Year: 2019
Journal: Br J Haematol
Title: Cardiac expression of HMOX1 and PGF in sickle cell mice and haem-treated wild type mice dominates organ expression profiles via Nrf2 (Nfe2l2).
Volume: 187
Issue: 5
Pages: 666-675
Publication
First Author: Vargas MR
Year: 2008
Journal: J Neurosci
Title: Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis.
Volume: 28
Issue: 50
Pages: 13574-81
Publication
First Author: Molina-Gonzalez I
Year: 2023
Journal: Nat Commun
Title: Astrocyte-oligodendrocyte interaction regulates central nervous system regeneration.
Volume: 14
Issue: 1
Pages: 3372
Publication
First Author: Lee DH
Year: 2020
Journal: Autophagy
Title: SQSTM1/p62 activates NFE2L2/NRF2 via ULK1-mediated autophagic KEAP1 degradation and protects mouse liver from lipotoxicity.
Volume: 16
Issue: 11
Pages: 1949-1973
Publication
First Author: Hadano S
Year: 2016
Journal: Hum Mol Genet
Title: Functional links between SQSTM1 and ALS2 in the pathogenesis of ALS: cumulative impact on the protection against mutant SOD1-mediated motor dysfunction in mice.
Volume: 25
Issue: 15
Pages: 3321-3340
Publication
First Author: Reisman SA
Year: 2009
Journal: Toxicol Sci
Title: Increased Nrf2 activation in livers from Keap1-knockdown mice increases expression of cytoprotective genes that detoxify electrophiles more than those that detoxify reactive oxygen species.
Volume: 108
Issue: 1
Pages: 35-47
Publication
First Author: Osburn WO
Year: 2008
Journal: Toxicol Sci
Title: Genetic or pharmacologic amplification of nrf2 signaling inhibits acute inflammatory liver injury in mice.
Volume: 104
Issue: 1
Pages: 218-27
Publication
First Author: Yates MS
Year: 2009
Journal: Carcinogenesis
Title: Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice.
Volume: 30
Issue: 6
Pages: 1024-31
Publication
First Author: Zhang YK
Year: 2013
Journal: PLoS One
Title: Genetic activation of Nrf2 protects against fasting-induced oxidative stress in livers of mice.
Volume: 8
Issue: 3
Pages: e59122
Publication
First Author: Wu KC
Year: 2012
Journal: Toxicol Appl Pharmacol
Title: Nrf2 activation prevents cadmium-induced acute liver injury.
Volume: 263
Issue: 1
Pages: 14-20
Publication
First Author: Paul MK
Year: 2014
Journal: Cell Stem Cell
Title: Dynamic changes in intracellular ROS levels regulate airway basal stem cell homeostasis through Nrf2-dependent Notch signaling.
Volume: 15
Issue: 2
Pages: 199-214
Publication
First Author: Wu KC
Year: 2012
Journal: Toxicol Appl Pharmacol
Title: Role of Nrf2 in preventing ethanol-induced oxidative stress and lipid accumulation.
Volume: 262
Issue: 3
Pages: 321-9
Publication
First Author: Wakabayashi N
Year: 2014
Journal: Mol Cell Biol
Title: Notch-Nrf2 axis: regulation of Nrf2 gene expression and cytoprotection by notch signaling.
Volume: 34
Issue: 4
Pages: 653-63
Publication
First Author: Lu YF
Year: 2014
Journal: PLoS One
Title: Overexpression of Nrf2 protects against microcystin-induced hepatotoxicity in mice.
Volume: 9
Issue: 3
Pages: e93013
Publication
First Author: Garstkiewicz M
Year: 2017
Journal: Eur J Immunol
Title: Opposing effects of Nrf2 and Nrf2-activating compounds on the NLRP3 inflammasome independent of Nrf2-mediated gene expression.
Volume: 47
Issue: 5
Pages: 806-817
Publication
First Author: Keleku-Lukwete N
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Amelioration of inflammation and tissue damage in sickle cell model mice by Nrf2 activation.
Volume: 112
Issue: 39
Pages: 12169-74
Publication
First Author: Okawa H
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity.
Volume: 339
Issue: 1
Pages: 79-88
Publication
First Author: Toyama T
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Cytoprotective role of Nrf2/Keap1 system in methylmercury toxicity.
Volume: 363
Issue: 3
Pages: 645-50
Publication
First Author: Wu KC
Year: 2011
Journal: Toxicol Sci
Title: Beneficial role of Nrf2 in regulating NADPH generation and consumption.
Volume: 123
Issue: 2
Pages: 590-600
Publication
First Author: Wu KC
Year: 2012
Journal: PLoS One
Title: Effect of graded Nrf2 activation on phase-I and -II drug metabolizing enzymes and transporters in mouse liver.
Volume: 7
Issue: 7
Pages: e39006
Publication  
First Author: Murakami S
Year: 2017
Journal: Mol Cell Biol
Title: NRF2 Activation Impairs Quiescence and Bone Marrow Reconstitution Capacity of Hematopoietic Stem Cells.
Volume: 37
Issue: 19
Publication
First Author: Hiebert P
Year: 2018
Journal: Dev Cell
Title: Nrf2-Mediated Fibroblast Reprogramming Drives Cellular Senescence by Targeting the Matrisome.
Volume: 46
Issue: 2
Pages: 145-161.e10
Publication
First Author: Ye X
Year: 2023
Journal: Commun Biol
Title: Sulforaphane decreases serum selenoprotein P levels through enhancement of lysosomal degradation independent of Nrf2.
Volume: 6
Issue: 1
Pages: 1060
Publication  
First Author: Kobayashi EH
Year: 2016
Journal: Nat Commun
Title: Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription.
Volume: 7
Pages: 11624
Publication
First Author: Vargas MR
Year: 2013
Journal: PLoS One
Title: Absence of Nrf2 or its selective overexpression in neurons and muscle does not affect survival in ALS-linked mutant hSOD1 mouse models.
Volume: 8
Issue: 2
Pages: e56625
Publication  
First Author: Nezu M
Year: 2017
Journal: Sci Signal
Title: Nrf2 inactivation enhances placental angiogenesis in a preeclampsia mouse model and improves maternal and fetal outcomes.
Volume: 10
Issue: 479
Publication
First Author: Ohtsuji M
Year: 2008
Journal: J Biol Chem
Title: Nrf1 and Nrf2 play distinct roles in activation of antioxidant response element-dependent genes.
Volume: 283
Issue: 48
Pages: 33554-62
Publication
First Author: Goto M
Year: 2015
Journal: Genes Cells
Title: Alcohol dehydrogenase 3 contributes to the protection of liver from nonalcoholic steatohepatitis.
Volume: 20
Issue: 6
Pages: 464-80
Publication
First Author: Furusawa Y
Year: 2014
Journal: Genes Cells
Title: Nrf2 induces fibroblast growth factor 21 in diabetic mice.
Volume: 19
Issue: 12
Pages: 864-78
Publication  
First Author: Kim EY
Year: 2022
Journal: Antioxidants (Basel)
Title: NRF2 Activation in Autophagy Defects Suppresses a Pharmacological Transactivation of the Nuclear Receptor FXR.
Volume: 11
Issue: 2
Publication
First Author: Hamada S
Year: 2018
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Simultaneous K-ras activation and Keap1 deletion cause atrophy of pancreatic parenchyma.
Volume: 314
Issue: 1
Pages: G65-G74
Publication  
First Author: Uruno A
Year: 2020
Journal: Mol Cell Biol
Title: Nrf2 Suppresses Oxidative Stress and Inflammation in App Knock-In Alzheimer's Disease Model Mice.
Volume: 40
Issue: 6
Publication  
First Author: Kim EY
Year: 2022
Journal: Cells
Title: Basal Autophagy Is Necessary for A Pharmacologic PPARα Transactivation.
Volume: 11
Issue: 4
Publication  
First Author: Wakabayashi N
Year: 2023
Journal: Int J Mol Sci
Title: Forced Hepatic Expression of NRF2 or NQO1 Impedes Hepatocyte Lipid Accumulation in a Lipodystrophy Mouse Model.
Volume: 24
Issue: 17
Publication
First Author: Hirotsu Y
Year: 2012
Journal: Mol Cell Biol
Title: NF-E2-related factor 1 (Nrf1) serves as a novel regulator of hepatic lipid metabolism through regulation of the Lipin1 and PGC-1β genes.
Volume: 32
Issue: 14
Pages: 2760-70
Publication
First Author: Yagishita Y
Year: 2014
Journal: Diabetes
Title: Nrf2 protects pancreatic β-cells from oxidative and nitrosative stress in diabetic model mice.
Volume: 63
Issue: 2
Pages: 605-18
Publication  
First Author: Suzuki T
Year: 2017
Journal: Nat Commun
Title: Hyperactivation of Nrf2 in early tubular development induces nephrogenic diabetes insipidus.
Volume: 8
Pages: 14577
Publication
First Author: Uruno A
Year: 2013
Journal: Mol Cell Biol
Title: The Keap1-Nrf2 system prevents onset of diabetes mellitus.
Volume: 33
Issue: 15
Pages: 2996-3010
Publication
First Author: Mitsuishi Y
Year: 2012
Journal: Cancer Cell
Title: Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming.
Volume: 22
Issue: 1
Pages: 66-79
Publication
First Author: Inoue D
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Inducible disruption of autophagy in the lung causes airway hyper-responsiveness.
Volume: 405
Issue: 1
Pages: 13-8
Publication
First Author: Taguchi K
Year: 2014
Journal: Mol Cell Biol
Title: Nrf2 enhances cholangiocyte expansion in Pten-deficient livers.
Volume: 34
Issue: 5
Pages: 900-13
Publication  
First Author: Suzuki T
Year: 2017
Journal: Mol Cell Biol
Title: Systemic Activation of NRF2 Alleviates Lethal Autoimmune Inflammation in Scurfy Mice.
Volume: 37
Issue: 15
Publication
First Author: Taguchi K
Year: 2010
Journal: Mol Cell Biol
Title: Genetic analysis of cytoprotective functions supported by graded expression of Keap1.
Volume: 30
Issue: 12
Pages: 3016-26
Publication  
First Author: Baird L
Year: 2023
Journal: Redox Biol
Title: A NRF2-induced secretory phenotype activates immune surveillance to remove irreparably damaged cells.
Volume: 66
Pages: 102845
Publication  
First Author: Chartoumpekis DV
Year: 2018
Journal: JCI Insight
Title: Nrf2 prevents Notch-induced insulin resistance and tumorigenesis in mice.
Volume: 3
Issue: 5
Publication  
First Author: Fragoulis A
Year: 2022
Journal: Redox Biol
Title: Nrf2 induces malignant transformation of hepatic progenitor cells by inducing β-catenin expression.
Volume: 57
Pages: 102453
Publication
First Author: Wakabayashi N
Year: 2010
Journal: Sci Signal
Title: Regulation of notch1 signaling by nrf2: implications for tissue regeneration.
Volume: 3
Issue: 130
Pages: ra52
Publication
First Author: Uruno A
Year: 2016
Journal: Mol Cell Biol
Title: Nrf2-Mediated Regulation of Skeletal Muscle Glycogen Metabolism.
Volume: 36
Issue: 11
Pages: 1655-72
Publication
First Author: Komatsu M
Year: 2010
Journal: Nat Cell Biol
Title: The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1.
Volume: 12
Issue: 3
Pages: 213-23
Publication
First Author: Yagishita Y
Year: 2017
Journal: Cell Rep
Title: Nrf2 Improves Leptin and Insulin Resistance Provoked by Hypothalamic Oxidative Stress.
Volume: 18
Issue: 8
Pages: 2030-2044
Publication
First Author: Vallelian F
Year: 2022
Journal: Cell Death Differ
Title: Heme-stress activated NRF2 skews fate trajectories of bone marrow cells from dendritic cells towards red pulp-like macrophages in hemolytic anemia.
Volume: 29
Issue: 8
Pages: 1450-1465
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Itoh K
Year: 1997
Journal: Biochem Biophys Res Commun
Title: An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements.
Volume: 236
Issue: 2
Pages: 313-22
Publication
First Author: Chanas SA
Year: 2002
Journal: Biochem J
Title: Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice.
Volume: 365
Issue: Pt 2
Pages: 405-16
Publication
First Author: Chan K
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development.
Volume: 93
Issue: 24
Pages: 13943-8
Publication
First Author: Ramos-Gomez M
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice.
Volume: 98
Issue: 6
Pages: 3410-5
Publication
First Author: Thimmulappa RK
Year: 2006
Journal: J Clin Invest
Title: Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis.
Volume: 116
Issue: 4
Pages: 984-95
Publication
First Author: Zhou W
Year: 2007
Journal: Mol Cell Endocrinol
Title: ERRbeta: a potent inhibitor of Nrf2 transcriptional activity.
Volume: 278
Issue: 1-2
Pages: 52-62
Publication  
First Author: Sarad K
Year: 2023
Journal: Front Immunol
Title: Single-cell transcriptomics reveals subtype-specific molecular profiles in Nrf2-deficient macrophages from murine atherosclerotic aortas.
Volume: 14
Pages: 1249379
Publication
First Author: Ghosh D
Year: 2014
Journal: Neurobiol Aging
Title: Dual-energy precursor and nuclear erythroid-related factor 2 activator treatment additively improve redox glutathione levels and neuron survival in aging and Alzheimer mouse neurons upstream of reactive oxygen species.
Volume: 35
Issue: 1
Pages: 179-90
Publication
First Author: Yu S
Year: 2010
Journal: PLoS One
Title: Nrf2 expression is regulated by epigenetic mechanisms in prostate cancer of TRAMP mice.
Volume: 5
Issue: 1
Pages: e8579
Publication
First Author: Tapias V
Year: 2018
Journal: Hum Mol Genet
Title: Benfotiamine treatment activates the Nrf2/ARE pathway and is neuroprotective in a transgenic mouse model of tauopathy.
Volume: 27
Issue: 16
Pages: 2874-2892
Publication
First Author: Hoang TT
Year: 2019
Journal: J Biol Chem
Title: Angiogenin activates the astrocytic Nrf2/antioxidant-response element pathway and thereby protects murine neurons from oxidative stress.
Volume: 294
Issue: 41
Pages: 15095-15103
Publication
First Author: Ngo HKC
Year: 2017
Journal: Cancer Res
Title: Nrf2 Mutagenic Activation Drives Hepatocarcinogenesis.
Volume: 77
Issue: 18
Pages: 4797-4808
Publication
First Author: Chartoumpekis DV
Year: 2018
Journal: Am J Physiol Endocrinol Metab
Title: Nrf2 deletion from adipocytes, but not hepatocytes, potentiates systemic metabolic dysfunction after long-term high-fat diet-induced obesity in mice.
Volume: 315
Issue: 2
Pages: E180-E195
Publication  
First Author: Sha LK
Year: 2015
Journal: Free Radic Biol Med
Title: Loss of Nrf2 in bone marrow-derived macrophages impairs antigen-driven CD8(+) T cell function by limiting GSH and Cys availability.
Volume: 83
Pages: 77-88
Publication  
First Author: Takagi T
Year: 2014
Journal: Free Radic Biol Med
Title: Temporal activation of Nrf2 in the penumbra and Nrf2 activator-mediated neuroprotection in ischemia-reperfusion injury.
Volume: 72
Pages: 124-33
Publication
First Author: Cui W
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Potential role for Nrf2 activation in the therapeutic effect of MG132 on diabetic nephropathy in OVE26 diabetic mice.
Volume: 304
Issue: 1
Pages: E87-99
Publication
First Author: Xi C
Year: 2023
Journal: Blood
Title: Nrf2 sensitizes ferroptosis through l-2-hydroxyglutarate-mediated chromatin modifications in sickle cell disease.
Volume: 142
Issue: 4
Pages: 382-396
Publication
First Author: Faes C
Year: 2020
Journal: Exp Physiol
Title: Effects of hypoxia-reoxygenation stimuli on renal redox status and nuclear factor erythroid 2-related factor 2 pathway in sickle cell SAD mice.
Volume: 105
Issue: 2
Pages: 357-369
Publication
First Author: Zhang L
Year: 2016
Journal: Am J Transl Res
Title: Adipose-specific ablation of Nrf2 transiently delayed high-fat diet-induced obesity by altering glucose, lipid and energy metabolism of male mice.
Volume: 8
Issue: 12
Pages: 5309-5319